Platelet Disorders

Common Name(s)

Platelet Disorders

Description for this condition is not yet available.
 

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Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Platelet Disorders" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Platelet Disorders" returned 61 free, full-text research articles on human participants. First 3 results:

Platelet indices may be correlated with severity of vasospastic disorders.
 

Author(s): Murat Kadan, Kubilay Karabacak, Erkan Kaya, Gökhan Arslan, Gökhan Erol, Suat Doğancı, Vedat Yıldırım, Cengiz Bolcal, Ufuk Demirkılıç

Journal:

 

BACKGROUND Vasospastic disorders are common worldwide. In daily practice, routine blood samples are used for several investigations. In this study we aimed to determine the possible correlations between lymphocyte count, platelet indices, and the severity of vasospastic disorders. ...

Last Updated: 15 Apr 2015

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Functional and molecular characterization of inherited platelet disorders in the Iberian Peninsula: results from a collaborative study.
 

Author(s): Isabel Sánchez-Guiu, Ana I Antón, José Padilla, Francisco Velasco, José F Lucia, Miguel Lozano, Ana Rosa Cid, Teresa Sevivas, María F Lopez-Fernandez, Vicente Vicente, Consuelo González-Manchón, José Rivera, María L Lozano

Journal:

 

The diagnostic evaluation of inherited platelet disorders (IPDs) is complicated and time-consuming, resulting in a relevant number of undiagnosed and incorrectly classified patients. In order to evaluate the spectrum of IPDs in individuals with clinical suspicion of these disorders, ...

Last Updated: 28 Apr 2015

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Tat 101-mediated enhancement of brain pericyte migration involves platelet-derived growth factor subunit B homodimer: implications for human immunodeficiency virus-associated neurocognitive disorders.
 

Author(s): Fang Niu, Honghong Yao, Wenting Zhang, Roy Lee Sutliff, Shilpa Buch

Journal: J. Neurosci.. 2014 Aug;34(35):11812-25.

 

In the era of antiretroviral therapy, although the human immunodeficiency virus (HIV) replication can be successfully controlled, complications of the CNS continue to affect infected individuals. Viral Tat protein is not only neurotoxic but has also been shown to disrupt the integrity ...

Last Updated: 28 Aug 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Platelet Disorders" returned 19 free, full-text review articles on human participants. First 3 results:

Genetic basis of congenital platelet disorders.
 

Author(s): Jesse Hinckley, Jorge Di Paola

Journal: Hematology Am Soc Hematol Educ Program. 2014 Dec;2014(1):337-42.

 

Over the past 4 decades, a better understanding of the genetic origins of inherited platelet disorders has illuminated avenues of investigation in megakaryopoiesis and has identified targets of pharmacologic intervention. Many of these discoveries have been translated into clinical ...

Last Updated: 20 Feb 2015

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Laboratory diagnostics of inherited platelet disorders.
 

Author(s): Cecilia Carubbi, Elena Masselli, Antonio Nouvenne, Domenico Russo, Daniela Galli, Prisco Mirandola, Giuliana Gobbi, Marco Vitale

Journal: Clin. Chem. Lab. Med.. 2014 Aug;52(8):1091-106.

 

Abstract Inherited platelet disorders (IPDs) are the general and common denomination of a broad number of different rare and congenital pathologies affecting platelets. Even if these disorders are characterized by widely heterogeneous clinical presentations, all of them are commonly ...

Last Updated: 28 Jun 2014

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The contribution of platelet studies to the understanding of disease mechanisms in complex and monogenetic neurological disorders.
 

Author(s): Christophe Goubau, Gunnar M Buyse, Chris Van Geet, Kathleen Freson

Journal: Dev Med Child Neurol. 2014 Aug;56(8):724-31.

 

Platelets, known for their role in primary haemostasis, prevent excessive bleeding after injury. The study of platelets has, therefore, traditionally focused on bleeding disorders. It has recently become evident, however, that platelet research can contribute to unravelling the disease ...

Last Updated: 21 Jul 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Thrombocytopathy in Gaucher Disease Patients
 

Status: Recruiting

Condition Summary: Gaucher Disease; Thrombocytopathy

 

Last Updated: 27 Apr 2011

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Use of Proteomics for the Diagnosis of a Platelet-related Bleeding Disorder
 

Status: Not yet recruiting

Condition Summary: Inherited Platelet Disorders

 

Last Updated: 19 Apr 2015

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Safety and Efficacy of Eltrombopag at Escalated Doses
 

Status: Recruiting

Condition Summary: Immune Thrombocytopenia; Platelet Disorder

 

Last Updated: 17 Jun 2013

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