Platelet Disorders

Common Name(s)

Platelet Disorders

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Platelet Disorders" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Platelet Disorders" returned 64 free, full-text research articles on human participants. First 3 results:

Haematological spectrum and genotype-phenotype correlations in nine unrelated families with RUNX1 mutations from the French network on inherited platelet disorders.
 

Author(s): Veronique Latger-Cannard, Christophe Philippe, Alexandre Bouquet, Veronique Baccini, Marie-Christine Alessi, Annick Ankri, Anne Bauters, Sophie Bayart, Pascale Cornillet-Lefebvre, Sylvie Daliphard, Marie-Joelle Mozziconacci, Aline Renneville, Paola Ballerini, Guy Leverger, Hagay Sobol, Philippe Jonveaux, Claude Preudhomme, Paquita Nurden, Thomas Lecompte, Remi Favier

Journal:

 

Less than 50 patients with FPD/AML (OMIM 601309) have been reported as of today and there may an underestimation. The purpose of this study was to describe the natural history, the haematological features and the genotype-phenotype correlations of this entity in order to, first, screen ...

Last Updated: 26 Apr 2016

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Heavy Menstrual Bleeding as a Common Presenting Symptom of Rare Platelet Disorders: Illustrative Case Examples.
 

Author(s): Madhvi Rajpurkar, Sarah H O'Brien, Fareeda W Haamid, David L Cooper, Sriya Gunawardena, Meera Chitlur

Journal: J Pediatr Adolesc Gynecol. 2016 Dec;29(6):537-541.

 

Heavy menstrual bleeding (HMB) is a common symptom in patients who present to the obstetrician-gynecologist or adolescent medicine specialist and might result from an underlying inherited bleeding disorder. Whereas relatively common bleeding disorders such as von Willebrand disease ...

Last Updated: 22 Jul 2016

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Super-resolution microscopy as a potential approach to diagnosis of platelet granule disorders.
 

Author(s): D Westmoreland, M Shaw, W Grimes, D J Metcalf, J J Burden, K Gomez, A E Knight, D F Cutler

Journal: J. Thromb. Haemost.. 2016 Apr;14(4):839-49.

 

Many platelet functions are dependent on bioactive molecules released from their granules. Deficiencies of these granules in number, shape or content are associated with bleeding. The small size of these granules is such that imaging them for diagnosis has traditionally required electron ...

Last Updated: 11 Apr 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Platelet Disorders" returned 26 free, full-text review articles on human participants. First 3 results:

Inherited platelet disorders: Insight from platelet genomics using next-generation sequencing.
 

Author(s): Annabel Maclachlan, Steve P Watson, Neil V Morgan

Journal: Platelets. 2017 Jan;28(1):14-19.

 

Inherited platelet disorders (IPDs) are a heterogeneous group of disorders associated with normal or reduced platelet counts and bleeding diatheses of varying severities. The identification of the underlying cause of IPDs is clinically challenging due to the absence of a gold-standard ...

Last Updated: 27 Jun 2016

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Comparison of different platelet count thresholds to guide administration of prophylactic platelet transfusion for preventing bleeding in people with haematological disorders after myelosuppressive chemotherapy or stem cell transplantation.
 

Author(s): Lise J Estcourt, Simon J Stanworth, Carolyn Doree, Sally Hopewell, Marialena Trivella, Michael F Murphy

Journal:

 

Platelet transfusions are used in modern clinical practice to prevent and treat bleeding in people who are thrombocytopenic due to bone marrow failure. Although considerable advances have been made in platelet transfusion therapy in the last 40 years, some areas continue to provoke ...

Last Updated: 1 Dec 2015

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Different doses of prophylactic platelet transfusion for preventing bleeding in people with haematological disorders after myelosuppressive chemotherapy or stem cell transplantation.
 

Author(s): Lise J Estcourt, Simon Stanworth, Carolyn Doree, Marialena Trivella, Sally Hopewell, Patricia Blanco, Michael F Murphy

Journal:

 

Platelet transfusions are used in modern clinical practice to prevent and treat bleeding in people who are thrombocytopenic due to bone marrow failure. Although considerable advances have been made in platelet transfusion therapy in the last 40 years, some areas continue to provoke ...

Last Updated: 2 Nov 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Thrombocytopathy in Gaucher Disease Patients
 

Status: Recruiting

Condition Summary: Gaucher Disease; Thrombocytopathy

 

Last Updated: 27 Oct 2016

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Use of Proteomics for the Diagnosis of a Platelet-related Bleeding Disorder
 

Status: Not yet recruiting

Condition Summary: Inherited Platelet Disorders

 

Last Updated: 23 Mar 2016

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Safety and Efficacy of Eltrombopag at Escalated Doses
 

Status: Recruiting

Condition Summary: Immune Thrombocytopenia; Platelet Disorder

 

Last Updated: 30 Jan 2017

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