Pineoblastoma

Common Name(s)

Pineoblastoma

Pineoblastoma is a cancerous (malignant) tumor that develops in the pineal gland.  The pineal gland is located in the brain and makes the hormone melatonin to regulate the body's sleep patterns.  Pineoblastoma is a type of primitive neuroectodermal tumor (PNET).  Pineoblastoma mainly affects children, but can also occur in adults.   Treatment of pineoblastoma includes surgery to remove as much of the tumor as possible, followed by radiation therapy and chemotherapy.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Pineoblastoma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Pineoblastoma" returned 11 free, full-text research articles on human participants. First 3 results:

Evaluation of age-dependent treatment strategies for children and young adults with pineoblastoma: analysis of pooled European Society for Paediatric Oncology (SIOP-E) and US Head Start data.
 

Author(s): Martin Mynarek, Barry Pizer, Christelle Dufour, Dannis van Vuurden, Miklos Garami, Maura Massimino, Jason Fangusaro, Tom Davidson, Maria Joao Gil-da-Costa, Jaroslav Sterba, Martin Benesch, Nicolas Gerber, B Ole Juhnke, Robert Kwiecien, Torsten Pietsch, Marcel Kool, Steve Clifford, David W Ellison, Felice Giangaspero, Pieter Wesseling, Floyd Gilles, Nicholas Gottardo, Jonathan L Finlay, Stefan Rutkowski, Katja von Hoff

Journal: Neuro-oncology. 2017 04;19(4):576-585.

 

Pineoblastoma is a rare pineal region brain tumor. Treatment strategies have reflected those for other malignant embryonal brain tumors.

Last Updated: 31 Dec 1969

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MRI-based assessment of the pineal gland in a large population of children aged 0-5 years and comparison with pineoblastoma: part II, the cystic gland.
 

Author(s): Selma Sirin, Marcus C de Jong, Paolo Galluzzi, Philippe Maeder, Hervé J Brisse, Jonas A Castelijns, Pim de Graaf, Sophia L Goericke,

Journal: Neuroradiology. 2016 Jul;58(7):713-21.

 

Pineal cysts are a common incidental finding on brain MRI with resulting difficulties in differentiation between normal glands and pineal pathologies. The aim of this study was to assess the size and morphology of the cystic pineal gland in children (0-5 years) and compare the findings ...

Last Updated: 31 Dec 1969

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MRI-based assessment of the pineal gland in a large population of children aged 0-5 years and comparison with pineoblastoma: part I, the solid gland.
 

Author(s): Paolo Galluzzi, Marcus C de Jong, Selma Sirin, Philippe Maeder, Pietro Piu, Alfonso Cerase, Lucia Monti, Hervé J Brisse, Jonas A Castelijns, Pim de Graaf, Sophia L Goericke,

Journal: Neuroradiology. 2016 Jul;58(7):705-12.

 

Differentiation between normal solid (non-cystic) pineal glands and pineal pathologies on brain MRI is difficult. The aim of this study was to assess the size of the solid pineal gland in children (0-5 years) and compare the findings with published pineoblastoma cases.

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Pineoblastoma" returned 2 free, full-text review articles on human participants. First 3 results:

The long-term postsurgical prognosis of patients with pineoblastoma.
 

Author(s): Matthew Tate, Michael E Sughrue, Martin J Rutkowski, Ari J Kane, Derick Aranda, Lashaun McClinton, Lashay McClinton, Igor J Barani, Andrew T Parsa

Journal: Cancer. 2012 Jan;118(1):173-9.

 

For this report, the authors comprehensively summarized the existing literature on patients with pineoblastoma and identified the variables and treatments that had an impact patient on outcomes.

Last Updated: 31 Dec 1969

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[Spinal dissemination of pineoblastoma five years after irradiation of a pineal tumor. Case report].
 

Author(s): M Hamasaki, K Kuwamura, Y Nishida

Journal: Neurol. Med. Chir. (Tokyo). 1987 Nov;27(11):1109-13.

 

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

International HIT-MED Registry (I-HIT-MED)
 

Status: Recruiting

Condition Summary: Childhood Brain Tumor

 

Last Updated: 17 Oct 2017

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Chemotherapy and Radiation Therapy in Treating Young Patients With Newly Diagnosed, Previously Untreated, High-Risk Medulloblastoma
 

Status: Recruiting

Condition Summary: Untreated Childhood Medulloblastoma; Untreated Childhood Pineoblastoma; Untreated Childhood Supratentorial Primitive Neuroectodermal Tumor

 

Last Updated: 29 Aug 2017

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