Piebaldism

Common Name(s)

Piebaldism

Piebaldism is a rare inherited condition characterized by a white forelock (a patch of white hair directly above the forehead). The name piebaldism is derived from the words ÒpieÓ (from magpie, which is a black and white bird) and ÒbaldÓ (from the bald eagle, the US national bird that has a white feathered head). Other features include a white patch on the central portion of the forehead; white eyebrow and eyelash hair; and white patches of skin on the face (particularly the chin), trunk and extremities (hands and feet are not usually affected). This condition is present at birth and usually remains unchanged throughout life. It is inherited in an autosomal dominant fashion and is caused by mutations in the KIT gene.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Piebaldism" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Piebaldism" returned 18 free, full-text research articles on human participants. First 3 results:

A novel splicing mutation of KIT results in piebaldism and auburn hair color in a Chinese family.
 

Author(s): Yong-jia Yang, Rui Zhao, Xin-yu He, Li-ping Li, Ke-wei Wang, Liu Zhao, Ming Tu, Jin-song Tang, Zhi-guo Xie, Yi-min Zhu

Journal: Biomed Res Int. 2013 ;2013():689756.

 

Piebaldism is a rare autosomal dominant disorder of melanocyte development, which is mostly caused by KIT gene. The key characteristics of piebaldism include localized poliosis, congenital leukoderma, and other variable manifestations. The previous study has illustrated that the homogeneous ...

Last Updated: 3 Sep 2013

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A novel mutation of the KIT gene in a Chinese family with piebaldism.
 

Author(s): Guang-Dong Wen, Cheng Zhou, Cong Yu, Juan DU, Qian-Xi Xu, Zheng-Yi Liu, Jian-Zhong Zhang

Journal: Chin. Med. J.. 2013 Jun;126(12):2325-8.

 

Human piebaldism is a rare autosomal dominant condition characterized by congenital white forelock and depigmented patches of skin, typically on the forehead, anterior trunk and extremities. Mutations in the KIT gene have been proposed to be responsible for the underlying changes ...

Last Updated: 21 Jun 2013

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Piebaldism and neurofibromatosis: state of knowledge.
 

Author(s): Ana Duarte, Alberto Mota, Teresa Baudrier, Paulo Morais, António Santos, Rita Cerqueira, Purificação Tavares, Filomena Azevedo

Journal:

 

Despite progress in understanding the molecular basis, the diagnosis of neurofibromatosis 1 (NF 1) is based on clinical criteria, established by the National Institute of Health (NIH) Consensus Conference in 1987. The association of NF1 and piebaldism has been reported, but some authors ...

Last Updated: 4 Feb 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Piebaldism" returned 1 free, full-text review articles on human participants. First 3 results:

Piebaldism in a 2-year-old girl.
 

Author(s): Verónica López, Esperanza Jordá

Journal:

 

Piebaldism is a rare autosomal dominant skin disorder characterized by a white forelock and depigmented patches of skin, generally located on the forehead, central chest and abdomen, upper arms, and lower extremities. We report a case of a 2-year-old girl with a typical presentation ...

Last Updated: 8 Mar 2011

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Punchgrafting Techniques for Vitiligo
 

Status: Recruiting

Condition Summary: Non-segmental Vitiligo; Segmental Vitiligo; Piebaldism

 

Last Updated: 20 Jun 2011

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Natural History of Diseases Associated With Allergic Inflammation: Atopic Dermatitis and Genetic and Congenital Diseases Associated With Atopic Pathways
 

Status: Recruiting

Condition Summary: Atopic Dermatitis; Netheron's Syndrome; Piebaldism; Hyper IgE Syndrome; Ichthyosis; Anaphylaxis; Severe Allergy

 

Last Updated: 21 Jun 2014

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