Pheochromocytoma

Common Name(s)

Pheochromocytoma, Adrenal gland tumor

Pheochromocytomas are rare tumors of the adrenal glands, which are located right above the kidneys. Although they are usually not cancerous (benign), pheochromocytomas often cause the adrenal glands to make too many stress hormones called epinephrines and norepinephrines. This can lead to high blood pressure and cause symptoms such as severe headaches, irritability, sweating, rapid heart rate, nausea, vomiting, weight loss, weakness, chest pain, and a feeling of anxiety. Rarely, this kind of tumor occurs outside the adrenal gland, usually somewhere in the abdomen, and are called extra-adrenal pheochromocytomas or paragangliomas. Pheochromocytomas can occur in certain familial genetic syndromes.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Pheochromocytoma" for support, advocacy or research.

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National Adrenal Diseases Foundation (NADF)

The National Adrenal Diseases Foundation informs, educates, and supports those with adrenal disease and their families to improve their quality of life.

Last Updated: 13 Oct 2014

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Pheo Para Alliance

To provide a resource to patients, healthcare providers and researchers that offers value. To "spread the word" about Pheochromocytoma and Paraganglioma and to help educate and provide knowledge that assists in the search for a cure...

Last Updated: 10 Feb 2015

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VHL Alliance

VHLA is dedicated to research, education, and support to improve awareness, diagnosis, treatment, and quality of life for those affected by VHL.

Last Updated: 5 Jan 2015

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Pheochromocytoma" for support, advocacy or research.

Logo
National Adrenal Diseases Foundation (NADF)

The National Adrenal Diseases Foundation informs, educates, and supports those with adrenal disease and their families to improve their quality of life.

http://www.nadf.us

Last Updated: 13 Oct 2014

View Details
Pheo Para Alliance

To provide a resource to patients, healthcare providers and researchers that offers value. To "spread the word" about Pheochromocytoma and Paraganglioma and to help educate and provide knowledge that assists in the search for a cure...

http://www.pheo-para-alliance.org

Last Updated: 10 Feb 2015

View Details
VHL Alliance

VHLA is dedicated to research, education, and support to improve awareness, diagnosis, treatment, and quality of life for those affected by VHL.

http://www.vhl.org

Last Updated: 5 Jan 2015

View Details

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Pheochromocytoma" returned 734 free, full-text research articles on human participants. First 3 results:

Somatostatin-secreting Pheochromocytoma Mimicking Insulin-dependent Diabetes Mellitus.
 

Author(s): Hiroyuki Hirai, Sanae Midorikawa, Shinichi Suzuki, Hironobu Sasano, Tsuyoshi Watanabe, Hiroaki Satoh

Journal: Intern. Med.. ;55(20):2985-2991.

 

We herein present the findings of a 42-year-old woman with either adrenal pheochromocytoma or intraadrenal paraganglioma that simultaneously secreted somatostatin, thus mimicking insulin-dependent diabetes mellitus. Pheochromocytoma was clinically diagnosed based on scintigraphy, ...

Last Updated: 17 Oct 2016

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(68)Ga-DOTATATE and (18)F-FDG PET/CT in Paraganglioma and Pheochromocytoma: utility, patterns and heterogeneity.
 

Author(s): Chian A Chang, David A Pattison, Richard W Tothill, Grace Kong, Tim J Akhurst, Rodney J Hicks, Michael S Hofman

Journal:

 

Pheochromocytomas (PCC) and paragangliomas (PGL) are neuroendocrine tumours arising from pluripotent neural crest stem cells and are associated with neurons of the autonomic nervous system. PCCs/PGLs are often hereditary and multifocal, and their biologic behaviour and metabolic activity ...

Last Updated: 18 Aug 2016

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A rare case of Ganglioneuroblastoma Encapsulated in Pheochromocytoma.
 

Author(s): Nathália Vieira Sousa, Luísa Coelho Marques de Oliveira, Paulo José Oliveira Cortez, Vitor Engrácia Valenti, David Mathew Garner, Roseane de Souza Candido Irulegui, Dalmo Antônio Ribeiro Moreira

Journal: Acta Medica (Hradec Kralove). ;59(2):67-9.

 

Pheochromocytoma and Ganglioneuroblastoma are separate diseases and a rare combination in which the diagnosis can only be confirmed by pathological examination after tumor excision. We reported here a case of ganglioneuroblastoma encapsulated in pheochromocytoma. The patient is a ...

Last Updated: 16 Aug 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Pheochromocytoma" returned 103 free, full-text review articles on human participants. First 3 results:

Adrenal pheochromocytoma presenting with Takotsubo-pattern cardiomyopathy and acute heart failure: A case report and literature review.
 

Author(s): Yi-Lun Chiang, Pei-Chi Chen, Chin-Cheng Lee, Su-Kiat Chua

Journal: Medicine (Baltimore). 2016 Sep;95(36):e4846.

 

Pheochromocytoma is an endocrine tumor that causes hypertension, facial pallor, and headache. Pheochromocytoma patients rarely present with acute heart failure or cardiogenic shock.

Last Updated: 8 Sep 2016

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Acute and Chronic Pheochromocytoma-Induced Cardiomyopathies: Different Prognoses?: A Systematic Analytical Review.
 

Author(s): Marie Batisse-Lignier, Bruno Pereira, Pascal Motreff, Romain Pierrard, Christelle Burnot, Charles Vorilhon, Salwan Maqdasy, Béatrice Roche, Francoise Desbiez, Guillaume Clerfond, Bernard Citron, Jean-René Lusson, Igor Tauveron, Romain Eschalier

Journal: Medicine (Baltimore). 2015 Dec;94(50):e2198.

 

Pheochromocytoma and paraganglioma (PPG) are rare and late-diagnosed catecholamine secreting tumors, which may be associated with unrecognized and/or severe cardiomyopathies. We performed a computer-assisted systematic search of the electronic Medline databases using the MESH terms ...

Last Updated: 19 Dec 2015

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Pheochromocytoma multisystem crisis treated with emergency surgery: a case report and literature review.
 

Author(s): Katsura Kakoki, Yasuyoshi Miyata, Youhei Shida, Tomoaki Hakariya, Kosuke Takehara, Seiya Izumida, Motohiro Sekino, Naoe Kinoshita, Tsukasa Igawa, Junya Fukuoka, Hideki Sakai

Journal:

 

Pheochromocytoma is a neuroendocrine tumor that predominantly presents with hypertension, palpitations, and tachycardia due to excessive catecholamine excretion. Although pheochromocytoma multisystem crisis (PMC) is relatively rare, urologists and clinicians should focus on early ...

Last Updated: 9 Dec 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Diagnosis of Pheochromocytoma
 

Status: Recruiting

Condition Summary: Pheochromocytoma

 

Last Updated: 24 Jan 2017

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MIBG for Refractory Neuroblastoma and Pheochromocytoma
 

Status: Recruiting

Condition Summary: Relapsed Neuroblastoma; Metastatic Pheochromocytoma

 

Last Updated: 15 Aug 2016

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Phenoxybenzamine Versus Doxazosin in PCC Patients
 

Status: Recruiting

Condition Summary: Pheochromocytoma

 

Last Updated: 25 Oct 2016

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