Peripheral type neurofibromatosis

Common Name(s)

Peripheral type neurofibromatosis

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Peripheral type neurofibromatosis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Peripheral type neurofibromatosis" returned 21 free, full-text research articles on human participants. First 3 results:

Spinal intradural malignant peripheral nerve sheath tumor in a child with neurofibromatosis type 2: the first reported case and literature review.
 

Author(s): Liang Wu, Xiaofeng Deng, Chenlong Yang, Yulun Xu

Journal: Turk Neurosurg. 2014 ;24(1):135-9.

 

Spinal intradural malignant peripheral nerve sheath tumors (MPNSTs) in children are extremely rare, with only five reported cases in the literature. A 9-year-old female with neurofibromatosis type 2 (NF-2) presented with right hip pain and severe weakness of bilateral legs for 3 months. ...

Last Updated: 18 Feb 2014

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Serum biomarkers for neurofibromatosis type 1 and early detection of malignant peripheral nerve-sheath tumors.
 

Author(s): Su-Jin Park, Birgit Sawitzki, Lan Kluwe, Victor F Mautner, Nikola Holtkamp, Andreas Kurtz

Journal:

 

Neurofibromatosis type 1 (NF1) is a hereditary tumor syndrome characterized by the development of benign nerve-sheath tumors, which transform to malignant peripheral nerve-sheath tumors (MPNST) in about 8 to 13% of patients with NF1. MPNST are invasive sarcomas with extremely poor ...

Last Updated: 9 May 2013

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Molecular heterogeneity in malignant peripheral nerve sheath tumors associated with neurofibromatosis type 1.
 

Author(s): Laura Thomas, Victor-Felix Mautner, David N Cooper, Meena Upadhyaya

Journal:

 

Neurofibromatosis type-1 (NF1), resulting from NF1 gene loss of function, is characterized by an increased risk of developing benign and malignant peripheral nerve sheath tumors (MPNSTs). Whereas the cellular heterogeneity of NF1-associated tumors has been well studied, the molecular ...

Last Updated: 20 Dec 2012

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Peripheral type neurofibromatosis" returned 4 free, full-text review articles on human participants. First 3 results:

Survival meta-analyses for >1800 malignant peripheral nerve sheath tumor patients with and without neurofibromatosis type 1.
 

Author(s): Matthias Kolberg, Maren Høland, Trude H Agesen, Helge R Brekke, Knut Liestøl, Kirsten S Hall, Fredrik Mertens, Piero Picci, Sigbjørn Smeland, Ragnhild A Lothe

Journal: Neuro-oncology. 2013 Feb;15(2):135-47.

 

There are conflicting reports as to whether malignant peripheral nerve sheath tumor (MPNST) patients with neurofibromatosis type 1 (NF1) have worse prognosis than non-NF1 MPNST patients. Large clinical studies to address this problem are lacking due to the rareness of MPNST. We have ...

Last Updated: 21 Jan 2013

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A case of neurofibromatosis type 1 coinciding with bilateral pheochromocytomas, multiple gastrointestinal stromal tumors, and malignant peripheral nerve sheath tumor.
 

Author(s): Yuji Hataya, Yasato Komatsu, Keisuke Osaki, Yorihide Fukuda, Teruyuki Sato, Taisuke Morimoto

Journal: Intern. Med.. 2012 ;51(12):1531-6.

 

Neurofibromatosis type 1 (NF1) is associated with benign and malignant neoplasms, but the coincidence of abdominal neoplasms is rare. A 65-year-old woman with NF1 had episodes of nausea, tachycardia, hypertension, and loss of consciousness. Bilateral adrenal tumors were detected by ...

Last Updated: 25 Jun 2012

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Genetically engineered mouse models shed new light on the pathogenesis of neurofibromatosis type I-related neoplasms of the peripheral nervous system.
 

Author(s): Nicole M Brossier, Steven L Carroll

Journal: Brain Res. Bull.. 2012 May;88(1):58-71.

 

Neurofibromatosis type 1 (NF1), the most common genetic disorder affecting the human nervous system, is characterized by the development of multiple benign Schwann cell tumors in skin and large peripheral nerves. These neoplasms, which are termed dermal and plexiform neurofibromas ...

Last Updated: 7 May 2012

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Natural History Study of Patients With Neurofibromatosis Type I
 

Status: Recruiting

Condition Summary: Neurofibromatosis Type 1; Malignant Peripheral Nerve Sheath Tumor; Plexiform Neurofibroma; Optic Glioma; Neurofibroma

 

Last Updated: 21 May 2014

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Last Updated: 12 Aug 2014

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Study of Axitinib in Patients With Neurofibromatosis Type 2 and Progressive Vestibular Schwannomas
 

Status: Recruiting

Condition Summary: Neurofibromatosis Type 2; Vestibular Schwannomas

 

Last Updated: 1 May 2014

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