Peripheral type neurofibromatosis

Common Name(s)

Peripheral type neurofibromatosis

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Peripheral type neurofibromatosis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Peripheral type neurofibromatosis" returned 26 free, full-text research articles on human participants. First 3 results:

Diagnostic Accuracy of PET/CT-Guided Percutaneous Biopsies for Malignant Peripheral Nerve Sheath Tumors in Neurofibromatosis Type 1 Patients.
 

Author(s): Mehdi Brahmi, Philippe Thiesse, Dominique Ranchere, Thomas Mognetti, Stephane Pinson, Caroline Renard, Anne-Valérie Decouvelaere, Jean-Yves Blay, Patrick Combemale

Journal:

 

Malignant peripheral nerve sheath tumors (MPNST) are one of the most frequent causes of death in patients with neurofibromatosis type 1 (NF1). Early detection is crucial because complete surgical resection is the only curative treatment. It has been previously reported that an 18F-fluorodeoxyglucose ...

Last Updated: 8 Oct 2015

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Evaluation of copy number variation and gene expression in neurofibromatosis type-1-associated malignant peripheral nerve sheath tumours.
 

Author(s): Laura E Thomas, Jincy Winston, Ellie Rad, Matthew Mort, Kayleigh M Dodd, Andrew R Tee, Fionnuala McDyer, Stephen Moore, David N Cooper, Meena Upadhyaya

Journal:

 

Neurofibromatosis type-1 (NF1) is a complex neurogenetic disorder characterised by the development of benign and malignant tumours of the peripheral nerve sheath (MPNSTs). Whilst biallelic NF1 gene inactivation contributes to benign tumour formation, additional cellular changes in ...

Last Updated: 18 Apr 2015

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Methylated RASSF1A in malignant peripheral nerve sheath tumors identifies neurofibromatosis type 1 patients with inferior prognosis.
 

Author(s): Stine A Danielsen, Guro E Lind, Matthias Kolberg, Maren Høland, Bodil Bjerkehagen, Kirsten Sundby Hall, Eva van den Berg, Fredrik Mertens, Sigbjørn Smeland, Piero Picci, Ragnhild A Lothe

Journal: Neuro-oncology. 2015 Jan;17(1):63-9.

 

Malignant peripheral nerve sheath tumor (MPNST) is a rare and highly aggressive disease with no evidence of effect from adjuvant therapy. It is further associated with the hereditary syndrome neurofibromatosis type 1 (NF1). Silencing of the tumor suppressor gene RASSF1A through DNA ...

Last Updated: 24 Dec 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Peripheral type neurofibromatosis" returned 4 free, full-text review articles on human participants. First 3 results:

Survival meta-analyses for >1800 malignant peripheral nerve sheath tumor patients with and without neurofibromatosis type 1.
 

Author(s): Matthias Kolberg, Maren Høland, Trude H Agesen, Helge R Brekke, Knut Liestøl, Kirsten S Hall, Fredrik Mertens, Piero Picci, Sigbjørn Smeland, Ragnhild A Lothe

Journal: Neuro-oncology. 2013 Feb;15(2):135-47.

 

There are conflicting reports as to whether malignant peripheral nerve sheath tumor (MPNST) patients with neurofibromatosis type 1 (NF1) have worse prognosis than non-NF1 MPNST patients. Large clinical studies to address this problem are lacking due to the rareness of MPNST. We have ...

Last Updated: 21 Jan 2013

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A case of neurofibromatosis type 1 coinciding with bilateral pheochromocytomas, multiple gastrointestinal stromal tumors, and malignant peripheral nerve sheath tumor.
 

Author(s): Yuji Hataya, Yasato Komatsu, Keisuke Osaki, Yorihide Fukuda, Teruyuki Sato, Taisuke Morimoto

Journal: Intern. Med.. 2012 ;51(12):1531-6.

 

Neurofibromatosis type 1 (NF1) is associated with benign and malignant neoplasms, but the coincidence of abdominal neoplasms is rare. A 65-year-old woman with NF1 had episodes of nausea, tachycardia, hypertension, and loss of consciousness. Bilateral adrenal tumors were detected by ...

Last Updated: 25 Jun 2012

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Genetically engineered mouse models shed new light on the pathogenesis of neurofibromatosis type I-related neoplasms of the peripheral nervous system.
 

Author(s): Nicole M Brossier, Steven L Carroll

Journal: Brain Res. Bull.. 2012 May;88(1):58-71.

 

Neurofibromatosis type 1 (NF1), the most common genetic disorder affecting the human nervous system, is characterized by the development of multiple benign Schwann cell tumors in skin and large peripheral nerves. These neoplasms, which are termed dermal and plexiform neurofibromas ...

Last Updated: 7 May 2012

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Natural History Study of Patients With Neurofibromatosis Type I
 

Status: Recruiting

Condition Summary: Neurofibromatosis Type 1; Malignant Peripheral Nerve Sheath Tumor; Plexiform Neurofibroma; Optic Glioma; Neurofibroma

 

Last Updated: 11 May 2016

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Vaccine Therapy in Treating Patients With Malignant Peripheral Nerve Sheath Tumor That is Recurrent or Cannot Be Removed by Surgery
 

Status: Recruiting

Condition Summary: Metastatic Malignant Peripheral Nerve Sheath Tumor; Neurofibromatosis Type 1; Recurrent Malignant Peripheral Nerve Sheath Tumor

 

Last Updated: 17 Jun 2016

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Last Updated: 18 May 2016

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