Periodic Paralysis

Common Name(s)

Periodic Paralysis

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Periodic Paralysis" for support, advocacy or research.

Periodic Paralysis Association

To provide convenient access to science-based information to help better understand and manage the periodic paralyses. To stimulate interaction between the periodic paralysis community and various professional disciplines that may be able to bring light to this complex and often misunderstood collection of disorders. To provide the tools and a forum for open discussion of the diverse issues associated with these disorders. To promote an increasing level of awareness of these disorders, leading to increased research, improved management guidelines, improved diagnostic protocols, and ultimately, their prevention and cure

Last Updated: 23 Jun 2015

View Details
Logo
Periodic Paralysis International

Our Mission statement is to disseminate timely, medically accurate and useful information, to provide supportive services, and to encourage research which enhances the quality of life for people with the skeletal muscle ion channelopathies classified as the periodic paralyses.

Last Updated: 12 Feb 2013

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Periodic Paralysis" for support, advocacy or research.

Periodic Paralysis Association

To provide convenient access to science-based information to help better understand and manage the periodic paralyses. To stimulate interaction between the periodic paralysis community and various professional disciplines that may be able to bring light to this complex and often misunderstood collection of disorders. To provide the tools and a forum for open discussion of the diverse issues associated with these disorders. To promote an increasing level of awareness of these disorders, leading to increased research, improved management guidelines, improved diagnostic protocols, and ultimately, their prevention and cure

http://www.periodicparalysis.org

Last Updated: 23 Jun 2015

View Details
Logo
Periodic Paralysis International

Our Mission statement is to disseminate timely, medically accurate and useful information, to provide supportive services, and to encourage research which enhances the quality of life for people with the skeletal muscle ion channelopathies classified as the periodic paralyses.

http://hkpp.org

Last Updated: 12 Feb 2013

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Periodic Paralysis" returned 183 free, full-text research articles on human participants. First 3 results:

Gitelman's syndrome presenting with hypocalcemic tetany and hypokalemic periodic paralysis.
 

Author(s): Kunal Gandhi, Dharmendra Prasad, Vinay Malhotra, Dhananjai Agrawal

Journal: Saudi J Kidney Dis Transpl. ;27(5):1026-1028.

 

Gitelman's syndrome is an autosomal recessive renal tubular disorder characterized by hypomagnesemia, hypokalemia, hypocalciuria, and metabolic alkalosis. Hypocalcemic tetany as a presentation of Gitelman's syndrome has rarely been reported in literature. We report a rare case of ...

Last Updated: 18 Oct 2016

Go To URL
Thyrotoxic hypokalemic periodic paralysis in a Turkish patient presenting with a U wave on ECG.
 

Author(s): Emre Gezer, Banu Şarer Yurekli, Gokçen Unal Kocabas

Journal: Hormones (Athens). 2016 Jul;15(3):464-465.

 

Last Updated: 10 Jul 2016

Go To URL
Randomized, placebo-controlled trials of dichlorphenamide in periodic paralysis.
 

Author(s): Valeria A Sansone, James Burge, Michael P McDermott, Patty C Smith, Barbara Herr, Rabi Tawil, Shree Pandya, John Kissel, Emma Ciafaloni, Perry Shieh, Jeffrey W Ralph, Antony Amato, Steve C Cannon, Jaya Trivedi, Richard Barohn, Brian Crum, Hiroshi Mitsumoto, Alan Pestronk, Giovanni Meola, Robin Conwit, Michael G Hanna, Robert C Griggs,

Journal: Neurology. 2016 Apr;86(15):1408-16.

 

To determine the short-term and long-term effects of dichlorphenamide (DCP) on attack frequency and quality of life in hyperkalemic (HYP) and hypokalemic (HOP) periodic paralysis.

Last Updated: 11 May 2016

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Periodic Paralysis" returned 9 free, full-text review articles on human participants. First 3 results:

Extracellular potassium homeostasis: insights from hypokalemic periodic paralysis.
 

Author(s): Chih-Jen Cheng, Elizabeth Kuo, Chou-Long Huang

Journal: Semin. Nephrol.. 2013 May;33(3):237-47.

 

Extracellular potassium makes up only about 2% of the total body's potassium store. The majority of the body potassium is distributed in the intracellular space, of which about 80% is in skeletal muscle. Movement of potassium in and out of skeletal muscle thus plays a pivotal role ...

Last Updated: 19 Aug 2013

Go To URL
Mechanism of thyrotoxic periodic paralysis.
 

Author(s): Shih-Hua Lin, Chou-Long Huang

Journal: J. Am. Soc. Nephrol.. 2012 Jun;23(6):985-8.

 

The pathogenesis of thyrotoxic periodic paralysis has long been thought related to increased Na(+)-K(+) ATPase activity stimulated by thyroid hormone and/or hyperadrenergic activity and hyperinsulinemia. This mechanism alone, however, cannot adequately explain how hypokalemia occurs ...

Last Updated: 1 Jun 2012

Go To URL
Muscle channelopathies: does the predicted channel gating pore offer new treatment insights for hypokalaemic periodic paralysis?
 

Author(s): E Matthews, M G Hanna

Journal: J. Physiol. (Lond.). 2010 Jun;588(Pt 11):1879-86.

 

Hypokalaemic periodic paralysis (hypoPP) is the archetypal skeletal muscle channelopathy caused by dysfunction of one of two sarcolemmal ion channels, either the sodium channel Nav1.4 or the calcium channel Cav1.1. Clinically, hypoPP is characterised by episodes of often severe flaccid ...

Last Updated: 2 Jun 2010

Go To URL
 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 18 Jan 2017

Go to URL