Pemphigus vulgaris

Common Name(s)

Pemphigus vulgaris

Pemphigus vulgaris is an autoimmune disorder that involves blistering of the skin and mucous membranes. It occurs almost exclusively in middle-aged or older people. Many cases begin with blisters in the mouth, followed by skin blisters that may come and go. In most cases, the exact cause of pemphigus vulgaris is unknown.  It has rarely been observed in multiple members of the same family. Treatment is aimed at reducing symptoms and preventing complications. Severe cases are treated similarly to severe burns.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Pemphigus vulgaris" for support, advocacy or research.

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International Pemphigus and Pemphigoid Foundation

The IPPF provides direct access to innovative and effective support that promotes the very best health care, improves quality of life, stimulates community resources, advocates for favorable government policies, accelerates the pace of scientific discovery and is the world’s best source of information on pemphigus and pemphigoid. We are compassionate in understanding, tireless in service, and relentless in advocating. One person at a time, we make a difference, building a community of care and hope.

Last Updated: 8 Mar 2013

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Pemphigus vulgaris" for support, advocacy or research.

Logo
International Pemphigus and Pemphigoid Foundation

The IPPF provides direct access to innovative and effective support that promotes the very best health care, improves quality of life, stimulates community resources, advocates for favorable government policies, accelerates the pace of scientific discovery and is the world’s best source of information on pemphigus and pemphigoid. We are compassionate in understanding, tireless in service, and relentless in advocating. One person at a time, we make a difference, building a community of care and hope.

http://www.pemphigus.org/

Last Updated: 8 Mar 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Pemphigus vulgaris" returned 279 free, full-text research articles on human participants. First 3 results:

Oral Pemphigus Vulgaris In A Pediatric Patient.
 

Author(s): Manas Bajpai, Nilesh Pardhe, Betina Chandolia

Journal: J Ayub Med Coll Abbottabad. ;28(3):636.

 

Last Updated: 31 Dec 1969

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Pemphigus Vulgaris Persistently Localized to the Nose with Local and Systemic Response to Topical Steroids.
 

Author(s): Connie Zhang, Ilana Goldscheider, Thomas Ruzicka, Miklós Sárdy

Journal: Acta Derm. Venereol.. 2017 Oct;97(9):1136-1137.

 

is missing (Short communication).

Last Updated: 31 Dec 1969

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Pemphigus Vulgaris and Pemphigus Foliaceus: Differences in Epidemiology and Mortality.
 

Author(s): Khalaf Kridin, Shira Zelber-Sagi, Reuven Bergman

Journal: Acta Derm. Venereol.. 2017 Oct;97(9):1095-1099.

 

Little is known about differences in epidemiological features and prognosis between pemphigus vulgaris (PV) and pemphigus foliaceus (PF). The objective of this study was to compare PV and PF patients regarding ethnic variations and mortality rates. Mortality of PV and PF patients ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Pemphigus vulgaris" returned 16 free, full-text review articles on human participants. First 3 results:

A reciprocal HLA-Disease Association in Rheumatoid Arthritis and Pemphigus Vulgaris.
 

Author(s): Vincent Van Drongelen, Joseph Holoshitz

Journal:

 

Human leukocyte antigens (HLA) have been extensively studied as being antigen presenting receptors, but many aspects of their function remain elusive, especially their association with various autoimmune diseases. Here we discuss an illustrative case of the reciprocal relationship ...

Last Updated: 31 Dec 1969

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Management of Pemphigus Vulgaris.
 

Author(s): Mimansa Cholera, Nita Chainani-Wu

Journal: Adv Ther. 2016 Jun;33(6):910-58.

 

Pemphigus vulgaris (PV) is a chronic, autoimmune, vesiculobullous disease. As a result of the relative rarity of PV, published randomized controlled trials (RCTs) are limited, which makes it difficult to evaluate the efficacy of different treatment regimens in this disease. This also ...

Last Updated: 31 Dec 1969

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The dual nature of interleukin-10 in pemphigus vulgaris.
 

Author(s): Michael Jeffrey Cho, Christoph T Ellebrecht, Aimee S Payne

Journal: Cytokine. 2015 Jun;73(2):335-41.

 

The immunomodulatory cytokine interleukin-10 (IL-10) plays beneficial but also potentially detrimental roles in inflammation, infection, and autoimmunity. Recent studies suggest a regulatory role for IL-10-expressing B cells in the autoimmune blistering disease pemphigus vulgaris. ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Serum IL-21 Levels in Patients With Pemphigus Vulgaris
 

Status: Not yet recruiting

Condition Summary: Pemphigus Vulgaris

 

Last Updated: 4 Jun 2017

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Last Updated: 19 Jan 2018

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A Study of PRN1008 in Adult Patients With Pemphigus Vulgaris
 

Status: Recruiting

Condition Summary: Pemphigus Vulgaris

 

Last Updated: 5 Dec 2017

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