Pemphigus vulgaris

Common Name(s)

Pemphigus vulgaris

Pemphigus vulgaris is an autoimmune disorder that involves blistering of the skin and mucous membranes. It occurs almost exclusively in middle-aged or older people. Many cases begin with blisters in the mouth, followed by skin blisters that may come and go. In most cases, the exact cause of pemphigus vulgaris is unknown.  It has rarely been observed in multiple members of the same family. Treatment is aimed at reducing symptoms and preventing complications. Severe cases are treated similarly to severe burns.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Pemphigus vulgaris" for support, advocacy or research.

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International Pemphigus and Pemphigoid Foundation

The IPPF provides direct access to innovative and effective support that promotes the very best health care, improves quality of life, stimulates community resources, advocates for favorable government policies, accelerates the pace of scientific discovery and is the world’s best source of information on pemphigus and pemphigoid. We are compassionate in understanding, tireless in service, and relentless in advocating. One person at a time, we make a difference, building a community of care and hope.

Last Updated: 8 Mar 2013

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Pemphigus vulgaris" for support, advocacy or research.

Logo
International Pemphigus and Pemphigoid Foundation

The IPPF provides direct access to innovative and effective support that promotes the very best health care, improves quality of life, stimulates community resources, advocates for favorable government policies, accelerates the pace of scientific discovery and is the world’s best source of information on pemphigus and pemphigoid. We are compassionate in understanding, tireless in service, and relentless in advocating. One person at a time, we make a difference, building a community of care and hope.

http://www.pemphigus.org/

Last Updated: 8 Mar 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Pemphigus vulgaris" returned 256 free, full-text research articles on human participants. First 3 results:

Long-Term Remissions in Recalcitrant Pemphigus Vulgaris.
 

Author(s): A Razzaque Ahmed, Srini Kaveri, Zachary Spigelman

Journal: N. Engl. J. Med.. 2015 Dec;373(27):2693-4.

 

Last Updated: 31 Dec 2015

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Mucosal-dominant pemphigus vulgaris in a captopril-taking woman with angioedema.
 

Author(s): Justyna Gornowicz-Porowska, Marian Dmochowski, Pawel Pietkiewicz, Monika Bowszyc-Dmochowska

Journal: An Bras Dermatol. ;90(5):748-51.

 

We describe a 39-year-old woman with an apparent captopril-induced, contact mucosal-dominant pemphigus vulgaris and angioedema, who took captopril during a bout of arterial hypertension. This exposure suggests that captopril and pathophysiology of angioedema stimulated the development ...

Last Updated: 12 Nov 2015

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Dapsone in the treatment of pemphigus vulgaris: adverse effects and its importance as a corticosteroid sparing agent.
 

Author(s): Maria Victória Quaresma, Fred Bernardes Filho, Janaína Hezel, Murilo Calvo Peretti, Bernard Kawa Kac, Luna Azulay-Abulafia

Journal: An Bras Dermatol. ;90(3 Suppl 1):51-4.

 

Pemphigus vulgaris is an autoimmune disease characterized by suprabasal blisters with acantholysis, which has a fatal course in a large number of untreated patients. Systemic corticosteroid therapy is considered first-line therapy. Adjuvant treatment with the goal of sparing corticosteroids ...

Last Updated: 28 Aug 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Pemphigus vulgaris" returned 15 free, full-text review articles on human participants. First 3 results:

[Cutaneous pemphigus vulgaris. A case report].
 

Author(s): Cristina Bello, Luis Mondaca-Cornejo, Cristian Navarrete-Dechent, Sergio González

Journal: Rev Med Chil. 2013 Apr;141(4):525-30.

 

Pemphigus is an autoimmune bullous disease that involves skin and mucous membranes caused by autoantibodies against antigens on the surface of keratinocytes. We report a 30-year-old mole presenting with a five months history of pruriginous alopecic and crusted lesions in the scalp, ...

Last Updated: 31 Jul 2013

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Evidence-based treatments for pemphigus vulgaris, pemphigus foliaceus, and bullous pemphigoid: a systematic review.
 

Author(s): Sanjay Singh

Journal: Indian J Dermatol Venereol Leprol. ;77(4):456-69.

 

Pemphigus, bullous pemphigoid, and epidermolysis bullosa acquisita are autoimmune diseases of skin associated with considerable morbidity and sometimes mortality. There is no cure for these diseases.

Last Updated: 5 Jul 2011

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Refractory pemphigus vulgaris associated with herpes infection: case report and review.
 

Author(s): Maria Luiza Figueiredo Braga Brandão, Nurimar C Fernandes, Danielle Pereira de Oliveira Batista, Norma Santos

Journal: Rev. Inst. Med. Trop. Sao Paulo. ;53(2):113-7.

 

Pemphigus vulgaris (PV) is an autoimmune disease characterized by blistering of the skin and mucosa, which develops due to the interaction between predisposing genetic and environmental factors. Infections caused by members of the Herpesviridae family have been suggested as a possible ...

Last Updated: 3 May 2011

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

A Study of PRN1008 in Adult Patients With Pemphigus Vulgaris
 

Status: Recruiting

Condition Summary: Pemphigus Vulgaris

 

Last Updated: 11 Apr 2016

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Last Updated: 4 May 2016

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Autoimmune Blistering Diseases Study
 

Status: Recruiting

Condition Summary: Pemphigus Vulgaris; Pemphigus Foliaceus; Bullous Pemphigoid

 

Last Updated: 25 Apr 2016

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