Pemphigus vulgaris

Common Name(s)

Pemphigus vulgaris

Pemphigus vulgaris is an autoimmune disorder that involves blistering of the skin and mucous membranes. It occurs almost exclusively in middle-aged or older people. Many cases begin with blisters in the mouth, followed by skin blisters that may come and go. In most cases, the exact cause of pemphigus vulgaris is unknown.  It has rarely been observed in multiple members of the same family. Treatment is aimed at reducing symptoms and preventing complications. Severe cases are treated similarly to severe burns.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Pemphigus vulgaris" for support, advocacy or research.

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International Pemphigus and Pemphigoid Foundation

The IPPF provides direct access to innovative and effective support that promotes the very best health care, improves quality of life, stimulates community resources, advocates for favorable government policies, accelerates the pace of scientific discovery and is the world’s best source of information on pemphigus and pemphigoid. We are compassionate in understanding, tireless in service, and relentless in advocating. One person at a time, we make a difference, building a community of care and hope.

Last Updated: 8 Mar 2013

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Pemphigus vulgaris" for support, advocacy or research.

Logo
International Pemphigus and Pemphigoid Foundation

The IPPF provides direct access to innovative and effective support that promotes the very best health care, improves quality of life, stimulates community resources, advocates for favorable government policies, accelerates the pace of scientific discovery and is the world’s best source of information on pemphigus and pemphigoid. We are compassionate in understanding, tireless in service, and relentless in advocating. One person at a time, we make a difference, building a community of care and hope.

http://www.pemphigus.org/

Last Updated: 8 Mar 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Pemphigus vulgaris" returned 184 free, full-text research articles on human participants. First 3 results:

[Pemphigus vulgaris with severe eye involvement].
 

Author(s): Hend Chaabane, Dalinda El Euch, Ines Zaraa, Mourad Mokni, Amel Ben Osman Dhahri

Journal: Tunis Med. 2014 Dec;92(12):760-2.

 

Last Updated: 17 Apr 2015

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Oral pemphigus vulgaris after Chilean earthquake.
 

Author(s): César Rivera, Bernardo Venegas

Journal:

 

Last Updated: 25 Nov 2014

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The value of trichoscopy in the differential diagnosis of scalp lesions in pemphigus vulgaris and pemphigus foliaceus.
 

Author(s): Marta Sar-Pomian, Marta Kurzeja, Lidia Rudnicka, Malgorzata Olszewska

Journal: An Bras Dermatol. ;89(6):1007-12.

 

Trichoscopy is becoming increasingly popular in diagnosing hair and scalp diseases. Scalp involvement in pemphigus is common. The scalp may be the first or only site of clinical manifestation of the disease.

Last Updated: 12 Nov 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Pemphigus vulgaris" returned 15 free, full-text review articles on human participants. First 3 results:

[Cutaneous pemphigus vulgaris. A case report].
 

Author(s): Cristina Bello, Luis Mondaca-Cornejo, Cristian Navarrete-Dechent, Sergio González

Journal: Rev Med Chil. 2013 Apr;141(4):525-30.

 

Pemphigus is an autoimmune bullous disease that involves skin and mucous membranes caused by autoantibodies against antigens on the surface of keratinocytes. We report a 30-year-old mole presenting with a five months history of pruriginous alopecic and crusted lesions in the scalp, ...

Last Updated: 31 Jul 2013

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Evidence-based treatments for pemphigus vulgaris, pemphigus foliaceus, and bullous pemphigoid: a systematic review.
 

Author(s): Sanjay Singh

Journal: Indian J Dermatol Venereol Leprol. ;77(4):456-69.

 

Pemphigus, bullous pemphigoid, and epidermolysis bullosa acquisita are autoimmune diseases of skin associated with considerable morbidity and sometimes mortality. There is no cure for these diseases.

Last Updated: 5 Jul 2011

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Refractory pemphigus vulgaris associated with herpes infection: case report and review.
 

Author(s): Maria Luiza Figueiredo Braga Brandão, Nurimar C Fernandes, Danielle Pereira de Oliveira Batista, Norma Santos

Journal: Rev. Inst. Med. Trop. Sao Paulo. ;53(2):113-7.

 

Pemphigus vulgaris (PV) is an autoimmune disease characterized by blistering of the skin and mucosa, which develops due to the interaction between predisposing genetic and environmental factors. Infections caused by members of the Herpesviridae family have been suggested as a possible ...

Last Updated: 3 May 2011

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Study of Efficacy and Safety of VAY736 in Patients With Pemphigus Vulgaris
 

Status: Recruiting

Condition Summary: Pemphigus Vulgaris

 

Last Updated: 11 Aug 2015

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Last Updated: 1 Sep 2015

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Efficacy and Safety of Ofatumumab in Treatment of Pemphigus Vulgaris
 

Status: Recruiting

Condition Summary: Pemphigus

 

Last Updated: 23 Jul 2015

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