Pemphigus foliaceus

Common Name(s)

Pemphigus foliaceus

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Pemphigus foliaceus" for support, advocacy or research.

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International Pemphigus and Pemphigoid Foundation

The IPPF provides direct access to innovative and effective support that promotes the very best health care, improves quality of life, stimulates community resources, advocates for favorable government policies, accelerates the pace of scientific discovery and is the world’s best source of information on pemphigus and pemphigoid. We are compassionate in understanding, tireless in service, and relentless in advocating. One person at a time, we make a difference, building a community of care and hope.

Last Updated: 8 Mar 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Pemphigus foliaceus" for support, advocacy or research.

Logo
International Pemphigus and Pemphigoid Foundation

The IPPF provides direct access to innovative and effective support that promotes the very best health care, improves quality of life, stimulates community resources, advocates for favorable government policies, accelerates the pace of scientific discovery and is the world’s best source of information on pemphigus and pemphigoid. We are compassionate in understanding, tireless in service, and relentless in advocating. One person at a time, we make a difference, building a community of care and hope.

http://www.pemphigus.org/

Last Updated: 8 Mar 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Pemphigus foliaceus" returned 116 free, full-text research articles on human participants. First 3 results:

Pemphigus foliaceus as a differential diagnosis in vesicobullous lesions.
 

Author(s): Louise de Almeida Ferreira Fonseca, Célia Antônia Xavier de Moraes Alves, Ivan Aprahamian, Clóvis Antônio Lopes Pinto

Journal: Einstein (Sao Paulo). ;15(2):220-222.

 

Given the challenge of clinical diagnosis of bullous skin lesions, this report aimed to discuss the histological changes, the presentation and clinical reasoning for diagnosis of these lesions. At the same time, the importance of the pathology was reviewed to identify these clinical ...

Last Updated: 2 Aug 2017

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Non-pathogenic pemphigus foliaceus (PF) IgG acts synergistically with a directly pathogenic PF IgG to increase blistering by p38MAPK-dependent desmoglein 1 clustering.
 

Author(s): Kenji Yoshida, Ken Ishii, Atsushi Shimizu, Mariko Yokouchi, Masayuki Amagai, Ken Shiraishi, Yuji Shirakata, John R Stanley, Akira Ishiko

Journal: J. Dermatol. Sci.. 2017 Mar;85(3):197-207.

 

Pemphigus foliaceus (PF) is an autoimmune blistering disease caused by autoantibodies (Abs) against desmoglein 1 (Dsg1). PF sera contain polyclonal Abs which are heterogeneous mixture of both pathogenic and non-pathogenic Abs, as shown by isolation of monoclonal Abs (mAbs).

Last Updated: 27 Dec 2016

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A 3'UTR polymorphism marks differential KLRG1 mRNA levels through disruption of a miR-584-5p binding site and associates with pemphigus foliaceus susceptibility.
 

Author(s): Gabriel A Cipolla, Jong Kook Park, Liana A de Oliveira, Sara Cristina Lobo-Alves, Rodrigo C de Almeida, Ticiana D J Farias, Débora de S Lemos, Danielle Malheiros, Robert M Lavker, Maria Luiza Petzl-Erler

Journal: Biochim. Biophys. Acta. 2016 10;1859(10):1306-13.

 

Genetic variations mapping to 3' untranslated regions (3'UTRs) may overlap with microRNA (miRNA) binding sites, therefore potentially interfering with translation inhibition or messenger RNA (mRNA) degradation. The aim of this study was to investigate whether single nucleotide polymorphisms ...

Last Updated: 22 Aug 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Pemphigus foliaceus" returned 7 free, full-text review articles on human participants. First 3 results:

Update on fogo selvagem, an endemic form of pemphigus foliaceus.
 

Author(s): Valeria Aoki, Evandro A Rivitti, Luis A Diaz,

Journal: J. Dermatol.. 2015 Jan;42(1):18-26.

 

Pemphigus are organ-specific autoimmune diseases, where autoantibodies (mainly immunoglobulin [Ig]G) directed against epidermal targets (glycoproteins of the desmosomal core) are detected. Endemic pemphigus foliaceus or fogo selvagem (FS) is one of the variants of pemphigus foliaceus ...

Last Updated: 6 Jan 2015

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Evidence-based treatments for pemphigus vulgaris, pemphigus foliaceus, and bullous pemphigoid: a systematic review.
 

Author(s): Sanjay Singh

Journal: Indian J Dermatol Venereol Leprol. ;77(4):456-69.

 

Pemphigus, bullous pemphigoid, and epidermolysis bullosa acquisita are autoimmune diseases of skin associated with considerable morbidity and sometimes mortality. There is no cure for these diseases.

Last Updated: 5 Jul 2011

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Diagnosis and clinical features of pemphigus foliaceus.
 

Author(s): Kirk A James, Donna A Culton, Luis A Diaz

Journal: Dermatol Clin. 2011 Jul;29(3):405-12, viii.

 

Pemphigus foliaceus is an acquired autoimmune blistering disease in which the body's immune system produces IgG autoantibodies that target the intercellular adhesion glycoprotein desmoglein-1, which is principally expressed in the granular layer of the epidermis, resulting in the ...

Last Updated: 24 May 2011

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Polyclonal Regulatory T Cells (PolyTregs) for Pemphigus
 

Status: Recruiting

Condition Summary: Pemphigus Foliaceus; Pemphigus Vulgaris

 

Last Updated: 22 Sep 2017

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A Safety Study of SYNT001 in Subjects With Pemphigus (Vulgaris or Foliaceus)
 

Status: Recruiting

Condition Summary: Pemphigus; Pemphigus Vulgaris; Pemphigus Foliaceus

 

Last Updated: 28 Sep 2017

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Autoimmune Blistering Diseases Study
 

Status: Recruiting

Condition Summary: Pemphigus Vulgaris; Pemphigus Foliaceus; Bullous Pemphigoid

 

Last Updated: 10 Nov 2016

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