Pemphigus

Common Name(s)

Pemphigus

Pemphigus is a group of rare autoimmune diseases that cause blistering of the skin and mucous membranes (mouth, nose, throat, eyes, and genitals).  This condition can occur at any age, but often strikes people in middle or older age. It is more common in people of Middle Eastern or Jewish descent than in other races and cultures. Pemphigus is a chronic disease which is best controlled by early diagnosis and treatment.  Treatment includes steroids to reduce inflammation, drugs that suppress the immune system response and antibiotics to treat associated infections.

There are three main types of pemphigus:

Pemphigus vulgaris Pemphigus foliaceus  Paraneoplastic pemphigus
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Pemphigus" for support, advocacy or research.

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International Pemphigus and Pemphigoid Foundation

The IPPF provides direct access to innovative and effective support that promotes the very best health care, improves quality of life, stimulates community resources, advocates for favorable government policies, accelerates the pace of scientific discovery and is the world’s best source of information on pemphigus and pemphigoid. We are compassionate in understanding, tireless in service, and relentless in advocating. One person at a time, we make a difference, building a community of care and hope.

Last Updated: 8 Mar 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Pemphigus" for support, advocacy or research.

Logo
International Pemphigus and Pemphigoid Foundation

The IPPF provides direct access to innovative and effective support that promotes the very best health care, improves quality of life, stimulates community resources, advocates for favorable government policies, accelerates the pace of scientific discovery and is the world’s best source of information on pemphigus and pemphigoid. We are compassionate in understanding, tireless in service, and relentless in advocating. One person at a time, we make a difference, building a community of care and hope.

http://www.pemphigus.org/

Last Updated: 8 Mar 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Pemphigus" returned 671 free, full-text research articles on human participants. First 3 results:

Th1/Th17-Related Cytokines and Chemokines and Their Implications in the Pathogenesis of Pemphigus Vulgaris.
 

Author(s): Rodolfo Pessato Timoteo, Marcos Vinicius da Silva, Camila Botelho Miguel, Djalma Alexandre Alves Silva, Jonatas Da Silva Catarino, Virmondes Rodrigues Junior, Helioswilton Sales-Campos, Carlo Jose Freire Oliveira

Journal: Mediators Inflamm.. 2017 ;2017():7151285.

 

Pemphigus vulgaris (PV) is an autoimmune disease characterized by the presence of IgG autoantibodies against desmoglein-3. Despite the variety of findings, the chemokine and cytokine profiles that characterize the immune response in the disease are still poorly explored. Thus, 20 ...

Last Updated: 21 Mar 2017

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Paraneoplastic pemphigus associated with chronic lymphocytic leukemia: A case report.
 

Author(s): Qu Jiang, Bin Hong Zhang

Journal: Medicine (Baltimore). 2017 Feb;96(8):e6184.

 

Paraneoplastic pemphigus (PNP) is an autoimmune syndrome associated with neoplasms. The treatment approach principally includes suppressing the immunity, but its therapeutic effect is not satisfying.

Last Updated: 22 Feb 2017

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Salivary Samples for the Diagnosis of Pemphigus vulgaris Using the BIOCHIP Approach: a Pilot Study.
 

Author(s): Irene Russo, Andrea Saponeri, Anna Michelotto, Mauro Alaibac

Journal: In Vivo. 2017 01;31(1):97-99.

 

Pemphigus vulgaris (PV) is a rare autoimmune intraepithelial blistering skin disease characterized by the presence of circulating autoantibodies against desmoglein 3 (DSG3) and desmoglein 1 (DSG1), resulting in loss of the normal epithelial cell-to-cell adhesion, through a process ...

Last Updated: 8 Jan 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Pemphigus" returned 48 free, full-text review articles on human participants. First 3 results:

Juvenile IgA pemphigus: A case report and review of literature.
 

Author(s): Kanagala Chowdary Neethu, Raghavendra Rao, C Balachandran, Sathish Pai

Journal: Indian J Dermatol Venereol Leprol. ;82(4):439-42.

 

Last Updated: 9 Jun 2016

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Paraneoplastic pemphigus associated with follicular dendritic cell sarcoma: report of a case and review of literature.
 

Author(s): Zheng Su, Gaojie Liu, Jianping Liu, Tingfeng Fang, Yunjie Zeng, Huayao Zhang, Shanglin Yang, Yang Wang, Junmin Zhang, Jinxing Wei, Yingru Li, Youfeng Guo

Journal:

 

Follicular dendritic cell sarcoma (FDCS) is a rare tumor associated with paraneoplastic pemphigus. It is Blame drenchs auxiliary cell tumor which is derived from the peripheral lymphoid tissues. Throughout the world, several patients of paraneoplastic pemphigus associated follicular ...

Last Updated: 1 Jan 2016

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Pemphigus and pregnancy. Analysis and summary of case reports over 49 years.
 

Author(s): Lin Lin, Xin Zeng, Qianming Chen

Journal: Saudi Med J. 2015 Sep;36(9):1033-8.

 

Pemphigus is a group of immune-mediated bullous disorders, which often cause fragile blisters and extensive lesions of the skin or mucous membranes, such as in the mouth. This disease could be life-threatening in some cases. During pregnancy, its condition will become more complicated ...

Last Updated: 31 Aug 2015

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Serum IL-21 Levels in Patients With Pemphigus Vulgaris
 

Status: Not yet recruiting

Condition Summary: Pemphigus Vulgaris

 

Last Updated: 4 Jun 2017

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A Study of PRN1008 in Adult Patients With Pemphigus Vulgaris
 

Status: Recruiting

Condition Summary: Pemphigus Vulgaris

 

Last Updated: 28 Feb 2017

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