Pemphigus

Common Name(s)

Pemphigus

Pemphigus is a group of rare autoimmune diseases that cause blistering of the skin and mucous membranes (mouth, nose, throat, eyes, and genitals).  This condition can occur at any age, but often strikes people in middle or older age. It is more common in people of Middle Eastern or Jewish descent than in other races and cultures. Pemphigus is a chronic disease which is best controlled by early diagnosis and treatment.  Treatment includes steroids to reduce inflammation, drugs that suppress the immune system response and antibiotics to treat associated infections.

There are three main types of pemphigus:

Pemphigus vulgaris Pemphigus foliaceus  Paraneoplastic pemphigus
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Pemphigus" for support, advocacy or research.

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International Pemphigus and Pemphigoid Foundation

The IPPF provides direct access to innovative and effective support that promotes the very best health care, improves quality of life, stimulates community resources, advocates for favorable government policies, accelerates the pace of scientific discovery and is the world’s best source of information on pemphigus and pemphigoid. We are compassionate in understanding, tireless in service, and relentless in advocating. One person at a time, we make a difference, building a community of care and hope.

Last Updated: 8 Mar 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Pemphigus" for support, advocacy or research.

Logo
International Pemphigus and Pemphigoid Foundation

The IPPF provides direct access to innovative and effective support that promotes the very best health care, improves quality of life, stimulates community resources, advocates for favorable government policies, accelerates the pace of scientific discovery and is the world’s best source of information on pemphigus and pemphigoid. We are compassionate in understanding, tireless in service, and relentless in advocating. One person at a time, we make a difference, building a community of care and hope.

http://www.pemphigus.org/

Last Updated: 8 Mar 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Pemphigus" returned 703 free, full-text research articles on human participants. First 3 results:

Evaluation of anti-desmoglein-1 and anti-desmoglein-3 autoantibody titers in pemphigus patients at the time of the initial diagnosis and after clinical remission.
 

Author(s): Irene Russo, Francesco Paolo De Siena, Andrea Saponeri, Mauro Alaibac

Journal: Medicine (Baltimore). 2017 Nov;96(46):e8801.

 

It has been suggested that anti-desmoglein autoantibody titers could be helpful in follow-up and therapeutic management of pemphigus patients. However, there is no consensus regarding the relationship between anti-desmoglein autoantibody titers and clinical activity of pemphigus.The ...

Last Updated: 31 Dec 1969

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Biologic therapy-induced pemphigus.
 

Author(s): Marina Zoega Hayashida, Jhonatan Rafael Siqueira Pinheiro, Milvia Maria Simões E Silva Enokihara, Mônica Ribeiro de Azevedo Vasconcellos

Journal: An Bras Dermatol. ;92(4):591-593.

 

Last Updated: 31 Dec 1969

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Refractory pemphigus foliaceus associated with herpesvirus infection: case report.
 

Author(s): Nurimar C Fernandes, Heloisa Rampinelli, Leandro Magalhães de Souza, Maria Angélica A M Guimarães

Journal: Rev. Inst. Med. Trop. Sao Paulo. 2017 ;59():e41.

 

Pemphigus foliaceus (PF) is an autoimmune disease characterized by blistering of the skin. Infections caused by members of the herpesviridae family have been suggested as a possible triggering factor for pemphigus vulgaris (PV), but not for PF. The present study aimed to investigate ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Pemphigus" returned 53 free, full-text review articles on human participants. First 3 results:

A reciprocal HLA-Disease Association in Rheumatoid Arthritis and Pemphigus Vulgaris.
 

Author(s): Vincent Van Drongelen, Joseph Holoshitz

Journal:

 

Human leukocyte antigens (HLA) have been extensively studied as being antigen presenting receptors, but many aspects of their function remain elusive, especially their association with various autoimmune diseases. Here we discuss an illustrative case of the reciprocal relationship ...

Last Updated: 31 Dec 1969

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Management of Pemphigus Vulgaris.
 

Author(s): Mimansa Cholera, Nita Chainani-Wu

Journal: Adv Ther. 2016 Jun;33(6):910-58.

 

Pemphigus vulgaris (PV) is a chronic, autoimmune, vesiculobullous disease. As a result of the relative rarity of PV, published randomized controlled trials (RCTs) are limited, which makes it difficult to evaluate the efficacy of different treatment regimens in this disease. This also ...

Last Updated: 31 Dec 1969

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Juvenile IgA pemphigus: A case report and review of literature.
 

Author(s): Kanagala Chowdary Neethu, Raghavendra Rao, C Balachandran, Sathish Pai

Journal: Indian J Dermatol Venereol Leprol. ;82(4):439-42.

 

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Serum IL-21 Levels in Patients With Pemphigus Vulgaris
 

Status: Not yet recruiting

Condition Summary: Pemphigus Vulgaris

 

Last Updated: 4 Jun 2017

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Last Updated: 19 Jan 2018

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A Study of PRN1008 in Adult Patients With Pemphigus Vulgaris
 

Status: Recruiting

Condition Summary: Pemphigus Vulgaris

 

Last Updated: 5 Dec 2017

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