Pediatric ulcerative colitis

Common Name(s)

Pediatric ulcerative colitis

Pediatric ulcerative colitis (UC) is a form of inflammatory bowel disease that occurs in children. UC causes redness and swelling (inflammation) inside the large intestine (colon). This inflammation is what causes the major symptoms of UC, which are stomach pain or cramping, rectal bleeding, and diarrhea. Other symptoms may include low energy (fatigue), decreased appetite, joint pain, low blood count (anemia), or liver problems. Children with UC often lose weight or have trouble gaining weight. The exact cause of UC is unknown, but researchers believe it is due to a combination of genetic and environmental reasons. Some cases of UC may be due to the body’s immune system attacking normal cells in the colon (autoimmune disease). UC can occur at any age, but approximately 20% of UC cases occur under the age of 20 in the United States.

Your child’s doctor can diagnose UC by gathering your child’s medical history and performing a physical exam. They may also order blood tests to look for signs of inflammation, x-rays to look at the intestines, and perform stool sample analysis. In addition, your child’s doctor may use a viewing tube to examine the intestines and even collect a small piece of the colon (biopsy). The tube can be inserted through the mouth (called an endoscopy) or inserted through the anus (called a colonoscopy). Although there is no cure for UC, there are options to help manage the symptoms of the condition. There are medications that can reduce the inflammation in the colon and also medications that can reduce the immune response in the body. If the UC is severe, surgery may be needed. Talk to your child's doctor or specialist about the most current treatment options. Support groups are also good source of information and will help connect you with other families.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Pediatric ulcerative colitis" for support, advocacy or research.

Crohn's & Colitis Foundation of America, Inc.

CCFA's mission is to cure Crohn's disease and ulcerative colitis and to improve the quality of life of children and adults affected by these diseases.

Last Updated: 8 Apr 2014

View Details
Logo
Digestive Disease National Coalition

The Digestive Disease National Coalition (DDNC) has provided national leadership on behalf of patient organizations, professional societies, and industry interested in the full spectrum of digestive disorders.

Last Updated: 29 Apr 2014

View Details
Pull-thru Network, Inc.

The Pull-thru Network is a volunteer-based organization dedicated to providing education, information, support and advocacy for those individuals, and the families of those individuals, who are affected by any congenital anorectal, colorectal or urogenital disorder and any of the variety of related diagnoses.

Last Updated: 8 Nov 2012

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Pediatric ulcerative colitis" for support, advocacy or research.

Crohn's & Colitis Foundation of America, Inc.

CCFA's mission is to cure Crohn's disease and ulcerative colitis and to improve the quality of life of children and adults affected by these diseases.

http://www.ccfa.org

Last Updated: 8 Apr 2014

View Details
Logo
Digestive Disease National Coalition

The Digestive Disease National Coalition (DDNC) has provided national leadership on behalf of patient organizations, professional societies, and industry interested in the full spectrum of digestive disorders.

http://ddnc.org/

Last Updated: 29 Apr 2014

View Details
Pull-thru Network, Inc.

The Pull-thru Network is a volunteer-based organization dedicated to providing education, information, support and advocacy for those individuals, and the families of those individuals, who are affected by any congenital anorectal, colorectal or urogenital disorder and any of the variety of related diagnoses.

http://www.PullthruNetwork.org

Last Updated: 8 Nov 2012

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Pediatric ulcerative colitis" returned 18 free, full-text research articles on human participants. First 3 results:

Characteristics of pediatric ulcerative colitis in Saudi Arabia: a multicenter national study.
 

Author(s): Khalid AlSaleem, Mohammad Issa El Mouzan, Omar I Saadah, Bader AlSaleem, Abdulrahman Al-Hussaini, Mohammed Hassosa, Al-Mehaidib Ali, Mohammed Othman Banemai, Hana Halaby, Mohammed El Edreesi

Journal: Ann Saudi Med. ;35(1):19-22.

 

Despite the extensive reporting of pediatric ulcerative colitis (UC) from industrialized developed countries, reports from developing countries are limited to small-case series from single centers. The objective of our large multicenter study was to determine the clinical, laboratory, ...

Last Updated: 6 Jul 2015

Go To URL
Serial fecal microbiota transplantation alters mucosal gene expression in pediatric ulcerative colitis.
 

Author(s): Richard Kellermayer, Dorottya Nagy-Szakal, R Alan Harris, Ruth Ann Luna, Milena Pitashny, Deborah Schady, Sabina A V Mir, Monica E Lopez, Mark A Gilger, John Belmont, Emily B Hollister, James Versalovic

Journal: Am. J. Gastroenterol.. 2015 Apr;110(4):604-6.

 

Last Updated: 9 Apr 2015

Go To URL
A microRNA signature in pediatric ulcerative colitis: deregulation of the miR-4284/CXCL5 pathway in the intestinal epithelium.
 

Author(s): Georgios Koukos, Christos Polytarchou, Jess L Kaplan, Angelos Oikonomopoulos, David Ziring, Daniel W Hommes, Renaisa Wahed, Efi Kokkotou, Charalabos Pothoulakis, Harland S Winter, Dimitrios Iliopoulos

Journal: Inflamm. Bowel Dis.. 2015 May;21(5):996-1005.

 

Twenty to 25% of the patients with inflammatory bowel disease (IBD) present the disease before the age of 18 to 20, with worse extent and severity, compared with adult-onset IBD. We sought to identify the differential expression of microRNAs in pediatric ulcerative colitis (UC) and ...

Last Updated: 18 Apr 2015

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Pediatric ulcerative colitis" returned 0 free, full-text review articles on human participants.

 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Mission is Remission®: How Can a Disease Self-management Website Change Care?
 

Status: Not yet recruiting

Condition Summary: Pediatric Crohn's Disease; Pediatric Ulcerative Colitis

 

Last Updated: 23 Feb 2016

Go to URL
Curcumin in Pediatric Ulcerative Colitis
 

Status: Not yet recruiting

Condition Summary: Ulcerative Colitis

 

Last Updated: 13 Apr 2016

Go to URL
Use of a Novel Diet (UC DIET) for Treatment of Mild to Moderate Active Pediatric Ulcerative Colitis
 

Status: Recruiting

Condition Summary: Ulcerative Colitis (UC)

 

Last Updated: 10 Aug 2016

Go to URL