Pediatric T-cell leukemia

Common Name(s)

Pediatric T-cell leukemia

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Pediatric T-cell leukemia" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Pediatric T-cell leukemia" returned 28 free, full-text research articles on human participants. First 3 results:

The activating STAT5B N642H mutation is a common abnormality in pediatric T-cell acute lymphoblastic leukemia and confers a higher risk of relapse.
 

Author(s): Obul R Bandapalli, Stephanie Schuessele, Joachim B Kunz, Tobias Rausch, Adrian M St├╝tz, Noa Tal, Ifat Geron, Nava Gershman, Shai Izraeli, Juliane Eilers, Nina Vaezipour, Renate Kirschner-Schwabe, Jana Hof, Arend von Stackelberg, Martin Schrappe, Martin Stanulla, Martin Zimmermann, Rolf Koehler, Smadar Avigad, Rupert Handgretinger, Viktoras Frismantas, Jean Pierre Bourquin, Beat Bornhauser, Jan O Korbel, Martina U Muckenthaler, Andreas E Kulozik

Journal: Haematologica. 2014 Oct;99(10):e188-92.

 

Last Updated: 1 Oct 2014

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Pediatric posttransplant relapsed/refractory B-precursor acute lymphoblastic leukemia shows durable remission by therapy with the T-cell engaging bispecific antibody blinatumomab.
 

Author(s): Patrick Schlegel, Peter Lang, Gerhard Zugmaier, Martin Ebinger, Hermann Kreyenberg, Kai-Erik Witte, Judith Feucht, Matthias Pfeiffer, Heiko-Manuel Teltschik, Christina Kyzirakos, Tobias Feuchtinger, Rupert Handgretinger

Journal: Haematologica. 2014 Jul;99(7):1212-9.

 

We report on posttransplant relapsed pediatric patients with B-precursor acute lymphoblastic leukemia with no further standard of care therapy who were treated with the T-cell engaging CD19/CD3-bispecific single-chain antibody construct blinatumomab on a compassionate use basis. Blast ...

Last Updated: 2 Jul 2014

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MYCN is a novel oncogenic target in pediatric T-cell acute lymphoblastic leukemia.
 

Author(s): Annalisa Astolfi, Francesca Vendemini, Milena Urbini, Fraia Melchionda, Riccardo Masetti, Monica Franzoni, Virginia Libri, Salvatore Serravalle, Marco Togni, Giuseppina Paone, Luca Montemurro, Daniela Bressanin, Francesca Chiarini, Alberto M Martelli, Roberto Tonelli, Andrea Pession

Journal: Oncotarget. 2014 Jan;5(1):120-30.

 

MYCN is an oncogene frequently overexpressed in pediatric solid tumors whereas few evidences suggest his involvement in the pathogenesis of haematologic malignancies. Here we show that MYCN is overexpressed in a relevant proportion (40 to 50%) of adult and pediatric T-cell acute lymphoblastic ...

Last Updated: 17 Mar 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Pediatric T-cell leukemia" returned 0 free, full-text review articles on human participants.

 
 
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Symptoms, Diagnosis, and Treatment

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There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Re-Induction Therapy for Relapsed Pediatric T-Cell Acute Lymphoblastic Leukemia or Lymphoma
 

Status: Not yet recruiting

Condition Summary: Acute Lymphoblastic Leukemia; Lymphoma, Non-Hodgkin's; Leukemia, T-Cell; Leukemia, B-Cell

 

Last Updated: 5 Aug 2015

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Last Updated: 23 Nov 2014

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Last Updated: 6 Aug 2015

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