Patent ductus arteriosus

Common Name(s)

Patent ductus arteriosus

Patent ductus arteriosus (PDA) is a common heart defect that occurs when the ductus arteriosis does not close shortly after birth. The ductus arteriosis is a fetal artery connecting the aorta and the pulmonary artery. When the artery is not closed properly, it acts as a detour by not sending all the blood to the lungs (fetal blood obtains oxygen from the placenta). After birth, oxygen poor blood needs to go to the lungs to obtain oxygen. If the ductus arteriosis does not close, it can cause both the lungs and the heart to work too hard. PDA is sometimes found with other heart defects or in certain genetic conditions such as Down syndrome. PDA appears to be more common in girls.

Usually PDA is diagnosed in infancy but if it is small, symptoms may only appear in childhood. Severity of symptoms depends on the size and whether other heart defects are also present. Symptoms may include poor feeding or sweating while feeding, shortness of breath, tiring easily, fast pulse and poor growth. The causes of PDA are likely a combination of genetics and environment. Risk factors include premature birth, being born at a high altitude, a rubella infection during pregnancy, or a family history of certain genetic conditions.

A heart murmur is usually heard in infancy, but may be missed in a premature baby. The diagnosis will be confirmed using X-rays and an electrocardiogram (EKG). Other tests may check for other possible heart defects. In premature babies, the opening may close on its own even after the first few days, so the PDA may just be watched. Treatment options include medication and surgery, and may not be necessary. Outlook is excellent if PDA occurs without any associated birth defects. Talk to your baby’s cardiologist about treatment and management options. If the PDA is part of a syndrome or runs in your family, talk to a genetic counselor. Support groups are a good source of information and can connect you to other families affected by PDA.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Patent ductus arteriosus" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Patent ductus arteriosus" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Patent ductus arteriosus" returned 470 free, full-text research articles on human participants. First 3 results:

When to Close Patent Ductus Arteriosus, Authors Reply.
 

Author(s): Nandkishor Kabra

Journal: Indian Pediatr. 2016 Jan;53(1):78.

 

Last Updated: 4 Feb 2016

Go To URL
When to Close Patent Ductus arteriosus, The Ideal Time and Rationale.
 

Author(s): Abdul Razak, N Karthik Nagesh

Journal: Indian Pediatr. 2016 Jan;53(1):78.

 

Last Updated: 4 Feb 2016

Go To URL
Patent Ductus Arteriosus - A Complex Problem in Need of a Solid Conceptual Foundation.
 

Author(s): Carl H Backes, Charles V Smith

Journal: Circ. J.. 2016 ;80(3):601-2.

 

Last Updated: 25 Feb 2016

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Patent ductus arteriosus" returned 36 free, full-text review articles on human participants. First 3 results:

Chorioamnionitis and Patent Ductus Arteriosus: A Systematic Review and Meta-Analysis.
 

Author(s): Hye Won Park, Yong-Sung Choi, Kyo Sun Kim, Soo-Nyung Kim

Journal:

 

Chorioamnionitis has recently been reported as a risk factor for various neonatal diseases, including cerebral palsy, bronchopulmonary dysplasia, and necrotizing enterocolitis, but its effect on patent ductus arteriosus (PDA) is unclear. We performed a systematic review and meta-analysis ...

Last Updated: 17 Sep 2015

Go To URL
Is thoracoscopic patent ductus arteriosus closure superior to conventional surgery?
 

Author(s): Tomasz Stankowski, Sleiman Sebastian Aboul-Hassan, Jakub Marczak, Romuald Cichon

Journal: Interact Cardiovasc Thorac Surg. 2015 Oct;21(4):532-8.

 

A best evidence topic in cardiac surgery was written according to a structured protocol. The question addressed was whether thoracoscopic patent ductus arteriosus (PDA) closure is superior to conventional surgery. Altogether 821 papers were found using the reported search, 11 of which ...

Last Updated: 22 Sep 2015

Go To URL
Platelet Counts and Patent Ductus Arteriosus in Preterm Infants: A Systematic Review and Meta-Analysis.
 

Author(s): Sorina R Simon, Lieke van Zogchel, Maria Pilar Bas-Suárez, Giacomo Cavallaro, Ronald I Clyman, Eduardo Villamor

Journal: Neonatology. 2015 ;108(2):143-51.

 

Several cohort studies have shown an association between low platelet counts in the first day(s) of life and patent ductus arteriosus (PDA) in preterm infants. However, these results have not been confirmed by other studies.

Last Updated: 17 Aug 2015

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Early Treatment Versus Delayed Conservative Treatment of the Patent Ductus Arteriosus
 

Status: Recruiting

Condition Summary: Patent Ductus Arteriosus; Surgery; Necrotizing Enterocolitis; Intestinal Perforation

 

Last Updated: 1 Dec 2015

Go to URL
Treating the Resistant Patent Ductus Arteriosus (PDA)
 

Status: Not yet recruiting

Condition Summary: Patent Ductus Arteriosus

 

Last Updated: 14 Feb 2008

Go to URL
Early Ibuprofen Treatment of Patent Ductus Arteriosus (PDA) in Premature Infants (TRIOCAPI)
 

Status: Recruiting

Condition Summary: Patent Ductus Arteriosus

 

Last Updated: 7 Mar 2016

Go to URL