Paroxysmal ventricular fibrillation

Common Name(s)

Paroxysmal ventricular fibrillation, Paroxysmal familial ventricular fibrillation, Idiopathic Ventricular Fibrillation (IVF), Ventricular fibrillation, idiopathic

Ventricular fibrillation (VF) is said to cause more than 300,000 sudden deaths each year in the US alone. In approximately 5 to 12% of cases, there are no demonstrable cardiac or noncardiac causes to account for the episode, which is therefore classified as idiopathic ventricular fibrillation (IVF). Patients with a distinct form of VF called Brugada syndrome (see {601144}) present with a characteristic electrocardiographic pattern, with right bundle branch block (RBBB) and elevation of ST segment in leads V1 to V3 and may account for 40 to 60% of all IVF cases (review by {3:Chen et al., 1998}). Mutations in the SCN5A gene were identified in patients with Brugada syndrome-1 ({601144}). Genetic Heterogeneity of Paroxysmal Familial Ventricular Fibrillation Another familial form of VF (VF2; {612956}) is caused by mutation in the DPP6 gene ({126141}) on chromosome 7q26.
 

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Condition Specific Organizations

Following organizations serve the condition "Paroxysmal ventricular fibrillation" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Paroxysmal ventricular fibrillation" returned 13 free, full-text research articles on human participants. First 3 results:

Left ventricular stiffness estimated by diastolic wall strain is associated with paroxysmal atrial fibrillation in structurally normal hearts.
 

Author(s): Shunsuke Uetake, Mitsunori Maruyama, Teppei Yamamoto, Katsuhito Kato, Yasushi Miyauchi, Yoshihiko Seino, Wataru Shimizu

Journal: Clin Cardiol. 2016 Dec;39(12):728-732.

 

Left ventricular (LV) diastolic dysfunction depends on an impaired relaxation and stiffness. Abnormal LV relaxation contributes to the development of atrial fibrillation (AF), but the role of LV stiffness in AF remains unclear.

Last Updated: 31 Dec 1969

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Left ventricular diastolic dysfunction is associated with atrial remodeling and risk or presence of stroke in patients with paroxysmal atrial fibrillation.
 

Author(s): Tae-Hoon Kim, Chi Young Shim, Jae Hyung Park, Chung Mo Nam, Jae-Sun Uhm, Boyoung Joung, Moon-Hyoung Lee, Hui-Nam Pak

Journal: J Cardiol. 2016 08;68(2):104-9.

 

Although the degree of electroanatomical remodeling of the left atrium (LA) is influenced by left ventricular (LV) diastolic function, clinical implications of estimated LV filling pressure (E/Em) are limited in patients with atrial fibrillation (AF). We hypothesized that increased ...

Last Updated: 31 Dec 1969

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Left ventricular native T1 time and the risk of atrial fibrillation recurrence after pulmonary vein isolation in patients with paroxysmal atrial fibrillation.
 

Author(s): Shingo Kato, Murilo Foppa, S├ębastien Roujol, Tamer Basha, Sophie Berg, Kraig V Kissinger, Beth Goddu, Warren J Manning, Reza Nezafat

Journal: Int. J. Cardiol.. 2016 Jan;203():848-54.

 

Native T1 mapping has emerged as a noninvasive non-contrast magnetic resonance imaging (MRI) method to assess for diffuse myocardial fibrosis. However, LV native T1 time in AF patients and its clinical relevance are unclear.

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Paroxysmal ventricular fibrillation" returned 0 free, full-text review articles on human participants.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

DOuble SEquential External Defibrillation for Refractory VF
 

Status: Not yet recruiting

Condition Summary: Ventricular Fibrillation

 

Last Updated: 14 Aug 2017

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Prognostic Value of Ventricular Fibrillation Spectral Analysis in Sudden Cardiac Death
 

Status: Recruiting

Condition Summary: Sudden Cardiac Death; Ventricular Fibrillation; Reperfusion Injury

 

Last Updated: 13 Aug 2017

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Cardioverter Defibrillator Replacement With Induction of Ventricular Fibrillation and Defibrillation Testing
 

Status: Recruiting

Condition Summary: Defibrillation Capacity of Defibrilators After Replacement

 

Last Updated: 18 Oct 2017

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