Paraplegia

Common Name(s)

Paraplegia

Description for this condition is not yet available.
 

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Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Paraplegia" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Paraplegia" returned 754 free, full-text research articles on human participants. First 3 results:

Effect of exoskeletal joint constraint and passive resistance on metabolic energy expenditure: Implications for walking in paraplegia.
 

Author(s): Sarah R Chang, Rudi Kobetic, Ronald J Triolo

Journal:

 

An important consideration in the design of a practical system to restore walking in individuals with spinal cord injury is to minimize metabolic energy demand on the user. In this study, the effects of exoskeletal constraints on metabolic energy expenditure were evaluated in able-bodied ...

Last Updated: 31 Dec 1969

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mutation in three siblings with familial hereditary spastic paraplegia.
 

Author(s): Leila Dardour, Filip Roelens, Valerie Race, Erika Souche, Maureen Holvoet, Koen Devriendt

Journal:

 

Troyer syndrome (MIM#275900) is an autosomal recessive form of complicated hereditary spastic paraplegia. It is characterized by progressive lower extremity spasticity and weakness, dysarthria, distal amyotrophy, developmental delay, short stature, and subtle skeletal abnormalities. ...

Last Updated: 31 Dec 1969

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Characterization of kinesin switch I mutations that cause hereditary spastic paraplegia.
 

Author(s): Scott Jennings, Madeline Chenevert, Liqiong Liu, Madhusoodanan Mottamal, Edward J Wojcik, Thomas M Huckaba

Journal:

 

Kif5A is a neuronally-enriched isoform of the Kinesin-1 family of cellular transport motors. 23 separate mutations in the motor domain of Kif5A have been identified in patients with the complicated form of hereditary spastic paraplegia (HSP). We performed in vitro assays on dimeric ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Paraplegia" returned 42 free, full-text review articles on human participants. First 3 results:

Hereditary spastic paraplegia from 1880 to 2017: an historical review.
 

Author(s): Ingrid Faber, Eduardo Rafael Pereira, Alberto R M Martinez, Marcondes França, Hélio Afonso Ghizoni Teive

Journal: Arq Neuropsiquiatr. 2017 Nov;75(11):813-818.

 

The authors have constructed a brief timeline of major clinical research related to hereditary spastic paraplegia (HSP). This timeline summarizes the evolution of HSP research, from the first clinical descriptions by Adolf von Strümpell in 1880 to the present day, with the transformation ...

Last Updated: 31 Dec 1969

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Hereditary spastic paraplegia due to a novel mutation of the REEP1 gene: Case report and literature review.
 

Author(s): Sébastien Richard, Julie Lavie, Guillaume Banneau, Nathalie Voirand, Karine Lavandier, Marc Debouverie

Journal: Medicine (Baltimore). 2017 Jan;96(3):e5911.

 

Hereditary spastic paraplegia (HSP) is a heterogeneous group of diseases little known in clinical practice due to its low prevalence, slow progression, and difficult diagnosis. This results in an underestimation of HSP leading to belated diagnosis and management. In depth diagnosis ...

Last Updated: 31 Dec 1969

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Posterior-only vertebral column resection for revision surgery in post-laminectomy rotokyphoscoliosis associated with late-onset paraplegia: A case report and literature review.
 

Author(s): Youping Tao, Jigong Wu, Huasong Ma

Journal: Medicine (Baltimore). 2017 Jan;96(1):e5690.

 

Severe post-laminectomy spinal deformity associated with late-onset paraplegia is a complex and rare disorder. Little is known about revision surgery in post-laminectomy rotokyphoscoliosis associated with late-onset paraplegia treated by the single stage posterior-only vertebral column ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Disease Natural History and Biomarkers of SPG3A, SPG4A, and SPG31
 

Status: Recruiting

Condition Summary: Hereditary Spastic Paraplegia

 

Last Updated: 13 Feb 2018

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Performance Developement of Patients With Paraplegia During First Rehabilitation
 

Status: Recruiting

Condition Summary: Physical Activity

 

Last Updated: 19 Jan 2018

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The Pre-SPG4 Study
 

Status: Recruiting

Condition Summary: Hereditary Spastic Paraplegia; Hereditary, Spastic Paraplegia, Autosomal Dominant

 

Last Updated: 2 Jul 2017

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