Paraplegia

Common Name(s)

Paraplegia

Description for this condition is not yet available.
 

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Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Paraplegia" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Paraplegia" returned 724 free, full-text research articles on human participants. First 3 results:

NT5C2 novel splicing variant expands the phenotypic spectrum of Spastic Paraplegia (SPG45): case report of a new member of thin corpus callosum SPG-Subgroup.
 

Author(s): Mahmoud F Elsaid, Khalid Ibrahim, Nader Chalhoub, Ahmed Elsotouhy, Noora El Mudehki, Alice Abdel Aleem

Journal:

 

Hereditary Spastic Paraplegia (HSP) is a genetically heterogeneous group of neurodegenerative diseases. Thin Corpus Callosum (TCC) associated HSP is a distinguished subgroup of complex forms. Purines and pyrimidine, the basic DNA and RNA components, are regulating the cell metabolism, ...

Last Updated: 22 Mar 2017

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Management of acute spontaneous thoracic spinal epidural hematoma causing paraplegia.
 

Author(s): Fahrudin Alić, Hakija Bečulić, Aldin Jusić, Rasim Skomorac, Mirza Moranjkić, Lejla Hrvat, Lejla Tandir

Journal: Med Glas (Zenica). 2017 Feb;14(1):106-110.

 

Aim To emphasize the importance of early recognition, diagnostic processing and emergent surgical treatment of spontaneous spinal epidural hematoma (SSEH). Methods A 39-year-old female presented with sudden onset of severe pain between the shoulder blades followed by paraparesis and ...

Last Updated: 6 Feb 2017

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ATPase-deficient mitochondrial inner membrane protein ATAD3A disturbs mitochondrial dynamics in dominant hereditary spastic paraplegia.
 

Author(s): Helen M Cooper, Yang Yang, Emil Ylikallio, Rafil Khairullin, Rosa Woldegebriel, Kai-Lan Lin, Liliya Euro, Eino Palin, Alexander Wolf, Ras Trokovic, Pirjo Isohanni, Seppo Kaakkola, Mari Auranen, Tuula Lönnqvist, Sjoerd Wanrooij, Henna Tyynismaa

Journal: Hum. Mol. Genet.. 2017 Apr;26(8):1432-1443.

 

De novo mutations in ATAD3A (ATPase family AAA-domain containing protein 3A) were recently found to cause a neurological syndrome with developmental delay, hypotonia, spasticity, optic atrophy, axonal neuropathy, and hypertrophic cardiomyopathy. Using whole-exome sequencing, we identified ...

Last Updated: 3 Feb 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Paraplegia" returned 39 free, full-text review articles on human participants. First 3 results:

Hereditary spastic paraplegia due to a novel mutation of the REEP1 gene: Case report and literature review.
 

Author(s): Sébastien Richard, Julie Lavie, Guillaume Banneau, Nathalie Voirand, Karine Lavandier, Marc Debouverie

Journal: Medicine (Baltimore). 2017 Jan;96(3):e5911.

 

Hereditary spastic paraplegia (HSP) is a heterogeneous group of diseases little known in clinical practice due to its low prevalence, slow progression, and difficult diagnosis. This results in an underestimation of HSP leading to belated diagnosis and management. In depth diagnosis ...

Last Updated: 18 Jan 2017

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Posterior-only vertebral column resection for revision surgery in post-laminectomy rotokyphoscoliosis associated with late-onset paraplegia: A case report and literature review.
 

Author(s): Youping Tao, Jigong Wu, Huasong Ma

Journal: Medicine (Baltimore). 2017 Jan;96(1):e5690.

 

Severe post-laminectomy spinal deformity associated with late-onset paraplegia is a complex and rare disorder. Little is known about revision surgery in post-laminectomy rotokyphoscoliosis associated with late-onset paraplegia treated by the single stage posterior-only vertebral column ...

Last Updated: 10 Jan 2017

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Tau missorting and spastin-induced microtubule disruption in neurodegeneration: Alzheimer Disease and Hereditary Spastic Paraplegia.
 

Author(s): Hans Zempel, Eva-Maria Mandelkow

Journal:

 

In Alzheimer Disease (AD), the mechanistic connection of the two major pathological hallmarks, namely deposition of Amyloid-beta (Aβ) in the form of extracellular plaques, and the pathological changes of the intracellular protein Tau (such as phosphorylation, missorting, aggregation), ...

Last Updated: 22 Dec 2015

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Safety and Tolerance of Local Heat Application in the Paralyzed Area of Patients With Complete Paraplegia
 

Status: Recruiting

Condition Summary: Perfusion; Complications

 

Last Updated: 25 Jan 2017

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Disease Natural History and Biomarkers of SPG3A, SPG4A, and SPG31
 

Status: Recruiting

Condition Summary: Hereditary Spastic Paraplegia

 

Last Updated: 30 Jun 2017

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The Pre-SPG4 Study
 

Status: Recruiting

Condition Summary: Hereditary Spastic Paraplegia; Hereditary, Spastic Paraplegia, Autosomal Dominant

 

Last Updated: 2 Jul 2017

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