Panuveitis

Common Name(s)

Panuveitis

Panuveitis is a serious disease that causes inflammation of the eye. “Uveitis” refers to general inflammation of a portion of the eye, usually just the front of the eye. In panuveitis, however, both the front and the back of the eye are affected. The affected region is known as the uveal tract, which is composed of the iris, the choroid, and the ciliary body. The iris is the colored back of your eye that controls the size of your pupil. The choroid is the inner lining of the eye that contains blood vessels. The ciliary body produces fluid to keep your eye moist. All of these structures are important for vision, and inflammation of these components can cause visual problems.

The cause of panuveitis is generally unknown, but there are some links to other diseases such as syphilis, sarcoidosis, toxoplasmosis, and tuberculosis. Some other possible causes may include infections, tumors, bruises, and toxins in the eyes. The main symptoms of panuveitis are eye pain, blurred vision, vision loss, light sensitivity, redness of the eyes, and seeing spots. Because panuveitis can spread rapidly through the eye, it is important to seek medical attention as soon as any symptoms occur to prevent permanent damage or blindness. Panuveitis is usually diagnosed through an eye exam, and treatment typically includes medications to suppress the inflammation, such as local steroids. Support groups are available for more information and resources.

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Advocacy and Support Organizations

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Panuveitis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Panuveitis" returned 46 free, full-text research articles on human participants. First 3 results:

Corticosteroid-Related Adverse Events Systematically Increase with Corticosteroid Dose in Noninfectious Intermediate, Posterior, or Panuveitis: Post Hoc Analyses from the VISUAL-1 and VISUAL-2 Trials.
 

Author(s): Eric B Suhler, Jennifer E Thorne, Manish Mittal, Keith A Betts, Samir Tari, Anne Camez, Yanjun Bao, Avani Joshi

Journal: Ophthalmology. 2017 12;124(12):1799-1807.

 

Chronic use of corticosteroids for the treatment of uveitis has been linked with drug-associated toxicity and adverse events (AEs). This study examines the association between corticosteroid dosage and incidence rates of corticosteroid-related AEs.

Last Updated: 31 Dec 1969

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Association Between Long-Lasting Intravitreous Fluocinolone Acetonide Implant vs Systemic Anti-inflammatory Therapy and Visual Acuity at 7 Years Among Patients With Intermediate, Posterior, or Panuveitis.
 

Author(s): , John H Kempen, Michael M Altaweel, Janet T Holbrook, Elizabeth A Sugar, Jennifer E Thorne, Douglas A Jabs

Journal: JAMA. 2017 May;317(19):1993-2005.

 

A randomized clinical trial comparing fluocinolone acetonide implant vs systemic corticosteroids and immunosuppression for treatment of severe noninfectious intermediate, posterior, and panuveitides did not result in a significant difference in visual acuity at 2 and 4.5 years; longer-term ...

Last Updated: 31 Dec 1969

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Effect of Adalimumab on Visual Functioning in Patients With Noninfectious Intermediate Uveitis, Posterior Uveitis, and Panuveitis in the VISUAL-1 and VISUAL-2 Trials.
 

Author(s): John Sheppard, Avani Joshi, Keith A Betts, Stacie Hudgens, Samir Tari, Naijun Chen, Martha Skup, Andrew D Dick

Journal: JAMA Ophthalmol. 2017 Jun;135(6):511-518.

 

Adalimumab was recently approved for the treatment of noninfectious intermediate uveitis, posterior uveitis, and panuveitis.

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Panuveitis" returned 4 free, full-text review articles on human participants. First 3 results:

[Panuveitis with oral and genital ulcer misdiagnosed as Behcet's disease: two cases report and literature review].
 

Author(s): Y Wang, L Yang, Z L Zhang

Journal: Beijing Da Xue Xue Bao. 2016 10;48(5):910-914.

 

Here we reported two patients who presented with panuveitis and were transferred from ophthalmologists to rheumatologists, for both the patients had oral and genital ulcers. They were misdiagnosed with Behcet's disease at first glance. Two young males presented with acute uveitis ...

Last Updated: 31 Dec 1969

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SEVERE PANUVEITIS, RETINAL VASCULITIS, AND OPTIC DISK GRANULOMA SECONDARY TO SARCOIDOSIS.
 

Author(s): Michael Patterson, Chris S Bergstrom, W Lloyd Clark, Hans E Grossniklaus, John F Payne

Journal: Retin Cases Brief Rep. 2016 ;10(4):341-4.

 

To report a case of panuveitis, retinal vasculitis, and optic disk granuloma due to sarcoidosis.

Last Updated: 31 Dec 1969

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Heterogeneity of primary outcome measures used in clinical trials of treatments for intermediate, posterior, and panuveitis.
 

Author(s): Alastair K Denniston, Gary N Holland, Andrej Kidess, Robert B Nussenblatt, Annabelle A Okada, James T Rosenbaum, Andrew D Dick

Journal:

 

Uveitis describes a heterogeneous group of conditions characterized by intraocular inflammation. Since most of the sight-threatening forms of uveitis are individually rare, there has been an increasing tendency for clinical trials to group distinct uveitis syndromes together despite ...

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 16 May 2018

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