Panuveitis

Common Name(s)

Panuveitis

Panuveitis is a serious disease that causes inflammation of the eye. “Uveitis” refers to general inflammation of a portion of the eye, usually just the front of the eye. In panuveitis, however, both the front and the back of the eye are affected. The affected region is known as the uveal tract, which is composed of the iris, the choroid, and the ciliary body. The iris is the colored back of your eye that controls the size of your pupil. The choroid is the inner lining of the eye that contains blood vessels. The ciliary body produces fluid to keep your eye moist. All of these structures are important for vision, and inflammation of these components can cause visual problems.

The cause of panuveitis is generally unknown, but there are some links to other diseases such as syphilis, sarcoidosis, toxoplasmosis, and tuberculosis. Some other possible causes may include infections, tumors, bruises, and toxins in the eyes. The main symptoms of panuveitis are eye pain, blurred vision, vision loss, light sensitivity, redness of the eyes, and seeing spots. Because panuveitis can spread rapidly through the eye, it is important to seek medical attention as soon as any symptoms occur to prevent permanent damage or blindness. Panuveitis is usually diagnosed through an eye exam, and treatment typically includes medications to suppress the inflammation, such as local steroids. Support groups are available for more information and resources.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Panuveitis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Panuveitis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Panuveitis" returned 40 free, full-text research articles on human participants. First 3 results:

Choroidal Vascularity Index (CVI)--A Novel Optical Coherence Tomography Parameter for Monitoring Patients with Panuveitis?
 

Author(s): Rupesh Agrawal, Mohammed Salman, Kara-Anne Tan, Michael Karampelas, Dawn A Sim, Pearse A Keane, Carlos Pavesio

Journal:

 

To compute choroidal vascularity index (CVI) using an image binarization tool on enhanced depth imaging (EDI)-optical coherence tomography (OCT) scans as a non-invasive optical tool to monitor progression in panuveitis and to investigate the utility of volumetric data from EDI-OCT ...

Last Updated: 12 Jan 2016

Go To URL
Risk of Ocular Complications in Patients with Noninfectious Intermediate Uveitis, Posterior Uveitis, or Panuveitis.
 

Author(s): Andrew D Dick, Namita Tundia, Rachael Sorg, Chen Zhao, Jingdong Chao, Avani Joshi, Martha Skup

Journal: Ophthalmology. 2016 Mar;123(3):655-62.

 

Noninfectious uveitis results in vision loss and ocular complications without adequate treatment. We compared the risk of developing ocular complications between patients with noninfectious intermediate uveitis, posterior uveitis, or panuveitis (NIIPPU) and matched controls.

Last Updated: 23 Feb 2016

Go To URL
Factors Predicting Visual Acuity Outcome in Intermediate, Posterior, and Panuveitis: The Multicenter Uveitis Steroid Treatment (MUST) Trial.
 

Author(s): John H Kempen, Mark L Van Natta, Michael M Altaweel, James P Dunn, Douglas A Jabs, Susan L Lightman, Jennifer E Thorne, Janet T Holbrook,

Journal: Am. J. Ophthalmol.. 2015 Dec;160(6):1133-1141.e9.

 

To identify factors associated with best-corrected visual acuity (BCVA) presentation and 2-year outcome in 479 intermediate, posterior, and panuveitic eyes.

Last Updated: 17 Nov 2015

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Panuveitis" returned 2 free, full-text review articles on human participants. First 3 results:

Heterogeneity of primary outcome measures used in clinical trials of treatments for intermediate, posterior, and panuveitis.
 

Author(s): Alastair K Denniston, Gary N Holland, Andrej Kidess, Robert B Nussenblatt, Annabelle A Okada, James T Rosenbaum, Andrew D Dick

Journal:

 

Uveitis describes a heterogeneous group of conditions characterized by intraocular inflammation. Since most of the sight-threatening forms of uveitis are individually rare, there has been an increasing tendency for clinical trials to group distinct uveitis syndromes together despite ...

Last Updated: 19 Aug 2015

Go To URL
Current approach in the diagnosis and management of panuveitis.
 

Author(s): Reema Bansal, Vishali Gupta, Amod Gupta

Journal: Indian J Ophthalmol. ;58(1):45-54.

 

Panuveitis is a generalized inflammation of not only the whole of the uveal tract but also involves the retina and vitreous humor. It differs from other anatomical sites of inflammation in terms of causes as well as distribution. The common causes of panuveitis in our population are ...

Last Updated: 23 Dec 2009

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Safety,Tolerability and Efficacy of Intravitreal LFG316 in Patients With Active Non-infectious Intermediate-, posterior-or Panuveitis ,
 

Status: Recruiting

Condition Summary: Non-infectious Intermediate Uveitis; Non-infectious Posterior Uveitis; Non-infectious Panuveitis

 

Last Updated: 26 Oct 2016

Go to URL

Last Updated: 8 Nov 2016

Go to URL
Ocular Sarcoidosis Open Label Trial of ACTHAR Gel
 

Status: Recruiting

Condition Summary: Ocular Sarcoidosis; Panuveitis; Anterior Uveitis

 

Last Updated: 25 Oct 2016

Go to URL