Pancreatic cancer

Common Name(s)

Pancreatic cancer

Pancreatic cancer occurs when cells of the pancreas grow abnormally to form a tumor. The pancreas is a gland that normally makes juices that help break down food and produces insulin and other hormones. Pancreatic cancer usually doesn't cause symptoms right away, but can cause yellowing of the skin and eyes, pain in the abdomen and back, weight loss, and fatigue. Some risk factors for developing pancreatic cancer include smoking, long-term diabetes, chronic pancreatitis, and certain hereditary disorders. Because pancreatic cancer is often found late and it spreads quickly, it can be hard to treat. Possible treatments include surgery, radiation, and chemotherapy.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Pancreatic cancer" for support, advocacy or research.

Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

Last Updated: 29 Jul 2015

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Pancreatic Cancer Action Network

The Pancreatic Cancer Action Network is a nationwide network of people dedicated to working together to advance research, support patients and create hope for those affected by pancreatic cancer.

Last Updated: 20 Feb 2013

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The Lustgarten Foundation

The Lustgarten Foundation is committed to advancing the scientific and medical research related to the diagnosis, treatment, cure and prevention of pancreatic cancer.

Last Updated: 20 Feb 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Pancreatic cancer" for support, advocacy or research.

Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

http://www.CancerHopeNetwork.org

Last Updated: 29 Jul 2015

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Pancreatic Cancer Action Network

The Pancreatic Cancer Action Network is a nationwide network of people dedicated to working together to advance research, support patients and create hope for those affected by pancreatic cancer.

http://www.pancan.org

Last Updated: 20 Feb 2013

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The Lustgarten Foundation

The Lustgarten Foundation is committed to advancing the scientific and medical research related to the diagnosis, treatment, cure and prevention of pancreatic cancer.

http://www.lustgarten.org

Last Updated: 20 Feb 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Pancreatic cancer" returned 4716 free, full-text research articles on human participants. First 3 results:

Validation of full-field optical coherence tomography in distinguishing malignant and benign tissue in resected pancreatic cancer specimens.
 

Author(s): Labrinus van Manen, Paulien L Stegehuis, Arantza Fariña-Sarasqueta, Lorraine M de Haan, Jeroen Eggermont, Bert A Bonsing, Hans Morreau, Boudewijn P F Lelieveldt, Cornelis J H van de Velde, Alexander L Vahrmeijer, Jouke Dijkstra, J Sven D Mieog

Journal:

 

Pancreatic cancer is the fourth leading cause of cancer-related mortality in the United States. The minority of patients can undergo curative-intended surgical therapy due to progressive disease stage at time of diagnosis. Nonetheless, tumor involvement of surgical margins is seen ...

Last Updated: 17 Apr 2017

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The Neutrophil/Lymphocyte Ratio at Diagnosis Is Significantly Associated with Survival in Metastatic Pancreatic Cancer Patients.
 

Author(s): Matteo Piciucchi, Serena Stigliano, Livia Archibugi, Giulia Zerboni, Marianna Signoretti, Viola Barucca, Roberto Valente, Gianfranco Delle Fave, Gabriele Capurso

Journal:

 

Different inflammation-based scores such as the neutrophil/lymphocyte ratio (NLR), the Odonera Prognostic Nutritional Index (PNI), the Glasgow Prognostic Score, the platelet/lymphocyte ratio, and the C-reactive protein/albumin ratio have been found to be significantly associated with ...

Last Updated: 29 Mar 2017

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Endogenously Expressed IL-4Rα Promotes the Malignant Phenotype of Human Pancreatic Cancer In Vitro and In Vivo.
 

Author(s): Benno Traub, Lie Sun, Yongsu Ma, Pengfei Xu, Johannes Lemke, Stephan Paschke, Doris Henne-Bruns, Uwe Knippschild, Marko Kornmann

Journal:

 

Exogenous interleukin-4 (IL-4) has been demonstrated to affect the growth of different human malignancies including pancreatic cancer cells. The aim of our study was to determine the role of endogenously expressed IL-4-receptor-α-chain (IL-4Rα) in pancreatic cancer cells. IL-4Rα-suppression ...

Last Updated: 28 Mar 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Pancreatic cancer" returned 667 free, full-text review articles on human participants. First 3 results:

Molecular Drivers of Pancreatic Cancer Pathogenesis: Looking Inward to Move Forward.
 

Author(s): Mohammad Aslam Aslam Khan, Shafquat Azim, Haseeb Zubair, Arun Bhardwaj, Girijesh Kumar Patel, Moh'd Khushman, Seema Singh, Ajay Pratap Singh

Journal:

 

Pancreatic cancer (PC) continues to rank among the most lethal cancers. The consistent increase in incidence and mortality has made it the seventh leading cause of cancer-associated deaths globally and the third in the United States. The biggest challenge in combating PC is our insufficient ...

Last Updated: 6 Apr 2017

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Clinical Outcomes of Specific Immunotherapy in Advanced Pancreatic Cancer: A Systematic Review and Meta-Analysis.
 

Author(s): Jiang Chen, Guo Xiao-Zhong, Xing-Shun Qi

Journal: J Immunol Res. 2017 ;2017():8282391.

 

Specific immunotherapies, including vaccines with autologous tumor cells and tumor antigen-specific monoclonal antibodies, are important treatments for PC patients. To evaluate the clinical outcomes of PC-specific immunotherapy, we performed a systematic review and meta-analysis of ...

Last Updated: 7 Mar 2017

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Natural Products as Adjunctive Treatment for Pancreatic Cancer: Recent Trends and Advancements.
 

Author(s): Qingxi Yue, Guogang Gao, Gangyong Zou, Haiqing Yu, Xi Zheng

Journal: Biomed Res Int. 2017 ;2017():8412508.

 

Pancreatic cancer is a type of common malignant tumors with high occurrence in the world. Most patients presented in clinic had pancreatic cancer at advanced stages. Furthermore, chemotherapy or radiotherapy had very limited success in treating pancreatic cancer. Complementary and ...

Last Updated: 24 Feb 2017

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Systematic Hereditary Pancreatic Cancer Risk Assessment and Implications for Personalized Therapy
 

Status: Not yet recruiting

Condition Summary: Pancreatic Cancer

 

Last Updated: 17 Feb 2017

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Evaluation of Prognosis With Integrated MRI/PET in Patients With Pancreatic Cancer
 

Status: Recruiting

Condition Summary: Pancreatic Cancer

 

Last Updated: 12 Apr 2016

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Pancreatic Cancer Genetics
 

Status: Recruiting

Condition Summary: Pancreatic Cancer

 

Last Updated: 2 Jul 2015

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