Pancreatic cancer

Common Name(s)

Pancreatic cancer

Pancreatic cancer occurs when cells of the pancreas grow abnormally to form a tumor. The pancreas is a gland that normally makes juices that help break down food and produces insulin and other hormones. Pancreatic cancer usually doesn't cause symptoms right away, but can cause yellowing of the skin and eyes, pain in the abdomen and back, weight loss, and fatigue. Some risk factors for developing pancreatic cancer include smoking, long-term diabetes, chronic pancreatitis, and certain hereditary disorders. Because pancreatic cancer is often found late and it spreads quickly, it can be hard to treat. Possible treatments include surgery, radiation, and chemotherapy.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Pancreatic cancer" for support, advocacy or research.

Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

Last Updated: 29 Jul 2015

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Pancreatic Cancer Action Network

The Pancreatic Cancer Action Network is a nationwide network of people dedicated to working together to advance research, support patients and create hope for those affected by pancreatic cancer.

Last Updated: 20 Feb 2013

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The Lustgarten Foundation

The Lustgarten Foundation is committed to advancing the scientific and medical research related to the diagnosis, treatment, cure and prevention of pancreatic cancer.

Last Updated: 20 Feb 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Pancreatic cancer" for support, advocacy or research.

Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

http://www.CancerHopeNetwork.org

Last Updated: 29 Jul 2015

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Pancreatic Cancer Action Network

The Pancreatic Cancer Action Network is a nationwide network of people dedicated to working together to advance research, support patients and create hope for those affected by pancreatic cancer.

http://www.pancan.org

Last Updated: 20 Feb 2013

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The Lustgarten Foundation

The Lustgarten Foundation is committed to advancing the scientific and medical research related to the diagnosis, treatment, cure and prevention of pancreatic cancer.

http://www.lustgarten.org

Last Updated: 20 Feb 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Pancreatic cancer" returned 4657 free, full-text research articles on human participants. First 3 results:

Effect of Body Mass Index on Overall Survival of Pancreatic Cancer: A Meta-Analysis.
 

Author(s): Yu-Qi Shi, Jing Yang, Peng Du, Ting Xu, Xiao-Hui Zhuang, Jia-Qing Shen, Chun-Fang Xu

Journal: Medicine (Baltimore). 2016 Apr;95(14):e3305.

 

Although obesity has been identified as a risk factor for pancreatic cancer, the important question of whether obesity influences the prognosis of pancreatic cancer has not been explicated thoroughly. We therefore performed a meta-analysis to investigate the association between body ...

Last Updated: 9 Apr 2016

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Early Gastric Cancer Recurrence Following Curative Resection Presenting as Biliary Tract Dilatation, Pancreatic Duct Dilatation and Intestinal Wall Thickening.
 

Author(s): Hiroyuki Kato, Yukiko Ito, Eri Tanaka, Kensaku Noguchi, Shinzo Yamamoto, Hiroyoshi Taniguchi, Hideo Yoshida, Toshio Kumasaka, Ryo Nakata

Journal: Intern. Med.. 2016 ;55(7):745-50.

 

Early gastric cancer, especially cancer confined to the mucosa (stage T1a), is known to have a high cure rate with rare recurrence. We herein report the case of a 40-year-old female who initially presented with biliary tract dilatation, pancreatic duct dilatation and intestinal wall ...

Last Updated: 4 Apr 2016

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Phosphoproteome Analysis of Invasion and Metastasis-Related Factors in Pancreatic Cancer Cells.
 

Author(s): Xiaodong Tan, Peng Liu, Yinpeng Huang, Lei Zhou, Yifan Yang, Huaitao Wang, Boqiang Yu, Xiangli Meng, Xiaobo Zhang, Feng Gao

Journal:

 

Mechanisms of abnormal protein phosphorylation that regulate cell invasion and metastasis in pancreatic cancer remain obscure. In this study, we used high-throughput phosphorylation array to test two pancreatic cancer cell lines (PC-1 cells with a low, and PC-1.0 cells with a high ...

Last Updated: 26 Mar 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Pancreatic cancer" returned 606 free, full-text review articles on human participants. First 3 results:

Distal Pancreatectomy With En Bloc Celiac Axis Resection for Locally Advanced Pancreatic Cancer: A Systematic Review and Meta-Analysis.
 

Author(s): Haibing Gong, Ruirui Ma, Jian Gong, Chengzong Cai, Zhenshun Song, Bin Xu

Journal: Medicine (Baltimore). 2016 Mar;95(10):e3061.

 

Although distal pancreatectomy with en bloc celiac resection (DP-CAR) is used to treat locally advanced pancreatic cancer, the advantages and disadvantages of this surgical procedure remain unclear. The purpose of this study was to evaluate its clinical safety and efficacy.Studies ...

Last Updated: 11 Mar 2016

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Hedgehog Signaling in Pancreatic Fibrosis and Cancer.
 

Author(s): Yongyu Bai, Yongheng Bai, Jiaojiao Dong, Qiang Li, Yuepeng Jin, Bicheng Chen, Mengtao Zhou

Journal: Medicine (Baltimore). 2016 Mar;95(10):e2996.

 

The hedgehog signaling pathway was first discovered in the 1980s. It is a stem cell-related pathway that plays a crucial role in embryonic development, tissue regeneration, and organogenesis. Aberrant activation of hedgehog signaling leads to pathological consequences, including a ...

Last Updated: 11 Mar 2016

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[Pancreatic cancer--mechanisms of chemoresistance].
 

Author(s): Barbara Borowa-Mazgaj

Journal:

 

Despite the enormous progress made over the past decades in diagnosis, treatment and prevention of many types of tumor, the survival rate for pancreatic cancer still remains poor. Pancreatic cancer is one of the most malignant and chemotherapy-resistant tumors. That is mainly due ...

Last Updated: 5 Mar 2016

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Second-Line Adjuvant Therapy With Nab-Paclitaxel Plus Gemcitabine Versus Oxaliplatin Plus Folinic Acid and Fluorouracil for Gemcitabine-Refractory Pancreatic Cancer After Curative Resection
 

Status: Recruiting

Condition Summary: Stage ⅠA Pancreatic Cancer; Stage ⅠB Pancreatic Cancer; Stage ⅡA Pancreatic Cancer; Stage ⅡB Pancreatic Cancer

 

Last Updated: 10 Aug 2016

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Weekly Dosing of an Integrative Chemotherapy Combination to Treat Advanced Pancreatic Cancer
 

Status: Recruiting

Condition Summary: Adenocarincoma of Pancreas; Stage III Pancreatic Cancer; Stage IVA Pancreatic Cancer; Stage IVB Pancreatic Cancer

 

Last Updated: 7 May 2007

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A Study of Vantictumab (OMP-18R5) in Combination With Nab-Paclitaxel and Gemcitabine in Previously Untreated Stage IV Pancreatic Cancer
 

Status: Recruiting

Condition Summary: Pancreatic Cancer; Stage IV Pancreatic Cancer

 

Last Updated: 5 Aug 2016

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