Pancreatic cancer

Common Name(s)

Pancreatic cancer

Pancreatic cancer occurs when cells of the pancreas grow abnormally to form a tumor. The pancreas is a gland that normally makes juices that help break down food and produces insulin and other hormones. Pancreatic cancer usually doesn't cause symptoms right away, but can cause yellowing of the skin and eyes, pain in the abdomen and back, weight loss, and fatigue. Some risk factors for developing pancreatic cancer include smoking, long-term diabetes, chronic pancreatitis, and certain hereditary disorders. Because pancreatic cancer is often found late and it spreads quickly, it can be hard to treat. Possible treatments include surgery, radiation, and chemotherapy.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Pancreatic cancer" for support, advocacy or research.

Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

Last Updated: 29 Jul 2015

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Pancreatic Cancer Action Network

The Pancreatic Cancer Action Network is a nationwide network of people dedicated to working together to advance research, support patients and create hope for those affected by pancreatic cancer.

Last Updated: 20 Feb 2013

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The Lustgarten Foundation

The Lustgarten Foundation is committed to advancing the scientific and medical research related to the diagnosis, treatment, cure and prevention of pancreatic cancer.

Last Updated: 20 Feb 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Pancreatic cancer" for support, advocacy or research.

Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

http://www.CancerHopeNetwork.org

Last Updated: 29 Jul 2015

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Pancreatic Cancer Action Network

The Pancreatic Cancer Action Network is a nationwide network of people dedicated to working together to advance research, support patients and create hope for those affected by pancreatic cancer.

http://www.pancan.org

Last Updated: 20 Feb 2013

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The Lustgarten Foundation

The Lustgarten Foundation is committed to advancing the scientific and medical research related to the diagnosis, treatment, cure and prevention of pancreatic cancer.

http://www.lustgarten.org

Last Updated: 20 Feb 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Pancreatic cancer" returned 4299 free, full-text research articles on human participants. First 3 results:

Systemic Therapy of Pancreatic Cancer: Better Science, Faster Progress.
 

Author(s): Philip A Philip

Journal: Oncology (Williston Park, N.Y.). 2015 Nov;29(11):821, 826.

 

Last Updated: 17 Nov 2015

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Health-Related Quality of Life in SCALOP, a Randomized Phase 2 Trial Comparing Chemoradiation Therapy Regimens in Locally Advanced Pancreatic Cancer.
 

Author(s): Christopher N Hurt, Somnath Mukherjee, John Bridgewater, Stephen Falk, Tom Crosby, Alec McDonald, George Joseph, John Staffurth, Ross A Abrams, Jane M Blazeby, Sarah Bridges, Peter Dutton, Gareth Griffiths, Tim Maughan, Colin Johnson

Journal: Int. J. Radiat. Oncol. Biol. Phys.. 2015 Nov;93(4):810-8.

 

Chemoradiation therapy (CRT) for patients with locally advanced pancreatic cancer (LAPC) provides survival benefits but may result in considerable toxicity. Health-related quality of life (HRQL) measurements during CRT have not been widely reported. This paper reports HRQL data from ...

Last Updated: 4 Nov 2015

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Integrative analysis of multi-omics data for identifying multi-markers for diagnosing pancreatic cancer.
 

Author(s): Min-Seok Kwon, Yongkang Kim, Seungyeoun Lee, Junghyun Namkung, Taegyun Yun, Sung Gon Yi, Sangjo Han, Meejoo Kang, Sun Whe Kim, Jin-Young Jang, Taesung Park

Journal: BMC Genomics. 2015 ;16 Suppl 9():S4.

 

microRNA (miRNA) expression plays an influential role in cancer classification and malignancy, and miRNAs are feasible as alternative diagnostic markers for pancreatic cancer, a highly aggressive neoplasm with silent early symptoms, high metastatic potential, and resistance to conventional ...

Last Updated: 2 Sep 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Pancreatic cancer" returned 574 free, full-text review articles on human participants. First 3 results:

Localized Autoimmune Pancreatitis: Report of a Case Clinically Mimicking Pancreatic Cancer and a Literature Review.
 

Author(s): Zhe Cao, Rui Tian, Taiping Zhang, Yupei Zhao

Journal: Medicine (Baltimore). 2015 Oct;94(42):e1656.

 

Autoimmune pancreatitis (AIP) is a rare disease with clinical presentations that greatly mimic pancreatic cancer (PC). It is critical for clinicians to distinguish AIP from PC because their treatments and prognoses are entirely different. Typical images show characteristic features ...

Last Updated: 27 Oct 2015

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Differential diagnosis of pancreatic cancer by single-shot echo-planar imaging diffusion-weighted imaging.
 

Author(s): Ben-Zu Hong, Xin-Feng Li, Jian-Qing Lin

Journal: World J. Gastroenterol.. 2015 May;21(20):6374-80.

 

To investigate the diagnostic ability of single-shot echo-planar imaging (EPI) diffusion-weighted imaging (DWI) to differentiate between malignant and benign pancreatic lesions.

Last Updated: 2 Jun 2015

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New targeted therapies in pancreatic cancer.
 

Author(s): Andrada Seicean, Livia Petrusel, Radu Seicean

Journal: World J. Gastroenterol.. 2015 May;21(20):6127-45.

 

Patients with pancreatic cancer have a poor prognosis with a median survival of 4-6 mo and a 5-year survival of less than 5%. Despite therapy with gemcitabine, patient survival does not exceed 6 mo, likely due to natural resistance to gemcitabine. Therefore, it is hoped that more ...

Last Updated: 2 Jun 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Second-Line Adjuvant Therapy With Nab-Paclitaxel Plus Gemcitabine Versus Oxaliplatin Plus Folinic Acid and Fluorouracil for Gemcitabine-Refractory Pancreatic Cancer After Curative Resection
 

Status: Recruiting

Condition Summary: Stage ⅠA Pancreatic Cancer; Stage ⅠB Pancreatic Cancer; Stage ⅡA Pancreatic Cancer; Stage ⅡB Pancreatic Cancer

 

Last Updated: 2 Feb 2016

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Weekly Dosing of an Integrative Chemotherapy Combination to Treat Advanced Pancreatic Cancer
 

Status: Recruiting

Condition Summary: Adenocarincoma of Pancreas; Stage III Pancreatic Cancer; Stage IVA Pancreatic Cancer; Stage IVB Pancreatic Cancer

 

Last Updated: 7 May 2007

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A Study of Vantictumab (OMP-18R5) in Combination With Nab-Paclitaxel and Gemcitabine in Previously Untreated Stage IV Pancreatic Cancer
 

Status: Recruiting

Condition Summary: Pancreatic Cancer; Stage IV Pancreatic Cancer

 

Last Updated: 31 Aug 2015

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