Pancreatic cancer

Common Name(s)

Pancreatic cancer

Pancreatic cancer occurs when cells of the pancreas grow abnormally to form a tumor. The pancreas is a gland that normally makes juices that help break down food and produces insulin and other hormones. Pancreatic cancer usually doesn't cause symptoms right away, but can cause yellowing of the skin and eyes, pain in the abdomen and back, weight loss, and fatigue. Some risk factors for developing pancreatic cancer include smoking, long-term diabetes, chronic pancreatitis, and certain hereditary disorders. Because pancreatic cancer is often found late and it spreads quickly, it can be hard to treat. Possible treatments include surgery, radiation, and chemotherapy.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Pancreatic cancer" for support, advocacy or research.

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Pancreatic Cancer Action Network

The Pancreatic Cancer Action Network is a nationwide network of people dedicated to working together to advance research, support patients and create hope for those affected by pancreatic cancer.

Last Updated: 20 Feb 2013

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The Lustgarten Foundation

The Lustgarten Foundation is committed to advancing the scientific and medical research related to the diagnosis, treatment, cure and prevention of pancreatic cancer.

Last Updated: 20 Feb 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Pancreatic cancer" for support, advocacy or research.

Logo
Pancreatic Cancer Action Network

The Pancreatic Cancer Action Network is a nationwide network of people dedicated to working together to advance research, support patients and create hope for those affected by pancreatic cancer.

http://www.pancan.org

Last Updated: 20 Feb 2013

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The Lustgarten Foundation

The Lustgarten Foundation is committed to advancing the scientific and medical research related to the diagnosis, treatment, cure and prevention of pancreatic cancer.

http://www.lustgarten.org

Last Updated: 20 Feb 2013

View Details

 

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Pancreatic cancer" returned 3299 free, full-text research articles on human participants. First 3 results:

miR-212 promotes pancreatic cancer cell growth and invasion by targeting the hedgehog signaling pathway receptor patched-1.
 

Author(s): Chenchao Ma, Kate Nong, Bo Wu, Bo Dong, Yueqing Bai, Hongda Zhu, Weiwei Wang, Xinyu Huang, Zhou Yuan, Kaixing Ai

Journal:

 

microRNAs (miRNAs) are a class of small non-coding RNAs that play important roles in carcinogenesis. In the present study, we investigated the effect of miR-212 on pancreatic ductal adenocarcinoma (PDAC) and its target protein.

Last Updated: 9 Jul 2014

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Thoracoscopic left splanchnicectomy - role in pain control in unresectable pancreatic cancer. Initial experience.
 

Author(s): I Lică, G Jinescu, C Pavelescu, M Beuran

Journal: Chirurgia (Bucur). ;109(3):313-7.

 

The management of opiate-dependent intractable abdominal pain caused by unresectable pancreatic cancer remains challenging. The aim of this study was to evaluate the safety and efficacy of thoracoscopic unilateral left splanchnicectomy for pain control in a first series of 15 patients ...

Last Updated: 24 Jun 2014

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Surface engineered antifouling optomagnetic SPIONs for bimodal targeted imaging of pancreatic cancer cells.
 

Author(s): Xiaohui Wang, Xiaohong Xing, Bingbo Zhang, Fengjun Liu, Yingsheng Cheng, Donglu Shi

Journal:

 

Targeted imaging contrast agents for early pancreatic ductal adenocarcinoma diagnosis was developed using superparamagnetic iron oxide nanoparticles (SPIONs). For phase transfer of SPIONs, the hydrophobic SPIONs are first treated with tetrafluoroborate and then capped by bovine serum ...

Last Updated: 17 Apr 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Pancreatic cancer" returned 401 free, full-text review articles on human participants. First 3 results:

Celiac plexus neurolysis in pancreatic cancer: the endoscopic ultrasound approach.
 

Author(s): Andrada Seicean

Journal: World J. Gastroenterol.. 2014 Jan;20(1):110-7.

 

Pain in pancreatic cancer is often a major problem of treatment. Administration of opioids is frequently limited by side effects or insufficient analgesia. Endoscopic ultrasound-guided celiac plexus neurolysis (EUS-CPN) represents an alternative for the palliative treatment of visceral ...

Last Updated: 13 Jan 2014

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Familial pancreatic cancer: genetic advances.
 

Author(s): Anil K Rustgi

Journal: Genes Dev.. 2014 Jan;28(1):1-7.

 

Beset by poor prognosis, pancreatic ductal adenocarcinoma is classified as familial or sporadic. This review elaborates on the known genetic syndromes that underlie familial pancreatic cancer, where there are opportunities for genetic counseling and testing as well as clinical monitoring ...

Last Updated: 7 Jan 2014

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Pancreatic solitary and synchronous metastasis from breast cancer: a case report and systematic review of controversies in diagnosis and treatment.
 

Author(s): Carlo Molino, Carmela Mocerino, Antonio Braucci, Ferdinando Riccardi, Martino Trunfio, Giovanna Carrillo, Maria Giuseppa Vitale, Giacomo Cartenì, Guido De Sena,

Journal:

 

Metastases from breast cancer cause the frequent involvement of lung, bone, liver, and brain, while the occurrence of metastases to the gastrointestinal tract is rare, and more frequently discovered after a primary diagnosis of breast cancer. Solitary pancreatic metastases from breast ...

Last Updated: 10 Jan 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Gemcitabine and CT-011 for Resected Pancreatic Cancer
 

Status: Recruiting

Condition Summary: Pancreatic Neoplasms; Cancer of the Pancreas; Neoplasms Pancreatic; Pancreatic Cancer; Pancreas Cancer

 

Last Updated: 12 Aug 2014

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Weekly Dosing of an Integrative Chemotherapy Combination to Treat Advanced Pancreatic Cancer
 

Status: Recruiting

Condition Summary: Adenocarincoma of Pancreas; Stage III Pancreatic Cancer; Stage IVA Pancreatic Cancer; Stage IVB Pancreatic Cancer

 

Last Updated: 7 May 2007

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DCE MRI in Diagnosing Patients With Pancreatic Cancer
 

Status: Recruiting

Condition Summary: Hereditary Pancreatic Cancer; Intraductal Papillary Mucinous Neoplasm of the Pancreas; Recurrent Pancreatic Cancer; Stage III Pancreatic Cancer; Stage IV Pancreatic Cancer

 

Last Updated: 22 Aug 2014

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