Pancreatic cancer

Common Name(s)

Pancreatic cancer

Pancreatic cancer occurs when cells of the pancreas grow abnormally to form a tumor. The pancreas is a gland that normally makes juices that help break down food and produces insulin and other hormones. Pancreatic cancer usually doesn't cause symptoms right away, but can cause yellowing of the skin and eyes, pain in the abdomen and back, weight loss, and fatigue. Some risk factors for developing pancreatic cancer include smoking, long-term diabetes, chronic pancreatitis, and certain hereditary disorders. Because pancreatic cancer is often found late and it spreads quickly, it can be hard to treat. Possible treatments include surgery, radiation, and chemotherapy.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Pancreatic cancer" for support, advocacy or research.

Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

Last Updated: 29 Jul 2015

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Pancreatic Cancer Action Network

The Pancreatic Cancer Action Network is a nationwide network of people dedicated to working together to advance research, support patients and create hope for those affected by pancreatic cancer.

Last Updated: 20 Feb 2013

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The Lustgarten Foundation

The Lustgarten Foundation is committed to advancing the scientific and medical research related to the diagnosis, treatment, cure and prevention of pancreatic cancer.

Last Updated: 20 Feb 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Pancreatic cancer" for support, advocacy or research.

Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

http://www.CancerHopeNetwork.org

Last Updated: 29 Jul 2015

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Pancreatic Cancer Action Network

The Pancreatic Cancer Action Network is a nationwide network of people dedicated to working together to advance research, support patients and create hope for those affected by pancreatic cancer.

http://www.pancan.org

Last Updated: 20 Feb 2013

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The Lustgarten Foundation

The Lustgarten Foundation is committed to advancing the scientific and medical research related to the diagnosis, treatment, cure and prevention of pancreatic cancer.

http://www.lustgarten.org

Last Updated: 20 Feb 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Pancreatic cancer" returned 4683 free, full-text research articles on human participants. First 3 results:

No association between metformin use and survival in patients with pancreatic cancer: An observational cohort study.
 

Author(s): Martine A Frouws, Babs G Sibinga Mulder, Esther Bastiaannet, Marjolein M J Zanders, Myrthe P P van Herk-Sukel, Eleonora M de Leede, Bert A Bonsing, J Sven D Mieog, Cornelis J H Van de Velde, Gerrit-Jan Liefers

Journal: Medicine (Baltimore). 2017 Mar;96(10):e6229.

 

Several studies have suggested an association between use of metformin and an increased overall survival in patients diagnosed with pancreatic cancer, however with several important methodological limitations. The aim of the study was to assess the association between overall survival, ...

Last Updated: 8 Mar 2017

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Helicobacter pylori infection and pancreatic cancer risk: A meta-analysis.
 

Author(s): Yu Guo, Wei Liu, Jun Wu

Journal: J Cancer Res Ther. 2016 Dec;12(Supplement):C229-C232.

 

To assess whether the Helicobacter pylori (HP) infection can increase the risk of developing pancreatic cancer or not by meta-analysis.

Last Updated: 23 Feb 2017

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MiR-451 Promotes Cell Proliferation and Metastasis in Pancreatic Cancer through Targeting CAB39.
 

Author(s): Rende Guo, Jianhua Gu, Zhibin Zhang, Yi Wang, Chuan Gu

Journal: Biomed Res Int. 2017 ;2017():2381482.

 

Emerging evidence shows that microRNAs (miRNAs) play important roles in the regulation of various biological and pathologic processes in human cancers and the aberrant expression of miRNAs contributes to the tumor development. In this study, our findings indicate that miR-451 is significantly ...

Last Updated: 15 Feb 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Pancreatic cancer" returned 650 free, full-text review articles on human participants. First 3 results:

Natural Products as Adjunctive Treatment for Pancreatic Cancer: Recent Trends and Advancements.
 

Author(s): Qingxi Yue, Guogang Gao, Gangyong Zou, Haiqing Yu, Xi Zheng

Journal: Biomed Res Int. 2017 ;2017():8412508.

 

Pancreatic cancer is a type of common malignant tumors with high occurrence in the world. Most patients presented in clinic had pancreatic cancer at advanced stages. Furthermore, chemotherapy or radiotherapy had very limited success in treating pancreatic cancer. Complementary and ...

Last Updated: 24 Feb 2017

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The Role of BRCA2 Mutation Status as Diagnostic, Predictive, and Prognosis Biomarker for Pancreatic Cancer.
 

Author(s): Javier Martinez-Useros, Jesus Garcia-Foncillas

Journal: Biomed Res Int. 2016 ;2016():1869304.

 

Pancreatic cancer is one of the deadliest cancers worldwide, and life expectancy after diagnosis is often short. Most pancreatic tumours appear sporadically and have been highly related to habits such as cigarette smoking, high alcohol intake, high carbohydrate, and sugar consumption. ...

Last Updated: 12 Jan 2017

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Role of immune cells in pancreatic cancer from bench to clinical application: An updated review.
 

Author(s): Jae Hyuck Chang, Yongjian Jiang, Venu G Pillarisetty

Journal: Medicine (Baltimore). 2016 Dec;95(49):e5541.

 

Pancreatic cancer (PC) remains difficult to treat, despite the recent advances in various anticancer therapies. Immuno-inflammatory response is considered to be a major risk factor for the development of PC in addition to a combination of genetic background and environmental factors. ...

Last Updated: 8 Dec 2016

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Systematic Hereditary Pancreatic Cancer Risk Assessment and Implications for Personalized Therapy
 

Status: Not yet recruiting

Condition Summary: Pancreatic Cancer

 

Last Updated: 17 Feb 2017

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Evaluation of Prognosis With Integrated MRI/PET in Patients With Pancreatic Cancer
 

Status: Recruiting

Condition Summary: Pancreatic Cancer

 

Last Updated: 12 Apr 2016

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Pancreatic Cancer Genetics
 

Status: Recruiting

Condition Summary: Pancreatic Cancer

 

Last Updated: 2 Jul 2015

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