Paget Disease

Common Name(s)

Paget Disease

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Paget Disease" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Paget Disease" returned 44 free, full-text research articles on human participants. First 3 results:

Paget disease of bone-associated UBA domain mutations of SQSTM1 exert distinct effects on protein structure and function.
 

Author(s): Alice Goode, Jed E Long, Barry Shaw, Stuart H Ralston, Micaela Rios Visconti, Fernando Gianfrancesco, Teresa Esposito, Luigi Gennari, Daniela Merlotti, Domenico Rendina, Sarah L Rea, Melanie Sultana, Mark S Searle, Robert Layfield

Journal: Biochim. Biophys. Acta. 2014 Jul;1842(7):992-1000.

 

SQSTM1 mutations are common in patients with Paget disease of bone (PDB), with most affecting the C-terminal ubiquitin-associated (UBA) domain of the SQSTM1 protein. We performed structural and functional analyses of two UBA domain mutations, an I424S mutation relatively common in ...

Last Updated: 12 May 2014

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Paget disease of bone in Japanese patients: a report of three cases.
 

Author(s): Satoshi Nagano, Masahiro Yokouchi, Ryusaku Nagayoshi, Hiromi Sasaki, Hirofumi Shimada, Takao Setoguchi, Kosei Ijiri, Setsuro Komiya

Journal: J Orthop Surg (Hong Kong). 2013 Dec;21(3):375-9.

 

Paget disease of bone (PDB) is a bone metabolic disorder causing pain, fractures, and deformity. Its incidence is estimated to be 1 to 2% in Caucasians older than 55 years, but in Asian populations the incidence is rare. We report on 2 female and one male Japanese patients aged 46 ...

Last Updated: 24 Dec 2013

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Mammary Paget disease.
 

Author(s): Michael J Burke, Tracy O Middleton

Journal: J Am Osteopath Assoc. 2013 Sep;113(9):712.

 

Last Updated: 5 Sep 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Paget Disease" returned 6 free, full-text review articles on human participants. First 3 results:

Paget disease of bone: diagnosis and drug therapy.
 

Author(s): Margaret Seton

Journal: Cleve Clin J Med. 2013 Jul;80(7):452-62.

 

Paget disease of bone is a focal disorder of aging bone that may be asymptomatic or may present with pain, bowing deformity, fracture, or a nonspecific rheumatic complaint. It is the second most common disease of bone in the elderly after osteoporosis, and the loss of structural integrity ...

Last Updated: 3 Jul 2013

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Extramammary Paget disease.
 

Author(s): Rachael Hartman, Julie Chu, Rishi Patel, Shane Meehan, Jennifer A Stein

Journal:

 

We report the case of a 60-year-old man with penile-scrotal extramammary Paget disease (EMPD). The patient initially underwent Mohs micrographic surgery, but the margins remained positive after several sections; multiple scouting punch biopsies used to define the extent of the tumor ...

Last Updated: 27 Oct 2011

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A Brazilian family with hereditary inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia.
 

Author(s): R D Fanganiello, V E Kimonis, C C Côrte, R Nitrini, M R Passos-Bueno

Journal: Braz. J. Med. Biol. Res.. 2011 Apr;44(4):374-80.

 

Inclusion body myopathy associated with Paget disease and frontotemporal dementia (IBMPFD) is a progressive and usually misdiagnosed autosomal dominant disorder. It is clinically characterized by a triad of features: proximal and distal myopathy, early onset Paget disease of bone ...

Last Updated: 12 Apr 2011

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Characterization of Inclusion Body Myopathy Associated With Paget's Disease of Bone and Frontotemporal Dementia (IBMPFD)
 

Status: Recruiting

Condition Summary: Inclusion Body Myopathy With Early-onset Paget Disease and Frontotemporal Dementia; Paget Disease of Bone; Frontotemporal Dementia; Myopathy

 

Last Updated: 12 May 2011

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Docosahexaenoic Acid in Preventing Recurrence in Breast Cancer Survivors
 

Status: Recruiting

Condition Summary: Ductal Breast Carcinoma in Situ; Lobular Breast Carcinoma in Situ; Paget Disease of the Breast; Stage IA Breast Cancer; Stage IB Breast Cancer; Stage II Breast Cancer; Stage IIIA Breast Cancer; Stage IIIB Breast Cancer; Stage IIIC Breast Cancer

 

Last Updated: 16 Oct 2014

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