Paget Disease

Common Name(s)

Paget Disease

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Paget Disease" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Paget Disease" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Paget Disease" returned 45 free, full-text research articles on human participants. First 3 results:

Synchronous Paget disease of the breast and axilla.
 

Author(s): Keiju Kobayashi, Yasuyuki Sumikawa, Yumiko Kikuchi, Yuji Kan, Junji Kato, Fukino Satomi, Hiroaki Shima, Goro Kutomi, Toshiharu Yamashita

Journal: J. Am. Acad. Dermatol.. 2015 Jan;72(1):e44-5.

 

Last Updated: 16 Dec 2014

Go To URL
[Paget´s disease of the mandible: a differential diagnosis of the osteomyelitis of the jaw].
 

Author(s): Niels Christian Pausch, Alexander Hemprich, Dirk Halama

Journal: Swiss Dent J. 2014 ;124(3):325-32.

 

Paget´s disease of bone is a common, progressive disorder with uncertain etiology. It results in the replacement of normal skeletal areas with highly vascularized, low density bone. The most frequent symptom is bone pain, which is a result of periostal irritation due to increased ...

Last Updated: 9 Apr 2014

Go To URL
Paget disease of bone-associated UBA domain mutations of SQSTM1 exert distinct effects on protein structure and function.
 

Author(s): Alice Goode, Jed E Long, Barry Shaw, Stuart H Ralston, Micaela Rios Visconti, Fernando Gianfrancesco, Teresa Esposito, Luigi Gennari, Daniela Merlotti, Domenico Rendina, Sarah L Rea, Melanie Sultana, Mark S Searle, Robert Layfield

Journal: Biochim. Biophys. Acta. 2014 Jul;1842(7):992-1000.

 

SQSTM1 mutations are common in patients with Paget disease of bone (PDB), with most affecting the C-terminal ubiquitin-associated (UBA) domain of the SQSTM1 protein. We performed structural and functional analyses of two UBA domain mutations, an I424S mutation relatively common in ...

Last Updated: 12 May 2014

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Paget Disease" returned 5 free, full-text review articles on human participants. First 3 results:

Extramammary Paget disease.
 

Author(s): Rachael Hartman, Julie Chu, Rishi Patel, Shane Meehan, Jennifer A Stein

Journal:

 

We report the case of a 60-year-old man with penile-scrotal extramammary Paget disease (EMPD). The patient initially underwent Mohs micrographic surgery, but the margins remained positive after several sections; multiple scouting punch biopsies used to define the extent of the tumor ...

Last Updated: 27 Oct 2011

Go To URL
A Brazilian family with hereditary inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia.
 

Author(s): R D Fanganiello, V E Kimonis, C C Côrte, R Nitrini, M R Passos-Bueno

Journal: Braz. J. Med. Biol. Res.. 2011 Apr;44(4):374-80.

 

Inclusion body myopathy associated with Paget disease and frontotemporal dementia (IBMPFD) is a progressive and usually misdiagnosed autosomal dominant disorder. It is clinically characterized by a triad of features: proximal and distal myopathy, early onset Paget disease of bone ...

Last Updated: 12 Apr 2011

Go To URL
Treatment of recurrent vulvar Paget disease with imiquimod cream: a case report and review of the literature.
 

Author(s): Esra Tonguc, Tayfun Güngor, Turgut Var, Mustafa Ozat, Izzet Sahin, Levent Sirvan

Journal: Arch. Gynecol. Obstet.. 2011 Jan;283(1):97-101.

 

Extra-mammary Paget disease is one of the rare neoplastic conditions of the skin. The most common site of involvement is the vulva and presents itself with erythematous plaques. Surgery is the most important treatment option. In the recent years, there are publications of the topical ...

Last Updated: 3 Jan 2011

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Topical 5% Imiquimod Cream for Vulvar Paget's Disease
 

Status: Recruiting

Condition Summary: Paget Disease, Extramammary

 

Last Updated: 10 Mar 2015

Go to URL
Characterization of Inclusion Body Myopathy Associated With Paget's Disease of Bone and Frontotemporal Dementia (IBMPFD)
 

Status: Recruiting

Condition Summary: Inclusion Body Myopathy With Early-onset Paget Disease and Frontotemporal Dementia; Paget Disease of Bone; Frontotemporal Dementia; Myopathy

 

Last Updated: 12 May 2011

Go to URL