Paget Disease

Common Name(s)

Paget Disease

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Paget Disease" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Paget Disease" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Paget Disease" returned 56 free, full-text research articles on human participants. First 3 results:

ZNF687 Mutations in Severe Paget Disease of Bone Associated with Giant Cell Tumor.
 

Author(s): Giuseppina Divisato, Daniela Formicola, Teresa Esposito, Daniela Merlotti, Laura Pazzaglia, Andrea Del Fattore, Ethel Siris, Philippe Orcel, Jacques P Brown, Ranuccio Nuti, Pasquale Strazzullo, Maria Serena Benassi, M Leonor Cancela, Laetitia Michou, Domenico Rendina, Luigi Gennari, Fernando Gianfrancesco

Journal: Am. J. Hum. Genet.. 2016 Feb;98(2):275-86.

 

Paget disease of bone (PDB) is a skeletal disorder characterized by focal abnormalities of bone remodeling, which result in enlarged and deformed bones in one or more regions of the skeleton. In some cases, the pagetic tissue undergoes neoplastic transformation, resulting in osteosarcoma ...

Last Updated: 6 Feb 2016

Go To URL
The effect of Paget disease on axillary lymph node metastases and survival in invasive ductal carcinoma.
 

Author(s): Stephanie M Wong, Rachel A Freedman, Yasuaki Sagara, Emily F Stamell, Stephen D Desantis, William T Barry, Mehra Golshan

Journal: Cancer. 2015 Dec;121(24):4333-40.

 

The objective of this study was to examine the effect of Paget disease (PD) on axillary lymph node metastases and survival in patients who had concomitant invasive ductal carcinoma (PD-IDC).

Last Updated: 5 Dec 2015

Go To URL
Psoriasis with extramammary paget disease in a male: a case report.
 

Author(s): Junlian Liu, Wei Chen, Jinlian Zhou, Jianjun Liu, Jianzhong Zhang

Journal:

 

Psoriasis is a chronic inflammatory skin disease that is characterized by erythematous, sharply demarcated papules and plaques covered by scales. Extramammary Paget disease (EMPD) is a uncommon neoplastic condition of apocrine gland-bearing skin and its occurrence in combination with ...

Last Updated: 4 Sep 2015

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Paget Disease" returned 11 free, full-text review articles on human participants. First 3 results:

Paget disease of the vulva.
 

Author(s): M van der Linden, K A P Meeuwis, J Bulten, T Bosse, M I E van Poelgeest, J A de Hullu

Journal: Crit. Rev. Oncol. Hematol.. 2016 May;101():60-74.

 

In this review, we provide an overview of the clinical aspects, histopathology, molecular genetics, and treatment options for Vulvar Paget's Disease (VPD), a rare skin disease, most commonly found in postmenopausal Caucasian women. The underlying cause of VPD remains not well understood. ...

Last Updated: 23 Apr 2016

Go To URL
Auricular ossification: A newly recognized feature of osteoprotegerin-deficiency juvenile Paget disease.
 

Author(s): Gary S Gottesman, Katherine L Madson, William H McAlister, Angela Nenninger, Deborah Wenkert, Steven Mumm, Michael P Whyte

Journal: Am. J. Med. Genet. A. 2016 Apr;170A(4):978-85.

 

We report auricular ossification (AO) affecting the elastic cartilage of the ear as a newly recognized feature of osteoprotegerin (OPG)-deficiency juvenile Paget disease (JPD). AO and auricular calcification refer interchangeably to rigid pinnae, sparing the ear lobe, from various ...

Last Updated: 22 Mar 2016

Go To URL
A clinical series and literature review of the management of inguinal nodal metastases in patients with primary extramammary Paget disease of the scrotum.
 

Author(s): Ye Xin Koh, Timothy Kwang Yong Tay, Sheng Xu, Chee Meng Lee, Melissa Ching Ching Teo

Journal: Asian J Surg. 2015 Jan;38(1):40-6.

 

We describe a series of five patients with extramammary Paget disease of the scrotum with inguinal nodal metastases. These patients underwent combined groin dissection. All patients experienced invasion to the dermis. One patient had invasion of the dartos muscle, another had tumor ...

Last Updated: 2 Jan 2015

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Pathophysiology of Paget's Disease of Bone
 

Status: Recruiting

Condition Summary: Paget's Disease of Bone

 

Last Updated: 15 Jun 2016

Go to URL
Characterization of Inclusion Body Myopathy Associated With Paget's Disease of Bone and Frontotemporal Dementia (IBMPFD)
 

Status: Recruiting

Condition Summary: Inclusion Body Myopathy With Early-onset Paget Disease and Frontotemporal Dementia; Paget Disease of Bone; Frontotemporal Dementia; Myopathy

 

Last Updated: 12 May 2011

Go to URL
Characterization of Familial Myopathy and Paget Disease of Bone
 

Status: Recruiting

Condition Summary: Muscle Disorder; Bone Disorder

 

Last Updated: 8 Feb 2017

Go to URL