Paget Disease

Common Name(s)

Paget Disease

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Paget Disease" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Paget Disease" returned 59 free, full-text research articles on human participants. First 3 results:

Spinal Metastases of Extramammary Paget Disease with Radiologic-Pathologic Correlation.
 

Author(s): Jason T Little, Vance T Lehman, Jonathan M Morris, Julia S Lehman, Felix E Diehn

Journal:

 

Extramammary Paget disease (EMPD) is an uncommon malignancy. It manifests either in the primary form in the skin as an intraepithelial neoplasm, or in secondary form as pagetoid (intraepithelial) spread of an underlying internal carcinoma to the skin. Although local invasion and recurrence ...

Last Updated: 20 Oct 2016

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ZNF687 Mutations in Severe Paget Disease of Bone Associated with Giant Cell Tumor.
 

Author(s): Giuseppina Divisato, Daniela Formicola, Teresa Esposito, Daniela Merlotti, Laura Pazzaglia, Andrea Del Fattore, Ethel Siris, Philippe Orcel, Jacques P Brown, Ranuccio Nuti, Pasquale Strazzullo, Maria Serena Benassi, M Leonor Cancela, Laetitia Michou, Domenico Rendina, Luigi Gennari, Fernando Gianfrancesco

Journal: Am. J. Hum. Genet.. 2016 Feb;98(2):275-86.

 

Paget disease of bone (PDB) is a skeletal disorder characterized by focal abnormalities of bone remodeling, which result in enlarged and deformed bones in one or more regions of the skeleton. In some cases, the pagetic tissue undergoes neoplastic transformation, resulting in osteosarcoma ...

Last Updated: 6 Feb 2016

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The effect of Paget disease on axillary lymph node metastases and survival in invasive ductal carcinoma.
 

Author(s): Stephanie M Wong, Rachel A Freedman, Yasuaki Sagara, Emily F Stamell, Stephen D Desantis, William T Barry, Mehra Golshan

Journal: Cancer. 2015 Dec;121(24):4333-40.

 

The objective of this study was to examine the effect of Paget disease (PD) on axillary lymph node metastases and survival in patients who had concomitant invasive ductal carcinoma (PD-IDC).

Last Updated: 5 Dec 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Paget Disease" returned 11 free, full-text review articles on human participants. First 3 results:

Paget disease of the vulva.
 

Author(s): M van der Linden, K A P Meeuwis, J Bulten, T Bosse, M I E van Poelgeest, J A de Hullu

Journal: Crit. Rev. Oncol. Hematol.. 2016 May;101():60-74.

 

In this review, we provide an overview of the clinical aspects, histopathology, molecular genetics, and treatment options for Vulvar Paget's Disease (VPD), a rare skin disease, most commonly found in postmenopausal Caucasian women. The underlying cause of VPD remains not well understood. ...

Last Updated: 23 Apr 2016

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Auricular ossification: A newly recognized feature of osteoprotegerin-deficiency juvenile Paget disease.
 

Author(s): Gary S Gottesman, Katherine L Madson, William H McAlister, Angela Nenninger, Deborah Wenkert, Steven Mumm, Michael P Whyte

Journal: Am. J. Med. Genet. A. 2016 Apr;170A(4):978-85.

 

We report auricular ossification (AO) affecting the elastic cartilage of the ear as a newly recognized feature of osteoprotegerin (OPG)-deficiency juvenile Paget disease (JPD). AO and auricular calcification refer interchangeably to rigid pinnae, sparing the ear lobe, from various ...

Last Updated: 22 Mar 2016

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A clinical series and literature review of the management of inguinal nodal metastases in patients with primary extramammary Paget disease of the scrotum.
 

Author(s): Ye Xin Koh, Timothy Kwang Yong Tay, Sheng Xu, Chee Meng Lee, Melissa Ching Ching Teo

Journal: Asian J Surg. 2015 Jan;38(1):40-6.

 

We describe a series of five patients with extramammary Paget disease of the scrotum with inguinal nodal metastases. These patients underwent combined groin dissection. All patients experienced invasion to the dermis. One patient had invasion of the dartos muscle, another had tumor ...

Last Updated: 2 Jan 2015

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Pathophysiology of Paget's Disease of Bone
 

Status: Recruiting

Condition Summary: Paget's Disease of Bone

 

Last Updated: 15 Jun 2016

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Characterization of Inclusion Body Myopathy Associated With Paget's Disease of Bone and Frontotemporal Dementia (IBMPFD)
 

Status: Recruiting

Condition Summary: Inclusion Body Myopathy With Early-onset Paget Disease and Frontotemporal Dementia; Paget Disease of Bone; Frontotemporal Dementia; Myopathy

 

Last Updated: 12 May 2011

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Characterization of Familial Myopathy and Paget Disease of Bone
 

Status: Recruiting

Condition Summary: Muscle Disorder; Bone Disorder

 

Last Updated: 8 Feb 2017

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