Ovarian small cell carcinoma

Common Name(s)

Ovarian small cell carcinoma

Ovarian small cell carcinoma is a rare type of cancer of the ovaries that primarily affects young women. Carcinoma is a cancer that affects the cells that line organs in the body; these cells are called epithelial cells. People with ovarian small cell carcinoma often have high calcium levels in their blood (hypercalcemia). This situation can be dangerous because the calcium levels will be low in the bones and can affect the heart and brain. Cancer can be very dangerous, and early diagnosis is very important.

The symptoms include stomach bloating, abdominal pain, difficulty eating, feeling full quickly, frequent urination, or sudden, urgent need for urination. Additionally, affected individuals may experience fatigue, indigestion, back pain, constipation, or menstruation irregularities. A history of cancer in your family may increase your risk of developing ovarian small cell carcinoma. The presence of a change (mutation) in the BRCA genes may also increase your risk of ovarian or breast cancer.

In order to diagnose ovarian small cell carcinoma, a doctor may begin by performing a physical pelvic or rectal exam. They may also use blood tests and a vaginal ultrasound to help in diagnosis. The first step for treatment may be surgery to remove as much of the mass as possible. Treatment options may vary between individuals so it is important to talk to your doctor about which treatments are right for you. Support groups are also a good source of information and support for people or families with ovarian small cell carcinoma.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Ovarian small cell carcinoma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Ovarian small cell carcinoma" returned 10 free, full-text research articles on human participants. First 3 results:

Germline SMARCA4 mutations in patients with ovarian small cell carcinoma of hypercalcemic type.
 

Author(s): Joanna Moes-Sosnowska, Lukasz Szafron, Dorota Nowakowska, Agnieszka Dansonka-Mieszkowska, Agnieszka Budzilowska, Bozena Konopka, Joanna Plisiecka-Halasa, Agnieszka Podgorska, Iwona K Rzepecka, Jolanta Kupryjanczyk

Journal:

 

SMARCA4 mutations have recently been identified as driving lesions of the ovarian small cell carcinoma of hypercalcemic type (SCCHT). Familial occurrence of this neoplasm was described previously.

Last Updated: 18 Apr 2015

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Squamous cell carcinoma arising from ovarian mature cystic teratoma and causing small bowel obstruction.
 

Author(s): Hooman Yarmohammadi, Bahar Mansoori, Vince Wong, Vania Tacher, Luke R Wilkins, Peter G Pavlidakey, John R Haaga

Journal: J Cancer Res Ther. ;10(3):770-2.

 

Malignant transformation of mature cystic teratoma (MCT) is a rare phenomenon with incidence of approximately 1-3%. We report a 48-year-old woman who presented to the emergency room with symptoms of bowel obstruction. She underwent computed tomography scan for the evaluation of obstruction, ...

Last Updated: 15 Oct 2014

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Small cell ovarian carcinoma: genomic stability and responsiveness to therapeutics.
 

Author(s): Lisa F Gamwell, Karen Gambaro, Maria Merziotis, Colleen Crane, Suzanna L Arcand, Valerie Bourada, Christopher Davis, Jeremy A Squire, David G Huntsman, Patricia N Tonin, Barbara C Vanderhyden

Journal:

 

The biology of small cell ovarian carcinoma of the hypercalcemic type (SCCOHT), which is a rare and aggressive form of ovarian cancer, is poorly understood. Tumourigenicity, in vitro growth characteristics, genetic and genomic anomalies, and sensitivity to standard and novel chemotherapeutic ...

Last Updated: 26 Apr 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Ovarian small cell carcinoma" returned 0 free, full-text review articles on human participants.

 
 
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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

International Ovarian & Testicular Stromal Tumor Registry
 

Status: Recruiting

Condition Summary: Ovarian Stromal Tumor; Testicular Stromal Tumors; Ovarian Small Cell Carcinoma

 

Last Updated: 16 Oct 2015

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Talazoparib in Treating Patients With Advanced or Metastatic Solid Tumors That Cannot Be Removed by Surgery and Liver or Kidney Dysfunction
 

Status: Not yet recruiting

Condition Summary: Estrogen Receptor Negative; Head and Neck Squamous Cell Carcinoma; HER2/Neu Negative; Hormone-Resistant Prostate Cancer; Metastatic Pancreatic Adenocarcinoma; Progesterone Receptor Negative; Solid Neoplasm; Stage III Mesothelioma; Stage IIIA Gastric Cancer; Stage IIIA Non-Small Cell Lung Cancer; Stage IIIA Ovarian Cancer; Stage IIIA Small Cell Lung Carcinoma; Stage IIIB Gastric Cancer; Stage IIIB Non-Small Cell Lung Cancer; Stage IIIB Ovarian Cancer; Stage IIIB Small Cell Lung Carcinoma; Stage IIIC Gastric Cancer; Stage IIIC Ovarian Cancer; Stage IV Mesothelioma; Stage IV Non-Small Cell Lung Cancer; Stage IV Ovarian Cancer; Stage IV Small Cell Lung Carcinoma; Triple-Negative Breast Carcinoma

 

Last Updated: 2 Oct 2015

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Trial of Topotecan With VX-970, an ATR Kinase Inhibitor, in Small Cell Lung Cancer
 

Status: Recruiting

Condition Summary: Carcinoma, Non-Small -Cell Lung; Ovarian Neoplasms; Small Cell Lung Carcinoma; Uterine Cervical Neoplasms; Carcinoma, Neuroendocrine

 

Last Updated: 24 Jul 2015

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