Ovarian epithelial cancer

Common Name(s)

Ovarian epithelial cancer

Ovarian cancer, the leading cause of death from gynecologic malignancy, is characterized by advanced presentation with loco-regional dissemination in the peritoneal cavity and the rare incidence of visceral metastases ({6:Chi et al., 2001}). These typical features relate to the biology of the disease, which is a principal determinant of outcome ({1:Auersperg et al., 2001}). Epithelial ovarian cancer is the most common form and encompasses 5 major histologic subtypes: papillary serous, endometrioid, mucinous, clear cell, and transitional cell. Epithelial ovarian cancer arises as a result of genetic alterations sustained by the ovarian surface epithelium ({45:Stany et al., 2008}; {44:Soslow, 2008}).
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Ovarian epithelial cancer" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Ovarian epithelial cancer" returned 957 free, full-text research articles on human participants. First 3 results:

Overexpression of microRNA-196b Accelerates Invasiveness of Cancer Cells in Recurrent Epithelial Ovarian Cancer Through Regulation of Homeobox A9.
 

Author(s): Gun Oh Chong, Hyo-Sung Jeon, Hyung Soo Han, Ji Woong Son, Yoon Hee Lee, Dae Gy Hong, Hong Jun Park, Yoon Soon Lee, Young Lae Cho

Journal: Cancer Genomics Proteomics. ;14(2):137-141.

 

Although microRNAs (miRNAs) are known to influence messenger RNA post-transcriptional control and contribute to human tumorigenesis, little is known about the differences in miRNA expression between primary and recurrent epithelial ovarian cancer (EOC). The purpose of this study was ...

Last Updated: 7 Apr 2017

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Let-7e sensitizes epithelial ovarian cancer to cisplatin through repressing DNA double strand break repair.
 

Author(s): Man Xiao, Jing Cai, Liqiong Cai, Jinghui Jia, Lisha Xie, Ying Zhu, Bangxing Huang, Dongdong Jin, Zehua Wang

Journal:

 

Resistance to platinum-based chemotherapy remains a great challenge for ovarian cancer treatment. The human let-7 family contains 13 members located on nine different chromosomes, and most members have been implicated in the modulation of drug sensitivity in cancers. Our previous ...

Last Updated: 5 Apr 2017

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Does serum CA125 have clinical value for follow-up monitoring of postoperative patients with epithelial ovarian cancer? Results of a 12-year study.
 

Author(s): Na Guo, Zhilan Peng

Journal:

 

The detection of CA125 has been used in the follow up of ovarian cancer. At present, some scholars believe that serum CA125 has no clinical value for the follow-up monitoring the recurrence for postoperative patients with epithelial ovarian cancer, but in our clinical follow-up found ...

Last Updated: 12 Mar 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Ovarian epithelial cancer" returned 93 free, full-text review articles on human participants. First 3 results:

Role of Nerve Growth Factor (NGF) and miRNAs in Epithelial Ovarian Cancer.
 

Author(s): Rocío Retamales-Ortega, Lorena Oróstica, Carolina Vera, Paula Cuevas, Andrea Hernández, Iván Hurtado, Margarita Vega, Carmen Romero

Journal:

 

Ovarian cancer is the eighth most common cancer in women worldwide, and epithelial ovarian cancer (EOC) represents 90% of cases. Nerve growth factor (NGF) and its high affinity receptor tyrosine kinase A receptor (TRKA) have been associated with the development of several types of ...

Last Updated: 1 Mar 2017

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Molecular Characterization of Epithelial Ovarian Cancer: Implications for Diagnosis and Treatment.
 

Author(s): Veronica Rojas, Kim M Hirshfield, Shridar Ganesan, Lorna Rodriguez-Rodriguez

Journal:

 

Epithelial ovarian cancer is a highly heterogeneous disease characterized by multiple histological subtypes. Molecular diversity has been shown to occur within specific histological subtypes of epithelial ovarian cancer, between different tumors of an individual patient, as well as ...

Last Updated: 16 Dec 2016

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The Effect of Breastfeeding Duration and Parity on the Risk of Epithelial Ovarian Cancer: A Systematic Review and Meta-analysis.
 

Author(s): Ho Kyung Sung, Seung Hyun Ma, Ji-Yeob Choi, Yunji Hwang, Choonghyun Ahn, Byoung-Gie Kim, Yong-Man Kim, Jae Weon Kim, Sokbom Kang, Jaehoon Kim, Tae Jin Kim, Keun-Young Yoo, Daehee Kang, Suekyung Park

Journal: J Prev Med Public Health. 2016 Nov;49(6):349-366.

 

We conducted a systematic review and meta-analysis to summarize current evidence regarding the association of parity and duration of breastfeeding with the risk of epithelial ovarian cancer (EOC).

Last Updated: 13 Dec 2016

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Optimisation of Disease Management in Patients With Epithelial Ovarian Cancer in France
 

Status: Not yet recruiting

Condition Summary: Ovarian Epithelial Cancer

 

Last Updated: 5 Dec 2016

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Last Updated: 24 Apr 2017

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p53 Gene in Treatment of Recurrent Ovarian Epithelial Cancer, Fallopian Tube Cancer, and Primary Peritoneal Cancer
 

Status: Not yet recruiting

Condition Summary: Ovarian Epithelial Cancer; Fallopian Tube Cancer; Primary Peritoneal Cancer

 

Last Updated: 30 Apr 2015

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