Ovarian epithelial cancer

Common Name(s)

Ovarian epithelial cancer

Ovarian cancer, the leading cause of death from gynecologic malignancy, is characterized by advanced presentation with loco-regional dissemination in the peritoneal cavity and the rare incidence of visceral metastases ({6:Chi et al., 2001}). These typical features relate to the biology of the disease, which is a principal determinant of outcome ({1:Auersperg et al., 2001}). Epithelial ovarian cancer is the most common form and encompasses 5 major histologic subtypes: papillary serous, endometrioid, mucinous, clear cell, and transitional cell. Epithelial ovarian cancer arises as a result of genetic alterations sustained by the ovarian surface epithelium ({45:Stany et al., 2008}; {44:Soslow, 2008}).
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Ovarian epithelial cancer" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Ovarian epithelial cancer" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Ovarian epithelial cancer" returned 757 free, full-text research articles on human participants. First 3 results:

Local estrogen metabolism in epithelial ovarian cancer suggests novel targets for therapy.
 

Author(s): Xia Ren, Xuan Wu, Stephen G Hillier, K Scott Fegan, Hilary O D Critchley, J Ian Mason, Sana Sarvi, Christopher R Harlow

Journal: J. Steroid Biochem. Mol. Biol.. 2015 Jun;150():54-63.

 

Epithelial ovarian cancer (EOC) accounts for about 90% of malignant ovarian tumors, and estrogen is often implicated in disease progression. We therefore compared the potential for gating of estrogen action via pre-receptor metabolism in normal human ovarian surface epithelium (OSE), ...

Last Updated: 7 May 2015

Go To URL
Overexpression of JARID1B is associated with poor prognosis and chemotherapy resistance in epithelial ovarian cancer.
 

Author(s): Lishuang Wang, Yuanfu Mao, Guiqin Du, Chunbo He, Shiyu Han

Journal: Tumour Biol.. 2015 Apr;36(4):2465-72.

 

JARID1B, a histone demethylase, has been reported to be highly expressed in various human cancers. In the present study, we investigated the association of JARID1B level with epithelial ovarian cancer (EOC) and prognosis of patients with EOC. We analyzed JARID1B expression in 20 normal ...

Last Updated: 16 Apr 2015

Go To URL
Low-dose-intensity bevacizumab with weekly irinotecan for platinum- and taxanes-resistant epithelial ovarian cancer.
 

Author(s): Ying Liu, Zhonghai Ren, Shuning Xu, Hua Bai, Ning Ma, Feng Wang

Journal: Cancer Chemother. Pharmacol.. 2015 Mar;75(3):645-51.

 

The purpose of this study was to evaluate the safety and efficacy of low-dose-intensity bevacizumab and weekly irinotecan as salvage treatment for patients with platinum- and taxanes-resistant advanced epithelial ovarian cancer.

Last Updated: 26 Feb 2015

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Ovarian epithelial cancer" returned 67 free, full-text review articles on human participants. First 3 results:

Suppression of epithelial ovarian cancer invasion into the omentum by 1α,25-dihydroxyvitamin D3 and its receptor.
 

Author(s): Panida Lungchukiet, Yuefeng Sun, Ravi Kasiappan, Waise Quarni, Santo V Nicosia, Xiaohong Zhang, Wenlong Bai

Journal: J. Steroid Biochem. Mol. Biol.. 2015 Apr;148():138-47.

 

Epithelial ovarian cancer (EOC) is the leading cause of gynecological cancer death in women, mainly because it has spread to intraperitoneal tissues such as the omentum in the peritoneal cavity by the time of diagnosis. In the present study, we established in vitro assays, ex vivo ...

Last Updated: 16 Mar 2015

Go To URL
Potential application of curcumin and its analogues in the treatment strategy of patients with primary epithelial ovarian cancer.
 

Author(s): Katarzyna M Terlikowska, Anna M Witkowska, Malgorzata E Zujko, Bozena Dobrzycka, Slawomir J Terlikowski

Journal:

 

Recent findings on the molecular basis of ovarian cancer development and progression create new opportunities to develop anticancer medications that would affect specific metabolic pathways and decrease side systemic toxicity of conventional treatment. Among new possibilities for ...

Last Updated: 28 Nov 2014

Go To URL
Role of nerve growth factor and its TRKA receptor in normal ovarian and epithelial ovarian cancer angiogenesis.
 

Author(s): Carolina Vera, Verónica Tapia, Margarita Vega, Carmen Romero

Journal:

 

In normal ovarian function a controlled angiogenesis is essential. Several growth factors are involved in this process, such as the vascular endothelial growth factor (VEGF) and nerve growth factor (NGF). The angiogenesis process in the normal ovary is a tightly controlled process ...

Last Updated: 10 Oct 2014

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

p53 Gene in Treatment of Recurrent Ovarian Epithelial Cancer, Fallopian Tube Cancer, and Primary Peritoneal Cancer
 

Status: Not yet recruiting

Condition Summary: Ovarian Epithelial Cancer; Fallopian Tube Cancer; Primary Peritoneal Cancer

 

Last Updated: 30 Apr 2015

Go to URL
Phase II Study DCVAC/OvCa Added to First Line Carboplatin and Paclitaxel Newly Diagnosed Epithelial Ovarian Carcinoma
 

Status: Recruiting

Condition Summary: Ovarian Neoplasms; Ovarian Epithelial Cancer

 

Last Updated: 19 May 2015

Go to URL
Survivorship Care Planning in Improving Quality of Life in Survivors of Ovarian Cancer
 

Status: Recruiting

Condition Summary: Cancer Survivor; Stage IA Ovarian Epithelial Cancer; Stage IB Ovarian Epithelial Cancer; Stage IC Ovarian Epithelial Cancer; Stage IIA Ovarian Epithelial Cancer; Stage IIB Ovarian Epithelial Cancer; Stage IIC Ovarian Epithelial Cancer; Stage IIIA Ovarian Epithelial Cancer; Stage IIIB Ovarian Epithelial Cancer; Stage IIIC Ovarian Epithelial Cancer

 

Last Updated: 18 Mar 2015

Go to URL