Ovarian epithelial cancer

Common Name(s)

Ovarian epithelial cancer

Ovarian cancer, the leading cause of death from gynecologic malignancy, is characterized by advanced presentation with loco-regional dissemination in the peritoneal cavity and the rare incidence of visceral metastases ({6:Chi et al., 2001}). These typical features relate to the biology of the disease, which is a principal determinant of outcome ({1:Auersperg et al., 2001}). Epithelial ovarian cancer is the most common form and encompasses 5 major histologic subtypes: papillary serous, endometrioid, mucinous, clear cell, and transitional cell. Epithelial ovarian cancer arises as a result of genetic alterations sustained by the ovarian surface epithelium ({45:Stany et al., 2008}; {44:Soslow, 2008}).
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Ovarian epithelial cancer" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Ovarian epithelial cancer" returned 1062 free, full-text research articles on human participants. First 3 results:

MiR-628-5p decreases the tumorigenicity of epithelial ovarian cancer cells by targeting at FGFR2.
 

Author(s): Ming Li, Zhimin Qian, Xiaoling Ma, Xiaolong Lin, Yanan You, Yiying Li, Tong Chen, Hua Jiang

Journal: Biochem. Biophys. Res. Commun.. 2018 01;495(2):2085-2091.

 

Micro RNAs (miRNAs) are small non-coding RNAs which are 19-24 nucleotides in length. MiRNAs play a vital role in the whole process of tumour development, but how they influence the tumourigenecity of epithelial ovarian cancer (EOC)cells is rarely researched. In our study, it was verified ...

Last Updated: 31 Dec 1969

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Hormone-receptor expression status of epithelial ovarian cancer in Ibadan, South-western Nigeria.
 

Author(s): Mustapha Akanji Ajani, Ayodeji Salami, Olutosin Alaba Awolude, Abideen Olayiwola Oluwasola

Journal:

 

Epidemiological evidence strongly suggests that steroid hormones are implicated in the pathogenesis of ovarian cancer. Estrogen receptor (ER) and Progesterone receptor (PR) are prognostic indicators for a number of epithelial tumors and may play the same role in ovarian cancers. This ...

Last Updated: 31 Dec 1969

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Snail Driving Alternative Splicing of CD44 by ESRP1 Enhances Invasion and Migration in Epithelial Ovarian Cancer.
 

Author(s): Le Chen, Ying Yao, Lijuan Sun, Jiajia Zhou, Minmin Miao, Shujuan Luo, Guanming Deng, Junjun Li, Jing Wang, Jie Tang

Journal: Cell. Physiol. Biochem.. 2017 ;43(6):2489-2504.

 

Our study aims to investigate the role, effect and mechanisms of ESRP1 (epithelial splicing regulatory protein 1) in epithelial-mesenchymal transition (EMT) in epithelial ovarian cancer (EOC).

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Ovarian epithelial cancer" returned 100 free, full-text review articles on human participants. First 3 results:

Missed therapeutic and prevention opportunities in women with BRCA-mutated epithelial ovarian cancer and their families due to low referral rates for genetic counseling and BRCA testing: A review of the literature.
 

Author(s): Paul J Hoskins, Walter H Gotlieb

Journal: CA Cancer J Clin. 2017 Nov;67(6):493-506.

 

Answer questions and earn CME/CNE Fifteen percent of women with epithelial ovarian cancer have inherited mutations in the BRCA breast cancer susceptibility genes. Knowledge of her BRCA status has value both for the woman and for her family. A therapeutic benefit exists for the woman ...

Last Updated: 31 Dec 1969

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The Functions of MicroRNA-200 Family in Ovarian Cancer: Beyond Epithelial-Mesenchymal Transition.
 

Author(s): Pui-Wah Choi, Shu-Wing Ng

Journal:

 

The majority of studies on microRNA-200 family members (miR-200s) in human cancers are based on the premise that miR-200s maintain epithelial cell integrity by suppressing epithelial-mesenchymal transition (EMT) through direct inhibition of mesenchymal transcription factors zinc finger ...

Last Updated: 31 Dec 1969

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Role of Nerve Growth Factor (NGF) and miRNAs in Epithelial Ovarian Cancer.
 

Author(s): Rocío Retamales-Ortega, Lorena Oróstica, Carolina Vera, Paula Cuevas, Andrea Hernández, Iván Hurtado, Margarita Vega, Carmen Romero

Journal:

 

Ovarian cancer is the eighth most common cancer in women worldwide, and epithelial ovarian cancer (EOC) represents 90% of cases. Nerve growth factor (NGF) and its high affinity receptor tyrosine kinase A receptor (TRKA) have been associated with the development of several types of ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Cytoreductive Surgery and HIPEC in First or Secondary Platinum-resistant Recurrent Ovarian Epithelial Cancer
 

Status: Not yet recruiting

Condition Summary: Ovarian Epithelial Cancer

 

Last Updated: 17 Jul 2017

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Optimisation of Disease Management in Patients With Epithelial Ovarian Cancer in France
 

Status: Not yet recruiting

Condition Summary: Ovarian Epithelial Cancer

 

Last Updated: 5 Dec 2016

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Last Updated: 15 Jun 2017

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