Ovarian epithelial cancer

Common Name(s)

Ovarian epithelial cancer

Ovarian cancer, the leading cause of death from gynecologic malignancy, is characterized by advanced presentation with loco-regional dissemination in the peritoneal cavity and the rare incidence of visceral metastases ({6:Chi et al., 2001}). These typical features relate to the biology of the disease, which is a principal determinant of outcome ({1:Auersperg et al., 2001}). Epithelial ovarian cancer is the most common form and encompasses 5 major histologic subtypes: papillary serous, endometrioid, mucinous, clear cell, and transitional cell. Epithelial ovarian cancer arises as a result of genetic alterations sustained by the ovarian surface epithelium ({45:Stany et al., 2008}; {44:Soslow, 2008}).
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Ovarian epithelial cancer" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Ovarian epithelial cancer" returned 749 free, full-text research articles on human participants. First 3 results:

Low-dose-intensity bevacizumab with weekly irinotecan for platinum- and taxanes-resistant epithelial ovarian cancer.
 

Author(s): Ying Liu, Zhonghai Ren, Shuning Xu, Hua Bai, Ning Ma, Feng Wang

Journal: Cancer Chemother. Pharmacol.. 2015 Mar;75(3):645-51.

 

The purpose of this study was to evaluate the safety and efficacy of low-dose-intensity bevacizumab and weekly irinotecan as salvage treatment for patients with platinum- and taxanes-resistant advanced epithelial ovarian cancer.

Last Updated: 26 Feb 2015

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A cost-effectiveness analysis of a chemoresponse assay for treatment of patients with recurrent epithelial ovarian cancer.
 

Author(s): Victoria Plamadeala, Joseph L Kelley, John K Chan, Thomas C Krivak, Michael J Gabrin, Stacey L Brower, Matthew A Powell, Thomas J Rutherford, Robert L Coleman

Journal: Gynecol. Oncol.. 2015 Jan;136(1):94-8.

 

Clinical validation of a chemoresponse assay was recently published, demonstrating a significant increase in overall survival in recurrent ovarian cancer patients treated with therapies to which their tumor was sensitive in the assay. The current study investigates the cost effectiveness ...

Last Updated: 2 Jan 2015

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Systematic lymphadenectomy in the treatment of epithelial ovarian cancer: a meta-analysis of multiple epidemiology studies.
 

Author(s): Jingwei Gao, Xiaoqing Yang, Yuquan Zhang

Journal: Jpn. J. Clin. Oncol.. 2015 Jan;45(1):49-60.

 

To evaluate the role of systematic lymphadenectomy in epithelial ovarian cancer by comparing 5-year overall survival rates between systematic and unsystematic lymphadenectomies.

Last Updated: 27 Dec 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Ovarian epithelial cancer" returned 66 free, full-text review articles on human participants. First 3 results:

Suppression of epithelial ovarian cancer invasion into the omentum by 1α,25-dihydroxyvitamin D3 and its receptor.
 

Author(s): Panida Lungchukiet, Yuefeng Sun, Ravi Kasiappan, Waise Quarni, Santo V Nicosia, Xiaohong Zhang, Wenlong Bai

Journal: J. Steroid Biochem. Mol. Biol.. 2015 Apr;148():138-47.

 

Epithelial ovarian cancer (EOC) is the leading cause of gynecological cancer death in women, mainly because it has spread to intraperitoneal tissues such as the omentum in the peritoneal cavity by the time of diagnosis. In the present study, we established in vitro assays, ex vivo ...

Last Updated: 16 Mar 2015

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Role of nerve growth factor and its TRKA receptor in normal ovarian and epithelial ovarian cancer angiogenesis.
 

Author(s): Carolina Vera, Verónica Tapia, Margarita Vega, Carmen Romero

Journal:

 

In normal ovarian function a controlled angiogenesis is essential. Several growth factors are involved in this process, such as the vascular endothelial growth factor (VEGF) and nerve growth factor (NGF). The angiogenesis process in the normal ovary is a tightly controlled process ...

Last Updated: 10 Oct 2014

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Fertility sparing surgery in early stage epithelial ovarian cancer.
 

Author(s): Antonino Ditto, Fabio Martinelli, Domenica Lorusso, Edward Haeusler, Marialuisa Carcangiu, Francesco Raspagliesi

Journal: J Gynecol Oncol. 2014 Oct;25(4):320-7.

 

Fertility sparing surgery (FSS) is a strategy often considered in young patients with early epithelial ovarian cancer. We investigated the role and the outcomes of FSS in eEOC patients who underwent comprehensive surgery.

Last Updated: 14 Oct 2014

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

p53 Gene in Treatment of Recurrent Ovarian Epithelial Cancer, Fallopian Tube Cancer, and Primary Peritoneal Cancer
 

Status: Not yet recruiting

Condition Summary: Ovarian Epithelial Cancer; Fallopian Tube Cancer; Primary Peritoneal Cancer

 

Last Updated: 30 Apr 2015

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Phase II Study DCVAC/OvCa Added to First Line Carboplatin and Paclitaxel Newly Diagnosed Epithelial Ovarian Carcinoma
 

Status: Recruiting

Condition Summary: Ovarian Neoplasms; Ovarian Epithelial Cancer

 

Last Updated: 19 May 2015

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Survivorship Care Planning in Improving Quality of Life in Survivors of Ovarian Cancer
 

Status: Recruiting

Condition Summary: Cancer Survivor; Stage IA Ovarian Epithelial Cancer; Stage IB Ovarian Epithelial Cancer; Stage IC Ovarian Epithelial Cancer; Stage IIA Ovarian Epithelial Cancer; Stage IIB Ovarian Epithelial Cancer; Stage IIC Ovarian Epithelial Cancer; Stage IIIA Ovarian Epithelial Cancer; Stage IIIB Ovarian Epithelial Cancer; Stage IIIC Ovarian Epithelial Cancer

 

Last Updated: 18 Mar 2015

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