Ovarian epithelial cancer

Common Name(s)

Ovarian epithelial cancer

Ovarian cancer, the leading cause of death from gynecologic malignancy, is characterized by advanced presentation with loco-regional dissemination in the peritoneal cavity and the rare incidence of visceral metastases ({6:Chi et al., 2001}). These typical features relate to the biology of the disease, which is a principal determinant of outcome ({1:Auersperg et al., 2001}). Epithelial ovarian cancer is the most common form and encompasses 5 major histologic subtypes: papillary serous, endometrioid, mucinous, clear cell, and transitional cell. Epithelial ovarian cancer arises as a result of genetic alterations sustained by the ovarian surface epithelium ({45:Stany et al., 2008}; {44:Soslow, 2008}).
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Ovarian epithelial cancer" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Ovarian epithelial cancer" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Ovarian epithelial cancer" returned 1148 free, full-text research articles on human participants. First 3 results:

Expression of resistance gene and prognosis of chemotherapy in primary epithelial ovarian cancer.
 

Author(s): Fengmei Yang, Bo Gao, Wei Chen, Enfu Du, Yong Liang, Xiuxue Hu, Xiaofeng Yang

Journal: Medicine (Baltimore). 2018 Oct;97(41):e12364.

 

The sensitivity of tumor cells to chemotherapy drugs may become attenuated accounts for various reasons. Reduced drug sensitivity may cause the failure of chemotherapy and affect the prognosis of patients with cancer. This study investigates the relationship between the expression ...

Last Updated: 31 Dec 1969

Go To URL
FSCN1 Promotes Epithelial-Mesenchymal Transition Through Increasing Snail1 in Ovarian Cancer Cells.
 

Author(s): Jie Li, Songlin Zhang, Meili Pei, Lei Wu, Yanli Liu, Huijin Li, Jiaojiao Lu, Xu Li

Journal: Cell. Physiol. Biochem.. 2018 ;49(5):1766-1777.

 

Epithelial-mesenchymal transition (EMT) is one of the key mechanisms mediating cancer progression. Snail1 has a pivotal role in the regulation of EMT, involving the loss of E-cadherin and concomitant upregulation of vimentin, among other biomarkers. We have found FSCN1 promoted EMT ...

Last Updated: 31 Dec 1969

Go To URL
LncRNA TUG1 promotes cells proliferation and inhibits cells apoptosis through regulating AURKA in epithelial ovarian cancer cells.
 

Author(s): Tonghuai Li, Yan Chen, Jingjing Zhang, Shaoxiao Liu

Journal: Medicine (Baltimore). 2018 Sep;97(36):e12131.

 

This study aimed to assess the effect of long noncoding RNAs (lncRNAs) taurine-upregulated gene 1 (TUG1) on cells proliferation and apoptosis as well as its targeting genes in epithelial ovarian cancer (EOC) cells.Blank mimic, lncRNA TUG1 mimic, blank inhibitor, and lncRNA TUG1 inhibitor ...

Last Updated: 31 Dec 1969

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Ovarian epithelial cancer" returned 102 free, full-text review articles on human participants. First 3 results:

One-Carbon Metabolism: Biological Players in Epithelial Ovarian Cancer.
 

Author(s): Andrea Rizzo, Alessandra Napoli, Francesca Roggiani, Antonella Tomassetti, Marina Bagnoli, Delia Mezzanzanica

Journal:

 

Metabolism is deeply involved in cell behavior and homeostasis maintenance, with metabolites acting as molecular intermediates to modulate cellular functions. In particular, one-carbon metabolism is a key biochemical pathway necessary to provide carbon units required for critical ...

Last Updated: 31 Dec 1969

Go To URL
Molecular diagnosis in type I epithelial ovarian cancer.
 

Author(s): Paweł Sadłecki, Małgorzata Walentowicz-Sadłecka, Marek Grabiec

Journal: Ginekol. Pol.. 2017 ;88(12):692-697.

 

The term epithelial ovarian cancer (EOC) refers to a heterogeneous group of tumors, including serous, mucinous, endometrioid and clear cell carcinomas, each characterized by specific molecular background and clinical outcome. A growing body of evidence suggests that molecular pathogenesis ...

Last Updated: 31 Dec 1969

Go To URL
Emerging Therapeutics to Overcome Chemoresistance in Epithelial Ovarian Cancer: A Mini-Review.
 

Author(s): Robert Cornelison, Danielle C Llaneza, Charles N Landen

Journal:

 

Ovarian cancer is the fifth leading cause of cancer death among women and the most lethal gynecologic malignancy. One of the leading causes of death in high-grade serous ovarian cancer (HGSOC) is chemoresistant disease, which may present as intrinsic or acquired resistance to therapies. ...

Last Updated: 31 Dec 1969

Go To URL
 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Cytoreductive Surgery and HIPEC in First or Secondary Platinum-resistant Recurrent Ovarian Epithelial Cancer
 

Status: Not yet recruiting

Condition Summary: Ovarian Epithelial Cancer

 

Last Updated: 17 Jul 2017

Go to URL

Last Updated: 11 Oct 2018

Go to URL

Last Updated: 1 Mar 2018

Go to URL