Ovarian epithelial cancer

Common Name(s)

Ovarian epithelial cancer

Ovarian cancer, the leading cause of death from gynecologic malignancy, is characterized by advanced presentation with loco-regional dissemination in the peritoneal cavity and the rare incidence of visceral metastases ({6:Chi et al., 2001}). These typical features relate to the biology of the disease, which is a principal determinant of outcome ({1:Auersperg et al., 2001}). Epithelial ovarian cancer is the most common form and encompasses 5 major histologic subtypes: papillary serous, endometrioid, mucinous, clear cell, and transitional cell. Epithelial ovarian cancer arises as a result of genetic alterations sustained by the ovarian surface epithelium ({45:Stany et al., 2008}; {44:Soslow, 2008}).
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Ovarian epithelial cancer" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Ovarian epithelial cancer" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Ovarian epithelial cancer" returned 940 free, full-text research articles on human participants. First 3 results:

TP53 mutation-mediated genomic instability induces the evolution of chemoresistance and recurrence in epithelial ovarian cancer.
 

Author(s): Meiying Zhang, Guanglei Zhuang, Xiangjun Sun, Yanying Shen, Wenjing Wang, Qing Li, Wen Di

Journal:

 

Genomic instability caused by mutation of the checkpoint molecule TP53 may endow cancer cells with the ability to undergo genomic evolution to survive stress and treatment. We attempted to gain insight into the potential contribution of ovarian cancer genomic instability resulted ...

Last Updated: 2 Feb 2017

Go To URL
Emodin Inhibits the Epithelial to Mesenchymal Transition of Epithelial Ovarian Cancer Cells via ILK/GSK-3β/Slug Signaling Pathway.
 

Author(s): Jingjing Lu, Ying Xu, Xuan Wei, Zhe Zhao, Jing Xue, Peishu Liu

Journal: Biomed Res Int. 2016 ;2016():6253280.

 

Epithelial ovarian cancer (EOC) is the most lethal gynecologic malignancy. Despite the anticancer capabilities of emodin observed in many cancers, including EOC, the underlying molecular mechanism remains to be elucidated. A crucial link has been discovered between the acquisition ...

Last Updated: 18 Jan 2017

Go To URL
Effects of sequential paclitaxel-carboplatin followed by gemcitabine-based chemotherapy compared with paclitaxel-carboplatin therapy administered to patients with advanced epithelial ovarian cancer: A retrospective, STROBE-compliant study.
 

Author(s): Fei Wang, Xuelian Du, Xiaoxia Li, Naifu Liu, Hao Yu, Xiugui Sheng

Journal: Medicine (Baltimore). 2016 Dec;95(51):e5696.

 

We aimed to compare the efficacy of paclitaxel and carboplatin followed by gemcitabine-based combination chemotherapy with paclitaxel-carboplatin for treating advanced epithelial ovarian cancer in this retrospective, STROBE-compliant study. Patients' tolerance to treatment was also ...

Last Updated: 21 Dec 2016

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Ovarian epithelial cancer" returned 90 free, full-text review articles on human participants. First 3 results:

Paradigm Shift in the Management Strategy for Epithelial Ovarian Cancer.
 

Author(s): Keiichi Fujiwara, Jessica N McAlpine, Stephanie Lheureux, Noriomi Matsumura, Amit M Oza

Journal: Am Soc Clin Oncol Educ Book. 2016 ;35():e247-57.

 

The hypothesis on the pathogenesis of epithelial ovarian cancer continues to evolve. Although epithelial ovarian cancer had been assumed to arise from the coelomic epithelium of the ovarian surface, it is now becoming clearer that the majority of serous carcinomas arise from epithelium ...

Last Updated: 2 Jun 2016

Go To URL
Update on Intraperitoneal Chemotherapy for the Treatment of Epithelial Ovarian Cancer.
 

Author(s): Charlie Gourley, Joan L Walker, Helen J Mackay

Journal: Am Soc Clin Oncol Educ Book. 2016 ;35():143-51.

 

Surgical treatment and chemotherapy administration in women with epithelial ovarian cancer is more controversial today than at any point in the last 3 decades. The use of chemotherapy administered intraperitoneally has been particularly contentious. Three large randomized phase III ...

Last Updated: 2 Jun 2016

Go To URL
Morphologic, Immunophenotypic, and Molecular Features of Epithelial Ovarian Cancer.
 

Author(s): Preetha Ramalingam

Journal: Oncology (Williston Park, N.Y.). 2016 Feb;30(2):166-76.

 

Epithelial ovarian cancer comprises a heterogeneous group of tumors. The four most common subtypes are serous, endometrioid, clear cell, and mucinous carcinoma. Less common are transitional cell tumors, including transitional cell carcinoma and malignant Brenner tumor. While in the ...

Last Updated: 19 Feb 2016

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Optimisation of Disease Management in Patients With Epithelial Ovarian Cancer in France
 

Status: Not yet recruiting

Condition Summary: Ovarian Epithelial Cancer

 

Last Updated: 5 Dec 2016

Go to URL
p53 Gene in Treatment of Recurrent Ovarian Epithelial Cancer, Fallopian Tube Cancer, and Primary Peritoneal Cancer
 

Status: Not yet recruiting

Condition Summary: Ovarian Epithelial Cancer; Fallopian Tube Cancer; Primary Peritoneal Cancer

 

Last Updated: 30 Apr 2015

Go to URL
Impact of Fas/FasL in Chemotherapy Response in Epithelial Ovarian Carcinoma
 

Status: Recruiting

Condition Summary: Ovarian Carcinoma

 

Last Updated: 16 Aug 2016

Go to URL