Ovarian epithelial cancer

Common Name(s)

Ovarian epithelial cancer

Ovarian cancer, the leading cause of death from gynecologic malignancy, is characterized by advanced presentation with loco-regional dissemination in the peritoneal cavity and the rare incidence of visceral metastases ({6:Chi et al., 2001}). These typical features relate to the biology of the disease, which is a principal determinant of outcome ({1:Auersperg et al., 2001}). Epithelial ovarian cancer is the most common form and encompasses 5 major histologic subtypes: papillary serous, endometrioid, mucinous, clear cell, and transitional cell. Epithelial ovarian cancer arises as a result of genetic alterations sustained by the ovarian surface epithelium ({45:Stany et al., 2008}; {44:Soslow, 2008}).
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Ovarian epithelial cancer" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Ovarian epithelial cancer" returned 948 free, full-text research articles on human participants. First 3 results:

[Purple-bluish tongue is associated with platelet counts, and the recurrence of epithelial ovarian cancer].
 

Author(s): Jian Hao, Cuihong Zhu, Rui Cao, Xue Yang, Xiuli Ding, Yanan Man, Xiongzhi Wu

Journal: J Tradit Chin Med. 2016 Jun;36(3):321-5.

 

To evaluate the relationship between purple-bluish tongue and platelet counts, and further to examine their associations with the recurrence of epithelial ovarian cancer.

Last Updated: 29 Jul 2016

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TET3 inhibits TGF-β1-induced epithelial-mesenchymal transition by demethylating miR-30d precursor gene in ovarian cancer cells.
 

Author(s): Zhongxue Ye, Jie Li, Xi Han, Huilian Hou, He Chen, Xia Zheng, Jiaojiao Lu, Lijie Wang, Wei Chen, Xu Li, Le Zhao

Journal:

 

Abnormal DNA methylation/demethylation is recognized as a hallmark of cancer. TET (ten-eleven translocation) family members are novel DNA demethylation related proteins that dysregulate in multiple malignances. However, their effects on ovarian cancer remain to be elucidated.

Last Updated: 4 May 2016

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Utility of Serum miR-125b as a Diagnostic and Prognostic Indicator and Its Alliance with a Panel of Tumor Suppressor Genes in Epithelial Ovarian Cancer.
 

Author(s): Mariyam Zuberi, Imran Khan, Rashid Mir, Gauri Gandhi, Prakash Chandra Ray, Alpana Saxena

Journal:

 

MicroRNAs (miRNAs) have been found to be dysregulated in epithelial ovarian cancer (EOC) and may function as either tumor suppressor genes (TSGs) or as oncogenes. Hypermethylation of miRNA silences the tumour suppressive function of a miRNA or hypermethylation of a TSG regulating ...

Last Updated: 20 Apr 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Ovarian epithelial cancer" returned 91 free, full-text review articles on human participants. First 3 results:

Paradigm Shift in the Management Strategy for Epithelial Ovarian Cancer.
 

Author(s): Keiichi Fujiwara, Jessica N McAlpine, Stephanie Lheureux, Noriomi Matsumura, Amit M Oza

Journal: Am Soc Clin Oncol Educ Book. 2016 ;35():e247-57.

 

The hypothesis on the pathogenesis of epithelial ovarian cancer continues to evolve. Although epithelial ovarian cancer had been assumed to arise from the coelomic epithelium of the ovarian surface, it is now becoming clearer that the majority of serous carcinomas arise from epithelium ...

Last Updated: 2 Jun 2016

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Update on Intraperitoneal Chemotherapy for the Treatment of Epithelial Ovarian Cancer.
 

Author(s): Charlie Gourley, Joan L Walker, Helen J Mackay

Journal: Am Soc Clin Oncol Educ Book. 2016 ;35():143-51.

 

Surgical treatment and chemotherapy administration in women with epithelial ovarian cancer is more controversial today than at any point in the last 3 decades. The use of chemotherapy administered intraperitoneally has been particularly contentious. Three large randomized phase III ...

Last Updated: 2 Jun 2016

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Morphologic, Immunophenotypic, and Molecular Features of Epithelial Ovarian Cancer.
 

Author(s): Preetha Ramalingam

Journal: Oncology (Williston Park, N.Y.). 2016 Feb;30(2):166-76.

 

Epithelial ovarian cancer comprises a heterogeneous group of tumors. The four most common subtypes are serous, endometrioid, clear cell, and mucinous carcinoma. Less common are transitional cell tumors, including transitional cell carcinoma and malignant Brenner tumor. While in the ...

Last Updated: 19 Feb 2016

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Optimisation of Disease Management in Patients With Epithelial Ovarian Cancer in France
 

Status: Not yet recruiting

Condition Summary: Ovarian Epithelial Cancer

 

Last Updated: 5 Dec 2016

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p53 Gene in Treatment of Recurrent Ovarian Epithelial Cancer, Fallopian Tube Cancer, and Primary Peritoneal Cancer
 

Status: Not yet recruiting

Condition Summary: Ovarian Epithelial Cancer; Fallopian Tube Cancer; Primary Peritoneal Cancer

 

Last Updated: 30 Apr 2015

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Impact of Fas/FasL in Chemotherapy Response in Epithelial Ovarian Carcinoma
 

Status: Recruiting

Condition Summary: Ovarian Carcinoma

 

Last Updated: 16 Aug 2016

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