Orthostatic intolerance

Common Name(s)

Orthostatic intolerance

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Orthostatic intolerance" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Orthostatic intolerance" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Orthostatic intolerance" returned 52 free, full-text research articles on human participants. First 3 results:

Orthostatic intolerance without postural tachycardia: how much dysautonomia?
 

Author(s): Ajay K Parsaik, Wolfgang Singer, Thomas G Allison, David M Sletten, Michael J Joyner, Eduardo E Benarroch, Phillip A Low, Paola Sandroni

Journal: Clin. Auton. Res.. 2013 Aug;23(4):181-8.

 

Chronic symptoms of orthostatic intolerance occur in postural tachycardia syndrome (POTS) and patients with orthostatic intolerance (OI) without tachycardia. We recently reported that deconditioning is almost universal in both patient groups. In this study, we focussed on the question ...

Last Updated: 7 Aug 2013

Go To URL
Syncope and orthostatic intolerance increase risk of brain lesions in migraineurs and controls.
 

Author(s): Mark C Kruit, Roland D Thijs, Michel D Ferrari, Lenore J Launer, Mark A van Buchem, J Gert van Dijk

Journal: Neurology. 2013 May;80(21):1958-65.

 

We and others showed that migraineurs are at increased risk of subclinical and clinical ischemic brain lesions. Migraineurs also have a higher prevalence of frequent syncope and orthostatic intolerance, symptoms that are associated with transient reductions in cerebral blood flow. ...

Last Updated: 21 May 2013

Go To URL
[A family-based transmission disequilibrium test of polymorphisms of endothelial nitric oxide synthase gene in children with orthostatic intolerance].
 

Author(s): Zhen-Yu Xiong, Zi-Yan Han, Zhen-Hui Han, Xi Zhang, Xi-Qing Gao, Yong Gai, Jie Lian

Journal: Zhongguo Dang Dai Er Ke Za Zhi. 2012 Dec;14(12):960-3.

 

Recent studies have found that the variation of G894T on the region of T786C and 7th exon promoted by endothelial nitric oxide synthase (eNOS) gene is associated with cardiovascular disease. This research explored possible correlations between eNOS gene polymorphisms and orthostatic ...

Last Updated: 13 Dec 2012

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Orthostatic intolerance" returned 5 free, full-text review articles on human participants. First 3 results:

Common syndromes of orthostatic intolerance.
 

Author(s): Julian M Stewart

Journal: Pediatrics. 2013 May;131(5):968-80.

 

The autonomic nervous system, adequate blood volume, and intact skeletal and respiratory muscle pumps are essential components for rapid cardiovascular adjustments to upright posture (orthostasis). Patients lacking sufficient blood volume or having defective sympathetic adrenergic ...

Last Updated: 2 May 2013

Go To URL
Update on the theory and management of orthostatic intolerance and related syndromes in adolescents and children.
 

Author(s): Julian M Stewart

Journal: Expert Rev Cardiovasc Ther. 2012 Nov;10(11):1387-99.

 

Orthostasis means standing upright. One speaks of orthostatic intolerance (OI) when signs, such as hypotension, and symptoms, such as lightheadedness, occur when upright and are relieved by recumbence. The experience of transient mild OI is part of daily life. 'Initial orthostatic ...

Last Updated: 18 Dec 2012

Go To URL
Mechanisms of sympathetic regulation in orthostatic intolerance.
 

Author(s): Julian M Stewart

Journal: J. Appl. Physiol.. 2012 Nov;113(10):1659-68.

 

Sympathetic circulatory control is key to the rapid cardiovascular adjustments that occur within seconds of standing upright (orthostasis) and which are required for bipedal stance. Indeed, patients with ineffective sympathetic adrenergic vasoconstriction rapidly develop orthostatic ...

Last Updated: 16 Nov 2012

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Treatment of Orthostatic Intolerance in Patients With Parkinson's Disease Using Midodrine
 

Status: Recruiting

Condition Summary: Orthostatic Intolerance; Parkinson's Disease

 

Last Updated: 17 Feb 2015

Go to URL
Genetic Basis of Mitral Valve Prolapse
 

Status: Recruiting

Condition Summary: Mitral Valve Prolapse

 

Last Updated: 8 Apr 2015

Go to URL
Pathophysiology of Orthostatic Intolerance
 

Status: Recruiting

Condition Summary: Tachycardia; Postural Orthostatic Tachycardia Syndrome

 

Last Updated: 18 Dec 2014

Go to URL