Orthostatic intolerance

Common Name(s)

Orthostatic intolerance

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Orthostatic intolerance" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Orthostatic intolerance" returned 54 free, full-text research articles on human participants. First 3 results:

Does goal-directed fluid therapy affect postoperative orthostatic intolerance?: A randomized trial.
 

Author(s): Morten Bundgaard-Nielsen, Øivind Jans, Rasmus G Müller, André Korshin, Birgitte Ruhnau, Peter Bie, Niels H Secher, Henrik Kehlet

Journal: Anesthesiology. 2013 Oct;119(4):813-23.

 

Early mobilization is important for postoperative recovery but is limited by orthostatic intolerance (OI) with a prevalence of 50% 6 h after major surgery. The pathophysiology of postoperative OI is assumed to include hypovolemia besides dysregulation of vasomotor tone. Stroke volume-guided ...

Last Updated: 8 Nov 2013

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Orthostatic intolerance without postural tachycardia: how much dysautonomia?
 

Author(s): Ajay K Parsaik, Wolfgang Singer, Thomas G Allison, David M Sletten, Michael J Joyner, Eduardo E Benarroch, Phillip A Low, Paola Sandroni

Journal: Clin. Auton. Res.. 2013 Aug;23(4):181-8.

 

Chronic symptoms of orthostatic intolerance occur in postural tachycardia syndrome (POTS) and patients with orthostatic intolerance (OI) without tachycardia. We recently reported that deconditioning is almost universal in both patient groups. In this study, we focussed on the question ...

Last Updated: 7 Aug 2013

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Syncope and orthostatic intolerance increase risk of brain lesions in migraineurs and controls.
 

Author(s): Mark C Kruit, Roland D Thijs, Michel D Ferrari, Lenore J Launer, Mark A van Buchem, J Gert van Dijk

Journal: Neurology. 2013 May;80(21):1958-65.

 

We and others showed that migraineurs are at increased risk of subclinical and clinical ischemic brain lesions. Migraineurs also have a higher prevalence of frequent syncope and orthostatic intolerance, symptoms that are associated with transient reductions in cerebral blood flow. ...

Last Updated: 21 May 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Orthostatic intolerance" returned 5 free, full-text review articles on human participants. First 3 results:

Common syndromes of orthostatic intolerance.
 

Author(s): Julian M Stewart

Journal: Pediatrics. 2013 May;131(5):968-80.

 

The autonomic nervous system, adequate blood volume, and intact skeletal and respiratory muscle pumps are essential components for rapid cardiovascular adjustments to upright posture (orthostasis). Patients lacking sufficient blood volume or having defective sympathetic adrenergic ...

Last Updated: 2 May 2013

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Update on the theory and management of orthostatic intolerance and related syndromes in adolescents and children.
 

Author(s): Julian M Stewart

Journal: Expert Rev Cardiovasc Ther. 2012 Nov;10(11):1387-99.

 

Orthostasis means standing upright. One speaks of orthostatic intolerance (OI) when signs, such as hypotension, and symptoms, such as lightheadedness, occur when upright and are relieved by recumbence. The experience of transient mild OI is part of daily life. 'Initial orthostatic ...

Last Updated: 18 Dec 2012

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Mechanisms of sympathetic regulation in orthostatic intolerance.
 

Author(s): Julian M Stewart

Journal: J. Appl. Physiol.. 2012 Nov;113(10):1659-68.

 

Sympathetic circulatory control is key to the rapid cardiovascular adjustments that occur within seconds of standing upright (orthostasis) and which are required for bipedal stance. Indeed, patients with ineffective sympathetic adrenergic vasoconstriction rapidly develop orthostatic ...

Last Updated: 16 Nov 2012

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Treatment of Orthostatic Intolerance
 

Status: Recruiting

Condition Summary: Tachycardia; Chronic Orthostatic Intolerance

 

Last Updated: 7 Jan 2013

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Genetic Basis of Mitral Valve Prolapse
 

Status: Recruiting

Condition Summary: Mitral Valve Prolapse

 

Last Updated: 31 Oct 2012

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Pathophysiology of Orthostatic Intolerance
 

Status: Recruiting

Condition Summary: Tachycardia; Postural Orthostatic Tachycardia Syndrome

 

Last Updated: 7 Jan 2013

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