Oral cancer

Common Name(s)

Oral cancer

Oral cancer includes cancers of the mouth, lips, and oropharynx (the part of the throat at the back of the mouth).  Most cases are designated as squamous cell carcinomas because they begin in the flat cells (squamous cells) that cover the surfaces of the mouth, tongue, and lips. About 35,000 individuals in the United Stated are diagnosed with oral cancer each year. The use of alcohol and/or tobacco is associated with approximately 75 percent of oral cancers. Treatment for oral cancer may include surgery, radiation therapy, chemotherapy, or targeted therapy.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Oral cancer" for support, advocacy or research.

4th Angel Mentoring Program

Learning that you have cancer can be an overwhelming experience – one that leaves you frightened, vulnerable and alone. The 4th Angel Mentoring Program offers free, one-on-one, confidential outreach and support from someone who has successfully made the same journey you are about to begin – the journey towards recovery. This specially trained volunteer and cancer survivor – your 4th Angel – is someone who will talk and listen in a supportive setting. The 4th Angel Mentoring Program is telephone based, so you can be connect with an angel anywhere in the country. 4th Angel Mentoring Program is part of The Scott Hamilton CARES Initiative, a national non-profit organizat

Last Updated: 12 Dec 2012

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The Oral Cancer Foundation

Through increased public and professional awareness, prevention through lifestyle changes, early detection initiatives, education, improved treatment modalities, and sponsorship of research, the Oral Cancer Foundation's mission is to contribute to the reduction of suffering, permanent physical damage and disfigurement, and death caused by this disease.

Last Updated: 20 Feb 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Oral cancer" for support, advocacy or research.

4th Angel Mentoring Program

Learning that you have cancer can be an overwhelming experience – one that leaves you frightened, vulnerable and alone. The 4th Angel Mentoring Program offers free, one-on-one, confidential outreach and support from someone who has successfully made the same journey you are about to begin – the journey towards recovery. This specially trained volunteer and cancer survivor – your 4th Angel – is someone who will talk and listen in a supportive setting. The 4th Angel Mentoring Program is telephone based, so you can be connect with an angel anywhere in the country. 4th Angel Mentoring Program is part of The Scott Hamilton CARES Initiative, a national non-profit organizat

http://www.4thangel.org

Last Updated: 12 Dec 2012

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The Oral Cancer Foundation

Through increased public and professional awareness, prevention through lifestyle changes, early detection initiatives, education, improved treatment modalities, and sponsorship of research, the Oral Cancer Foundation's mission is to contribute to the reduction of suffering, permanent physical damage and disfigurement, and death caused by this disease.

http://oralcancer.org/

Last Updated: 20 Feb 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Oral cancer" returned 1337 free, full-text research articles on human participants. First 3 results:

Comparative effectiveness of instructional methods: oral and pharyngeal cancer examination.
 

Author(s): Nereyda P Clark, John G Marks, Pamela R Sandow, Christine E Seleski, Henrietta L Logan

Journal: J Dent Educ. 2014 Apr;78(4):622-9.

 

This study compared the effectiveness of different methods of instruction for the oral and pharyngeal cancer examination. A group of thirty sophomore students at the University of Florida College of Dentistry were randomly assigned to three training groups: video instruction, a faculty-led ...

Last Updated: 7 Apr 2014

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Double-blind, placebo-controlled, randomized phase II study of TJ-14 (hangeshashinto) for gastric cancer chemotherapy-induced oral mucositis.
 

Author(s): Toru Aoyama, Kazuhiro Nishikawa, Nobuhiro Takiguchi, Kazuaki Tanabe, Motohiro Imano, Ryoji Fukushima, Junichi Sakamoto, Mari S Oba, Satoshi Morita, Toru Kono, Akira Tsuburaya

Journal: Cancer Chemother. Pharmacol.. 2014 May;73(5):1047-54.

 

Hangeshashinto (TJ-14, a Kampo medicine), which reduces the level of prostaglandin E2 and affects the cyclooxygenase activity, alleviates chemotherapy-induced oral mucositis (COM). We conducted a randomized comparative trial to investigate whether TJ-14 prevents and controls COM in ...

Last Updated: 28 Apr 2014

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A combination of oral uracil-tegafur plus leucovorin (UFT + LV) is a safe regimen for adjuvant chemotherapy after hepatectomy in patients with colorectal cancer: safety report of the UFT/LV study.
 

Author(s): Akio Saiura, Junji Yamamoto, Kiyoshi Hasegawa, Masaru Oba, Tadatoshi Takayama, Shinichi Miyagawa, Masayoshi Ijichi, Masanori Teruya, Fuyo Yoshimi, Seiji Kawasaki, Hiroto Koyama, Masatoshi Makuuchi, Norihiro Kokudo

Journal: Drug Discov Ther. 2014 Feb;8(1):48-56.

 

The use of adjuvant systemic chemotherapy for resectable liver metastases from colorectal cancer (CRC) is controversial because no trial demonstrated its benefit. We conducted the phase III trial to evaluate UFT/leucovorin (LV) for colorectal liver metastases (CRLM). The primary endpoint ...

Last Updated: 20 Mar 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Oral cancer" returned 119 free, full-text review articles on human participants. First 3 results:

Oral contraceptive use for the primary prevention of ovarian cancer.
 

Author(s): Laura J Havrilesky, Jennifer M Gierisch, Patricia G Moorman, Remy R Coeytaux, Rachel Peragallo Urrutia, William J Lowery, Michaela Dinan, Amanda J McBroom, Liz Wing, Michael D Musty, Kathryn R Lallinger, Vic Hasselblad, Gillian D Sanders, Evan R Myers

Journal: Evid Rep Technol Assess (Full Rep). 2013 Jun;(212):1-514.

 

To estimate the overall balance of harms and benefits from the potential use of oral contraceptives (OCs) for the primary prevention of ovarian cancer

Last Updated: 15 Jan 2014

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Protection of dietary polyphenols against oral cancer.
 

Author(s): Yijian Ding, Hua Yao, Yanan Yao, Leonard Yenwong Fai, Zhuo Zhang

Journal:

 

Oral cancer represents a health burden worldwide with approximate 275,000 new cases diagnosed annually. Its poor prognosis is due to local tumor invasion and frequent lymph node metastasis. Better understanding and development of novel treatments and chemo-preventive approaches for ...

Last Updated: 17 Jun 2013

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Levels of scientific evidence of the quality of life in patients treated for oral cancer.
 

Author(s): Rocío Barrios, Javier Montero, Miguel-Angel González-Moles, Pilar Baca, Manuel Bravo

Journal:

 

Treatments used in cancer of the oral cavity have great impact on the physical, psychological and functional state of patients. There has been increasingly interest in evaluating the health-related quality of life using questionnaires among patients treated with oral cancer. Up to ...

Last Updated: 1 Jul 2013

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Study on the Carcinogenesis of Gα12 in Oral Cancer, and the Treatment of Oral Cancer Using Ga12 Inhibitor.
 

Status: Recruiting

Condition Summary: Carcinogenesis; Oral Cancer

 

Last Updated: 14 Apr 2014

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Last Updated: 8 Dec 2013

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Validation of DNA Methylation Biomarkers for Oral Cancer Detection
 

Status: Recruiting

Condition Summary: Oral Cancer

 

Last Updated: 14 Apr 2014

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