Oral cancer

Common Name(s)

Oral cancer

Oral cancer includes cancers of the mouth, lips, and oropharynx (the part of the throat at the back of the mouth).  Most cases are designated as squamous cell carcinomas because they begin in the flat cells (squamous cells) that cover the surfaces of the mouth, tongue, and lips. About 35,000 individuals in the United Stated are diagnosed with oral cancer each year. The use of alcohol and/or tobacco is associated with approximately 75 percent of oral cancers. Treatment for oral cancer may include surgery, radiation therapy, chemotherapy, or targeted therapy.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Oral cancer" for support, advocacy or research.

4th Angel Mentoring Program

Learning that you have cancer can be an overwhelming experience – one that leaves you frightened, vulnerable and alone. The 4th Angel Mentoring Program offers free, one-on-one, confidential outreach and support from someone who has successfully made the same journey you are about to begin – the journey towards recovery. This specially trained volunteer and cancer survivor – your 4th Angel – is someone who will talk and listen in a supportive setting. The 4th Angel Mentoring Program is telephone based, so you can be connect with an angel anywhere in the country. 4th Angel Mentoring Program is part of The Scott Hamilton CARES Initiative, a national non-profit organizat

Last Updated: 12 Dec 2012

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Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

Last Updated: 29 Jul 2015

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The Oral Cancer Foundation

Through increased public and professional awareness, prevention through lifestyle changes, early detection initiatives, education, improved treatment modalities, and sponsorship of research, the Oral Cancer Foundation's mission is to contribute to the reduction of suffering, permanent physical damage and disfigurement, and death caused by this disease.

Last Updated: 20 Feb 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Oral cancer" for support, advocacy or research.

4th Angel Mentoring Program

Learning that you have cancer can be an overwhelming experience – one that leaves you frightened, vulnerable and alone. The 4th Angel Mentoring Program offers free, one-on-one, confidential outreach and support from someone who has successfully made the same journey you are about to begin – the journey towards recovery. This specially trained volunteer and cancer survivor – your 4th Angel – is someone who will talk and listen in a supportive setting. The 4th Angel Mentoring Program is telephone based, so you can be connect with an angel anywhere in the country. 4th Angel Mentoring Program is part of The Scott Hamilton CARES Initiative, a national non-profit organizat

http://www.4thangel.org

Last Updated: 12 Dec 2012

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Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

http://www.CancerHopeNetwork.org

Last Updated: 29 Jul 2015

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The Oral Cancer Foundation

Through increased public and professional awareness, prevention through lifestyle changes, early detection initiatives, education, improved treatment modalities, and sponsorship of research, the Oral Cancer Foundation's mission is to contribute to the reduction of suffering, permanent physical damage and disfigurement, and death caused by this disease.

http://oralcancer.org/

Last Updated: 20 Feb 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Oral cancer" returned 1871 free, full-text research articles on human participants. First 3 results:

A Novel Peptide for Simultaneously Enhanced Treatment of Head and Neck Cancer and Mitigation of Oral Mucositis.
 

Author(s): Peili Chen, Maria Mancini, Stephen T Sonis, Juan Fernandez-Martinez, Jing Liu, Ezra E W Cohen, F Gary Toback

Journal:

 

We have characterized a novel 21 amino acid-peptide derived from Antrum Mucosal Protein (AMP)-18 that mediates growth promotion of cultured normal epithelial cells and mitigates radiation-induced oral mucositis in animal models, while suppressing in vitro function of cancer cells. ...

Last Updated: 7 Apr 2016

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Age Effects and Temporal Trends in HPV-Related and HPV-Unrelated Oral Cancer in the United States: A Multistage Carcinogenesis Modeling Analysis.
 

Author(s): Andrew F Brouwer, Marisa C Eisenberg, Rafael Meza

Journal:

 

Differences in prognosis in HPV-positive and HPV-negative oral (oropharyngeal and oral cavity) squamous cell carcinomas (OSCCs) and increasing incidence of HPV-related cancers have spurred interest in demographic and temporal trends in OSCC incidence. We leverage multistage clonal ...

Last Updated: 11 Mar 2016

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The Effect of Radiotherapy on Ultrasound-Guided Fine Needle Aspiration Biopsy and the Ultrasound Characteristics of Neck Lymph Nodes in Oral Cancer Patients after Primary Treatment.
 

Author(s): Wu-Chia Lo, Po-Wen Cheng, Chi-Te Wang, Pei-Wei Shueng, Chen-Hsi Hsieh, Yih-Leong Chang, Li-Jen Liao

Journal:

 

To investigate the effect of radiotherapy (RT) on ultrasound-guided fine needle aspiration (USgFNA) and sonographic characteristics in the assessment of cervical lymph nodes (LNs) in oral squamous cell carcinoma (OSCC) patients after primary treatment.

Last Updated: 9 Mar 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Oral cancer" returned 177 free, full-text review articles on human participants. First 3 results:

Molecular Mechanisms of Chemoresistance in Oral Cancer.
 

Author(s): Cheng Wang, Xi Qiang Liu, Jin Song Hou, Jian Ning Wang, Hong Zhang Huang

Journal: Chin J Dent Res. 2016 Mar;19(1):25-33.

 

Oral cancer is an aggressive disease with the propensity for local recurrence and distal metastasis in the head and neck region. Currently, cisplatin-based chemotherapy or concurrent radiochemotherapy is still the first choice to treat the advanced stage cancers, in particular, the ...

Last Updated: 16 Mar 2016

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Roles of Human Papillomaviruses and p16 in Oral Cancer.
 

Author(s): Thanun Sritippho, Pareena Chotjumlong, Anak Iamaroon

Journal: Asian Pac. J. Cancer Prev.. 2015 ;16(15):6193-200.

 

Head and neck cancer, including oral cancer, is the sixth most common cancer in humans worldwide. More than 90% of oral cancers are of squamous cell carcinoma type. Recent studies have shown a strong relationship between human papillomavirus (HPV) infection and head and neck cancer, ...

Last Updated: 5 Oct 2015

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Ethanol versus Phytochemicals in Wine: Oral Cancer Risk in a Light Drinking Perspective.
 

Author(s): Elena M Varoni, Giovanni Lodi, Marcello Iriti

Journal:

 

This narrative review aims to summarize the current controversy on the balance between ethanol and phytochemicals in wine, focusing on light drinking and oral cancer. Extensive literature search included PUBMED and EMBASE databases to identify in human studies and systematic reviews ...

Last Updated: 3 Aug 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Validation of DNA Methylation Biomarkers for Oral Cancer Detection
 

Status: Recruiting

Condition Summary: Oral Cancer; Recurrence

 

Last Updated: 5 Jan 2016

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Expression of VEGF-C and VEGF-CR in Oral Cancers and Premalignant Lesions
 

Status: Recruiting

Condition Summary: Oral Cancer

 

Last Updated: 12 Sep 2005

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Validation of DNA Methylation Biomarkers for Oral Cancer Detection
 

Status: Recruiting

Condition Summary: Oral Cancer

 

Last Updated: 14 Apr 2014

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