Oral cancer

Common Name(s)

Oral cancer

Oral cancer includes cancers of the mouth, lips, and oropharynx (the part of the throat at the back of the mouth).  Most cases are designated as squamous cell carcinomas because they begin in the flat cells (squamous cells) that cover the surfaces of the mouth, tongue, and lips. About 35,000 individuals in the United Stated are diagnosed with oral cancer each year. The use of alcohol and/or tobacco is associated with approximately 75 percent of oral cancers. Treatment for oral cancer may include surgery, radiation therapy, chemotherapy, or targeted therapy.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Oral cancer" for support, advocacy or research.

4th Angel Mentoring Program

Learning that you have cancer can be an overwhelming experience – one that leaves you frightened, vulnerable and alone. The 4th Angel Mentoring Program offers free, one-on-one, confidential outreach and support from someone who has successfully made the same journey you are about to begin – the journey towards recovery. This specially trained volunteer and cancer survivor – your 4th Angel – is someone who will talk and listen in a supportive setting. The 4th Angel Mentoring Program is telephone based, so you can be connect with an angel anywhere in the country. 4th Angel Mentoring Program is part of The Scott Hamilton CARES Initiative, a national non-profit organizat

Last Updated: 12 Dec 2012

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The Oral Cancer Foundation

Through increased public and professional awareness, prevention through lifestyle changes, early detection initiatives, education, improved treatment modalities, and sponsorship of research, the Oral Cancer Foundation's mission is to contribute to the reduction of suffering, permanent physical damage and disfigurement, and death caused by this disease.

Last Updated: 20 Feb 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Oral cancer" for support, advocacy or research.

4th Angel Mentoring Program

Learning that you have cancer can be an overwhelming experience – one that leaves you frightened, vulnerable and alone. The 4th Angel Mentoring Program offers free, one-on-one, confidential outreach and support from someone who has successfully made the same journey you are about to begin – the journey towards recovery. This specially trained volunteer and cancer survivor – your 4th Angel – is someone who will talk and listen in a supportive setting. The 4th Angel Mentoring Program is telephone based, so you can be connect with an angel anywhere in the country. 4th Angel Mentoring Program is part of The Scott Hamilton CARES Initiative, a national non-profit organizat

http://www.4thangel.org

Last Updated: 12 Dec 2012

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The Oral Cancer Foundation

Through increased public and professional awareness, prevention through lifestyle changes, early detection initiatives, education, improved treatment modalities, and sponsorship of research, the Oral Cancer Foundation's mission is to contribute to the reduction of suffering, permanent physical damage and disfigurement, and death caused by this disease.

http://oralcancer.org/

Last Updated: 20 Feb 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Oral cancer" returned 1372 free, full-text research articles on human participants. First 3 results:

Rapid adherence to collagen IV enriches for tumour initiating cells in oral cancer.
 

Author(s): Xiao Liang, Tarig Al-Hadi Osman, Dipak Sapkota, Evelyn Neppelberg, Stein Lybak, Per Gunnar Liavaag, Anne Christine Johannessen, Hege Karine Jacobsen, Per Øyvind Enger, Daniela Elena Costea, Jian Wang

Journal: Eur. J. Cancer. 2014 Dec;50(18):3262-70.

 

Although several approaches for identification and isolation of carcinoma cells with tumour initiating properties have been established, enrichment of a population of pure and viable tumour-initiating cells (TICs) is still problematic. This study investigated possibilities to isolate ...

Last Updated: 3 Dec 2014

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Oral cavity infection: an adverse effect after the treatment of oral cancer in aged individuals.
 

Author(s): Jie Pan, Jun Zhao, Ning Jiang

Journal: J Appl Oral Sci. ;22(4):261-7.

 

The immune compromised patients after treatment of oral cancer may have a chance of infection by drug-resistant opportunistic microbes. We investigated the occurrence of opportunistic microorganisms in aged individuals receiving follow-up examinations after treatment of oral cancer in China.

Last Updated: 21 Aug 2014

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Microbes and cancer geography: can we exploit recent lessons from the gut system to oral cancer context?
 

Author(s): Gustavo P Garlet, Carlos F Santos

Journal: J Appl Oral Sci. ;22(4):249-50.

 

Last Updated: 21 Aug 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Oral cancer" returned 136 free, full-text review articles on human participants. First 3 results:

Nanotechnology-based drug delivery systems for treatment of oral cancer: a review.
 

Author(s): Giovana Calixto, Jéssica Bernegossi, Bruno Fonseca-Santos, Marlus Chorilli

Journal:

 

Oral cancer (oral cavity and oropharynx) is a common and aggressive cancer that invades local tissue, can cause metastasis, and has a high mortality rate. Conventional treatment strategies, such as surgery and chemoradiotherapy, have improved over the past few decades; however, they ...

Last Updated: 21 Aug 2014

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Abnormal COX2 protein expression may be correlated with poor prognosis in oral cancer: a meta-analysis.
 

Author(s): Zhi-Ming Wang, Jie Liu, Hong-Bo Liu, Ming Ye, Yu-Fei Zhang, Dong-Sheng Yang

Journal: Biomed Res Int. 2014 ;2014():364207.

 

The prognostic significance of COX2 for survival of patients with oral cancer remains controversial. Thus, the meta-analysis was performed in order to identify COX2 expression impact on prognosis of oral cancer.

Last Updated: 16 Jul 2014

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An overview of the spindle assembly checkpoint status in oral cancer.
 

Author(s): José Henrique Teixeira, Patrícia Manuela Silva, Rita Margarida Reis, Inês Moranguinho Moura, Sandra Marques, Joana Fonseca, Luís Silva Monteiro, Hassan Bousbaa

Journal: Biomed Res Int. 2014 ;2014():145289.

 

Abnormal chromosome number, or aneuploidy, is a common feature of human solid tumors, including oral cancer. Deregulated spindle assembly checkpoint (SAC) is thought as one of the mechanisms that drive aneuploidy. In normal cells, SAC prevents anaphase onset until all chromosomes ...

Last Updated: 4 Jul 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Expression of VEGF-C and VEGF-CR in Oral Cancers and Premalignant Lesions
 

Status: Recruiting

Condition Summary: Oral Cancer

 

Last Updated: 12 Sep 2005

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Validation of DNA Methylation Biomarkers for Oral Cancer Detection
 

Status: Recruiting

Condition Summary: Oral Cancer

 

Last Updated: 14 Apr 2014

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Study on the Carcinogenesis of Gα12 in Oral Cancer, and the Treatment of Oral Cancer Using Ga12 Inhibitor.
 

Status: Recruiting

Condition Summary: Carcinogenesis; Oral Cancer

 

Last Updated: 14 Apr 2014

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