Optic pathway glioma

Common Name(s)

Optic pathway glioma

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Optic pathway glioma" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Optic pathway glioma" returned 14 free, full-text research articles on human participants. First 3 results:

Optic pathway glioma volume predicts retinal axon degeneration in neurofibromatosis type 1.
 

Author(s): Robert A Avery, Awais Mansoor, Rabia Idrees, Carmelina Trimboli-Heidler, Hiroshi Ishikawa, Roger J Packer, Marius George Linguraru

Journal: Neurology. 2016 Dec;87(23):2403-2407.

 

To determine whether tumor size is associated with retinal nerve fiber layer (RNFL) thickness, a measure of axonal degeneration and an established biomarker of visual impairment in children with optic pathway gliomas (OPGs) secondary to neurofibromatosis type 1 (NF1).

Last Updated: 31 Dec 1969

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High-Dose Intravenous Vitamin C Treatment of a Child with Neurofibromatosis Type 1 and Optic Pathway Glioma: A Case Report.
 

Author(s): Nina Mikirova, Ronald Hunnunghake, Ruth C Scimeca, Charles Chinshaw, Faryal Ali, Chris Brannon, Neil Riordan

Journal:

 

BACKGROUND In neurofibromatosis type 1 (NF1) disease, the loss of the tumor suppressor function of the neurofibromin gene leads to proliferation of neural tumors. In children, the most frequently identified tumor is the optic pathway glioma. CASE REPORT We describe the case of a 5-year-old ...

Last Updated: 31 Dec 1969

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Long-term visual outcome after chemotherapy for optic pathway glioma in children: Site and age are strongly predictive.
 

Author(s): Andrew J Dodgshun, James E Elder, Jordan R Hansford, Michael J Sullivan

Journal: Cancer. 2015 Dec;121(23):4190-6.

 

Optic pathway gliomas (OPGs) are commonly noted in pediatric oncology services. Radiotherapy is effective at controlling tumors, but has many undesirable late effects, especially in patients with neurofibromatosis. Chemotherapy is commonly used to preserve vision and delay or eliminate ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Optic pathway glioma" returned 1 free, full-text review articles on human participants. First 3 results:

A patient with optic pathway glioma, scoliosis, Chiari type I malformation and syringomyelia: is it Neurofibromatosis type 1?
 

Author(s): A Chakravarty, A Bhargava, S Nandy

Journal: Neurol India. 2002 Dec;50(4):520-1.

 

A 22 years old girl had features of optic pathway glioma, scoliosis, Chiari type 1 malformation and cervical syringomyelia. She had no cutaneous lesions. We considered this combination to be more than coincidental and argue in favour of considering the case as a variant form of Neurofibromatosis ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Phase II Pegylated Interferon
 

Status: Recruiting

Condition Summary: Juvenile Pilocytic Astrocytomas; Optic Pathway Gliomas

 

Last Updated: 4 Jun 2018

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Intermittent Dosing Of Selumetinib In Childhood NF1 Associated Tumours
 

Status: Not yet recruiting

Condition Summary: Neurofibromatosis Type 1; Plexiform Neurofibroma; Optic Nerve Glioma

 

Last Updated: 23 Feb 2018

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Hypotonia and Neurofibromatosis Type 1 (NF1) Glioma
 

Status: Recruiting

Condition Summary: Neurofibromatosis Type 1

 

Last Updated: 16 Mar 2018

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