Optic neuritis

Common Name(s)

Optic neuritis

Optic neuritis is inflammation of the optic nerve, the nerve that carries the visual signal from the eye to the brain.  The condition may cause sudden, reduced vision in the affected eye(s). While the cause of optic neuritis is unknown, it has been associated with autoimmune diseases, infections, multiple sclerosis, drug toxicity and deficiency of vitamin B-12. Vision often returns to normal within 2-3 weeks without treatment. In some cases, corticosteroids are given to speed recovery. If known, the underlying cause should be treated.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Optic neuritis" for support, advocacy or research.

The Transverse Myelitis Association

Our Mission is- -To support and advocate for individuals and their families diagnosed with rare neuro-immunologic disorders of the central nervous system -To promote awareness and to empower patients, families, clinicians and scientists through education programs and publications -To advance the scientific understanding of and therapy development for these rare disorders by supporting the training of clinicians-scientists dedicated to these rare diseases and by supporting basic and clinical research. OUR GOAL IS TO IMPROVE THE QUALITY OF LIFE OF INDIVIDUALS WITH THESE RARE NEURO-IMMUNOLOGIC DISORDERS

Last Updated: 29 Apr 2014

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Optic neuritis" for support, advocacy or research.

The Transverse Myelitis Association

Our Mission is- -To support and advocate for individuals and their families diagnosed with rare neuro-immunologic disorders of the central nervous system -To promote awareness and to empower patients, families, clinicians and scientists through education programs and publications -To advance the scientific understanding of and therapy development for these rare disorders by supporting the training of clinicians-scientists dedicated to these rare diseases and by supporting basic and clinical research. OUR GOAL IS TO IMPROVE THE QUALITY OF LIFE OF INDIVIDUALS WITH THESE RARE NEURO-IMMUNOLOGIC DISORDERS

http://www.myelitis.org/

Last Updated: 29 Apr 2014

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General Resources

Newsletters and publications

Quarterly newsletters and journals to update the community on current research and various community outreach events and opportunities.

Updated 5 Mar 2013

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Ask the Expert Podcast

Ask the Expert Podcast Series are held about once a month and the recordings are made available on the TMA website. The podcast is offered at no cost to TMA members and members share their questions in advance of the podcast for the experts.

Updated 29 Apr 2014

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Research and Educational Symposia

Recordings of all our national and international symposia are made available for our community to learn more about rare neuro-immune diseases

Updated 29 Apr 2014

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Physician Network

Physician network of specialists focused on rare neuro-immune diseases which is community sourced.

Updated 29 Apr 2014

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Blogs

The TMA Blog

Articles, news and reflections from our TMA members and medical professionals

Updated 5 Mar 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Optic neuritis" returned 308 free, full-text research articles on human participants. First 3 results:

MOG-IgG associated optic neuritis is not multiple sclerosis.
 

Author(s): Bruna Klein da Costa, Giordani Rodrigues Dos Passos, Jefferson Becker, Douglas Kazutoshi Sato

Journal: Arq Neuropsiquiatr. 2017 Oct;75(10):687-691.

 

Autoantibodies against myelin oligodendrocyte glycoprotein (MOG-IgG) have been reported in patients with inflammatory central nervous system disorders including isolated optic neuritis (ON). We compared our MOG-IgG ON patients with multiple sclerosis (MS) patients presenting with ON.

Last Updated: 31 Dec 1969

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Differences in pupillary light reflex between optic neuritis and ischemic optic neuropathy.
 

Author(s): Yung Ju Yoo, Jeong-Min Hwang, Hee Kyung Yang

Journal:

 

To determine the differences in pupillary light reflex (PLR) between the acute and chronic phases of optic neuritis (ON) and nonarteritic anterior ischemic optic neuropathy (NAION).

Last Updated: 31 Dec 1969

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Vascular hypoperfusion in acute optic neuritis is a potentially new neurovascular model for demyelinating diseases.
 

Author(s): Ta-Ching Chen, Chao-Yuan Yeh, Chao-Wen Lin, Chung-May Yang, Chang-Hao Yang, I-Hung Lin, Pao-Yang Chen, Jung-Yu Cheng, Fung-Rong Hu

Journal:

 

Optic neuritis is highly correlated with multiple sclerosis and is a major cause of acute visual loss and long-term neuronal degeneration. Primary cerebral hypoperfusion has been reported in brain demyelinating diseases. This study investigated whether peripapillary perfusion is changed ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Optic neuritis" returned 26 free, full-text review articles on human participants. First 3 results:

Targeting Oxidative Stress for Treatment of Glaucoma and Optic Neuritis.
 

Author(s): Atsuko Kimura, Kazuhiko Namekata, Xiaoli Guo, Takahiko Noro, Chikako Harada, Takayuki Harada

Journal: Oxid Med Cell Longev. 2017 ;2017():2817252.

 

Glaucoma is a neurodegenerative disease of the eye and it is one of the leading causes of blindness. Glaucoma is characterized by progressive degeneration of retinal ganglion cells (RGCs) and their axons, namely, the optic nerve, usually associated with elevated intraocular pressure ...

Last Updated: 31 Dec 1969

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Optic neuritis as an initial presentation of primary Sjögren syndrome: A case report and literature review.
 

Author(s): Jia-Yue Sun, Zheng Liu, Peng Zhao, Tao Liu

Journal: Medicine (Baltimore). 2016 Nov;95(44):e5194.

 

Primary Sjögren syndrome (pSS) is a progressive autoimmune disease that primarily affects exocrine glands. The clinical presentation of pSS may vary from an asymptomatic condition to severe skin symptom, resulting in a difficult and challenging diagnosis and treatment.

Last Updated: 31 Dec 1969

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Research Advances in Biomarkers for Demyelinating Optic Neuritis.
 

Author(s): Xiang Chen, Shi-hui Wei, Mao-nian Zhang

Journal: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2016 Feb;38(1):122-7.

 

Optic neuritis refers to all inflammatory diseases in the optic nerve. The most common type is demyelinating optic neuritis. Biomarkers can indicate its pathophysiological process and thus are useful in disease diagnosis and treatment. This article reviews the known biomarkers for ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

High-Dose Vitamin D Induction in Optic Neuritis
 

Status: Recruiting

Condition Summary: Optic Neuritis

 

Last Updated: 30 Nov 2017

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Optic Neuritis and Ganglion Cell Layer
 

Status: Recruiting

Condition Summary: Optic Neuritis

 

Last Updated: 3 Nov 2016

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