Optic neuritis

Common Name(s)

Optic neuritis

Optic neuritis is inflammation of the optic nerve, the nerve that carries the visual signal from the eye to the brain.  The condition may cause sudden, reduced vision in the affected eye(s). While the cause of optic neuritis is unknown, it has been associated with autoimmune diseases, infections, multiple sclerosis, drug toxicity and deficiency of vitamin B-12. Vision often returns to normal within 2-3 weeks without treatment. In some cases, corticosteroids are given to speed recovery. If known, the underlying cause should be treated.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Optic neuritis" for support, advocacy or research.

The Transverse Myelitis Association

Our Mission is- -To support and advocate for individuals and their families diagnosed with rare neuro-immunologic disorders of the central nervous system -To promote awareness and to empower patients, families, clinicians and scientists through education programs and publications -To advance the scientific understanding of and therapy development for these rare disorders by supporting the training of clinicians-scientists dedicated to these rare diseases and by supporting basic and clinical research. OUR GOAL IS TO IMPROVE THE QUALITY OF LIFE OF INDIVIDUALS WITH THESE RARE NEURO-IMMUNOLOGIC DISORDERS

Last Updated: 29 Apr 2014

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Optic neuritis" for support, advocacy or research.

The Transverse Myelitis Association

Our Mission is- -To support and advocate for individuals and their families diagnosed with rare neuro-immunologic disorders of the central nervous system -To promote awareness and to empower patients, families, clinicians and scientists through education programs and publications -To advance the scientific understanding of and therapy development for these rare disorders by supporting the training of clinicians-scientists dedicated to these rare diseases and by supporting basic and clinical research. OUR GOAL IS TO IMPROVE THE QUALITY OF LIFE OF INDIVIDUALS WITH THESE RARE NEURO-IMMUNOLOGIC DISORDERS

http://www.myelitis.org/

Last Updated: 29 Apr 2014

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General Resources

Newsletters and publications

Quarterly newsletters and journals to update the community on current research and various community outreach events and opportunities.

Updated 5 Mar 2013

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Ask the Expert Podcast

Ask the Expert Podcast Series are held about once a month and the recordings are made available on the TMA website. The podcast is offered at no cost to TMA members and members share their questions in advance of the podcast for the experts.

Updated 29 Apr 2014

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Research and Educational Symposia

Recordings of all our national and international symposia are made available for our community to learn more about rare neuro-immune diseases

Updated 29 Apr 2014

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Physician Network

Physician network of specialists focused on rare neuro-immune diseases which is community sourced.

Updated 29 Apr 2014

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Blogs

The TMA Blog

Articles, news and reflections from our TMA members and medical professionals

Updated 5 Mar 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Optic neuritis" returned 296 free, full-text research articles on human participants. First 3 results:

Change of Th17 Lymphocytes and Treg/Th17 in Typical and Atypical Optic Neuritis.
 

Author(s): Hengri Cong, Hanqiu Jiang, Jingting Peng, Shilei Cui, Lijuan Liu, Jiawei Wang, Xiaojun Zhang

Journal:

 

Typical and atypical optic neuritis (ON) are two clinical types of autoimmune inflammatory diseases of the optic nerve that causes acute vision loss, and are difficult to distinguish in their early stages. The disturbance in the balance of Th17 and Treg lymphocytes is thought to play ...

Last Updated: 20 Jan 2016

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Lesion Activity on Brain MRI in a Chinese Population with Unilateral Optic Neuritis.
 

Author(s): Chuntao Lai, Qinglin Chang, Guohong Tian, Jiawei Wang, Hongxia Yin, Wu Liu

Journal:

 

Longitudinal studies have shown that brain white matter lesions are strong predictors of the conversion of unilateral optic neuritis to multiple sclerosis (MS) in Caucasian populations. Consequently brain MRI criteria have been developed to improve the prediction of the development ...

Last Updated: 21 Oct 2015

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Atypical optic neuritis due to tuberculosis.
 

Author(s): Nataraja Pillai Venugopal

Journal: Indian J Ophthalmol. 2015 Jul;63(7):623.

 

Last Updated: 13 Oct 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Optic neuritis" returned 22 free, full-text review articles on human participants. First 3 results:

Research Advances in Biomarkers for Demyelinating Optic Neuritis.
 

Author(s): Xiang Chen, Shi-hui Wei, Mao-nian Zhang

Journal: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2016 Feb;38(1):122-7.

 

Optic neuritis refers to all inflammatory diseases in the optic nerve. The most common type is demyelinating optic neuritis. Biomarkers can indicate its pathophysiological process and thus are useful in disease diagnosis and treatment. This article reviews the known biomarkers for ...

Last Updated: 9 Mar 2016

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Corticosteroids for treating optic neuritis.
 

Author(s): Robin L Gal, Satyanarayana S Vedula, Roy Beck

Journal:

 

Optic neuritis is an inflammatory disease of the optic nerve. It usually presents with an abrupt loss of vision and recovery of vision is almost never complete. It occurs more commonly in women than in men. Closely linked in pathogenesis, optic neuritis may be the initial manifestation ...

Last Updated: 16 Nov 2015

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Re-evaluating the treatment of acute optic neuritis.
 

Author(s): Jeffrey L Bennett, Molly Nickerson, Fiona Costello, Robert C Sergott, Jonathan C Calkwood, Steven L Galetta, Laura J Balcer, Clyde E Markowitz, Timothy Vartanian, Mark Morrow, Mark L Moster, Andrew W Taylor, Thaddeus W W Pace, Teresa Frohman, Elliot M Frohman

Journal: J. Neurol. Neurosurg. Psychiatr.. 2015 Jul;86(7):799-808.

 

Clinical case reports and prospective trials have demonstrated a reproducible benefit of hypothalamic-pituitary-adrenal (HPA) axis modulation on the rate of recovery from acute inflammatory central nervous system (CNS) demyelination. As a result, corticosteroid preparations and adrenocorticotrophic ...

Last Updated: 13 Jun 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Optic Neuritis and Ganglion Cell Layer
 

Status: Recruiting

Condition Summary: Optic Neuritis

 

Last Updated: 10 Aug 2016

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Last Updated: 13 Apr 2016

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Lipoic Acid as a Treatment for Acute Optic Neuritis
 

Status: Recruiting

Condition Summary: Optic Neuritis

 

Last Updated: 2 Feb 2015

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