Optic neuritis

Common Name(s)

Optic neuritis

Optic neuritis is inflammation of the optic nerve, the nerve that carries the visual signal from the eye to the brain.  The condition may cause sudden, reduced vision in the affected eye(s). While the cause of optic neuritis is unknown, it has been associated with autoimmune diseases, infections, multiple sclerosis, drug toxicity and deficiency of vitamin B-12. Vision often returns to normal within 2-3 weeks without treatment. In some cases, corticosteroids are given to speed recovery. If known, the underlying cause should be treated.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Optic neuritis" for support, advocacy or research.

The Transverse Myelitis Association

Our Mission is- -To support and advocate for individuals and their families diagnosed with rare neuro-immunologic disorders of the central nervous system -To promote awareness and to empower patients, families, clinicians and scientists through education programs and publications -To advance the scientific understanding of and therapy development for these rare disorders by supporting the training of clinicians-scientists dedicated to these rare diseases and by supporting basic and clinical research. OUR GOAL IS TO IMPROVE THE QUALITY OF LIFE OF INDIVIDUALS WITH THESE RARE NEURO-IMMUNOLOGIC DISORDERS

Last Updated: 29 Apr 2014

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Optic neuritis" for support, advocacy or research.

The Transverse Myelitis Association

Our Mission is- -To support and advocate for individuals and their families diagnosed with rare neuro-immunologic disorders of the central nervous system -To promote awareness and to empower patients, families, clinicians and scientists through education programs and publications -To advance the scientific understanding of and therapy development for these rare disorders by supporting the training of clinicians-scientists dedicated to these rare diseases and by supporting basic and clinical research. OUR GOAL IS TO IMPROVE THE QUALITY OF LIFE OF INDIVIDUALS WITH THESE RARE NEURO-IMMUNOLOGIC DISORDERS

http://www.myelitis.org/

Last Updated: 29 Apr 2014

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General Resources

Newsletters and publications

Quarterly newsletters and journals to update the community on current research and various community outreach events and opportunities.

Updated 5 Mar 2013

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Ask the Expert Podcast

Ask the Expert Podcast Series are held about once a month and the recordings are made available on the TMA website. The podcast is offered at no cost to TMA members and members share their questions in advance of the podcast for the experts.

Updated 29 Apr 2014

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Research and Educational Symposia

Recordings of all our national and international symposia are made available for our community to learn more about rare neuro-immune diseases

Updated 29 Apr 2014

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Physician Network

Physician network of specialists focused on rare neuro-immune diseases which is community sourced.

Updated 29 Apr 2014

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Blogs

The TMA Blog

Articles, news and reflections from our TMA members and medical professionals

Updated 5 Mar 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Optic neuritis" returned 287 free, full-text research articles on human participants. First 3 results:

Initial Pattern of Optic Nerve Enhancement in Korean Patients with Unilateral Optic Neuritis.
 

Author(s): Dae Yong Son, Kyung-Ah Park, Su Sie Seok, Ju-Yeun Lee, Sei Yeul Oh

Journal: Korean J Ophthalmol. 2017 Feb;31(1):71-79.

 

The purpose of this study was to demonstrate whether the pattern of optic nerve enhancement in magnetic resonance imaging (MRI) can help to differentiate between idiopathic optic neuritis (ON), neuromyelitis optica (NMO), and multiple sclerosis (MS) in unilateral ON.

Last Updated: 28 Feb 2017

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Disease Activity and Conversion into Multiple Sclerosis after Optic Neuritis Is Treated with Erythropoietin.
 

Author(s): Kurt-Wolfram Sühs, Panagiotis Papanagiotou, Katharina Hein, Refik Pul, Kerstin Scholz, Christoph Heesen, Ricarda Diem

Journal:

 

Changes in cerebral lesion load by magnetic resonance imaging (MRI) in patients from a double-blind, placebo-controlled, phase II study on erythropoietin in clinically isolated optic neuritis (ClinicalTrials.gov, NCT00355095) were analyzed. Therefore, patients with acute optic neuritis ...

Last Updated: 5 Oct 2016

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Analysis of Fundus Photography and Fluorescein Angiography in Nonarteritic Anterior Ischemic Optic Neuropathy and Optic Neuritis.
 

Author(s): Min Kyung Kim, Ungsoo Samuel Kim

Journal: Korean J Ophthalmol. 2016 Aug;30(4):289-94.

 

We evaluated fundus and fluorescein angiography (FAG) findings and characteristics that can help distinguish nonarteritic anterior ischemic optic neuropathy (NAION) from optic neuritis (ON).

Last Updated: 1 Aug 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Optic neuritis" returned 26 free, full-text review articles on human participants. First 3 results:

Targeting Oxidative Stress for Treatment of Glaucoma and Optic Neuritis.
 

Author(s): Atsuko Kimura, Kazuhiko Namekata, Xiaoli Guo, Takahiko Noro, Chikako Harada, Takayuki Harada

Journal: Oxid Med Cell Longev. 2017 ;2017():2817252.

 

Glaucoma is a neurodegenerative disease of the eye and it is one of the leading causes of blindness. Glaucoma is characterized by progressive degeneration of retinal ganglion cells (RGCs) and their axons, namely, the optic nerve, usually associated with elevated intraocular pressure ...

Last Updated: 8 Mar 2017

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Optic neuritis as an initial presentation of primary Sjögren syndrome: A case report and literature review.
 

Author(s): Jia-Yue Sun, Zheng Liu, Peng Zhao, Tao Liu

Journal: Medicine (Baltimore). 2016 Nov;95(44):e5194.

 

Primary Sjögren syndrome (pSS) is a progressive autoimmune disease that primarily affects exocrine glands. The clinical presentation of pSS may vary from an asymptomatic condition to severe skin symptom, resulting in a difficult and challenging diagnosis and treatment.

Last Updated: 18 Nov 2016

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Research Advances in Biomarkers for Demyelinating Optic Neuritis.
 

Author(s): Xiang Chen, Shi-hui Wei, Mao-nian Zhang

Journal: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2016 Feb;38(1):122-7.

 

Optic neuritis refers to all inflammatory diseases in the optic nerve. The most common type is demyelinating optic neuritis. Biomarkers can indicate its pathophysiological process and thus are useful in disease diagnosis and treatment. This article reviews the known biomarkers for ...

Last Updated: 9 Mar 2016

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Defining the Functional and Neuro-Protective Potential of ACTHAR in Acute Optic Neuritis
 

Status: Recruiting

Condition Summary: Optic Neuritis

 

Last Updated: 20 Sep 2016

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Last Updated: 24 Oct 2016

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Optic Neuritis and Ganglion Cell Layer
 

Status: Recruiting

Condition Summary: Optic Neuritis

 

Last Updated: 3 Nov 2016

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