Aortic Valve Stenosis

Common Name(s)

Aortic Valve Stenosis

Aortic valve stenosis, or aortic stenosis, is a relatively common heart condition. Generally, blood is pumped by the heart to the rest of the body, exiting the heart through the aortic valve. Aortic stenosis is characterized by a narrowing of this valve. This narrowed valve can hinder blood flow from the heart, also causing the heart to work harder. Over time, this may weaken the heart muscle and cause fatigue and dizziness. Other symptoms include: chest pain, coughing (sometimes bloody), and breathing problems. Symptoms experienced by infants include: failure to gain weight, difficulty feeding, and serious breathing problems. This condition can be present from birth, but most often develops later in life due to the buildup of calcium in the valve. Aortic stenosis can affect both men and women, but is more common in men. Treatment includes medication to control blood pressure and possibly surgery to replace the valve.

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Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Aortic Valve Stenosis" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Aortic Valve Stenosis" returned 537 free, full-text research articles on human participants. First 3 results:

Transcatheter Aortic Valve Implantation for Treatment of Aortic Valve Stenosis: A Health Technology Assessment.
 

Author(s):

Journal:

 

Surgical aortic valve replacement (SAVR) is the gold standard for treating aortic valve stenosis. It is a major operation that requires sternotomy and the use of a heart-lung bypass machine, but in appropriately selected patients with symptomatic, severe aortic valve stenosis, the ...

Last Updated: 19 Dec 2016

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Mast Cells Might Have a Protective Role against the Development of Calcification and Hyalinisation in Severe Aortic Valve Stenosis.
 

Author(s): A Milutinovic, D Petrovič, M Zorc, O Vraspir Porenta, M Arko, A Pleskovič, A Alibegovic, R Zorc-Pleskovic

Journal: Folia Biol. (Praha). 2016 ;62(4):160-6.

 

Aortic valve stenosis is characterized by inflammation and extracellular matrix remodelling. The aim of this study was to analyse the impact of mast cells on the occurrence of histopathological changes of aortic valves in patients with severe grade, non-rheumatic degenerative aortic ...

Last Updated: 20 Sep 2016

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Quantification of Aortic Valve Calcifications Detected During Lung Cancer-Screening CT Helps Stratify Subjects Necessitating Echocardiography for Aortic Stenosis Diagnosis.
 

Author(s): Hee Young Lee, Sung Mok Kim, Kyung Soo Lee, Seung Woo Park, Myung Jin Chung, Hyoun Cho, Jung Im Jung, Hye Won Jang, Sin-Ho Jung, Juna Goo

Journal: Medicine (Baltimore). 2016 May;95(19):e3710.

 

No study has been published on aortic valve calcification (AVC) extent at lung cancer screening low-dose CT (LDCT) and its relationship with aortic stenosis (AS). The purpose of this study was to estimate the cutoff value of AVC on LDCT for detecting AS in asymptomatic Asian subjects. ...

Last Updated: 14 May 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Aortic Valve Stenosis" returned 35 free, full-text review articles on human participants. First 3 results:

Multimodality Imaging Strategies for the Assessment of Aortic Stenosis: Viewpoint of the Heart Valve Clinic International Database (HAVEC) Group.
 

Author(s): Raluca Dulgheru, Philippe Pibarot, Partho P Sengupta, Luc A Piérard, Raphael Rosenhek, Julien Magne, Erwan Donal, Anne Bernard, Khalil Fattouch, Bernard Cosyns, Mani Vannan, Linda Gillam, Patrizio Lancellotti

Journal: Circ Cardiovasc Imaging. 2016 Feb;9(2):e004352.

 

Aortic stenosis is the most frequent valvular heart disease. In aortic stenosis, therapeutic decision essentially depends on symptomatic status, stenosis severity, and status of left ventricular systolic function. Surgical aortic valve replacement or transcatheter aortic valve implantation ...

Last Updated: 11 Feb 2016

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The clinical challenge of concomitant aortic and mitral valve stenosis.
 

Author(s): Philippe Unger, Patrizzio Lancellotti, Didier de Cannière

Journal: Acta Cardiol. 2016 Feb;71(1):3-6.

 

The coexistence of mitral and aortic stenosis is not exceptional. Whereas rheumatic fever is currently plummeting in the Western countries, the incidence of degenerative disease is inversely increasing. The haemodynamic interactions which may interfere both with the usual echocardiographic ...

Last Updated: 8 Feb 2016

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Beyond adding years to life: health-related quality-of-life and functional outcomes in patients with severe aortic valve stenosis at high surgical risk undergoing transcatheter aortic valve replacement.
 

Author(s): Marcus-Andre Deutsch, Sabine Bleiziffer, Yacine Elhmidi, Nicolo Piazza, Bernhard Voss, Ruediger Lange, Markus Krane

Journal: Curr Cardiol Rev. 2013 Nov;9(4):281-94.

 

Aortic valve stenosis (AVS) is the most frequent acquired valvular heart disease in western industrialized countries and its prevalence considerably increases with age. Once becoming symptomatic severe AVS has a very poor prognosis. Progressive and rapid symptom deterioration leads ...

Last Updated: 21 Feb 2014

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Genetic of Aortic Valve Stenosis - Clinical and Therapeutic Implications
 

Status: Recruiting

Condition Summary: Aortic Valve Stenosis

 

Last Updated: 27 Feb 2017

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Sizing-sTrategy of Bicuspid AoRtic Valve Stenosis With Transcatheter Self-expandable Valve
 

Status: Not yet recruiting

Condition Summary: Aortic Valve Stenosis

 

Last Updated: 3 Sep 2015

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PCSK9 Inhibitors in the Progression of Aortic Stenosis
 

Status: Not yet recruiting

Condition Summary: Aortic Valve Stenosis

 

Last Updated: 8 Feb 2017

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