Aortic Valve Stenosis

Common Name(s)

Aortic Valve Stenosis

Aortic valve stenosis, or aortic stenosis, is a relatively common heart condition. Generally, blood is pumped by the heart to the rest of the body, exiting the heart through the aortic valve. Aortic stenosis is characterized by a narrowing of this valve. This narrowed valve can hinder blood flow from the heart, also causing the heart to work harder. Over time, this may weaken the heart muscle and cause fatigue and dizziness. Other symptoms include: chest pain, coughing (sometimes bloody), and breathing problems. Symptoms experienced by infants include: failure to gain weight, difficulty feeding, and serious breathing problems. This condition can be present from birth, but most often develops later in life due to the buildup of calcium in the valve. Aortic stenosis can affect both men and women, but is more common in men. Treatment includes medication to control blood pressure and possibly surgery to replace the valve.

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Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Aortic Valve Stenosis" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Aortic Valve Stenosis" returned 538 free, full-text research articles on human participants. First 3 results:

Apicoaortic Valve Conduit for a Patient with Aortic Valve Stenosis and Patent Coronary Bypass Grafts Using Cardiopulmonary Bypass.
 

Author(s): Anthony G Shackelford, Margaret A Relle, Sarah A Lombardi

Journal: J Extra Corpor Technol. 2015 Dec;47(4):233-6.

 

In adults over 65 years of age, aortic valve stenosis has been found to be present in 2-9% within this group. Furthermore, aortic valve replacements in patients whom have had a previous coronary artery bypass grafting surgery have a mortality rate as high as 18%. A non-conventional ...

Last Updated: 2 Feb 2016

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Aberrant Glycosylation of Lumican in Aortic Valve Stenosis Revealed by Proteomic Analysis.
 

Author(s): Hirotoshi Suzuki, Masahide Chikada, Michiyo K Yokoyama, Manae S Kurokawa, Takashi Ando, Hiroshi Furukawa, Mitsumi Arito, Takeshi Miyairi, Tomohiro Kato

Journal: Int Heart J. 2016 ;57(1):104-11.

 

To identify proteins related to the pathophysiology of aortic valve stenosis (AS), we investigated the protein profiles of AS aortic valves. Specifically, proteins were extracted from a thickened and calcified area (AS-C) and an apparently non-thickened and non-calcified area (AS-N) ...

Last Updated: 19 Jan 2016

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Relation of Left Ventricular Mass to Prognosis in Initially Asymptomatic Mild to Moderate Aortic Valve Stenosis.
 

Author(s): Eva Gerdts, Anne B Rossebø, Terje R Pedersen, Giovanni Cioffi, Mai Tone Lønnebakken, Dana Cramariuc, Barbara P Rogge, Richard B Devereux

Journal: Circ Cardiovasc Imaging. 2015 Nov;8(11):e003644; discussion e003644.

 

The prognostic importance of left ventricular (LV) mass in nonsevere asymptomatic aortic stenosis has not been documented in a large prospective study.

Last Updated: 22 Oct 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Aortic Valve Stenosis" returned 35 free, full-text review articles on human participants. First 3 results:

The clinical challenge of concomitant aortic and mitral valve stenosis.
 

Author(s): Philippe Unger, Patrizzio Lancellotti, Didier de Cannière

Journal: Acta Cardiol. 2016 Feb;71(1):3-6.

 

The coexistence of mitral and aortic stenosis is not exceptional. Whereas rheumatic fever is currently plummeting in the Western countries, the incidence of degenerative disease is inversely increasing. The haemodynamic interactions which may interfere both with the usual echocardiographic ...

Last Updated: 8 Feb 2016

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Balloon aortic valvuloplasty as a bridge to aortic valve surgery for severe aortic stenosis.
 

Author(s): Nnamdi Nwaejike, Keith Mills, Rod Stables, Mark Field

Journal: Interact Cardiovasc Thorac Surg. 2015 Mar;20(3):429-35.

 

A best evidence topic in cardiac surgery was written according to a structured protocol. The question addressed was, in patients with severe aortic stenosis, can balloon valvuloplasty be used as a bridge to aortic valve replacement? Altogether 463 papers were found using the reported ...

Last Updated: 14 Feb 2015

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Beyond adding years to life: health-related quality-of-life and functional outcomes in patients with severe aortic valve stenosis at high surgical risk undergoing transcatheter aortic valve replacement.
 

Author(s): Marcus-Andre Deutsch, Sabine Bleiziffer, Yacine Elhmidi, Nicolo Piazza, Bernhard Voss, Ruediger Lange, Markus Krane

Journal: Curr Cardiol Rev. 2013 Nov;9(4):281-94.

 

Aortic valve stenosis (AVS) is the most frequent acquired valvular heart disease in western industrialized countries and its prevalence considerably increases with age. Once becoming symptomatic severe AVS has a very poor prognosis. Progressive and rapid symptom deterioration leads ...

Last Updated: 21 Feb 2014

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Genetic of Aortic Valve Stenosis - Clinical and Therapeutic Implications
 

Status: Recruiting

Condition Summary: Aortic Valve Stenosis

 

Last Updated: 24 Feb 2016

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Preoperative Assessment of Aortic Valve Stenosis and Coronary Artery Disease
 

Status: Recruiting

Condition Summary: Aortic Valve Stenosis; Coronary Disease

 

Last Updated: 16 Apr 2013

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Left Atrial Volume Index in Asymptomatic Aortic Stenosis
 

Status: Recruiting

Condition Summary: Aortic Valve Stenosis; Heart Failure

 

Last Updated: 20 Mar 2015

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