Aortic Valve Stenosis

Common Name(s)

Aortic Valve Stenosis

Aortic valve stenosis, or aortic stenosis, is a relatively common heart condition. Generally, blood is pumped by the heart to the rest of the body, exiting the heart through the aortic valve. Aortic stenosis is characterized by a narrowing of this valve. This narrowed valve can hinder blood flow from the heart, also causing the heart to work harder. Over time, this may weaken the heart muscle and cause fatigue and dizziness. Other symptoms include: chest pain, coughing (sometimes bloody), and breathing problems. Symptoms experienced by infants include: failure to gain weight, difficulty feeding, and serious breathing problems. This condition can be present from birth, but most often develops later in life due to the buildup of calcium in the valve. Aortic stenosis can affect both men and women, but is more common in men. Treatment includes medication to control blood pressure and possibly surgery to replace the valve.

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Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Aortic Valve Stenosis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Aortic Valve Stenosis" returned 465 free, full-text research articles on human participants. First 3 results:

Relation of Left Ventricular Mass to Prognosis in Initially Asymptomatic Mild to Moderate Aortic Valve Stenosis.
 

Author(s): Eva Gerdts, Anne B Rossebø, Terje R Pedersen, Giovanni Cioffi, Mai Tone Lønnebakken, Dana Cramariuc, Barbara P Rogge, Richard B Devereux

Journal: Circ Cardiovasc Imaging. 2015 Nov;8(11):e003644; discussion e003644.

 

The prognostic importance of left ventricular (LV) mass in nonsevere asymptomatic aortic stenosis has not been documented in a large prospective study.

Last Updated: 22 Oct 2015

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Serum Dickkopf-1 signaling and calcium deposition in aortic valve are significantly related to the presence of concomitant coronary atherosclerosis in patients with symptomatic calcified aortic stenosis.
 

Author(s): Zuzana Motovska, Teodora Vichova, Magdalena Doktorova, Marek Labos, Marek Maly, Petr Widimsky

Journal:

 

The study aimed to assess serum RANKL:OPG ratio, Dkk-1 and deposition of calcium in aortic valve in relation to the presence of concomitant coronary atherosclerosis in patients with symptomatic calcified aortic stenosis (CAS).

Last Updated: 19 Apr 2015

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Iatrogenic left anterior descending artery stenosis early after aortic valve replacement presenting with T-wave-pseudonormalization - a case report.
 

Author(s): Stefan Schwarz, Hermann Blessberger, Jürgen Kammler, Christoph Gross, Clemens Steinwender

Journal:

 

Both iatrogenic coronary artery stenosis early after aortic valve replacement and pseudonormalization of inverted T-waves in acute ischemia are rare but well-recognized findings which coincide in this case.

Last Updated: 18 Apr 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Aortic Valve Stenosis" returned 32 free, full-text review articles on human participants. First 3 results:

Balloon aortic valvuloplasty as a bridge to aortic valve surgery for severe aortic stenosis.
 

Author(s): Nnamdi Nwaejike, Keith Mills, Rod Stables, Mark Field

Journal: Interact Cardiovasc Thorac Surg. 2015 Mar;20(3):429-35.

 

A best evidence topic in cardiac surgery was written according to a structured protocol. The question addressed was, in patients with severe aortic stenosis, can balloon valvuloplasty be used as a bridge to aortic valve replacement? Altogether 463 papers were found using the reported ...

Last Updated: 14 Feb 2015

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Beyond adding years to life: health-related quality-of-life and functional outcomes in patients with severe aortic valve stenosis at high surgical risk undergoing transcatheter aortic valve replacement.
 

Author(s): Marcus-Andre Deutsch, Sabine Bleiziffer, Yacine Elhmidi, Nicolo Piazza, Bernhard Voss, Ruediger Lange, Markus Krane

Journal: Curr Cardiol Rev. 2013 Nov;9(4):281-94.

 

Aortic valve stenosis (AVS) is the most frequent acquired valvular heart disease in western industrialized countries and its prevalence considerably increases with age. Once becoming symptomatic severe AVS has a very poor prognosis. Progressive and rapid symptom deterioration leads ...

Last Updated: 21 Feb 2014

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Cost-effectiveness of transcatheter aortic valve implantation (TAVI) for aortic stenosis in patients who are high risk or contraindicated for surgery: a model-based economic evaluation.
 

Author(s): R Orlando, M Pennant, S Rooney, S Khogali, S Bayliss, A Hassan, D Moore, P Barton

Journal: Health Technol Assess. 2013 Aug;17(33):1-86.

 

Calcific aortic stenosis (AS) is a common valvular heart disease. Patients with severe symptomatic AS typically survive less than 3 years. In such patients, intervention with surgical aortic valve replacement (SAVR) may increase survival. However, in some patients SAVR is associated ...

Last Updated: 16 Aug 2013

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Genetic of Aortic Valve Stenosis - Clinical and Therapeutic Implications
 

Status: Recruiting

Condition Summary: Aortic Valve Stenosis

 

Last Updated: 10 Apr 2015

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Preoperative Assessment of Aortic Valve Stenosis and Coronary Artery Disease
 

Status: Recruiting

Condition Summary: Aortic Valve Stenosis; Coronary Disease

 

Last Updated: 16 Apr 2013

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Left Atrial Volume Index in Asymptomatic Aortic Stenosis
 

Status: Recruiting

Condition Summary: Aortic Valve Stenosis; Heart Failure

 

Last Updated: 20 Mar 2015

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