Onchocerciasis

Common Name(s)

Onchocerciasis

Onchocerciasis, also known as river blindness, is a parasitic disease affecting the eyes and skin caused by the parasitic worm Onchocerca volvulus. Onchocerciasis is transmitted to humans through bites of infected blackflies. These blackflies are common in fast-flowing rivers and streams, typically in remote villages nearby fertile land used for agriculture. Symptoms of Onchocerciasis include severe itching, skin lesions, the development of nodules under the skin, and eye lesions that can lead to visual impairment and permanent blindness. This disease occurs primarily in tropical areas, with almost all of the infected people living in sub-Saharan Africa. Cases of this disease have also appeared in Yemen and Latin America. There is currently no vaccine or medication available to prevent infection.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Onchocerciasis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Onchocerciasis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Onchocerciasis" returned 334 free, full-text research articles on human participants. First 3 results:

Impact of Six Years Community Directed Treatment with Ivermectin in the Control of Onchocerciasis, Western Ethiopia.
 

Author(s): Abdi Samuel, Tariku Belay, Delenasaw Yehalaw, Mohammed Taha, Endalew Zemene, Ahmed Zeynudin

Journal:

 

The African Program for Onchocerciais Control (APOC) with a main strategy of community directed treatment with ivermectin (CDTI) was established with the aim of eliminating Onchocerciasis as a disease of public health and socio-economic importance. The study area was a hyper endemic ...

Last Updated: 5 Mar 2016

Go To URL
Presence of Wuchereria bancrofti microfilaremia despite 7 years of annual ivermectin monotherapy mass drug administration for onchocerciasis control: a study in north-west Ethiopia.
 

Author(s): Tekola Endeshaw, Aseged Taye, Zerihun Tadesse, Moses N Katabarwa, Oumer Shafi, Tewodros Seid, Frank O Richards

Journal: Pathog Glob Health. 2015 ;109(7):344-51.

 

There is considerable interest in determining whether mass drug administration (MDA) with ivermectin for onchocerciasis control will eliminate coendemic lymphatic filariasis (LF). The objective of this study was to determine the prevalence of LF microfilaremia in onchocerciasis endemic ...

Last Updated: 16 Feb 2016

Go To URL
Relationship between oral declaration on adherence to ivermectin treatment and parasitological indicators of onchocerciasis in an area of persistent transmission despite a decade of mass drug administration in Cameroon.
 

Author(s): Samuel Wanji, Jonas A Kengne-Ouafo, Mathias E Esum, Patrick W N Chounna, Bridget F Adzemye, Joan E E Eyong, Isaac Jato, Fabrice R Datchoua-Poutcheu, Raphael A Abong, Peter Enyong, David W Taylor

Journal:

 

Onchocerciasis control for years has been based on mass drug administration (MDA) with ivermectin (IVM). Adherence to IVM repeated treatment has recently been shown to be a confounding factor for onchocerciasis elimination precisely in rain forest areas where transmission continues ...

Last Updated: 30 Dec 2015

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Onchocerciasis" returned 19 free, full-text review articles on human participants. First 3 results:

Contribution and performance of female Community-Directed Distributors in the treatment of onchocerciasis with Ivermectin in Sub-Saharan Africa: a systematic review.
 

Author(s): Marius Zambou Vouking, Violette Claire Tamo, Carine Nouboudem Tadenfok

Journal:

 

The African Program for Onchocerciasis Control (APOC) was launched in 1995 with the main goal being to boost the fight against onchocerciasis in Africa. In 2011, over 80 million people benefited from this intervention thanks to the contribution of 268.718 Community-Directed Distributors ...

Last Updated: 2 Oct 2015

Go To URL
The Contributions of Onchocerciasis Control and Elimination Programs toward the Achievement of the Millennium Development Goals.
 

Author(s): Caitlin Dunn, Kelly Callahan, Moses Katabarwa, Frank Richards, Donald Hopkins, P Craig Withers, Lucas E Buyon, Deborah McFarland

Journal:

 

In 2000, 189 member states of the United Nations (UN) developed a plan for peace and development, which resulted in eight actionable goals known as the Millennium Development Goals (MDGs). Since their inception, the MDGs have been considered the international standard for measuring ...

Last Updated: 22 May 2015

Go To URL
African programme for onchocerciasis control 1995-2015: updated health impact estimates based on new disability weights.
 

Author(s): Luc E Coffeng, Wilma A Stolk, Honorat G M Zouré, J Lennert Veerman, Koffi B Agblewonu, Michele E Murdoch, Mounkaila Noma, Grace Fobi, Jan Hendrik Richardus, Donald A P Bundy, Dik Habbema, Sake J de Vlas, Uche V Amazigo

Journal:

 

Last Updated: 6 Jun 2014

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Efficacy of Ivermectin and Albendazole Against Onchocerciasis in the Volta Region, Ghana
 

Status: Not yet recruiting

Condition Summary: Onchocerciasis

 

Last Updated: 28 Feb 2014

Go to URL
Mass Drug Administration for Lymphatic Filariasis and Onchocerciasis for Liberia
 

Status: Recruiting

Condition Summary: Lymphatic Filariasis; Onchocerciasis; Soil Transmitted Helminth (STH) Infections

 

Last Updated: 21 Nov 2016

Go to URL
Optimization of Mass Drug Administration With Existing Drug Regimens for Lymphatic Filariasis and Onchocerciasis for Ivory Coast (DOLF-Ivory Coast)
 

Status: Recruiting

Condition Summary: Lymphatic Filariasis; Onchocerciasis; Soil Transmitted Helminth (STH) Infections

 

Last Updated: 21 Nov 2016

Go to URL