Onchocerciasis

Common Name(s)

Onchocerciasis

Onchocerciasis, also known as river blindness, is a parasitic disease affecting the eyes and skin caused by the parasitic worm Onchocerca volvulus. Onchocerciasis is transmitted to humans through bites of infected blackflies. These blackflies are common in fast-flowing rivers and streams, typically in remote villages nearby fertile land used for agriculture. Symptoms of Onchocerciasis include severe itching, skin lesions, the development of nodules under the skin, and eye lesions that can lead to visual impairment and permanent blindness. This disease occurs primarily in tropical areas, with almost all of the infected people living in sub-Saharan Africa. Cases of this disease have also appeared in Yemen and Latin America. There is currently no vaccine or medication available to prevent infection.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Onchocerciasis" for support, advocacy or research.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Onchocerciasis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Onchocerciasis" returned 314 free, full-text research articles on human participants. First 3 results:

Last Updated: 1 Nov 2016

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A Knowledge, Attitudes and Practices Survey Conducted Three Years after Halting Ivermectin Mass Treatment for Onchocerciasis in Guatemala.
 

Author(s): Frank O Richards, Robert E Klein, Oscar de León, Renata Mendizábal-Cabrera, Alba Lucía Morales, Vitaliano Cama, Carol G Crovella, Carlos E Díaz Espinoza, Zoraida Morales, Mauricio Sauerbrey, Nidia Rizzo

Journal:

 

Mass drug administration (MDA) with ivermectin for onchocerciasis was provided in Guatemala's Central Endemic Zone (CEZ) over a 24 year period (1988-2011). Elimination of Onchocerca volvulus transmission was declared in 2015 after a three year post MDA surveillance period (2012-2014) ...

Last Updated: 25 Jun 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Onchocerciasis" returned 20 free, full-text review articles on human participants. First 3 results:

Doxycycline plus ivermectin versus ivermectin alone for treatment of patients with onchocerciasis.
 

Author(s): Ayokunle T Abegunde, Richard M Ahuja, Nkem J Okafor

Journal:

 

Onchocerciasis, also known as "river blindness," is a parasitic disease that is caused by infection from the filarial nematode (roundworm), Onchocerca volvulus. Nematodes are transmitted from person to person by blackflies of the Simulium genus, which usually breed in fast flowing ...

Last Updated: 1 Feb 2016

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Contribution and performance of female Community-Directed Distributors in the treatment of onchocerciasis with Ivermectin in Sub-Saharan Africa: a systematic review.
 

Author(s): Marius Zambou Vouking, Violette Claire Tamo, Carine Nouboudem Tadenfok

Journal:

 

The African Program for Onchocerciasis Control (APOC) was launched in 1995 with the main goal being to boost the fight against onchocerciasis in Africa. In 2011, over 80 million people benefited from this intervention thanks to the contribution of 268.718 Community-Directed Distributors ...

Last Updated: 2 Oct 2015

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The Contributions of Onchocerciasis Control and Elimination Programs toward the Achievement of the Millennium Development Goals.
 

Author(s): Caitlin Dunn, Kelly Callahan, Moses Katabarwa, Frank Richards, Donald Hopkins, P Craig Withers, Lucas E Buyon, Deborah McFarland

Journal:

 

In 2000, 189 member states of the United Nations (UN) developed a plan for peace and development, which resulted in eight actionable goals known as the Millennium Development Goals (MDGs). Since their inception, the MDGs have been considered the international standard for measuring ...

Last Updated: 22 May 2015

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Efficacy of Ivermectin and Albendazole Against Onchocerciasis in the Volta Region, Ghana
 

Status: Not yet recruiting

Condition Summary: Onchocerciasis

 

Last Updated: 28 Feb 2014

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Ivermectin Treatment in Patients With Onchocerciasis-associated Epilepsy
 

Status: Not yet recruiting

Condition Summary: Ivermectin; Onchocerciasis; Epilepsy

 

Last Updated: 15 Feb 2017

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Mass Drug Administration for Lymphatic Filariasis and Onchocerciasis for Liberia
 

Status: Recruiting

Condition Summary: Lymphatic Filariasis; Onchocerciasis; Soil Transmitted Helminth (STH) Infections

 

Last Updated: 21 Nov 2016

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