Aortic Coarctation

Common Name(s)

Aortic Coarctation

Aortic coarctation describes narrowing of the aorta, the large blood vessel leaving the heart to deliver oxygen-rich blood to the body. This narrowing forces the heart to work harder to pump the blood. It is a congenital condition, meaning it is present at birth, but sometimes is mild enough that it is not detected until adulthood. In babies, symptoms include pale skin, irratibility, sweating, and difficulty breathing. This can cause life-threatening complications if left untreated. Often if the coarctation presents in adolescence or adulthood, it is less severe and simply causes hypertension (high blood pressure). Some people may also get muscle weakness, shortness of breath, headaches, and nose bleeds. One should go to the doctor if chest pain or very high blood pressure are present, as these syptoms raise the risk of stroke, organ failure, or death. The causes of coarctation are unknown, though it often associates with other heart defects or women with Turner syndome, a genetic syndrome caused by a error or mutation in the DNA. A doctor can disagnose coarctation through a chest x-ray or other imaging tests like an echocardiogram. Aortic coarctation and other defects that often come with it are treated with surgery and medications.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Aortic Coarctation" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Aortic Coarctation" returned 265 free, full-text research articles on human participants. First 3 results:

Fluid dynamics of coarctation of the aorta and effect of bicuspid aortic valve.
 

Author(s): Zahra Keshavarz-Motamed, Julio Garcia, Lyes Kadem

Journal:

 

Up to 80% of patients with coarctation of the aorta (COA) have a bicuspid aortic valve (BAV). Patients with COA and BAV have elevated risks of aortic complications despite successful surgical repair. The development of such complications involves the interplay between the mechanical ...

Last Updated: 9 Sep 2013

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Development of aortic coarctation following device closure of patent ductus arteriosus.
 

Author(s): Arpan R Doshi, P Syamasundar Rao

Journal: J Invasive Cardiol. 2013 Sep;25(9):464-7.

 

A patient who had transcatheter closure of a large patent ductus arteriosus in early infancy developed aortic coarctation during follow-up. Initially, balloon angioplasty and subsequent stent implantation successfully relieved the aortic obstruction. Avoidance of use of large devices ...

Last Updated: 2 Sep 2013

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Congenital absence of right pulmonary artery associated with left patent ductus arteriosus and aortic coarctation.
 

Author(s): Lan He, Fang Liu, Guo-ying Huang

Journal: Chin. Med. J.. 2013 Aug;126(16):3192.

 

Last Updated: 28 Aug 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Aortic Coarctation" returned 11 free, full-text review articles on human participants. First 3 results:

Technique of interventional repair in adult aortic coarctation.
 

Author(s): Stephan Kische, Henrik Schneider, Ibrahim Akin, Jasmin Ortak, Tim C Rehders, Tushar Chatterjee, Christoph A Nienaber, Hüseyin Ince

Journal: J. Vasc. Surg.. 2010 Jun;51(6):1550-9.

 

Surgical treatment of aortic coarctation has increased life expectancy and reduced mortality. Unfortunately, the average lifespan after repair remains only 35 to 50 years, and significant morbidity persists as a result of aneurysm formation, hypertension, accelerated coronary disease, ...

Last Updated: 21 May 2010

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Management of aortic coarctation in adults: endovascular versus surgical therapy.
 

Author(s): Aphrodite Anagnostopoulos-Tzifa

Journal: Hellenic J Cardiol. ;48(5):290-5.

 

Last Updated: 29 Oct 2007

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Dorsal pancreas agenesis and polysplenia/heterotaxy syndrome: a novel association with aortic coarctation and a review of the literature.
 

Author(s): Suraj Kapa, Ferga C Gleeson, Santhi Swaroop Vege

Journal:

 

Agenesis of the dorsal pancreas is very rare and may be associated with other congenital disease states. It has a rare association with polysplenia/heterotaxy syndrome. Most commonly, these states occur due to errors in development of the asymmetric organs and may be associated with ...

Last Updated: 12 Jul 2007

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Haemodynamics and Function of the Atria in Congenital Heart Disease by Cardiovascular Magnetic Resonance
 

Status: Recruiting

Condition Summary: Coarctation of the Aorta; Tetralogy of Fallot; Transposition of the Great Arteries

 

Last Updated: 10 Jun 2014

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Genetic Analysis of PHACE Syndrome (Hemangioma With Other Congenital Anomalies)
 

Status: Recruiting

Condition Summary: PHACE Syndrome

 

Last Updated: 31 Oct 2013

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