Aortic Coarctation

Common Name(s)

Aortic Coarctation

Aortic coarctation describes narrowing of the aorta, the large blood vessel leaving the heart to deliver oxygen-rich blood to the body. This narrowing forces the heart to work harder to pump the blood. It is a congenital condition, meaning it is present at birth, but sometimes is mild enough that it is not detected until adulthood. In babies, symptoms include pale skin, irratibility, sweating, and difficulty breathing. This can cause life-threatening complications if left untreated. Often if the coarctation presents in adolescence or adulthood, it is less severe and simply causes hypertension (high blood pressure). Some people may also get muscle weakness, shortness of breath, headaches, and nose bleeds. One should go to the doctor if chest pain or very high blood pressure are present, as these syptoms raise the risk of stroke, organ failure, or death. The causes of coarctation are unknown, though it often associates with other heart defects or women with Turner syndome, a genetic syndrome caused by a error or mutation in the DNA. A doctor can disagnose coarctation through a chest x-ray or other imaging tests like an echocardiogram. Aortic coarctation and other defects that often come with it are treated with surgery and medications.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Aortic Coarctation" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Aortic Coarctation" returned 345 free, full-text research articles on human participants. First 3 results:

Avoidable costs of stenting for aortic coarctation in the United Kingdom: an economic model.
 

Author(s): Maximilian Salcher, Alistair Mcguire, Vivek Muthurangu, Marcus Kelm, Titus Kuehne, Huseyin Naci,

Journal:

 

Undesirable outcomes in health care are associated with patient harm and substantial excess costs. Coarctation of the aorta (CoA), one of the most common congenital heart diseases, can be repaired with stenting but requires monitoring and subsequent interventions to detect and treat ...

Last Updated: 11 Apr 2017

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Beyond Pressure Gradients: The Effects of Intervention on Heart Power in Aortic Coarctation.
 

Author(s): Joao Filipe Fernandes, Leonid Goubergrits, Jan Brüning, Florian Hellmeier, Sarah Nordmeyer, Tiago Ferreira da Silva, Stephan Schubert, Felix Berger, Titus Kuehne, Marcus Kelm,

Journal:

 

In aortic coarctation, current guidelines recommend reducing pressure gradients that exceed given thresholds. From a physiological standpoint this should ideally improve the energy expenditure of the heart and thus prevent long term organ damage.

Last Updated: 12 Jan 2017

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Aortic coarctation disclosed in a middle-aged hypertensive patient by tardus parvus waveform in renal Doppler ultrasonography.
 

Author(s): Łukasz Stryczyński, Katarzyna Kostka-Jeziorny, Robert Juszkat, Andrzej Tykarski

Journal: Kardiol Pol. 2016 ;74(11):1355.

 

Last Updated: 2 Dec 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Aortic Coarctation" returned 13 free, full-text review articles on human participants. First 3 results:

Stent dilatation of atretic aortic coarctation in an adult-case report and literature review.
 

Author(s): Neerod Kumar Jha, Magdi Tofeig, Rajappan Arun Kumar, Amin ElTahir, Syed Mohammad Athar, Aref AlHakami, Arshad Khan, Mohammad Daud Khan

Journal:

 

Patients with functional aortic interruption of the descending thoracic aorta at the isthmus due to severe coarctation in association with atretic lumen are extremely rare in the adult population. The management is challenging and carries high morbidity and mortality.

Last Updated: 19 Jan 2016

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Aortic Wall Injury Related to Endovascular Therapy for Aortic Coarctation.
 

Author(s): Justin T Tretter, Thomas K Jones, Doff B McElhinney

Journal: Circ Cardiovasc Interv. 2015 Sep;8(9):e002840.

 

Aortic wall complications can occur in unrepaired aortic coarctation (CoA) and after surgical repair or endovascular treatment. This review summarizes the available literature and current understanding of aortic wall injury (AWI) surrounding the management of CoA, focusing specifically ...

Last Updated: 21 Aug 2015

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Technique of interventional repair in adult aortic coarctation.
 

Author(s): Stephan Kische, Henrik Schneider, Ibrahim Akin, Jasmin Ortak, Tim C Rehders, Tushar Chatterjee, Christoph A Nienaber, Hüseyin Ince

Journal: J. Vasc. Surg.. 2010 Jun;51(6):1550-9.

 

Surgical treatment of aortic coarctation has increased life expectancy and reduced mortality. Unfortunately, the average lifespan after repair remains only 35 to 50 years, and significant morbidity persists as a result of aneurysm formation, hypertension, accelerated coronary disease, ...

Last Updated: 21 May 2010

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 15 Jul 2016

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Long-term Outcomes and Vascular Evaluation After Coarctation of the Aorta Treatment
 

Status: Recruiting

Condition Summary: Aortic Coarctation; Arterial Stiffness; PULSE WAVE VELOCITY; Functional Magnetic Resonance Imaging; Vascular Endothelium

 

Last Updated: 24 Aug 2017

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Haemodynamics and Function of the Atria in Congenital Heart Disease by Cardiovascular Magnetic Resonance
 

Status: Recruiting

Condition Summary: Coarctation of the Aorta; Tetralogy of Fallot; Transposition of the Great Arteries

 

Last Updated: 12 Oct 2016

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