Aortic Coarctation

Common Name(s)

Aortic Coarctation

Aortic coarctation describes narrowing of the aorta, the large blood vessel leaving the heart to deliver oxygen-rich blood to the body. This narrowing forces the heart to work harder to pump the blood. It is a congenital condition, meaning it is present at birth, but sometimes is mild enough that it is not detected until adulthood. In babies, symptoms include pale skin, irratibility, sweating, and difficulty breathing. This can cause life-threatening complications if left untreated. Often if the coarctation presents in adolescence or adulthood, it is less severe and simply causes hypertension (high blood pressure). Some people may also get muscle weakness, shortness of breath, headaches, and nose bleeds. One should go to the doctor if chest pain or very high blood pressure are present, as these syptoms raise the risk of stroke, organ failure, or death. The causes of coarctation are unknown, though it often associates with other heart defects or women with Turner syndome, a genetic syndrome caused by a error or mutation in the DNA. A doctor can disagnose coarctation through a chest x-ray or other imaging tests like an echocardiogram. Aortic coarctation and other defects that often come with it are treated with surgery and medications.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Aortic Coarctation" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Aortic Coarctation" returned 348 free, full-text research articles on human participants. First 3 results:

Axillofemoral Bypass Markedly Improved Acute Decompensated Heart Failure and Kidney Injury in a Patient with Severely Calcified Stenosis of Thoracoabdominal Aorta (Atypical Aortic Coarctation).
 

Author(s): Masato Ishizuka, Shintaro Yamada, Sonoko Maemura, Keisuke Yamamoto, Masataka Takizawa, Hiroki Uozumi, Sachito Minegishi, Jotaro Kobayashi, Hiroshi Ikenouchi

Journal: Int Heart J. 2017 Oct;58(5):820-823.

 

Atypical aortic coarctation (AAC) has been reported to occur anywhere along the aorta, except for the ascending aorta. The associated symptoms include hypotension in the lower half of the body, secondary hypertension in the upper half of the body, and heart failure. Here we present ...

Last Updated: 2 Oct 2017

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Avoidable costs of stenting for aortic coarctation in the United Kingdom: an economic model.
 

Author(s): Maximilian Salcher, Alistair Mcguire, Vivek Muthurangu, Marcus Kelm, Titus Kuehne, Huseyin Naci,

Journal:

 

Undesirable outcomes in health care are associated with patient harm and substantial excess costs. Coarctation of the aorta (CoA), one of the most common congenital heart diseases, can be repaired with stenting but requires monitoring and subsequent interventions to detect and treat ...

Last Updated: 11 Apr 2017

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Beyond Pressure Gradients: The Effects of Intervention on Heart Power in Aortic Coarctation.
 

Author(s): Joao Filipe Fernandes, Leonid Goubergrits, Jan BrĂ¼ning, Florian Hellmeier, Sarah Nordmeyer, Tiago Ferreira da Silva, Stephan Schubert, Felix Berger, Titus Kuehne, Marcus Kelm,

Journal:

 

In aortic coarctation, current guidelines recommend reducing pressure gradients that exceed given thresholds. From a physiological standpoint this should ideally improve the energy expenditure of the heart and thus prevent long term organ damage.

Last Updated: 12 Jan 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Aortic Coarctation" returned 15 free, full-text review articles on human participants. First 3 results:

Endovascular Exclusion of Aortobronchial Fistula and Distal Anastomotic Aneurysm after Extra-Anatomic Bypass for Aortic Coarctation.
 

Author(s): Antonio Bozzani, Vittorio Arici, Giuseppe Rodolico, Massimo Borri Brunetto, Angelo Argenteri

Journal:

 

The treatment of choice for aortic coarctation in adults remains open surgical repair. Aortobronchial fistula is a rare but potentially fatal late sequela of surgical correction of isthmic aortic coarctation via the interposition of a graft. The endovascular treatment of aortobronchial ...

Last Updated: 7 Mar 2017

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Multimodality imaging of aortic coarctation: From the fetus to the adolescent.
 

Author(s): P Gach, A Dabadie, C Sorensen, E Quarello, B Bonello, H Pico, N Hugues, P Petit, G Gorincour

Journal: Diagn Interv Imaging. 2016 May;97(5):581-90.

 

Aortic coarctation is a local narrowing of the aortic lumen, which is located at the level of the isthmus in 95% of patients. Aortic coarctation accounts for 5 to 8% of all congenital heart diseases. It may have an acute presentation in the form of heart failure in the neonate or ...

Last Updated: 16 May 2016

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Stent dilatation of atretic aortic coarctation in an adult-case report and literature review.
 

Author(s): Neerod Kumar Jha, Magdi Tofeig, Rajappan Arun Kumar, Amin ElTahir, Syed Mohammad Athar, Aref AlHakami, Arshad Khan, Mohammad Daud Khan

Journal:

 

Patients with functional aortic interruption of the descending thoracic aorta at the isthmus due to severe coarctation in association with atretic lumen are extremely rare in the adult population. The management is challenging and carries high morbidity and mortality.

Last Updated: 19 Jan 2016

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 15 Jul 2016

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Antenatal Diagnosis of Coarctations of the Aorta.
 

Status: Not yet recruiting

Condition Summary: Coarctation of Aorta

 

Last Updated: 5 Oct 2017

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Long-term Outcomes and Vascular Evaluation After Coarctation of the Aorta Treatment
 

Status: Recruiting

Condition Summary: Aortic Coarctation; Arterial Stiffness; PULSE WAVE VELOCITY; Functional Magnetic Resonance Imaging; Vascular Endothelium

 

Last Updated: 24 Aug 2017

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