Ocular melanoma

Common Name(s)

Ocular melanoma

Ocular melanoma (OM) is a cancer in pigment-producing cells of the eye called melanocytes.   Melanocytes are cells that produce the pigment melanin that colors the skin, hair, and eyes, as well as forms moles.  There are four tissues in the eye in which melanoma can develop: the uveal tract (uvea); conjunctiva; eyelid; and orbit.  The uvea - the middle layer within the eye  - is divided into three main parts: the iris, ciliary body, and choroid.  Uveal melanoma, also called intraocular melanoma, is the most common ocular melanoma. Conjunctival melanoma manifests on the surface of the eye and has been increasing in incidence. Eyelid and primary orbiatl melanoma are the least common variants.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Ocular melanoma" for support, advocacy or research.

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Ocular Melanoma Foundation

OMF’s mission is to accelerate and enhance scientific research, advocacy, and awareness of ocular melanoma and to provide education and support to patients, their families, and healthcare professionals.

Last Updated: 20 Feb 2013

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Ocular melanoma" for support, advocacy or research.

Logo
Ocular Melanoma Foundation

OMF’s mission is to accelerate and enhance scientific research, advocacy, and awareness of ocular melanoma and to provide education and support to patients, their families, and healthcare professionals.

http://www.ocularmelanoma.org/

Last Updated: 20 Feb 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Ocular melanoma" returned 91 free, full-text research articles on human participants. First 3 results:

Pancreatic metastases from ocular malignant melanoma: the use of endoscopic ultrasound-guided fine-needle aspiration to establish a definitive cytologic diagnosis: a case report.
 

Author(s): Diogo Turiani Hourneaux De Moura, Danielle Azevedo Chacon, Ryan Tanigawa, Martin Coronel, Spencer Cheng, Éverson L A Artifon, José Jukemura, Eduardo Guimarães Hourneaux De Moura

Journal:

 

When encountering solid pancreatic lesions, nonpancreatic primary metastases are rare and differentiating a metastasis from a primary neoplastic lesion is challenging. The clinical presentation and radiologic features can be similar and the possibility of a pancreatic metastasis should ...

Last Updated: 1 Dec 2016

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Metastatic melanoma after 23 years of primary ocular melanoma.
 

Author(s): Supriya Ramesh Karde, Prashant Ramesh Bhand, Nagabathula Ramesh, Sacchin Arockiam

Journal:

 

We describe a case of 52-year-old man who presented with an episode of tonic-clonic seizures. He had right ocular melanoma 23 years ago with subsequent enucleation which was the standard treatment at that time. CT scans of the brain and of the thorax-abdomen-pelvis revealed widespread ...

Last Updated: 24 Nov 2016

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A challenging case of ocular melanoma.
 

Author(s): Mariana Costache, Adrian Vasile Dumitru, Oana Maria Pătraşcu, Daniela Alina Popa-Cherecheanu, Patricia Bădilă, Jeni Cătălina Miu, Alexandru Procop, Manuela Popa, Mircea Ştefan Tampa, Maria Sajin, Olga Simionescu, Monica Mihaela Cîrstoiu

Journal: Rom J Morphol Embryol. 2015 ;56(2 Suppl):817-22.

 

Ocular melanoma is a rare malignancy found in clinical practice. In this paper, we present a case of highly aggressive ocular melanoma, which was surgically removed at the Department of Ophthalmology and diagnosed at the Department of Pathology, Emergency University Hospital, Bucharest, ...

Last Updated: 2 Oct 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Ocular melanoma" returned 5 free, full-text review articles on human participants. First 3 results:

Proton therapy for the management of uveal melanoma and other ocular tumors.
 

Author(s): Kavita K Mishra, Inder K Daftari

Journal: Chin Clin Oncol. 2016 Aug;5(4):50.

 

Proton beam radiotherapy of uveal melanoma and other malignant and benign ocular tumors has shown tremendous development and success over the past four decades. Proton beam is associated with the lowest overall risk of local tumor recurrence in uveal melanoma, compared with other ...

Last Updated: 25 Aug 2016

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Ocular melanoma: an overview of the current status.
 

Author(s): Predrag Jovanovic, Marija Mihajlovic, Jasmina Djordjevic-Jocic, Slobodan Vlajkovic, Sonja Cekic, Vladisav Stefanovic

Journal:

 

Ocular melanoma is the second most common type of melanoma after cutaneous and the most common primary intraocular malignant tumor in adults. Large majority of ocular melanomas originate from uvea, while conjunctival melanomas are far less frequent. Incidence of uveal melanoma has ...

Last Updated: 4 Jul 2013

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Does ocular treatment of uveal melanoma influence survival?
 

Author(s): B Damato

Journal: Br. J. Cancer. 2010 Jul;103(3):285-90.

 

Treatment of uveal (intraocular) melanoma is aimed at prolonging life, if possible conserving the eye and useful vision. About 50% of patients develop fatal metastatic disease despite successful eradication of the primary intraocular tumour. The effect of ocular treatment on survival ...

Last Updated: 27 Jul 2010

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 2 Jul 2013

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Definity for Ultrasound of Intraocular Tumors
 

Status: Not yet recruiting

Condition Summary: Ocular Melanoma

 

Last Updated: 24 Feb 2017

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