Obsessive Compulsive Disorder

Common Name(s)

Obsessive Compulsive Disorder

Obsessive-compulsive disorder (OCD) is a lifelong condition where unreasonable thoughts and fears, or obsessions, lead a person to do repetitive behaviors, or compulsions. A person with OCD may or may not realize that their obsessions are unreasonable. A primary symptom of OCD is the presence of obsessions, which are repeated, persistent and unwanted urges that cause distress or anxiety. OCD obsessions often center on themes, such as fear of contamination, having things orderly/symmetric, or thoughts regarding harming oneself or others. Another symptom is the presence of compulsions, which are repetitive behavior that a person with OCD feels like they have to perform. Completing these repetitive behaviors are meant to prevent or reduce anxiety and prevent something bad from happening. Compulsions also follow themes like washing and cleaning, counting, checking, demanding reassurances and following a routine. Usually OCD is made up of both obsessions and compulsions, but it’s possible to only experience one. The general criteria to diagnose OCD is the person has obsessions and/or compulsions and these obsessions/compulsions are time-consuming and interfere with daily life. OCD has no cure, but symptoms can be controlled using exposure therapy and medication.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Obsessive Compulsive Disorder" for support, advocacy or research.

International OCD Foundation

Founded by a group of people with OCD in 1986, the International OCD Foundation (IOCDF) is an international not-for-profit organization made up of people with Obsessive Compulsive Disorder (OCD) and related disorders, as well as their families, friends, professionals and others. The mission and goals of the IOCDF are to: Educate the public and professionals about OCD in order to raise awareness and improve the quality of treatment provided; Support research into the cause of, and effective treatments for, OCD and related disorders; Improve access to resources for those with OCD and their fam

Last Updated: 19 Feb 2013

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National Alliance on Mental Illness

NAMI is the National Alliance on Mental Illness, the nation's largest grassroots mental health organization dedicated to building better lives for the millions of Americans affected by mental illness. NAMI, NAMI State Organizations and hundreds of local NAMI Affiliates advocate for access to services, treatment, supports and research and are committed to raising awareness and building a community of hope for all of those in need.

Last Updated: 29 Jan 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Obsessive Compulsive Disorder" for support, advocacy or research.

International OCD Foundation

Founded by a group of people with OCD in 1986, the International OCD Foundation (IOCDF) is an international not-for-profit organization made up of people with Obsessive Compulsive Disorder (OCD) and related disorders, as well as their families, friends, professionals and others. The mission and goals of the IOCDF are to: Educate the public and professionals about OCD in order to raise awareness and improve the quality of treatment provided; Support research into the cause of, and effective treatments for, OCD and related disorders; Improve access to resources for those with OCD and their fam

http://www.ocfoundation.org

Last Updated: 19 Feb 2013

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National Alliance on Mental Illness

NAMI is the National Alliance on Mental Illness, the nation's largest grassroots mental health organization dedicated to building better lives for the millions of Americans affected by mental illness. NAMI, NAMI State Organizations and hundreds of local NAMI Affiliates advocate for access to services, treatment, supports and research and are committed to raising awareness and building a community of hope for all of those in need.

http://www.nami.org

Last Updated: 29 Jan 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Obsessive Compulsive Disorder" returned 388 free, full-text research articles on human participants. First 3 results:

Obsessive-compulsive disorder in fathers during pregnancy and postpartum.
 

Author(s): Fábio M Coelho, Ricardo A da Silva, Luciana de Á Quevedo, Luciano D Souza, Karen A Pinheiro, Ricardo T Pinheiro

Journal: Rev Bras Psiquiatr. 2014 Sep;36(3):271-3.

 

Last Updated: 14 Aug 2014

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Aberrant error processing in relation to symptom severity in obsessive-compulsive disorder: A multimodal neuroimaging study.
 

Author(s): Yigal Agam, Jennifer L Greenberg, Marlisa Isom, Martha J Falkenstein, Eric Jenike, Sabine Wilhelm, Dara S Manoach

Journal:

 

Obsessive-compulsive disorder (OCD) is characterized by maladaptive repetitive behaviors that persist despite feedback. Using multimodal neuroimaging, we tested the hypothesis that this behavioral rigidity reflects impaired use of behavioral outcomes (here, errors) to adaptively adjust ...

Last Updated: 24 Jul 2014

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Internet-based cognitive bias modification for obsessive compulsive disorder: study protocol for a randomized controlled trial.
 

Author(s): Alishia D Williams, Rosanna Pajak, Kathleen O'Moore, Gavin Andrews, Jessica R Grisham

Journal:

 

Cognitive bias modification (CBM) interventions have demonstrated efficacy in augmenting core biases implicated in psychopathology. The current randomized controlled trial (RCT) will evaluate the efficacy of an internet-delivered positive imagery cognitive bias modification intervention ...

Last Updated: 11 Jun 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Obsessive Compulsive Disorder" returned 77 free, full-text review articles on human participants. First 3 results:

[Anxiety, obsessive-compulsive disorder and trauma in the DSM-5].
 

Author(s): A J L M van Balkom, L Gabriëls, O A van den Heuvel

Journal: Tijdschr Psychiatr. 2014 ;56(3):177-81.

 

The 12 anxiety disorders which were defined in the DSM-IV, have been increased to 27 disorders in the DSM-5. These 27 disorders have been subdivided into three chapters: 1. anxiety disorders, 2. obsessive-compulsive and related disorders (OCRD) and 3. trauma and stressor-related disorders.

Last Updated: 19 Mar 2014

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Excluding the typical patient: thirty years of pharmacotherapy efficacy trials for obsessive-compulsive disorder.
 

Author(s): Brian L Odlaug, Eric Weinhandl, Maria C Mancebo, Erik L Mortensen, Jane L Eisen, Steven A Rasmussen, Liana R N Schreiber, Jon E Grant

Journal: Ann Clin Psychiatry. 2014 Feb;26(1):39-46.

 

Over the past 30 years, clinical trials have resulted in several successful pharmacotherapies for obsessive-compulsive disorder (OCD), yet patients in clinical settings often report inadequate response. This study compares clinical characteristics of treatment-seeking OCD patients ...

Last Updated: 6 Feb 2014

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Deep brain stimulation for the treatment of severe, medically refractory obsessive-compulsive disorder.
 

Author(s): Mark Sedrak, William Wong, Paul Wilson, Diana Bruce, Ivan Bernstein, Suketu Khandhar, Conrad Pappas, Gary Heit, Eric Sabelman

Journal: Perm J. 2013 ;17(4):47-51.

 

Deep brain stimulation is a rapidly expanding therapy initially designed for the treatment of movement disorders and pain syndromes. The therapy includes implantation of electrodes in specific targets of the brain, delivering programmable small and safe electric impulses, like a pacemaker, ...

Last Updated: 23 Dec 2013

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 4 Mar 2013

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Attention Training for Childhood Obsessive Compulsive Disorder
 

Status: Recruiting

Condition Summary: Obsessive Compulsive Disorder

 

Last Updated: 12 Dec 2014

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Intravenous Ketamine in the Treatment of Obsessive-Compulsive Disorder
 

Status: Recruiting

Condition Summary: Obsessive Compulsive Disorder

 

Last Updated: 3 Nov 2014

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