Obsessive Compulsive Disorder

Common Name(s)

Obsessive Compulsive Disorder, OCD

Obsessive-compulsive disorder (OCD) is a lifelong condition where unreasonable thoughts and fears, or obsessions, lead a person to do repetitive behaviors, or compulsions. A person with OCD may or may not realize that their obsessions are unreasonable. A primary symptom of OCD is the presence of obsessions, which are repeated, persistent and unwanted urges that cause distress or anxiety. OCD obsessions often center on themes, such as fear of contamination, having things orderly/symmetric, or thoughts regarding harming oneself or others. Another symptom is the presence of compulsions, which are repetitive behavior that a person with OCD feels like they have to perform. Completing these repetitive behaviors are meant to prevent or reduce anxiety and prevent something bad from happening. Compulsions also follow themes like washing and cleaning, counting, checking, demanding reassurances and following a routine. Usually OCD is made up of both obsessions and compulsions, but it’s possible to only experience one. The general criteria to diagnose OCD is the person has obsessions and/or compulsions and these obsessions/compulsions are time-consuming and interfere with daily life. OCD has no cure, but symptoms can be controlled using exposure therapy and medication.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Obsessive Compulsive Disorder" for support, advocacy or research.

International OCD Foundation

Founded by a group of people with OCD in 1986, the International OCD Foundation (IOCDF) is an international not-for-profit organization made up of people with Obsessive Compulsive Disorder (OCD) and related disorders, as well as their families, friends, professionals and others. The mission and goals of the IOCDF are to: Educate the public and professionals about OCD in order to raise awareness and improve the quality of treatment provided; Support research into the cause of, and effective treatments for, OCD and related disorders; Improve access to resources for those with OCD and their fam

Last Updated: 19 Feb 2013

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National Alliance on Mental Illness

NAMI is the National Alliance on Mental Illness, the nation's largest grassroots mental health organization dedicated to building better lives for the millions of Americans affected by mental illness. NAMI, NAMI State Organizations and hundreds of local NAMI Affiliates advocate for access to services, treatment, supports and research and are committed to raising awareness and building a community of hope for all of those in need.

Last Updated: 6 Apr 2015

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Obsessive Compulsive Disorder" for support, advocacy or research.

International OCD Foundation

Founded by a group of people with OCD in 1986, the International OCD Foundation (IOCDF) is an international not-for-profit organization made up of people with Obsessive Compulsive Disorder (OCD) and related disorders, as well as their families, friends, professionals and others. The mission and goals of the IOCDF are to: Educate the public and professionals about OCD in order to raise awareness and improve the quality of treatment provided; Support research into the cause of, and effective treatments for, OCD and related disorders; Improve access to resources for those with OCD and their fam

http://www.ocfoundation.org

Last Updated: 19 Feb 2013

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National Alliance on Mental Illness

NAMI is the National Alliance on Mental Illness, the nation's largest grassroots mental health organization dedicated to building better lives for the millions of Americans affected by mental illness. NAMI, NAMI State Organizations and hundreds of local NAMI Affiliates advocate for access to services, treatment, supports and research and are committed to raising awareness and building a community of hope for all of those in need.

http://www.nami.org

Last Updated: 6 Apr 2015

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Obsessive Compulsive Disorder" returned 469 free, full-text research articles on human participants. First 3 results:

Anticipated reward in obsessive-compulsive disorder: are compulsions rewarding?
 

Author(s): Leonardo F Fontenelle, Sanne Oostermeijer, Gabriela Mourão Ferreira, Valentina Lorenzetti, Judy Luigjes, Murat Yücel

Journal: J Clin Psychiatry. 2015 Sep;76(9):e1134-5.

 

Last Updated: 12 Oct 2015

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What to make of misidentification rates in obsessive-compulsive disorder.
 

Author(s): Eric A Storch

Journal: J Clin Psychiatry. 2015 Jun;76(6):e820-1.

 

Last Updated: 3 Jul 2015

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Comparative Study of Neurological Soft Signs in Patients with Schizophrenia or Obsessive-compulsive Disorder, and Healthy Controls.
 

Author(s): R Tripathi, A Soni, A Tyagi, S Mehta, S Gupta

Journal: East Asian Arch Psychiatry. 2015 Jun;25(2):64-72.

 

The primary objective of this study was to examine neurological soft signs in patients with obsessive-compulsive disorder compared with patients with schizophrenia and a control group in the Indian setting. The secondary objective was to find any correlation between age at onset and ...

Last Updated: 29 Jun 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Obsessive Compulsive Disorder" returned 96 free, full-text review articles on human participants. First 3 results:

D-cycloserine augmentation in behavioral therapy for obsessive-compulsive disorder: a meta-analysis.
 

Author(s): Jing Xia, Yanqiu Du, Jiyang Han, Guo Liu, Xumei Wang

Journal:

 

To evaluate the overall effect of D-cycloserine (DCS) augmentation on exposure and response prevention (ERP) therapy for obsessive-compulsive disorder (OCD).

Last Updated: 11 May 2015

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Atypical antipsychotic augmentation in SSRI treatment refractory obsessive-compulsive disorder: a systematic review and meta-analysis.
 

Author(s): David Veale, Sarah Miles, Nicola Smallcombe, Haben Ghezai, Ben Goldacre, John Hodsoll

Journal:

 

In 2006, the National Institute of Clinical and Health Excellence (NICE) guidelines for Obsessive Compulsive Disorder (OCD) recommended anti-psychotics as a class for SSRI treatment resistant OCD. The article aims to systematically review and conduct a meta-analysis on the clinical ...

Last Updated: 27 Apr 2015

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Obsessive-compulsive disorder in children and adolescents.
 

Author(s): Georgina Krebs, Isobel Heyman

Journal: Arch. Dis. Child.. 2015 May;100(5):495-9.

 

Obsessive-compulsive disorder (OCD) in childhood and adolescence is an impairing condition, associated with a specific set of distressing symptoms incorporating repetitive, intrusive thoughts (obsessions) and distressing, time-consuming rituals (compulsions). This review considers ...

Last Updated: 18 Apr 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 4 Mar 2013

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Pharmacogenetic Study of Obsessive-Compulsive Disorder
 

Status: Recruiting

Condition Summary: Obsessive-Compulsive Disorder

 

Last Updated: 16 Nov 2015

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Effect of Mindfulness Based Treatment for Obsessive-compulsive Disorder
 

Status: Recruiting

Condition Summary: Obsessive-compulsive Disorder

 

Last Updated: 4 Dec 2013

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