Obsessive Compulsive Disorder

Common Name(s)

Obsessive Compulsive Disorder, OCD

Obsessive-compulsive disorder (OCD) is a lifelong condition where unreasonable thoughts and fears, or obsessions, lead a person to do repetitive behaviors, or compulsions. A person with OCD may or may not realize that their obsessions are unreasonable. A primary symptom of OCD is the presence of obsessions, which are repeated, persistent and unwanted urges that cause distress or anxiety. OCD obsessions often center on themes, such as fear of contamination, having things orderly/symmetric, or thoughts regarding harming oneself or others. Another symptom is the presence of compulsions, which are repetitive behavior that a person with OCD feels like they have to perform. Completing these repetitive behaviors are meant to prevent or reduce anxiety and prevent something bad from happening. Compulsions also follow themes like washing and cleaning, counting, checking, demanding reassurances and following a routine. Usually OCD is made up of both obsessions and compulsions, but it’s possible to only experience one. The general criteria to diagnose OCD is the person has obsessions and/or compulsions and these obsessions/compulsions are time-consuming and interfere with daily life. OCD has no cure, but symptoms can be controlled using exposure therapy and medication.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Obsessive Compulsive Disorder" for support, advocacy or research.

International OCD Foundation

Founded by a group of people with OCD in 1986, the International OCD Foundation (IOCDF) is an international not-for-profit organization made up of people with Obsessive Compulsive Disorder (OCD) and related disorders, as well as their families, friends, professionals and others. The mission and goals of the IOCDF are to: Educate the public and professionals about OCD in order to raise awareness and improve the quality of treatment provided; Support research into the cause of, and effective treatments for, OCD and related disorders; Improve access to resources for those with OCD and their fam

Last Updated: 19 Feb 2013

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National Alliance on Mental Illness

NAMI is the National Alliance on Mental Illness, the nation's largest grassroots mental health organization dedicated to building better lives for the millions of Americans affected by mental illness. NAMI, NAMI State Organizations and hundreds of local NAMI Affiliates advocate for access to services, treatment, supports and research and are committed to raising awareness and building a community of hope for all of those in need.

Last Updated: 6 Apr 2015

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Obsessive Compulsive Disorder" for support, advocacy or research.

International OCD Foundation

Founded by a group of people with OCD in 1986, the International OCD Foundation (IOCDF) is an international not-for-profit organization made up of people with Obsessive Compulsive Disorder (OCD) and related disorders, as well as their families, friends, professionals and others. The mission and goals of the IOCDF are to: Educate the public and professionals about OCD in order to raise awareness and improve the quality of treatment provided; Support research into the cause of, and effective treatments for, OCD and related disorders; Improve access to resources for those with OCD and their fam

http://www.ocfoundation.org

Last Updated: 19 Feb 2013

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National Alliance on Mental Illness

NAMI is the National Alliance on Mental Illness, the nation's largest grassroots mental health organization dedicated to building better lives for the millions of Americans affected by mental illness. NAMI, NAMI State Organizations and hundreds of local NAMI Affiliates advocate for access to services, treatment, supports and research and are committed to raising awareness and building a community of hope for all of those in need.

http://www.nami.org

Last Updated: 6 Apr 2015

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Obsessive Compulsive Disorder" returned 590 free, full-text research articles on human participants. First 3 results:

Cognitive psychopathology in Schizophrenia: Comparing memory performances with Obsessive-compulsive disorder patients and normal subjects on the Wechsler Memory Scale-IV.
 

Author(s): Davide Maria Cammisuli, Marco Timpano Sportiello

Journal: Psychiatr Danub. 2016 Jun;28(2):118-26.

 

Memory system turns out to be one of the cognitive domains most severely impaired in schizophrenia. Within the theoretical framework of cognitive psychopathology, we compared the performance of schizophrenia patients on the Wechsler Memory Scale-IV with that in matched patients with ...

Last Updated: 11 Jun 2016

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Integrating Genetic, Neuropsychological and Neuroimaging Data to Model Early-Onset Obsessive Compulsive Disorder Severity.
 

Author(s): Sergi Mas, Patricia Gassó, Astrid Morer, Anna Calvo, Nuria Bargalló, Amalia Lafuente, Luisa Lázaro

Journal:

 

We propose an integrative approach that combines structural magnetic resonance imaging data (MRI), diffusion tensor imaging data (DTI), neuropsychological data, and genetic data to predict early-onset obsessive compulsive disorder (OCD) severity. From a cohort of 87 patients, 56 with ...

Last Updated: 20 Apr 2016

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The Risk of Cancer in Patients With Obsessive-Compulsive Disorder: A Nationwide Population-Based Retrospective Cohort Study.
 

Author(s): Cheng-Che Shen, Li-Yu Hu, Yu-Wen Hu, Wen-Han Chang, Pei-Ling Tang, Pan-Ming Chen, Tzeng-Ji Chen, Tung-Ping Su

Journal: Medicine (Baltimore). 2016 Mar;95(9):e2989.

 

Previous studies suggest a link between anxiety disorders and cancer. The aim of the study was to evaluate the risk of cancer among patients with obsessive-compulsive disorder (OCD) using a nationwide population-based dataset. We recruited newly diagnosed OCD patients without antecedent ...

Last Updated: 6 Mar 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Obsessive Compulsive Disorder" returned 117 free, full-text review articles on human participants. First 3 results:

Pharmacotherapy of obsessive-compulsive disorder during pregnancy: a clinical approach.
 

Author(s): Faruk Uguz

Journal: Rev Bras Psiquiatr. ;37(4):334-42.

 

Obsessive-compulsive disorder (OCD) is a relatively common psychiatric disorder in the perinatal period. However, specific pharmacological treatment approaches for patients with OCD during pregnancy have not been satisfactorily discussed in the literature. In addition, there are no ...

Last Updated: 22 Dec 2015

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The overlap between anxiety, depression, and obsessive-compulsive disorder.
 

Author(s): Guy M Goodwin

Journal: Dialogues Clin Neurosci. 2015 Sep;17(3):249-60.

 

The anxiety disorders include generalized anxiety disorder, specific phobia, social phobia, agoraphobia, and panic disorder. In addition to the specific symptoms of these disorders, there may be a common experience of anxiety and even dysphoria across the conditions, and of course ...

Last Updated: 21 Oct 2015

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Comorbidity Between Attention Deficit/Hyperactivity Disorder and Obsessive-Compulsive Disorder Across the Lifespan: A Systematic and Critical Review.
 

Author(s): Amitai Abramovitch, Reuven Dar, Andrew Mittelman, Sabine Wilhelm

Journal: Harv Rev Psychiatry. ;23(4):245-62.

 

The concept of comorbidity between attention deficit/hyperactivity disorder (ADHD) and obsessive-compulsive disorder (OCD) has been discussed for two decades. No review, however, has examined this question in light of the stark contrast in disorder-specific phenomenology and neurobiology. ...

Last Updated: 7 Jul 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Pharmacogenetic Study of Obsessive-Compulsive Disorder
 

Status: Recruiting

Condition Summary: Obsessive-Compulsive Disorder

 

Last Updated: 16 Nov 2015

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N-acetylcysteine (NAC) for Pediatric Obsessive-Compulsive Disorder
 

Status: Recruiting

Condition Summary: Obsessive-Compulsive Disorder

 

Last Updated: 1 Sep 2016

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Deep Brain Stimulation of NAc/ALIC to Prevent Treatment-Refractory Obsessive Compulsive Disorder
 

Status: Not yet recruiting

Condition Summary: Obsessive Compulsive Disorder

 

Last Updated: 9 Nov 2015

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