Obsessive Compulsive Disorder

Common Name(s)

Obsessive Compulsive Disorder, OCD

Obsessive-compulsive disorder (OCD) is a lifelong condition where unreasonable thoughts and fears, or obsessions, lead a person to do repetitive behaviors, or compulsions. A person with OCD may or may not realize that their obsessions are unreasonable. A primary symptom of OCD is the presence of obsessions, which are repeated, persistent and unwanted urges that cause distress or anxiety. OCD obsessions often center on themes, such as fear of contamination, having things orderly/symmetric, or thoughts regarding harming oneself or others. Another symptom is the presence of compulsions, which are repetitive behavior that a person with OCD feels like they have to perform. Completing these repetitive behaviors are meant to prevent or reduce anxiety and prevent something bad from happening. Compulsions also follow themes like washing and cleaning, counting, checking, demanding reassurances and following a routine. Usually OCD is made up of both obsessions and compulsions, but it’s possible to only experience one. The general criteria to diagnose OCD is the person has obsessions and/or compulsions and these obsessions/compulsions are time-consuming and interfere with daily life. OCD has no cure, but symptoms can be controlled using exposure therapy and medication.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Obsessive Compulsive Disorder" for support, advocacy or research.

International OCD Foundation

Founded by a group of people with OCD in 1986, the International OCD Foundation (IOCDF) is an international not-for-profit organization made up of people with Obsessive Compulsive Disorder (OCD) and related disorders, as well as their families, friends, professionals and others. The mission and goals of the IOCDF are to: Educate the public and professionals about OCD in order to raise awareness and improve the quality of treatment provided; Support research into the cause of, and effective treatments for, OCD and related disorders; Improve access to resources for those with OCD and their fam

Last Updated: 19 Feb 2013

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National Alliance on Mental Illness

NAMI is the National Alliance on Mental Illness, the nation's largest grassroots mental health organization dedicated to building better lives for the millions of Americans affected by mental illness. NAMI, NAMI State Organizations and hundreds of local NAMI Affiliates advocate for access to services, treatment, supports and research and are committed to raising awareness and building a community of hope for all of those in need.

Last Updated: 6 Apr 2015

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Obsessive Compulsive Disorder" for support, advocacy or research.

International OCD Foundation

Founded by a group of people with OCD in 1986, the International OCD Foundation (IOCDF) is an international not-for-profit organization made up of people with Obsessive Compulsive Disorder (OCD) and related disorders, as well as their families, friends, professionals and others. The mission and goals of the IOCDF are to: Educate the public and professionals about OCD in order to raise awareness and improve the quality of treatment provided; Support research into the cause of, and effective treatments for, OCD and related disorders; Improve access to resources for those with OCD and their fam

http://www.ocfoundation.org

Last Updated: 19 Feb 2013

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National Alliance on Mental Illness

NAMI is the National Alliance on Mental Illness, the nation's largest grassroots mental health organization dedicated to building better lives for the millions of Americans affected by mental illness. NAMI, NAMI State Organizations and hundreds of local NAMI Affiliates advocate for access to services, treatment, supports and research and are committed to raising awareness and building a community of hope for all of those in need.

http://www.nami.org

Last Updated: 6 Apr 2015

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Obsessive Compulsive Disorder" returned 410 free, full-text research articles on human participants. First 3 results:

Reward-based spatial learning in unmedicated adults with obsessive-compulsive disorder.
 

Author(s): Rachel Marsh, Gregory Z Tau, Zhishun Wang, Yuankai Huo, Ge Liu, Xuejun Hao, Mark G Packard, Bradley S Peterson, H Blair Simpson

Journal: Am J Psychiatry. 2015 Apr;172(4):383-92.

 

The authors assessed the functioning of mesolimbic and striatal areas involved in reward-based spatial learning in unmedicated adults with obsessive-compulsive disorder (OCD).

Last Updated: 1 Apr 2015

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Microstructural abnormality in left nucleus accumbens predicts dysfunctional beliefs in treatment-resistant obsessive-compulsive disorder.
 

Author(s): Zhongchun Li, Weidong Ji, Deqiang Li, Xujuan Li, Wei Feng

Journal:

 

The aim of this study was to determine whether dysfunctional beliefs might predict treatment-resistance and to examine the relationship between fractional anisotropy (FA) in diffusion tensor imaging (DTI) and cognitive biases for optimal treatment choice.

Last Updated: 14 Nov 2014

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Obsessive-compulsive (anankastic) personality disorder: toward the ICD-11 classification.
 

Author(s): Naomi A Fineberg, Samar Reghunandanan, Sangeetha Kolli, Murad Atmaca

Journal: Rev Bras Psiquiatr. 2014 ;36 Suppl 1():40-50.

 

Obsessive-compulsive personality disorder (OCPD) is an early-onset disorder characterized by perfectionism, need for control, and cognitive rigidity. Its nosological status is currently under review. Historically, OCPD has been conceptualized as bearing a close relationship with obsessive-compulsive ...

Last Updated: 12 Nov 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Obsessive Compulsive Disorder" returned 87 free, full-text review articles on human participants. First 3 results:

Obsessive-compulsive disorder in children and adolescents.
 

Author(s): Georgina Krebs, Isobel Heyman

Journal: Arch. Dis. Child.. 2015 May;100(5):495-9.

 

Obsessive-compulsive disorder (OCD) in childhood and adolescence is an impairing condition, associated with a specific set of distressing symptoms incorporating repetitive, intrusive thoughts (obsessions) and distressing, time-consuming rituals (compulsions). This review considers ...

Last Updated: 18 Apr 2015

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Goal-directed learning and obsessive-compulsive disorder.
 

Author(s): Claire M Gillan, Trevor W Robbins

Journal: Philos. Trans. R. Soc. Lond., B, Biol. Sci.. 2014 Nov;369(1655):.

 

Obsessive-compulsive disorder (OCD) has become a paradigmatic case of goal-directed dysfunction in psychiatry. In this article, we review the neurobiological evidence, historical and recent, that originally led to this supposition and continues to support a habit hypothesis of OCD. ...

Last Updated: 30 Sep 2014

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Patient-reported outcomes in obsessive-compulsive disorder.
 

Author(s): Mythily Subramaniam, Pauline Soh, Clarissa Ong, Lee Seng Esmond Seow, Louisa Picco, Janhavi Ajit Vaingankar, Siow Ann Chong

Journal: Dialogues Clin Neurosci. 2014 Jun;16(2):239-54.

 

The purpose of the article was to provide an overview of patient-reported outcomes (PROs) and related measures that have been examined in the context of obsessive-compulsive disorder (OCD). The current review focused on patient-reported outcome measures (PROMs) that evaluated three ...

Last Updated: 25 Aug 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 4 Mar 2013

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Pharmacogenetic Study of Obsessive-Compulsive Disorder
 

Status: Recruiting

Condition Summary: Obsessive-Compulsive Disorder

 

Last Updated: 27 Apr 2015

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Attention Training for Childhood Obsessive Compulsive Disorder
 

Status: Recruiting

Condition Summary: Obsessive Compulsive Disorder

 

Last Updated: 31 May 2015

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