Antitrypsin Deficiency

Common Name(s)

Antitrypsin Deficiency

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Antitrypsin Deficiency" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Antitrypsin Deficiency" returned 280 free, full-text research articles on human participants. First 3 results:

Alpha1-antitrypsin deficiency - diagnostic testing and disease awareness in Germany and Italy.
 

Author(s): Timm Greulich, Stefania Ottaviani, Robert Bals, Philipp M Lepper, Claus Vogelmeier, Maurizio Luisetti, Ilaria Ferrarotti

Journal: Respir Med. 2013 Sep;107(9):1400-8.

 

Alpha1-antitrypsin (AAT) deficiency, although largely under-diagnosed, is the underlying cause of approximately 1% of COPD cases. Lack of awareness leads to long delays in diagnostic testing. Subsequently, lifestyle and treatment choices with potentially positive effects on prognosis ...

Last Updated: 26 Aug 2013

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Differences in adjustment between individuals with alpha-1 antitrypsin deficiency (AATD)-associated COPD and non-AATD COPD.
 

Author(s): Kristen E Holm, Soo Borson, Robert A Sandhaus, Dee W Ford, Charlie Strange, Russell P Bowler, Barry J Make, Frederick S Wamboldt

Journal: COPD. 2013 Apr;10(2):226-34.

 

Smokers who have severe alpha-1 antitrypsin deficiency (AATD) are at risk for developing COPD earlier in life than smokers without AATD, and are likely to experience challenges adjusting to their illness because they are in a highly productive life stage when they are diagnosed with ...

Last Updated: 3 Apr 2013

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[Post-infectious bronchiolitis obliterans in children with alpha-1 antitrypsin deficiency].
 

Author(s): K Oliveira, J Cardoso, T Torres, I Carvalho

Journal: An Pediatr (Barc). 2013 Aug;79(2):130-2.

 

Last Updated: 26 Jul 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Antitrypsin Deficiency" returned 51 free, full-text review articles on human participants. First 3 results:

Distinguishing alpha1-antitrypsin deficiency from asthma.
 

Author(s): Dareen Siri, Humam Farah, D Kyle Hogarth

Journal: Ann. Allergy Asthma Immunol.. 2013 Dec;111(6):458-64.

 

To explore the relations that exist between α1-antitrypsin deficiency (AATD) and asthma and to evaluate practices for screening patients with asthma for this genetically determined condition in the context of current guidelines.

Last Updated: 25 Nov 2013

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The parallel lives of alpha1-antitrypsin deficiency and pulmonary alveolar proteinosis.
 

Author(s): Bruce C Trapnell, Maurizio Luisetti

Journal:

 

In 1963, five cases of alpha1-antitrypsin deficiency were reported in the scientific literature, as well as an attempt to treat pulmonary alveolar proteinosis by a massive washing of the lung (whole lung lavage). Now, fifty years later, it seems the ideal moment not only to commemorate ...

Last Updated: 15 Nov 2013

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Augmentation therapy for alpha-1 antitrypsin deficiency: towards a personalised approach.
 

Author(s): Robert A Stockley, Marc Miravitlles, Claus Vogelmeier,

Journal:

 

Intravenous augmentation therapy is the only specific treatment available for emphysema associated with alpha-1 antitrypsin deficiency. Despite large observational studies and limited interventional studies there remains controversy about the efficacy of this treatment due to the ...

Last Updated: 15 Nov 2013

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Carbamazepine in Severe Liver Disease Due to Alpha-1 Antitrypsin Deficiency
 

Status: Recruiting

Condition Summary: Alpha-1-antitrypsin Deficiency; Liver Cirrhosis

 

Last Updated: 25 Feb 2013

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Safety Study of Gene Transfer Vector to Treat alpha1-antitrypsin Deficiency
 

Status: Not yet recruiting

Condition Summary: alpha1-antitrypsin Deficiency

 

Last Updated: 17 Jun 2014

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Endoscopic Lung Volume Reduction in Patients With Advanced Emphysema Due to alpha1 Antitrypsin Deficiency
 

Status: Recruiting

Condition Summary: Hereditary Emphysema (Alpha 1-antitrypsin Deficiency)

 

Last Updated: 19 May 2011

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