Non-Polyposis Colorectal Cancer

Common Name(s)

Non-Polyposis Colorectal Cancer, Cancer, Non-Polyposis Colorectal

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Non-Polyposis Colorectal Cancer" for support, advocacy or research.

Center for Jewish Genetics

The Center is dedicated to gathering and disseminating knowledge about Jewish genetic disorders and hereditary cancers. Its mission is to educate and serve health care professionals, clergy and the Jewish community.

Last Updated: 26 Dec 2012

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Stupid Cancer

Founded by and for young adult survivors, the I'm Too Young For This! Cancer Foundation (i[2]y), is the nation's leading grassroots advocate for the next generation of cancer survivors and their caregivers in their late teens, 20s and 30s. A TIME Magazine Best 50 Website, we have helped bring the cause of 'young adult cancer' to the national spotlight and rallied a brand new generation of activists to give voice to our forgotten population. Our mission is to empower young adults affected by cancer.

Last Updated: 6 Nov 2012

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Non-Polyposis Colorectal Cancer" for support, advocacy or research.

Center for Jewish Genetics

The Center is dedicated to gathering and disseminating knowledge about Jewish genetic disorders and hereditary cancers. Its mission is to educate and serve health care professionals, clergy and the Jewish community.

http://www.jewishgenetics.org

Last Updated: 26 Dec 2012

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Stupid Cancer

Founded by and for young adult survivors, the I'm Too Young For This! Cancer Foundation (i[2]y), is the nation's leading grassroots advocate for the next generation of cancer survivors and their caregivers in their late teens, 20s and 30s. A TIME Magazine Best 50 Website, we have helped bring the cause of 'young adult cancer' to the national spotlight and rallied a brand new generation of activists to give voice to our forgotten population. Our mission is to empower young adults affected by cancer.

http://stupidcancer.org

Last Updated: 6 Nov 2012

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Non-Polyposis Colorectal Cancer" returned 71 free, full-text research articles on human participants. First 3 results:

Longer telomeres are associated with cancer risk in MMR-proficient hereditary non-polyposis colorectal cancer.
 

Author(s): Nuria Seguí, Elisabet Guinó, Marta Pineda, Matilde Navarro, Fernando Bellido, Conxi Lázaro, Ignacio Blanco, Victor Moreno, Gabriel Capellá, Laura Valle

Journal:

 

Aberrant telomere length measured in blood has been associated with increased risk of several cancer types. In the field of hereditary non-polyposis colorectal cancer (CRC), and more particularly in Lynch syndrome, caused by germline mutations in the mismatch repair (MMR) genes, we ...

Last Updated: 5 Feb 2014

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Detection of DNA mismatch repair proteins in fresh human blood lymphocytes--towards a novel method for hereditary non-polyposis colorectal cancer (Lynch syndrome) screening.
 

Author(s): Samar Hassen, Bruce M Boman, Nawab Ali, Marcie Parker, Chandra Somerman, Zohra J Ali-Khan Catts, Akhtar A Ali, Jeremy Z Fields

Journal:

 

A broad population-based assay to detect individuals with Lynch Syndrome (LS) before they develop cancer would save lives and healthcare dollars via cancer prevention. LS is caused by a germline mutation in a DNA mismatch repair (MMR) gene, especially protein truncation-causing mutations ...

Last Updated: 17 Nov 2011

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Pulmonary sclerosing hemangioma in a 21-year-old male with metastatic hereditary non-polyposis colorectal cancer: report of a case.
 

Author(s): Tobias S Schiergens, Philipe N Khalil, Doris Mayr, Wolfgang E Thasler, Martin K Angele, Rudolf A Hatz, Karl-Walter Jauch, Axel Kleespies

Journal:

 

Pulmonary sclerosing hemangioma (SH) is a rare tumor of the lung predominantly affecting Asian women in their fifth decade of life. SH is thought to evolve from primitive respiratory epithelium and mostly shows benign biological behavior; however, cases of lymph node metastases, local ...

Last Updated: 20 Jun 2011

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Non-Polyposis Colorectal Cancer" returned 7 free, full-text review articles on human participants. First 3 results:

Molecular biology and clinical features of hereditary non-polyposis colorectal cancer.
 

Author(s): Sha-sha Guan, Guang-hai Dai

Journal: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2012 Jun;34(3):293-7.

 

Hereditary non-polyposis colorectal cancer (HNPCC) is an autosomal dominantly inherited disease associated with germ-line mutations in mismatch repair genes and microsatellite instability. This article reviews the molecular biology and clinical pathology of HNPCC.

Last Updated: 10 Jul 2012

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Hereditary Non-Polyposis Colorectal Cancer: the rise and fall of a confusing term.
 

Author(s): Jeremy R Jass

Journal: World J. Gastroenterol.. 2006 Aug;12(31):4943-50.

 

The term Hereditary Non-Polyposis Colorectal Cancer (HNPCC) is a poor descriptor of the syndrome described by Lynch. Over the last decade, the term has been applied to heterogeneous groups of families meeting limited clinical criteria, for example the Amsterdam criteria. It is now ...

Last Updated: 28 Aug 2006

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Diagnostic application of hMLH1 methylation in hereditary non-polyposis colorectal cancer.
 

Author(s): Nagahide Matsubara

Journal: Dis. Markers. 2004 ;20(4-5):277-82.

 

Colorectal cancer (CRC) due to mismatch repair (MMR) defect has distinct characteristics among unselected CRCs. These CRCs are biologically less aggressive and, thus, showing better prognosis but less sensitive to the 5FU-based chemotherapy. CRCs with MMR defect derive from both hereditary ...

Last Updated: 5 Nov 2004

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Hereditary Nonpolyposis Colorectal Cancer in Taiwan-Related Genetic Study and Clinical Applications
 

Status: Recruiting

Condition Summary: Hereditary Nonpolyposis Colorectal Cancer

 

Last Updated: 12 Aug 2009

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Women Who Are At Risk Or May Have Lynch Syndrome
 

Status: Recruiting

Condition Summary: Hereditary Nonpolyposis Colorectal Cancer; Lynch Syndrome

 

Last Updated: 13 Nov 2014

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Collecting Information From Patients and Family Members With Hereditary Colorectal Cancer Syndromes or Who Are at High Risk of Developing Colorectal Cancer
 

Status: Recruiting

Condition Summary: Colorectal Cancer; Hereditary Nonpolyposis Colorectal Cancer; Precancerous Condition

 

Last Updated: 1 Apr 2011

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