Non-Polyposis Colorectal Cancer

Common Name(s)

Non-Polyposis Colorectal Cancer, Cancer, Non-Polyposis Colorectal

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Non-Polyposis Colorectal Cancer" for support, advocacy or research.

Center for Jewish Genetics

The Center is dedicated to gathering and disseminating knowledge about Jewish genetic disorders and hereditary cancers. Its mission is to educate and serve health care professionals, clergy and the Jewish community.

Last Updated: 26 Dec 2012

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Stupid Cancer

Founded by and for young adult survivors, the I'm Too Young For This! Cancer Foundation (i[2]y), is the nation's leading grassroots advocate for the next generation of cancer survivors and their caregivers in their late teens, 20s and 30s. A TIME Magazine Best 50 Website, we have helped bring the cause of 'young adult cancer' to the national spotlight and rallied a brand new generation of activists to give voice to our forgotten population. Our mission is to empower young adults affected by cancer.

Last Updated: 6 Nov 2012

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Non-Polyposis Colorectal Cancer" for support, advocacy or research.

Center for Jewish Genetics

The Center is dedicated to gathering and disseminating knowledge about Jewish genetic disorders and hereditary cancers. Its mission is to educate and serve health care professionals, clergy and the Jewish community.

http://www.jewishgenetics.org

Last Updated: 26 Dec 2012

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Stupid Cancer

Founded by and for young adult survivors, the I'm Too Young For This! Cancer Foundation (i[2]y), is the nation's leading grassroots advocate for the next generation of cancer survivors and their caregivers in their late teens, 20s and 30s. A TIME Magazine Best 50 Website, we have helped bring the cause of 'young adult cancer' to the national spotlight and rallied a brand new generation of activists to give voice to our forgotten population. Our mission is to empower young adults affected by cancer.

http://stupidcancer.org

Last Updated: 6 Nov 2012

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Non-Polyposis Colorectal Cancer" returned 89 free, full-text research articles on human participants. First 3 results:

Intraductal papillary mucinous neoplasm of the ileal heterotopic pancreas in a patient with hereditary non-polyposis colorectal cancer: A case report.
 

Author(s): Sang Hwa Lee, Wook Youn Kim, Dae-Yong Hwang, Hye Seung Han

Journal: World J. Gastroenterol.. 2015 Jul;21(25):7916-20.

 

We report a case of intraductal papillary mucinous neoplasm (IPMN) originating from the ileal heterotopic pancreas in a patient with hereditary non-polyposis colorectal cancer (HNPCC). A 49-year-old woman had a past history of total colectomy and total hysterectomy with bilateral ...

Last Updated: 13 Jul 2015

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Longer telomeres are associated with cancer risk in MMR-proficient hereditary non-polyposis colorectal cancer.
 

Author(s): Nuria Seguí, Elisabet Guinó, Marta Pineda, Matilde Navarro, Fernando Bellido, Conxi Lázaro, Ignacio Blanco, Victor Moreno, Gabriel Capellá, Laura Valle

Journal:

 

Aberrant telomere length measured in blood has been associated with increased risk of several cancer types. In the field of hereditary non-polyposis colorectal cancer (CRC), and more particularly in Lynch syndrome, caused by germline mutations in the mismatch repair (MMR) genes, we ...

Last Updated: 5 Feb 2014

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Detection of DNA mismatch repair proteins in fresh human blood lymphocytes--towards a novel method for hereditary non-polyposis colorectal cancer (Lynch syndrome) screening.
 

Author(s): Samar Hassen, Bruce M Boman, Nawab Ali, Marcie Parker, Chandra Somerman, Zohra J Ali-Khan Catts, Akhtar A Ali, Jeremy Z Fields

Journal:

 

A broad population-based assay to detect individuals with Lynch Syndrome (LS) before they develop cancer would save lives and healthcare dollars via cancer prevention. LS is caused by a germline mutation in a DNA mismatch repair (MMR) gene, especially protein truncation-causing mutations ...

Last Updated: 17 Nov 2011

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Non-Polyposis Colorectal Cancer" returned 11 free, full-text review articles on human participants. First 3 results:

Molecular biology and clinical features of hereditary non-polyposis colorectal cancer.
 

Author(s): Sha-sha Guan, Guang-hai Dai

Journal: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2012 Jun;34(3):293-7.

 

Hereditary non-polyposis colorectal cancer (HNPCC) is an autosomal dominantly inherited disease associated with germ-line mutations in mismatch repair genes and microsatellite instability. This article reviews the molecular biology and clinical pathology of HNPCC.

Last Updated: 10 Jul 2012

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[HNPCC (hereditary non-polyposis colorectal cancer) or Lynch syndrome: a syndrome related to a failure of DNA repair system].
 

Author(s): Gilles Manceau, Mehdi Karoui, Antoine Charachon, Jean-Charles Delchier, Iradj Sobhani

Journal: Bull Cancer. 2011 Mar;98(3):323-36.

 

The HNPCC syndrome (hereditary non polyposis colon cancer) or Lynch syndrome stands for an autosomic dominant condition leading to the most prevalent hereditary colo-rectal cancers (CCR). MMR (mismatch repair)'s genes are involved in carcinogenesis as they play a role in ADNA mismatch ...

Last Updated: 18 Apr 2011

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Review article: Detection and management of hereditary non-polyposis colorectal cancer (Lynch syndrome).
 

Author(s): D Ramsoekh, M E Van Leerdam, A Wagner, E J Kuipers

Journal: Aliment. Pharmacol. Ther.. 2007 Dec;26 Suppl 2():101-11.

 

The most common hereditary colorectal cancer syndrome is hereditary non-polyposis colorectal cancer (HNPCC), also known as Lynch syndrome. Diagnosis of this syndrome is difficult, because of lack of specific diagnostic features.

Last Updated: 17 Dec 2007

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Registry for Women Who Are At Risk Or May Have Lynch Syndrome
 

Status: Recruiting

Condition Summary: Hereditary Nonpolyposis Colorectal Cancer; Lynch Syndrome

 

Last Updated: 15 Nov 2016

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Mesalamine for Colorectal Cancer Prevention Program in Lynch Syndrome
 

Status: Not yet recruiting

Condition Summary: Colorectal Neoplasms, Hereditary Nonpolyposis

 

Last Updated: 9 Aug 2016

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Ileal Pouch-Anal Anastomosis Registry
 

Status: Recruiting

Condition Summary: Ileal Pouch-Anal Anastomosis

 

Last Updated: 28 Mar 2016

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