Antiphospholipid Syndrome

Common Name(s)

Antiphospholipid Syndrome, Antiphospholipid Antibody Syndrome

Antiphospholipid syndrome is an autoimmune disorder. It is characterized by high levels of multiple different antibodies that are associated with clots in the arteries and veins. Symptoms vary and can include blood clots, miscarriage, rash, chronic headaches, dementia, and seizures. Treatment involves thinning the blood to reduce clotting.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Antiphospholipid Syndrome" for support, advocacy or research.

APS Foundation of America, Inc.

The APS Foundation of America, Inc. is dedicated to fostering and facilitating joint efforts in the areas of education, public awareness, research and patient services in an effective and ethical manner.

Last Updated: 12 Aug 2013

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International Scleroderma Network

Our mission is to provide stellar worldwide research, support, education and awareness for scleroderma and related illnesses.

Last Updated: 18 Apr 2010

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General Support Organizations

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How do you compare to others with this condition?

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Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Antiphospholipid Syndrome" for support, advocacy or research.

APS Foundation of America, Inc.

The APS Foundation of America, Inc. is dedicated to fostering and facilitating joint efforts in the areas of education, public awareness, research and patient services in an effective and ethical manner.

http://www.apsfa.org

Last Updated: 12 Aug 2013

View Details
International Scleroderma Network

Our mission is to provide stellar worldwide research, support, education and awareness for scleroderma and related illnesses.

http://www.sclero.org/

Last Updated: 18 Apr 2010

View Details

 

General Support Organizations

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General Resources

Antiphospholipid Antibody Syndrome

This pamphlet is a layman’s terms summary of Antiphospholipid Syndrome (APS). It covers such topics as diagnosis, symptoms, treatment, and coping. It is meant for patients newly diagnosed, however would also be good for informing friends and family

Updated 13 Nov 2012

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Antiphospholipid Antibody Syndrome (APS) & Pregnancy

Antiphospholipid antibody syndrome (APS) is an illness that involve the immune system, and causes increased clotting of the blood. Normally antibodies, chemicals made by the immune system, are helpful in fighting germs or viral infections from outsid

Updated 13 Nov 2012

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APS Foundation of America, Inc Fan Page

The APS Foundation of America, Inc. is the leading United States nonprofit health agency dedicated to bringing national awareness to Antiphospholipid Antibody Syndrome (APS).

Updated 13 Nov 2012

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Blogs

APS Friends & Support Forum

Are you looking for Support for Antiphospholipid Antibody Syndrome, APS, APLS, APLA, Hughes Syndrome, or Sticky Blood? Well you've come to the right place! This is an private forum for people who have Antiphospholipid Antibody Syndrome, friends, fam

Updated 13 Nov 2012

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Antiphospholipid Syndrome" returned 682 free, full-text research articles on human participants. First 3 results:

Thrombosis and antiphospholipid antibody syndrome during acute Q fever: A cross-sectional study.
 

Author(s): Matthieu Million, Nathalie Bardin, Simon Bessis, Nadia Nouiakh, Charlaine Douliery, Sophie Edouard, Emmanouil Angelakis, Annick Bosseray, Olivier Epaulard, Stéphanie Branger, Bernard Chaudier, Karine Blanc-Laserre, Nicole Ferreira-Maldent, Elisa Demonchy, France Roblot, Jacques Reynes, Felix Djossou, Camelia Protopopescu, Patrizia Carrieri, Laurence Camoin-Jau, Jean-Louis Mege, Didier Raoult

Journal: Medicine (Baltimore). 2017 Jul;96(29):e7578.

 

Q fever is a neglected and potentially fatal disease. During acute Q fever, antiphospholipid antibodies are very prevalent and have been associated with fever, thrombocytopenia, acquired heart valve disease, and progression to chronic endocarditis. However, thrombosis, the main clinical ...

Last Updated: 20 Jul 2017

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Effect on mother and child of eculizumab given before caesarean section in a patient with severe antiphospholipid syndrome: A case report.
 

Author(s): Alice Gustavsen, Lillemor Skattum, Grethe Bergseth, Bjorg Lorentzen, Yngvar Floisand, Vidar Bosnes, Tom Eirik Mollnes, Andreas Barratt-Due

Journal: Medicine (Baltimore). 2017 Mar;96(11):e6338.

 

Antiphospholipid syndrome (APS) in pregnancy may trigger the life-threatening catastrophic antiphospholipid syndrome (CAPS). Complement activation is implicated in the pathogenesis, and inhibition of complement factor C5 is suggested as an additional treatment option.

Last Updated: 15 Mar 2017

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Antiphospholipid Antibody Titers and Clinical Outcomes in Patients with Recurrent Miscarriage and Antiphospholipid Antibody Syndrome: A Prospective Study.
 

Author(s): Yu Song, Hai-Yan Wang, Jie Qiao, Ping Liu, Hong-Bin Chi

Journal: Chin. Med. J.. 2017 02;130(3):267-272.

 

The management of patients with recurrent miscarriage (RM) and antiphospholipid antibody syndrome (APS) includes prolonged treatment with heparin and aspirin, starting from the confirmation of pregnancy and continuing until 6 weeks after birth. This study was conducted to determine ...

Last Updated: 31 Jan 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Antiphospholipid Syndrome" returned 141 free, full-text review articles on human participants. First 3 results:

Gene expression in obstetric antiphospholipid syndrome: a systematic review.
 

Author(s): M Muhammad Aliff, S Muhammad Shazwan, M M Nur Fariha, A R Hayati, A R Nur Syahrina, M Maizatul Azma, A H Nazefah, S Jameela, A A Asral Wirda

Journal: Malays J Pathol. 2016 Dec;38(3):285-294.

 

Antiphospholipid syndrome (APS) is a multisystem disease that may present as venous or arterial thrombosis and/or pregnancy complications with the presence of antiphospholipid antibodies. Until today, heterogeneity of pathogenic mechanism fits well with various clinical manifestations. ...

Last Updated: 28 Dec 2016

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MicroRNA expression in antiphospholipid syndrome: a systematic review and microRNA target genes analysis.
 

Author(s): S Muhammad Shazwan, M Muhammad Aliff, A A Asral Wirda, A R Hayati, M Maizatul Azma, A R Nur Syahrina, A H Nazefah, S Jameela, M M Nur Fariha

Journal: Malays J Pathol. 2016 Dec;38(3):273-283.

 

Antiphospholipid antibodies (aPL) are autoantibodies that attack phospholipid through anti-beta 2-glycoprotein 1. The actions of aPL are associated with events leading to thrombosis and morbidity in pregnancy. Antiphospholipid syndrome (APS) is diagnosed when a patient is persistently ...

Last Updated: 28 Dec 2016

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The Role of TLR4 on B Cell Activation and Anti-β2GPI Antibody Production in the Antiphospholipid Syndrome.
 

Author(s): Si Cheng, Haibo Wang, Hong Zhou

Journal: J Immunol Res. 2016 ;2016():1719720.

 

High titer of anti-β2-glycoprotein I antibodies (anti-β2GPI Ab) plays a pathogenic role in antiphospholipid syndrome (APS). Numerous studies have focused on the pathological mechanism in APS; however, little attention is paid to the immune mechanism of production of anti-β2GPI ...

Last Updated: 21 Nov 2016

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 24 May 2017

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Rivaroxaban in Thrombotic Antiphospholipid Syndrome
 

Status: Recruiting

Condition Summary: Antiphospholipid Syndrome

 

Last Updated: 2 May 2017

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Genetic Risk Factors Associated With Antiphospholipid Antibody Syndrome
 

Status: Recruiting

Condition Summary: Antiphospholipid Syndrome

 

Last Updated: 18 May 2017

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