Antiphospholipid Syndrome

Common Name(s)

Antiphospholipid Syndrome, Antiphospholipid Antibody Syndrome

Antiphospholipid syndrome is an autoimmune disorder. It is characterized by high levels of multiple different antibodies that are associated with clots in the arteries and veins. Symptoms vary and can include blood clots, miscarriage, rash, chronic headaches, dementia, and seizures. Treatment involves thinning the blood to reduce clotting.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Antiphospholipid Syndrome" for support, advocacy or research.

APS Foundation of America, Inc.

The APS Foundation of America, Inc. is dedicated to fostering and facilitating joint efforts in the areas of education, public awareness, research and patient services in an effective and ethical manner.

Last Updated: 12 Aug 2013

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International Scleroderma Network

Our mission is to provide stellar worldwide research, support, education and awareness for scleroderma and related illnesses.

Last Updated: 18 Apr 2010

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General Support Organizations

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How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Antiphospholipid Syndrome" for support, advocacy or research.

APS Foundation of America, Inc.

The APS Foundation of America, Inc. is dedicated to fostering and facilitating joint efforts in the areas of education, public awareness, research and patient services in an effective and ethical manner.

http://www.apsfa.org

Last Updated: 12 Aug 2013

View Details
International Scleroderma Network

Our mission is to provide stellar worldwide research, support, education and awareness for scleroderma and related illnesses.

http://www.sclero.org/

Last Updated: 18 Apr 2010

View Details

 

General Support Organizations

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General Resources

Antiphospholipid Antibody Syndrome

This pamphlet is a layman’s terms summary of Antiphospholipid Syndrome (APS). It covers such topics as diagnosis, symptoms, treatment, and coping. It is meant for patients newly diagnosed, however would also be good for informing friends and family

Updated 13 Nov 2012

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Antiphospholipid Antibody Syndrome (APS) & Pregnancy

Antiphospholipid antibody syndrome (APS) is an illness that involve the immune system, and causes increased clotting of the blood. Normally antibodies, chemicals made by the immune system, are helpful in fighting germs or viral infections from outsid

Updated 13 Nov 2012

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APS Foundation of America, Inc Fan Page

The APS Foundation of America, Inc. is the leading United States nonprofit health agency dedicated to bringing national awareness to Antiphospholipid Antibody Syndrome (APS).

Updated 13 Nov 2012

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Blogs

APS Friends & Support Forum

Are you looking for Support for Antiphospholipid Antibody Syndrome, APS, APLS, APLA, Hughes Syndrome, or Sticky Blood? Well you've come to the right place! This is an private forum for people who have Antiphospholipid Antibody Syndrome, friends, fam

Updated 13 Nov 2012

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Antiphospholipid Syndrome" returned 701 free, full-text research articles on human participants. First 3 results:

Oxidation of β2-glycoprotein I associates with IgG antibodies to domain I in patients with antiphospholipid syndrome.
 

Author(s): Maria Gabriella Raimondo, Charis Pericleous, Anna Radziszewska, Maria Orietta Borghi, Silvia Pierangeli, Pier Luigi Meroni, Ian Giles, Anisur Rahman, Yiannis Ioannou

Journal:

 

Domain I (DI) of beta-2-glycoprotein I (β2GPI) contains the immunodominant epitope for pathogenic antiphospholipid antibodies (aPL). DI is exposed in the linear form of the molecule but not in the circular form that comprises 90% of serum β2GPI. The majority of circulating β2GPI ...

Last Updated: 31 Dec 1969

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Primary thrombosis of the anterior descending in a patient with antiphospholipid antibody syndrome
 

Author(s): Jorge Acuña-Valerio, Marco Antonio Peña-Duque, Álvaro Contreras-Villaseñor

Journal: Gac Med Mex. 2017 ;153(4):526-530.

 

Antiphospholipid antibody syndrome is a heterogeneous clinical and biochemical entity. We present the case of a young male with history of venous thromboembolism. This time he presents because of chest ischemic pain associated with ST segment elevation. He was taken to the cath lab ...

Last Updated: 31 Dec 1969

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Thrombosis and antiphospholipid antibody syndrome during acute Q fever: A cross-sectional study.
 

Author(s): Matthieu Million, Nathalie Bardin, Simon Bessis, Nadia Nouiakh, Charlaine Douliery, Sophie Edouard, Emmanouil Angelakis, Annick Bosseray, Olivier Epaulard, Stéphanie Branger, Bernard Chaudier, Karine Blanc-Laserre, Nicole Ferreira-Maldent, Elisa Demonchy, France Roblot, Jacques Reynes, Felix Djossou, Camelia Protopopescu, Patrizia Carrieri, Laurence Camoin-Jau, Jean-Louis Mege, Didier Raoult

Journal: Medicine (Baltimore). 2017 Jul;96(29):e7578.

 

Q fever is a neglected and potentially fatal disease. During acute Q fever, antiphospholipid antibodies are very prevalent and have been associated with fever, thrombocytopenia, acquired heart valve disease, and progression to chronic endocarditis. However, thrombosis, the main clinical ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Antiphospholipid Syndrome" returned 151 free, full-text review articles on human participants. First 3 results:

Update on antiphospholipid antibody syndrome.
 

Author(s): Michelle Remião Ugolini Lopes, Adriana Danowski, Andreas Funke, Jozelia Rêgo, Roger Levy, Danieli Castro Oliveira de Andrade

Journal: Rev Assoc Med Bras (1992). 2017 Nov;63(11):994-999.

 

Antiphospholipid syndrome (APS) is an autoimmune disease characterized by antiphospholipid antibodies (aPL) associated with thrombosis and/or pregnancy morbidity. Most APS events are directly related to thrombotic events, which may affect small, medium or large vessels. Other clinical ...

Last Updated: 31 Dec 1969

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[The scoring system for the risk-stratification in patients with the antiphospholipid syndrome].
 

Author(s): Kenji Oku

Journal: Nihon Rinsho Meneki Gakkai Kaishi. 2017 ;40(6):435-441.

 

  Antiphospholipid syndrome (APS) is a clinical disorder characterized by thrombosis and/or pregnancy morbidity in the persistence of the pathogenic autoantibodies, the antiphospholipid antibodies (aPL). Recurernt thrombosis is often observed in patients with APS which requires ...

Last Updated: 31 Dec 1969

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Catastrophic antiphospholipid syndrome. Case report and literature review
 

Author(s): Luis del Carpio-Orantes, Chantall Citlally Martínez-Anaya, Elías Bonilla-Casas

Journal: Gac Med Mex. 2017 ;153(4):531-536.

 

The present document is the report of a case of a very rare clinical entity, which presents with acute multiorganic failure after a thrombotic storm related to antiphospholipid antibodies, the so-called catastrophic antiphospholipid syndrome, which began as a recurrent picture of ...

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Ocular Findings in Women With Primary Antiphospholipid Syndrome
 

Status: Recruiting

Condition Summary: Primary Antiphospholipid Syndrome

 

Last Updated: 7 Mar 2018

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Last Updated: 1 Mar 2018

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Multi-organ Screening for Asymptomatic Ischaemia in Antiphospholipid Syndrome
 

Status: Not yet recruiting

Condition Summary: Antiphospholipid Syndrome

 

Last Updated: 16 Nov 2017

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