Antiphospholipid Syndrome

Common Name(s)

Antiphospholipid Syndrome, Antiphospholipid Antibody Syndrome

Antiphospholipid syndrome is an autoimmune disorder. It is characterized by high levels of multiple different antibodies that are associated with clots in the arteries and veins. Symptoms vary and can include blood clots, miscarriage, rash, chronic headaches, dementia, and seizures. Treatment involves thinning the blood to reduce clotting.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Antiphospholipid Syndrome" for support, advocacy or research.

APS Foundation of America, Inc.

The APS Foundation of America, Inc. is dedicated to fostering and facilitating joint efforts in the areas of education, public awareness, research and patient services in an effective and ethical manner.

Last Updated: 12 Aug 2013

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International Scleroderma Network

Our mission is to provide stellar worldwide research, support, education and awareness for scleroderma and related illnesses.

Last Updated: 18 Apr 2010

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Antiphospholipid Syndrome" for support, advocacy or research.

APS Foundation of America, Inc.

The APS Foundation of America, Inc. is dedicated to fostering and facilitating joint efforts in the areas of education, public awareness, research and patient services in an effective and ethical manner.

http://www.apsfa.org

Last Updated: 12 Aug 2013

View Details
International Scleroderma Network

Our mission is to provide stellar worldwide research, support, education and awareness for scleroderma and related illnesses.

http://www.sclero.org/

Last Updated: 18 Apr 2010

View Details

 

General Support Organizations

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General Resources

Antiphospholipid Antibody Syndrome

This pamphlet is a layman’s terms summary of Antiphospholipid Syndrome (APS). It covers such topics as diagnosis, symptoms, treatment, and coping. It is meant for patients newly diagnosed, however would also be good for informing friends and family

Updated 13 Nov 2012

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Antiphospholipid Antibody Syndrome (APS) & Pregnancy

Antiphospholipid antibody syndrome (APS) is an illness that involve the immune system, and causes increased clotting of the blood. Normally antibodies, chemicals made by the immune system, are helpful in fighting germs or viral infections from outsid

Updated 13 Nov 2012

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APS Foundation of America, Inc Fan Page

The APS Foundation of America, Inc. is the leading United States nonprofit health agency dedicated to bringing national awareness to Antiphospholipid Antibody Syndrome (APS).

Updated 13 Nov 2012

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Blogs

APS Friends & Support Forum

Are you looking for Support for Antiphospholipid Antibody Syndrome, APS, APLS, APLA, Hughes Syndrome, or Sticky Blood? Well you've come to the right place! This is an private forum for people who have Antiphospholipid Antibody Syndrome, friends, fam

Updated 13 Nov 2012

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Antiphospholipid Syndrome" returned 672 free, full-text research articles on human participants. First 3 results:

Effect on mother and child of eculizumab given before caesarean section in a patient with severe antiphospholipid syndrome: A case report.
 

Author(s): Alice Gustavsen, Lillemor Skattum, Grethe Bergseth, Bjorg Lorentzen, Yngvar Floisand, Vidar Bosnes, Tom Eirik Mollnes, Andreas Barratt-Due

Journal: Medicine (Baltimore). 2017 Mar;96(11):e6338.

 

Antiphospholipid syndrome (APS) in pregnancy may trigger the life-threatening catastrophic antiphospholipid syndrome (CAPS). Complement activation is implicated in the pathogenesis, and inhibition of complement factor C5 is suggested as an additional treatment option.

Last Updated: 15 Mar 2017

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Antiphospholipid Antibody Titers and Clinical Outcomes in Patients with Recurrent Miscarriage and Antiphospholipid Antibody Syndrome: A Prospective Study.
 

Author(s): Yu Song, Hai-Yan Wang, Jie Qiao, Ping Liu, Hong-Bin Chi

Journal: Chin. Med. J.. 2017 02;130(3):267-272.

 

The management of patients with recurrent miscarriage (RM) and antiphospholipid antibody syndrome (APS) includes prolonged treatment with heparin and aspirin, starting from the confirmation of pregnancy and continuing until 6 weeks after birth. This study was conducted to determine ...

Last Updated: 31 Jan 2017

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Fatal antiphospholipid syndrome following endoscopic transnasal-transsphenoidal surgery for a pituitary tumor: A case report.
 

Author(s): Chiao-Zhu Li, Chiao-Ching Li, Chih-Chuan Hsieh, Meng-Chi Lin, Dueng-Yuan Hueng, Feng-Chen Liu, Yuan-Hao Chen

Journal: Medicine (Baltimore). 2017 Jan;96(1):e5774.

 

The fatal type of antiphospholipid syndrome is a rare but life-threating condition. It may be triggered by surgery or infection. Endoscopic transnasal-transsphenoidal surgery is a common procedure for pituitary tumor. We report a catastrophic case of a young woman died of fatal antiphospholipid ...

Last Updated: 10 Jan 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Antiphospholipid Syndrome" returned 127 free, full-text review articles on human participants. First 3 results:

The Role of TLR4 on B Cell Activation and Anti-β2GPI Antibody Production in the Antiphospholipid Syndrome.
 

Author(s): Si Cheng, Haibo Wang, Hong Zhou

Journal: J Immunol Res. 2016 ;2016():1719720.

 

High titer of anti-β2-glycoprotein I antibodies (anti-β2GPI Ab) plays a pathogenic role in antiphospholipid syndrome (APS). Numerous studies have focused on the pathological mechanism in APS; however, little attention is paid to the immune mechanism of production of anti-β2GPI ...

Last Updated: 21 Nov 2016

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The Role of Complement Inhibition in Thrombotic Angiopathies and Antiphospholipid Syndrome.
 

Author(s): Doruk Erkan, Jane E Salmon

Journal: Turk J Haematol. 2016 Mar;33(1):1-7.

 

Antiphospholipid syndrome (APS) is characterized by thrombosis (arterial, venous, small vessel) and/or pregnancy morbidity occurring in patients with persistently positive antiphospholipid antibodies (aPL). Catastrophic APS is the most severe form of the disease, characterized by ...

Last Updated: 29 Mar 2016

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Impact of Antiphospholipid Syndrome and/or Systemic Lupus Erythematosus on the Long-term Adverse Cardiovascular Outcomes in Patients After Percutaneous Coronary Intervention: A Systematic Review and Meta-analysis.
 

Author(s): Pravesh Kumar Bundhun, Kamini Devi Boodhoo, Man-Yun Long, Meng-Hua Chen

Journal: Medicine (Baltimore). 2016 Mar;95(12):e3200.

 

Antiphospholipid syndrome (APS) and systemic lupus erythematosus (SLE) are 2 rare autoimmune disorders which commonly affect women. Several previous studies showed APS to have been evolved from SLE. Secondary APS often coexists with SLE. One common feature relating these 2 diseases ...

Last Updated: 26 Mar 2016

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 24 Oct 2016

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Rivaroxaban in Thrombotic Antiphospholipid Syndrome
 

Status: Recruiting

Condition Summary: Antiphospholipid Syndrome

 

Last Updated: 2 May 2017

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Genetic Risk Factors Associated With Antiphospholipid Antibody Syndrome
 

Status: Recruiting

Condition Summary: Antiphospholipid Syndrome

 

Last Updated: 18 May 2017

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