Neuromyelitis optica spectrum disorder

Common Name(s)

Neuromyelitis optica spectrum disorder

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Neuromyelitis optica spectrum disorder" for support, advocacy or research.

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The Guthy-Jackson Charitable Foundation

The Guthy-Jackson Charitable Foundation is dedicated to funding research in the search to understand the pathophysiology and biochemistry of NMO Spectrum Disease. Our Foundation is passionate in its support of providing opportunities to develop programs for prevention, clinical treatments, and an eventual cure for this rare and often misunderstood disease. We are committed to providing an online community for those who have been diagnosed with NMO, as well as providing centralized information resources for individuals who want to learn more about this rare disease.

Last Updated: 19 Feb 2013

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Neuromyelitis optica spectrum disorder" for support, advocacy or research.

Logo
The Guthy-Jackson Charitable Foundation

The Guthy-Jackson Charitable Foundation is dedicated to funding research in the search to understand the pathophysiology and biochemistry of NMO Spectrum Disease. Our Foundation is passionate in its support of providing opportunities to develop programs for prevention, clinical treatments, and an eventual cure for this rare and often misunderstood disease. We are committed to providing an online community for those who have been diagnosed with NMO, as well as providing centralized information resources for individuals who want to learn more about this rare disease.

http://www.guthyjacksonfoundation.org

Last Updated: 19 Feb 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Neuromyelitis optica spectrum disorder" returned 36 free, full-text research articles on human participants. First 3 results:

A case report of neuromyelitis optica spectrum disorder with peripheral neuropathy as the first episode.
 

Author(s): Lu-Mei Chi, Yu Gao, Guang-Xian Nan

Journal: Medicine (Baltimore). 2018 Mar;97(10):e0059.

 

Neuromyelitis optica spectrum disorders (NMOSDs) represent recurrent autoimmune diseases, generally beginning with optic nerve neuritis or acute transverse myelitis.

Last Updated: 31 Dec 1969

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Increased frequency of IL-6-producing non-classical monocytes in neuromyelitis optica spectrum disorder.
 

Author(s): Byung Soo Kong, Yeseul Kim, Ga Young Kim, Jae-Won Hyun, Su-Hyun Kim, Aeran Jeong, Ho Jin Kim

Journal:

 

Neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune inflammatory disease of the central nervous system that preferentially affects the optic nerves, spinal cord, and area postrema. A series of evidence suggested that B cells play a fundamental role in the pathogenesis ...

Last Updated: 31 Dec 1969

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Comparison of cognitive and brain grey matter volume profiles between multiple sclerosis and neuromyelitis optica spectrum disorder.
 

Author(s): Hiroki Masuda, Shigeki Hirano, Nobuyoshi Takahashi, Etsuko Hatsugano, Akiyuki Uzawa, Tomohiko Uchida, Ryohei Ohtani, Satoshi Kuwabara, Masahiro Mori

Journal:

 

Brain regions responsible for cognitive dysfunction in MS and neuromyelitis optica spectrum disorder (NMOSD) are not known. Our aim of this study was to investigate whether cognitive function and brain volume differed between MS and NMOSD in Japanese patients.

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Neuromyelitis optica spectrum disorder" returned 4 free, full-text review articles on human participants. First 3 results:

Optical Coherence Tomography and Magnetic Resonance Imaging in Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorder.
 

Author(s): Praveena Manogaran, James V M Hanson, Elisabeth D Olbert, Christine Egger, Carla Wicki, Christina Gerth-Kahlert, Klara Landau, Sven Schippling

Journal:

 

Irreversible disability in multiple sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD) is largely attributed to neuronal and axonal degeneration, which, along with inflammation, is one of the major pathological hallmarks of these diseases. Optical coherence tomography ...

Last Updated: 31 Dec 1969

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Use of Advanced Magnetic Resonance Imaging Techniques in Neuromyelitis Optica Spectrum Disorder.
 

Author(s): Stephane Kremer, Felix Renard, Sophie Achard, Marco A Lana-Peixoto, Jacqueline Palace, Nasrin Asgari, Eric C Klawiter, Silvia N Tenembaum, Brenda Banwell, Benjamin M Greenberg, Jeffrey L Bennett, Michael Levy, Pablo Villoslada, Albert Saiz, Kazuo Fujihara, Koon Ho Chan, Sven Schippling, Friedemann Paul, Ho Jin Kim, Jerome de Seze, Jens T Wuerfel, , Philippe Cabre, Romain Marignier, Thomas Tedder, Danielle van Pelt, Simon Broadley, Tanuja Chitnis, Dean Wingerchuk, Lekha Pandit, Maria Isabel Leite, Metha Apiwattanakul, Ingo Kleiter, Naraporn Prayoonwiwat, May Han, Kerstin Hellwig, Katja van Herle, Gareth John, D Craig Hooper, Ichiro Nakashima, Douglas Sato, Michael R Yeaman, Emmanuelle Waubant, Scott Zamvil, Olaf Stüve, Orhan Aktas, Terry J Smith, Anu Jacob, Kevin O'Connor

Journal: JAMA Neurol. 2015 Jul;72(7):815-22.

 

Brain parenchymal lesions are frequently observed on conventional magnetic resonance imaging (MRI) scans of patients with neuromyelitis optica (NMO) spectrum disorder, but the specific morphological and temporal patterns distinguishing them unequivocally from lesions caused by other ...

Last Updated: 31 Dec 1969

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MRI characteristics of neuromyelitis optica spectrum disorder: an international update.
 

Author(s): Ho Jin Kim, Friedemann Paul, Marco A Lana-Peixoto, Silvia Tenembaum, Nasrin Asgari, Jacqueline Palace, Eric C Klawiter, Douglas K Sato, Jérôme de Seze, Jens Wuerfel, Brenda L Banwell, Pablo Villoslada, Albert Saiz, Kazuo Fujihara, Su-Hyun Kim,

Journal: Neurology. 2015 Mar;84(11):1165-73.

 

Since its initial reports in the 19th century, neuromyelitis optica (NMO) had been thought to involve only the optic nerves and spinal cord. However, the discovery of highly specific anti-aquaporin-4 antibody diagnostic biomarker for NMO enabled recognition of more diverse clinical ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

A Phase III Study of TACI-antibody Fusion Protein Injection (RC18) in Subjects With Neuromyelitis Optica Spectrum Disorders
 

Status: Recruiting

Condition Summary: Neuromyelitis Optica Spectrum Disorders

 

Last Updated: 6 Nov 2017

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A Double-masked, Placebo-controlled Study With Open Label Period to Evaluate MEDI-551 in Neuromyelitis Optica and Neuromyelitis Optica Spectrum Disorders
 

Status: Recruiting

Condition Summary: Neuromyelitis Optica and Neuromyelitis Optica Spectrum Disorders

 

Last Updated: 13 Jun 2018

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Tocilizumab vs Azathioprine in Neuromyelitis Optica Spectrum Disorders
 

Status: Recruiting

Condition Summary: Neuromyelitis Optica Spectrum Disorders; Neuromyelitis Optica

 

Last Updated: 17 Nov 2017

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