Neuromyelitis optica spectrum disorder

Common Name(s)

Neuromyelitis optica spectrum disorder

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Neuromyelitis optica spectrum disorder" for support, advocacy or research.

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The Guthy-Jackson Charitable Foundation

The Guthy-Jackson Charitable Foundation is dedicated to funding research in the search to understand the pathophysiology and biochemistry of NMO Spectrum Disease. Our Foundation is passionate in its support of providing opportunities to develop programs for prevention, clinical treatments, and an eventual cure for this rare and often misunderstood disease. We are committed to providing an online community for those who have been diagnosed with NMO, as well as providing centralized information resources for individuals who want to learn more about this rare disease.

Last Updated: 19 Feb 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Neuromyelitis optica spectrum disorder" for support, advocacy or research.

Logo
The Guthy-Jackson Charitable Foundation

The Guthy-Jackson Charitable Foundation is dedicated to funding research in the search to understand the pathophysiology and biochemistry of NMO Spectrum Disease. Our Foundation is passionate in its support of providing opportunities to develop programs for prevention, clinical treatments, and an eventual cure for this rare and often misunderstood disease. We are committed to providing an online community for those who have been diagnosed with NMO, as well as providing centralized information resources for individuals who want to learn more about this rare disease.

http://www.guthyjacksonfoundation.org

Last Updated: 19 Feb 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Neuromyelitis optica spectrum disorder" returned 20 free, full-text research articles on human participants. First 3 results:

Next-generation sequencing identifies altered whole blood microRNAs in neuromyelitis optica spectrum disorder which may permit discrimination from multiple sclerosis.
 

Author(s): Andreas Keller, Petra Leidinger, Eckart Meese, Jan Haas, Christina Backes, Ludwig Rasche, Janina R Behrens, Catherina Pfuhl, Katharina Wakonig, René M Gieß, Sven Jarius, Benjamin Meder, Judith Bellmann-Strobl, Friedemann Paul, Florence C Pache, Klemens Ruprecht

Journal:

 

Neuromyelitis optica spectrum disorder (NMOSD) and multiple sclerosis (MS) have a similar clinical phenotype but represent distinct diseases, requiring different therapies. MicroRNAs (miRNAs) are short non-coding RNAs whose expression profiles can serve as diagnostic biomarkers and ...

Last Updated: 2 Nov 2015

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Late-onset neuromyelitis optica spectrum disorder in AQP4-seropositivepatients in a Chinese population.
 

Author(s): Zhifeng Mao, Junjie Yin, Xiaonan Zhong, Zhihua Zhao, Wei Qiu, Zhengqi Lu, Xueqiang Hu

Journal:

 

Increasing rates of AQP4-seropositive neuromyelitis optica spectrum disorder (NMOSD) have been reported in late-onset patients (LONMOSD). However, the full range of clinical differences between early-onset and late-onset variants remain unclear. We describe the clinical features and ...

Last Updated: 4 Sep 2015

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The Clinical Characteristics of Primary Sjogren's Syndrome With Neuromyelitis Optica Spectrum Disorder in China: A STROBE-Compliant Article.
 

Author(s): Lin Qiao, Qian Wang, Yunyun Fei, Wen Zhang, Yan Xu, Yao Zhang, Yan Zhao, Xiaofeng Zeng, Fengchun Zhang

Journal: Medicine (Baltimore). 2015 Jul;94(28):e1145.

 

The aim of the present study was to analyze the clinical characteristics of primary Sjogren's syndrome (pSS) with neuromyelitis optica spectrum disorder (NMOSD). We retrospectively reviewed the medical records of 616 patients who were admitted to the Peking Union Medical College Hospital ...

Last Updated: 18 Jul 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Neuromyelitis optica spectrum disorder" returned 3 free, full-text review articles on human participants. First 3 results:

Use of Advanced Magnetic Resonance Imaging Techniques in Neuromyelitis Optica Spectrum Disorder.
 

Author(s): Stephane Kremer, Felix Renard, Sophie Achard, Marco A Lana-Peixoto, Jacqueline Palace, Nasrin Asgari, Eric C Klawiter, Silvia N Tenembaum, Brenda Banwell, Benjamin M Greenberg, Jeffrey L Bennett, Michael Levy, Pablo Villoslada, Albert Saiz, Kazuo Fujihara, Koon Ho Chan, Sven Schippling, Friedemann Paul, Ho Jin Kim, Jerome de Seze, Jens T Wuerfel, , Philippe Cabre, Romain Marignier, Thomas Tedder, Danielle van Pelt, Simon Broadley, Tanuja Chitnis, Dean Wingerchuk, Lekha Pandit, Maria Isabel Leite, Metha Apiwattanakul, Ingo Kleiter, Naraporn Prayoonwiwat, May Han, Kerstin Hellwig, Katja van Herle, Gareth John, D Craig Hooper, Ichiro Nakashima, Douglas Sato, Michael R Yeaman, Emmanuelle Waubant, Scott Zamvil, Olaf Stüve, Orhan Aktas, Terry J Smith, Anu Jacob, Kevin O'Connor

Journal: JAMA Neurol. 2015 Jul;72(7):815-22.

 

Brain parenchymal lesions are frequently observed on conventional magnetic resonance imaging (MRI) scans of patients with neuromyelitis optica (NMO) spectrum disorder, but the specific morphological and temporal patterns distinguishing them unequivocally from lesions caused by other ...

Last Updated: 14 Jul 2015

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MRI characteristics of neuromyelitis optica spectrum disorder: an international update.
 

Author(s): Ho Jin Kim, Friedemann Paul, Marco A Lana-Peixoto, Silvia Tenembaum, Nasrin Asgari, Jacqueline Palace, Eric C Klawiter, Douglas K Sato, Jérôme de Seze, Jens Wuerfel, Brenda L Banwell, Pablo Villoslada, Albert Saiz, Kazuo Fujihara, Su-Hyun Kim,

Journal: Neurology. 2015 Mar;84(11):1165-73.

 

Since its initial reports in the 19th century, neuromyelitis optica (NMO) had been thought to involve only the optic nerves and spinal cord. However, the discovery of highly specific anti-aquaporin-4 antibody diagnostic biomarker for NMO enabled recognition of more diverse clinical ...

Last Updated: 17 Mar 2015

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Sjögren syndrome and neuromyelitis optica spectrum disorder co-exist in a common autoimmune milieu.
 

Author(s): Diogo C Carvalho, Tauana S Tironi, Denise S Freitas, Rodrigo Kleinpaul, Natalia C Talim, Marco A Lana-Peixoto

Journal: Arq Neuropsiquiatr. 2014 Aug;72(8):619-24.

 

The relationship between Sjögren's syndrome (SS) and neuromyelitis optica spectrum disorder (NMOSD) is not completely understood. We report two patients with both conditions and review 47 other previously reported cases meeting currently accepted diagnostic criteria, from 17 articles ...

Last Updated: 7 Aug 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

A Longitudinal Study of Neuromyelitis Optica and Transverse Myelitis
 

Status: Recruiting

Condition Summary: Neuromyelitis Optica; Neuromyelitis Optica Spectrum Disorder; Transverse Myelitis; Optic Neuritis

 

Last Updated: 5 Sep 2013

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Ublituximab for Acute Neuromyelitis Optica (NMO) Relapses
 

Status: Recruiting

Condition Summary: Neuromyelitis Optica; Neuromyelitis Optica Spectrum Disorder

 

Last Updated: 29 Sep 2015

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