Neurofibroma

Common Name(s)

Neurofibroma

A neurofibroma is a non-cancerous (benign) tumor that develops from the cells and tissues that cover nerves. Some people who develop neurofibromas have a genetic condition known as neurofibromatosis (NF). There are different types of NF, but type 1 is the most common.
 

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Neurofibroma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Neurofibroma" returned 157 free, full-text research articles on human participants. First 3 results:

A neurogenic tumor containing a low-grade malignant peripheral nerve sheath tumor (MPNST) component with loss of p16 expression and homozygous deletion of CDKN2A/p16: a case report showing progression from a neurofibroma to a high-grade MPNST.
 

Author(s): Shogo Tajima, Kenji Koda

Journal:

 

Development of malignant peripheral nerve sheath tumors (MPNSTs) is a stepwise process that involves the alteration of many cell cycle regulators and the double inactivation of the NF1 gene. Inactivation of the TP53 gene and deletion of the CDKN2A/p16 gene are known to play an important ...

Last Updated: 20 Jul 2015

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Solitary preperitoneal neurofibroma: a case report.
 

Author(s): Noureddine Njoumi, Mohamed Elabsi, Gilles Attolou, Hafsa Elouazzani, Faricha Hassan Elalami, Mohamed Rachid Chkoff

Journal:

 

Neurofibroma is a rare benign tumor. The isolated presence of such lesions in the preperitoneal space with no evidence of systemic disease has never been reported in the literature.

Last Updated: 17 Apr 2015

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A childhood case of solitary intrascrotal and extratesticular neurofibroma.
 

Author(s): Asaad Moradi, Babak Kazemzadehazad

Journal:

 

Last Updated: 23 Feb 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Neurofibroma" returned 18 free, full-text review articles on human participants. First 3 results:

Pediatric laryngeal neurofibroma: case report and review of the literature.
 

Author(s): Steven B Chinn, Ryan M Collar, John B McHugh, Norman D Hogikyan, Marc C Thorne

Journal: Int. J. Pediatr. Otorhinolaryngol.. 2014 Jan;78(1):142-7.

 

Presentation of a case of pediatric laryngeal neurofibroma (LNF) and review of the world literature. Comprehensive review of the world literature using Pubmed and Google scholar. Pediatric LNF was identified in 62 cases reported in the world literature. The most common presenting ...

Last Updated: 16 Dec 2013

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Video-assisted thoracoscopic surgery for localized neurofibroma of the esophagus: case report and review of the literature.
 

Author(s): Katsunori Nishikawa, Noburo Omura, Masami Yuda, Yujiro Tanaka, Akira Matsumoto, Yuichiro Tanishima, Yoshiro Ishibashi, Katsuhiko Yanaga, Masahiro Ikegami

Journal: Int Surg. ;98(4):461-5.

 

Esophageal submucosal tumors are less common than other gastrointestinal tract tumors. Leiomyoma is the most common benign esophageal SMT, accounting for more than 70% of these tumors. We report on a case of a 56-year-old woman with a 3-cm diameter midthoracic esophageal submucosal ...

Last Updated: 15 Nov 2013

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Facial plexiform neurofibroma: is it truly just skin deep?
 

Author(s): Wenhui Huang, Wei-Sheng Chong

Journal:

 

A middle-aged Chinese woman presented with a slowly enlarging mass over the right side of her face that was later proven histologically to be a plexiform neurofibroma. This was associated with a localised depression over her right temple. There were no other features of neurofibromatosis-1. ...

Last Updated: 8 Oct 2013

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Natural History Study of Patients With Neurofibromatosis Type I
 

Status: Recruiting

Condition Summary: Neurofibromatosis Type 1; Malignant Peripheral Nerve Sheath Tumor; Plexiform Neurofibroma; Optic Glioma; Neurofibroma

 

Last Updated: 11 May 2016

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Cabozantinib for Plexiform Neurofibromas (PN) in Subjects With NF1 (16 Years +)
 

Status: Recruiting

Condition Summary: NF1; Neurofibromatosis; Plexiform Neurofibromas

 

Last Updated: 8 Mar 2016

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Targeting the Mechanisms Underlying Cutaneous Neurofibroma Formation in NF1: A Clinical Translational Approach.
 

Status: Recruiting

Condition Summary: Cutaneous Neurofibromas; Neurofibromatosis Type 1; Plexiform Neurofibromas

 

Last Updated: 17 May 2016

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