Anthrax

Common Name(s)

Anthrax

Anthrax is a sickness caused by the bacterium Bacillus anthracis. Although anthrax is mostly seen in livestock and wild game, humans can be affected too through contact with sick animals. Anthrax can be passed through open skin wounds, consuming the bacteria, or inhaling it. Symptoms vary from skin sores and nausea to shock. Anthrax can be treated with antibiotics, however inhalation of the bacteria is more serious and sometimes fatal. If you or a family member has been diagnosed with anthrax, talk with your doctor about the most current treatment options available.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Anthrax" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Anthrax" returned 576 free, full-text research articles on human participants. First 3 results:

Mapping the Distribution of Anthrax in Mainland China, 2005-2013.
 

Author(s): Wan-Jun Chen, Sheng-Jie Lai, Yang Yang, Kun Liu, Xin-Lou Li, Hong-Wu Yao, Yu Li, Hang Zhou, Li-Ping Wang, Di Mu, Wen-Wu Yin, Li-Qun Fang, Hong-Jie Yu, Wu-Chun Cao

Journal:

 

Anthrax, a global re-emerging zoonotic disease in recent years is enzootic in mainland China. Despite its significance to the public health, spatiotemporal distributions of the disease in human and livestock and its potential driving factors remain poorly understood.

Last Updated: 21 Apr 2016

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A Comparison of the Adaptive Immune Response between Recovered Anthrax Patients and Individuals Receiving Three Different Anthrax Vaccines.
 

Author(s): Thomas R Laws, Tinatin Kuchuloria, Nazibriola Chitadze, Stephen F Little, Wendy M Webster, Amanda K Debes, Salome Saginadze, Nikoloz Tsertsvadze, Mariam Chubinidze, Robert G Rivard, Shota Tsanava, Edward H Dyson, Andrew J H Simpson, Matthew J Hepburn, Nino Trapaidze

Journal:

 

Several different human vaccines are available to protect against anthrax. We compared the human adaptive immune responses generated by three different anthrax vaccines or by previous exposure to cutaneous anthrax. Adaptive immunity was measured by ELISPOT to count cells that produce ...

Last Updated: 24 Mar 2016

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Randomized, double-blind, active-controlled study evaluating the safety and immunogenicity of three vaccination schedules and two dose levels of AV7909 vaccine for anthrax post-exposure prophylaxis in healthy adults.
 

Author(s): Robert J Hopkins, Gurdyal Kalsi, Victor M Montalvo-Lugo, Mona Sharma, Yukun Wu, Derek D Muse, Eric A Sheldon, Frank C Hampel, Laurence Lemiale

Journal: Vaccine. 2016 Apr;34(18):2096-105.

 

AV7909 vaccine being developed for post-exposure prophylaxis of anthrax disease may require fewer vaccinations and reduced amount of antigen to achieve an accelerated immune response over BioThrax(®) (Anthrax Vaccine Adsorbed). A phase 2, randomized, double-blind, BioThrax vacccine-controlled ...

Last Updated: 29 Mar 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Anthrax" returned 67 free, full-text review articles on human participants. First 3 results:

Roles of Anthrax Toxin Receptor 2 in Anthrax Toxin Membrane Insertion and Pore Formation.
 

Author(s): Jianjun Sun, Pedro Jacquez

Journal:

 

Interaction between bacterial toxins and cellular surface receptors is an important component of the host-pathogen interaction. Anthrax toxin protective antigen (PA) binds to the cell surface receptor, enters the cell through receptor-mediated endocytosis, and forms a pore on the ...

Last Updated: 25 Jan 2016

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Antitoxin Treatment of Inhalation Anthrax: A Systematic Review.
 

Author(s): Eileen Huang, Satish K Pillai, William A Bower, Katherine A Hendricks, Julie T Guarnizo, Jamechia D Hoyle, Susan E Gorman, Anne E Boyer, Conrad P Quinn, Dana Meaney-Delman

Journal: Health Secur. ;13(6):365-77.

 

Concern about use of anthrax as a bioweapon prompted development of novel anthrax antitoxins for treatment. Clinical guidelines for the treatment of anthrax recommend antitoxin therapy in combination with intravenous antimicrobials; however, a large-scale or mass anthrax incident ...

Last Updated: 22 Dec 2015

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Antimicrobial Treatment for Systemic Anthrax: Analysis of Cases from 1945 to 2014 Identified Through a Systematic Literature Review.
 

Author(s): Satish K Pillai, Eileen Huang, Julie T Guarnizo, Jamechia D Hoyle, Stefan Katharios-Lanwermeyer, Theresa K Turski, William A Bower, Katherine A Hendricks, Dana Meaney-Delman

Journal: Health Secur. ;13(6):355-64.

 

Systemic anthrax is associated with high mortality. Current national guidelines, developed for the individualized treatment of systemic anthrax, outline the use of combination intravenous antimicrobials for a minimum of 2 weeks, bactericidal and protein synthesis inhibitor antimicrobials ...

Last Updated: 22 Dec 2015

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Effect of Raxibacumab on Immunogenicity of Anthrax Vaccine Adsorbed
 

Status: Recruiting

Condition Summary: Infections, Bacterial

 

Last Updated: 27 Oct 2016

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BioThrax® (Anthrax) Vaccine in Pregnancy Registry
 

Status: Recruiting

Condition Summary: Pregnancy Complications; Pregnancy Outcome; Congenital Abnormalities

 

Last Updated: 16 Jun 2016

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