Anthrax

Common Name(s)

Anthrax

Anthrax is a sickness caused by the bacterium Bacillus anthracis. Although anthrax is mostly seen in livestock and wild game, humans can be affected too through contact with sick animals. Anthrax can be passed through open skin wounds, consuming the bacteria, or inhaling it. Symptoms vary from skin sores and nausea to shock. Anthrax can be treated with antibiotics, however inhilation of the bacteria is more serious and sometimes fatal.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Anthrax" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Anthrax" returned 470 free, full-text research articles on human participants. First 3 results:

Quantitative models of the dose-response and time course of inhalational anthrax in humans.
 

Author(s): Damon J A Toth, Adi V Gundlapalli, Wiley A Schell, Kenneth Bulmahn, Thomas E Walton, Christopher W Woods, Catherine Coghill, Frank Gallegos, Matthew H Samore, Frederick R Adler

Journal: PLoS Pathog.. 2013 Aug;9(8):e1003555.

 

Anthrax poses a community health risk due to accidental or intentional aerosol release. Reliable quantitative dose-response analyses are required to estimate the magnitude and timeline of potential consequences and the effect of public health intervention strategies under specific ...

Last Updated: 23 Sep 2013

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Evidence of local persistence of human anthrax in the country of georgia associated with environmental and anthropogenic factors.
 

Author(s): Ian T Kracalik, Lile Malania, Nikoloz Tsertsvadze, Julietta Manvelyan, Lela Bakanidze, Paata Imnadze, Shota Tsanava, Jason K Blackburn

Journal:

 

Anthrax is a soil-borne disease caused by the bacterium Bacillus anthracis and is considered a neglected zoonosis. In the country of Georgia, recent reports have indicated an increase in the incidence of human anthrax. Identifying sub-national areas of increased risk may help direct ...

Last Updated: 16 Sep 2013

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Two anthrax cases with soft tissue infection, severe oedema and sepsis in Danish heroin users.
 

Author(s): Lene Russell, Michael Pedersen, Andreas V Jensen, Lillian Marie Søes, Ann-Brit Eg Hansen

Journal:

 

Anthrax had become extremely rare in Europe, but in 2010 an outbreak of anthrax among heroin users in Scotland increased awareness of contaminated heroin as a source of anthrax. We present the first two Danish cases of injectional anthrax and discuss the clinical presentations, which ...

Last Updated: 15 Nov 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Anthrax" returned 49 free, full-text review articles on human participants. First 3 results:

Studies in mice reveal a role for anthrax toxin receptors in matrix metalloproteinase function and extracellular matrix homeostasis.
 

Author(s): Claire Reeves, Pelisa Charles-Horvath, Jan Kitajewski

Journal:

 

The genes encoding Anthrax Toxin Receptors (ANTXRs) were originally identified based on expression in endothelial cells suggesting a role in angiogenesis. The focus of this review is to discuss what has been learned about the physiological roles of these receptors through evaluation ...

Last Updated: 7 Feb 2013

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Anthrax lethal toxin and the induction of CD4 T cell immunity.
 

Author(s): Stephanie Ascough, Rebecca J Ingram, Daniel M Altmann

Journal: Toxins (Basel). 2012 Oct;4(10):878-99.

 

Bacillus anthracis secretes exotoxins which act through several mechanisms including those that can subvert adaptive immunity with respect both to antigen presenting cell and T cell function. The combination of Protective Antigen (PA) and Lethal Factor (LF) forming Lethal Toxin (LT), ...

Last Updated: 19 Nov 2012

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Cellular and physiological effects of anthrax exotoxin and its relevance to disease.
 

Author(s): David E Lowe, Ian J Glomski

Journal:

 

Bacillus anthracis, the causative agent of anthrax, secretes a tri-partite exotoxin that exerts pleiotropic effects on the host. The purification of the exotoxin components, protective antigen, lethal factor, and edema factor allowed the rapid characterization of their physiologic ...

Last Updated: 24 Aug 2012

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 3 Nov 2013

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Glyburide Advantage in Malignant Edema and Stroke - Remedy Pharmaceuticals
 

Status: Recruiting

Condition Summary: Ischemic Stroke; Malignant Edema

 

Last Updated: 3 Jun 2014

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