Anthrax

Common Name(s)

Anthrax

Anthrax is a sickness caused by the bacterium Bacillus anthracis. Although anthrax is mostly seen in livestock and wild game, humans can be affected too through contact with sick animals. Anthrax can be passed through open skin wounds, consuming the bacteria, or inhaling it. Symptoms vary from skin sores and nausea to shock. Anthrax can be treated with antibiotics, however inhalation of the bacteria is more serious and sometimes fatal. If you or a family member has been diagnosed with anthrax, talk with your doctor about the most current treatment options available.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Anthrax" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Anthrax" returned 545 free, full-text research articles on human participants. First 3 results:

Anthrax: a case report.
 

Author(s): Ali Bal, Onur Gökdemir

Journal: J Pak Med Assoc. 2014 Oct;64(10):1201-2.

 

Anthrax is a zoonotic disease caused by a bacterium called Bacillus Anthracis. In humans, it causes a cutaneous, gastro-intestinal and inhalation form of disease. The in-cutaneous form progresses along with skin necrosis and oedema. Since the necroses in the skin are not quite superficial, ...

Last Updated: 31 Mar 2015

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Generation and Characterization of Human Monoclonal Antibodies Targeting Anthrax Protective Antigen following Vaccination with a Recombinant Protective Antigen Vaccine.
 

Author(s): Xiangyang Chi, Jianmin Li, Weicen Liu, Xiaolin Wang, Kexin Yin, Ju Liu, Xiaodong Zai, Liangliang Li, Xiaohong Song, Jun Zhang, Xiaopeng Zhang, Ying Yin, Ling Fu, Junjie Xu, Changming Yu, Wei Chen

Journal: Clin. Vaccine Immunol.. 2015 May;22(5):553-60.

 

The anthrax protective antigen (PA) is the central component of the three-part anthrax toxin, and it is the primary immunogenic component in the approved AVA anthrax vaccine and the "next-generation" recombinant PA (rPA) anthrax vaccines. Animal models have indicated that PA-specific ...

Last Updated: 29 Apr 2015

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Affinity binding of antibodies to supermacroporous cryogel adsorbents with immobilized protein A for removal of anthrax toxin protective antigen.
 

Author(s): Ganesh C Ingavle, Les W J Baillie, Yishan Zheng, Elzbieta K Lis, Irina N Savina, Carol A Howell, Sergey V Mikhalovsky, Susan R Sandeman

Journal: Biomaterials. 2015 May;50():140-53.

 

Polymeric cryogels are efficient carriers for the immobilization of biomolecules because of their unique macroporous structure, permeability, mechanical stability and different surface chemical functionalities. The aim of the study was to demonstrate the potential use of macroporous ...

Last Updated: 4 Mar 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Anthrax" returned 61 free, full-text review articles on human participants. First 3 results:

Statistical analysis, optimization, and prioritization of virtual screening parameters for zinc enzymes including the anthrax toxin lethal factor.
 

Author(s): Kimberly M Maize, Xia Zhang, Elizabeth Ambrose Amin

Journal: Curr Top Med Chem. 2014 ;14(18):2105-14.

 

The anthrax toxin lethal factor (LF) and matrix metalloproteinase-3 (MMP-3, stromelysin-1) are popular zinc metalloenzyme drug targets, with LF primarily responsible for anthrax-related toxicity and host death, while MMP-3 is involved in cancer- and rheumatic disease-related tissue ...

Last Updated: 12 Nov 2014

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Injectional anthrax - new presentation of an old disease.
 

Author(s): T Berger, M Kassirer, A A Aran

Journal:

 

Bacillus anthracis infection (anthrax) has three distinct clinical presentations depending on the route of exposure: cutaneous, gastrointestinal and inhalational anthrax. Each of these can lead to secondary bacteraemia and anthrax meningitis. Since 2009,anthrax has emerged among heroin ...

Last Updated: 20 Aug 2014

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Classification and management of animal anthrax outbreaks based on the source of infection.
 

Author(s): Antonio Fasanella, Rosanna Adone, Martin Hugh-Jones

Journal: Ann. Ist. Super. Sanita. 2014 ;50(2):192-5.

 

Anthrax is a non-contagious infectious disease; it primarily affects herbivores, but all mammals, including humans, can be affected. Humans may contract anthrax directly or indirectly from infected animals. Veterinary surveillance systems, providing information about animal and human ...

Last Updated: 27 Jun 2014

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

A Study of Anthrax Vaccines Px563L and RPA563 in Healthy Adult Subjects
 

Status: Recruiting

Condition Summary: Anthrax

 

Last Updated: 13 Jan 2016

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Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care
 

Status: Recruiting

Condition Summary: Infection; Hypertension; Pain; Reflux; Edema; Hyperlipidemia; Hypotension; Hypercholesterolemia; Sedation; Anxiolysis; Benzodiazepine Withdrawal; Bipolar Disorder; Autistic Disorder; Schizophrenia; Influenza Treatment or Prophylaxis; Acute Decompensated Heart Failure; Stable Angina; Life-threatening Fungal Infections; Nosocomial Pneumonia; Community Acquired Pneumonia; Acute Bacterial Exacerbation of Chronic Bronchitis; Complicated Skin and Skin Structure Infections; Uncomplicated Skin and Skin Structure Infections; Chronic Bacterial Prostatitis; Complicated Urinary Tract Infections; Acute Pyelonephritis; Uncomplicated Urinary Tract Infections; Inhalational Anthrax (Post-Exposure); Infantile Hemangioma; Withdrawal; Inflammation; Bacterial Septicemia; Cytomegalovirus Retinitis; Herpes Simplex Virus; Adenovirus; Brain Swelling; Airway Swelling; Adrenal Insufficiency; Anxiety; Nausea; Vomiting; Convulsions; Muscle Spasms; Seizures; Epilepsy; Bartonellosis; Brucellosis; Cholera; Plague; Psittacosis; Q Fever; Relapsing Fever; Rocky Mountain Spotted Fever; Trachoma; Tularemia; Typhus Fever; Bronchospasm; Cardiac Arrest; Hypersensitivity Reaction; Cyanide Poisoning; Acute Bacterial Sinusitis; Bacterial Meningitis; Sepsis; Gastroparesis; Opioid Addiction; Migraines; Headaches

 

Last Updated: 4 Feb 2016

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