Nephrocalcinosis

Common Name(s)

Nephrocalcinosis

Nephrocalcinosis is a disorder in which there is excess calcium deposited in the kidneys. It is relatively common in premature infants. Individuals may be asymptomatic or have symptoms related to the condition causing nephrocalcinosis. If kidney stones are present, an individual may have blood in the urine; fever and chills; nausea and vomiting; or severe pain in the belly area, sides of the back (flank), groin, or testicles. Later symptoms related to nephrocalcinosis may be associated with chronic kidney failure. It may be caused by use of certain medications or supplements; infection; or any condition that leads to high levels of calcium in the blood or urine including hyperparathyroidism, renal tubular acidosis, Alport syndrome, Bartter syndrome, and a variety of other conditions. Some of the underlying disorders that can cause nephrocalcinosis are genetic, with the inheritance pattern depending on the specific disorder. The goal of treatment is to reduce symptoms and prevent more calcium from being deposited in the kidneys.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Nephrocalcinosis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Nephrocalcinosis" returned 83 free, full-text research articles on human participants. First 3 results:

[Nephrocalcinosis complicating miliary tuberculosis in an infant].
 

Author(s): Jaouad El Maghraoui, Fatima Zahrae Souilmi, Mohamed Hbibi, Tarik Sqalli Houssaini, Mustapha Hida

Journal:

 

Last Updated: 28 Aug 2015

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A Spectrum: Nephrocalcinosis-Nephrolithiasis.
 

Author(s): Ryan S Hsi, Marshall L Stoller

Journal: J. Urol.. 2015 Nov;194(5):1188-9.

 

Last Updated: 19 Oct 2015

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[Nephrocalcinosis and subcutaneous fat necrosis].
 

Author(s): Cláudia Gomes, Luísa Lobo, António Siborro Azevedo, Carla Simão

Journal: Acta Med Port. ;28(1):119-22.

 

Subcutaneous fat necrosis of the newborn is an uncommon, transient and self-healing panniculits. This entity generally follows an uncomplicated course, however there are rare and important complications. The authors present a case of a newborn with subcutaneous fat necrosis complicated ...

Last Updated: 30 Mar 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Nephrocalcinosis" returned 2 free, full-text review articles on human participants. First 3 results:

Discordant Clinical Course of Vitamin-D-Hydroxylase (CYP24A1) Associated Hypercalcemia in Two Adult Brothers With Nephrocalcinosis.
 

Author(s): Tilman Jobst-Schwan, Andrea Pannes, Karl Peter Schlingmann, Kai-Uwe Eckardt, Bodo B Beck, Michael S Wiesener

Journal: Kidney Blood Press. Res.. 2015 ;40(5):443-51.

 

Hypercalcemia can result in nephrocalcinosis/nephrolithiasis and may lead to renal failure. Idiopathic infantile hypercalcemia is caused by mutations of the CYP24A1 gene, which regulates vitamin D activity. Classically infants present with hypercalcemia. Recently, a number of individuals ...

Last Updated: 30 Oct 2015

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Diagnostic examination of the child with urolithiasis or nephrocalcinosis.
 

Author(s): Bernd Hoppe, Markus J Kemper

Journal: Pediatr. Nephrol.. 2010 Mar;25(3):403-13.

 

Urolithiasis and nephrocalcinosis are more frequent in children then currently anticipated, but still remain under- or misdiagnosed in a significant proportion of patients, since symptoms and signs may be subtle or misleading. All children with colicky abdominal pain or macroscopic ...

Last Updated: 25 Jan 2010

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Preterm Infants and Nephrocalcinosis
 

Status: Recruiting

Condition Summary: Prematurity; Nephrocalcinosis; Hypercalciuria

 

Last Updated: 21 Jun 2016

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Randall's Plaque Study: Pathogenesis and Relationship to Nephrolithiasis
 

Status: Recruiting

Condition Summary: Nephrocalcinosis; Renal Calculi; Hypercalciuria; Hyperparathyroidism; Cystinuria

 

Last Updated: 14 Feb 2017

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