Neonatal systemic lupus erythematosus

Common Name(s)

Neonatal systemic lupus erythematosus

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Neonatal systemic lupus erythematosus" for support, advocacy or research.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Neonatal systemic lupus erythematosus" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Neonatal systemic lupus erythematosus" returned 2 free, full-text research articles on human participants. First 3 results:

Brief Report: IRF5 systemic lupus erythematosus risk haplotype is associated with asymptomatic serologic autoimmunity and progression to clinical autoimmunity in mothers of children with neonatal lupus.
 

Author(s): Tharian S Cherian, Silvia N Kariuki, Beverly S Franek, Jill P Buyon, Robert M Clancy, Timothy B Niewold

Journal: Arthritis Rheum.. 2012 Oct;64(10):3383-7.

 

Variation in the interferon regulatory factor 5 (IRF5) gene has been associated with risk of developing systemic lupus erythematosus (SLE), and this association is largely dependent upon anti-Ro autoantibodies. This study was undertaken to determine if the IRF5 genotype is associated ...

Last Updated: 1 Oct 2012

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Evaluation of the risk of anti-SSA/Ro-SSB/La antibody-associated cardiac manifestations of neonatal lupus in fetuses of mothers with systemic lupus erythematosus exposed to hydroxychloroquine.
 

Author(s): Peter M Izmirly, Mimi Y Kim, Carolina Llanos, Phuong U Le, Marta M Guerra, Anca D Askanase, Jane E Salmon, Jill P Buyon

Journal: Ann. Rheum. Dis.. 2010 Oct;69(10):1827-30.

 

Based on the potential involvement of Toll-like receptor (TLR) signalling in the pathogenesis of neonatal lupus (NL), it was hypothesised that fetal exposure to hydroxychloroquine (HCQ), a TLR inhibitor, might reduce the risk of anti-SSA/Ro/SSB/La antibody-associated cardiac manifestations ...

Last Updated: 22 Sep 2010

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Neonatal systemic lupus erythematosus" returned 1 free, full-text review articles on human participants. First 3 results:

Heart involvement in systemic lupus erythematosus, anti-phospholipid syndrome and neonatal lupus.
 

Author(s): A Tincani, C B Rebaioli, M Taglietti, Y Shoenfeld

Journal: Rheumatology (Oxford). 2006 Oct;45 Suppl 4():iv8-13.

 

Cardiac involvement is one of the main complications substantially contributing to the morbidity and mortality of patients suffering from systemic autoimmune diseases. All the anatomical heart structures can be affected, and multiple pathogenic mechanisms have been reported. Non-organ-specific ...

Last Updated: 18 Sep 2006

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

The Research Registry for Neonatal Lupus
 

Status: Recruiting

Condition Summary: Neonatal Lupus; Systemic Lupus Erythematosus; Sjogren's Syndrome; Congenital Heart Block

 

Last Updated: 9 Apr 2013

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Preventive Approach to Congenital Heart Block With Hydroxychloroquine
 

Status: Recruiting

Condition Summary: Congenital Heart Block; Neonatal Lupus; Autoantibody-Associated Heart Block

 

Last Updated: 7 Jun 2013

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Observational Study of the Genetic Architecture of Neutrophil-Mediated Inflammatory Skin Diseases
 

Status: Recruiting

Condition Summary: Other Specified Inflammatory Disorders of Skin or Subcutaneous Tissue; Pyoderma Gangrenosum; Erosive Pustular Dermatosis of the Scalp; Sweet's Syndrome; Behcet's Disease; Bowel-associated Dermatosis-arthritis Syndrome; Pustular Psoriasis; Acute Generalized Exanthematous Pustulosis; Keratoderma Blenorrhagicum; Sneddon-Wilkinson Disease; IgA Pemphigus; Amicrobial Pustulosis of the Folds; Infantile Acropustulosis; Transient Neonatal Pustulosis; Neutrophilic Eccrine Hidradenitis; Rheumatoid Neutrophilic Dermatitis; Neutrophilic Urticaria; Still's Disease; Erythema Marginatum; Unclassified Periodic Fever Syndromes / Autoinflammatory Syndromes; Dermatitis Herpetiformis; Linear IgA Bullous Dermatosis; Bullous Systemic Lupus Erythematosus; Inflammatory Epidermolysis Bullosa Aquisita; Neutrophilic Dermatosis of the Dorsal Hands (Pustular Vasculitis); Small Vessel Vasculitis Including Urticarial Vasculitis; Erythema Elevatum Diutinum; Medium Vessel Vasculitis

 

Last Updated: 11 Jun 2014

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