Necrotizing fasciitis

Common Name(s)

Necrotizing fasciitis

Necrotizing fasciitis is a serious bacterial infection of the skin, subcutaneous tissue (tissue just beneath the skin) and fascia. The infection can be sudden and fast-spreading. The bacteria involved enters the body through an external injury and attacks the surrounding tissues, eventually causing them to die. Early signs include flu-like symptoms and redness or pain around the infection site, followed by very high fever, severe pain, swelling and blistering. If the infection is not treated promptly, it may cause multiple organ failure and death. Treatment typically includes intravenous antibiotics; surgery to remove infected and dead tissue; hyperbaric oxygen therapy; and intravenous immune globulin therapy.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Necrotizing fasciitis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Necrotizing fasciitis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Necrotizing fasciitis" returned 222 free, full-text research articles on human participants. First 3 results:

Clinical Characteristics and Risk Factor Analysis for Lower-Extremity Amputations in Diabetic Patients With Foot Ulcer Complicated by Necrotizing Fasciitis.
 

Author(s): I-Wen Chen, Hui-Mei Yang, Cheng-Hsun Chiu, Jiun-Ting Yeh, Chung-Huei Huang, Yu-Yao Huang

Journal: Medicine (Baltimore). 2015 Nov;94(44):e1957.

 

Patients with diabetes are at a higher risk of having diabetic foot ulcers (DFUs) or necrotizing fasciitis (NF). The present study aims to examine the clinical characteristics and associated risk factors for lower-extremity amputation (LEA) in patients with DFU complicated by NF.We ...

Last Updated: 11 Nov 2015

Go To URL
Streptococcal Necrotizing Fasciitis with Toxic Shock Syndrome and Rapid Fatal Outcome.
 

Author(s): Miroslav Kojič, Dragan Mikič, Darko Nožić, Bojan Rakonjac

Journal: Srp Arh Celok Lek. ;143(7-8):476-9.

 

Streptococcal necrotizing fasciitis (NF) is a serious soft tissue infection with rapid progression of inflammatory process among superficial or deep fascia, systemic host response to infection leading to toxic shock syndrome (TSS), and multiple organ failure. Lethality is high.

Last Updated: 28 Oct 2015

Go To URL
Severe septicemia, necrotizing fasciitis, and peritonitis due to Vibrio vulnificus in a patient undergoing continuous ambulatory peritoneal dialysis: a case report.
 

Author(s): Chang Seong Kim, Eun Hui Bae, Seong Kwon Ma, Soo Wan Kim

Journal:

 

Chronic kidney disease, including end-stage renal disease, has been identified as a possible risk factor for primary septicemia and wound infection by Vibrio vulnificus. However, cases of severe septicemia, necrotizing fasciitis, and peritonitis caused by V. vulnificus in patients ...

Last Updated: 15 Oct 2015

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Necrotizing fasciitis" returned 18 free, full-text review articles on human participants. First 3 results:

Aeromonas sobria necrotizing fasciitis and sepsis in an immunocompromised patient: a case report and review of the literature.
 

Author(s): Savino Spadaro, Angela Berselli, Elisabetta Marangoni, Anna Romanello, Maria Vittoria Colamussi, Riccardo Ragazzi, Silvia Zardi, Carlo Alberto Volta

Journal:

 

Aeromonas veronii biovar sobria is a rare cause of bacteremia, with several studies indicating that this isolate may be of particular clinical significance since it is enterotoxin producing. A wide spectrum of infections has been associated with Aeromonas species in developing countries ...

Last Updated: 26 Sep 2014

Go To URL
Cervical necrotizing fasciitis: report of 6 cases and review of literature.
 

Author(s): P Cruz Toro, À Callejo Castillo, J Tornero Saltó, X González Compta, A Farré, M Maños

Journal: Eur Ann Otorhinolaryngol Head Neck Dis. 2014 Dec;131(6):357-9.

 

Necrotizing fasciitis in the cervical region is a rare entity, characterized by a fulminant infection that causes extensive necrosis of the subcutaneous tissue and fascial planes, with high mortality and morbidity rates. The origin is generally odontogenic or pharyngeal, involving ...

Last Updated: 1 Dec 2014

Go To URL
Necrotizing fasciitis caused by Haemophilus influenzae serotype f.
 

Author(s): Christopher J Arnold, Grant Garrigues, Joseph W St Geme, Daniel J Sexton

Journal: J. Clin. Microbiol.. 2014 Sep;52(9):3471-4.

 

Haemophilus influenzae is a rare cause of soft tissue infection. In this report, we present a case of multifocal necrotizing fasciitis in a healthy adult patient, secondary to Haemophilus influenzae serotype f infection, and we review literature on this rare cause of necrotizing fasciitis.

Last Updated: 21 Aug 2014

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Systems Medicine to Study Necrotizing Soft Tissue Infections (NSTIs).
 

Status: Recruiting

Condition Summary: Soft Tissue Infections; Necrotizing Fasciitis; Necrotizing Soft Tissue Infections

 

Last Updated: 1 Sep 2015

Go to URL
Phase III Efficacy and Safety Study of AB103 in the Treatment of Patients With Necrotizing Soft Tissue Infections
 

Status: Recruiting

Condition Summary: Necrotizing Soft Tissue Infections; Necrotizing Fasciitis; Fournier's Gangrene

 

Last Updated: 14 Jun 2016

Go to URL
Modulation of Biomarkers in Patients With Flesh-eating Bacterial Infections After With Hyperbaric Oxygen Treatment
 

Status: Recruiting

Condition Summary: Necrotizing Soft Tissue Infection; Necrotizing Fasciitis; Gas Gangrene; Fournier Gangrene

 

Last Updated: 15 Jul 2015

Go to URL