Necrotizing fasciitis

Common Name(s)

Necrotizing fasciitis

Necrotizing fasciitis is a serious bacterial infection of the skin, subcutaneous tissue (tissue just beneath the skin) and fascia. The infection can be sudden and fast-spreading. The bacteria involved enters the body through an external injury and attacks the surrounding tissues, eventually causing them to die. Early signs include flu-like symptoms and redness or pain around the infection site, followed by very high fever, severe pain, swelling and blistering. If the infection is not treated promptly, it may cause multiple organ failure and death. Treatment typically includes intravenous antibiotics; surgery to remove infected and dead tissue; hyperbaric oxygen therapy; and intravenous immune globulin therapy.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Necrotizing fasciitis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Necrotizing fasciitis" returned 212 free, full-text research articles on human participants. First 3 results:

Streptococcal Necrotizing Fasciitis with Toxic Shock Syndrome and Rapid Fatal Outcome.
 

Author(s): Miroslav Kojič, Dragan Mikič, Darko Nožić, Bojan Rakonjac

Journal: Srp Arh Celok Lek. ;143(7-8):476-9.

 

Streptococcal necrotizing fasciitis (NF) is a serious soft tissue infection with rapid progression of inflammatory process among superficial or deep fascia, systemic host response to infection leading to toxic shock syndrome (TSS), and multiple organ failure. Lethality is high.

Last Updated: 28 Oct 2015

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Efficacy of direct peripheral blood smears in diagnosing necrotizing fasciitis caused by Streptococcus pyogenes.
 

Author(s): Hideharu Hagiya, Chiaki Kobatake, Naoki Morimoto

Journal: Intern. Med.. 2015 ;54(5):543.

 

Last Updated: 11 Mar 2015

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Severe Mucor necrotizing fasciitis associated to dipyrone-induced agranulocytosis.
 

Author(s): Patricia Salgado, Alejandro Suarez-de-la-Rica, Emilio Maseda, Genaro Maggi, Carmen Hernández-Gancedo, Araceli Lopez-Tofiño, Elena Palacios, Elena Ruiz, Fernando Gilsanz

Journal: Rev Esp Quimioter. 2015 Feb;28(1):58-60.

 

Last Updated: 18 Feb 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Necrotizing fasciitis" returned 18 free, full-text review articles on human participants. First 3 results:

Aeromonas sobria necrotizing fasciitis and sepsis in an immunocompromised patient: a case report and review of the literature.
 

Author(s): Savino Spadaro, Angela Berselli, Elisabetta Marangoni, Anna Romanello, Maria Vittoria Colamussi, Riccardo Ragazzi, Silvia Zardi, Carlo Alberto Volta

Journal:

 

Aeromonas veronii biovar sobria is a rare cause of bacteremia, with several studies indicating that this isolate may be of particular clinical significance since it is enterotoxin producing. A wide spectrum of infections has been associated with Aeromonas species in developing countries ...

Last Updated: 26 Sep 2014

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Cervical necrotizing fasciitis: report of 6 cases and review of literature.
 

Author(s): P Cruz Toro, À Callejo Castillo, J Tornero Saltó, X González Compta, A Farré, M Maños

Journal: Eur Ann Otorhinolaryngol Head Neck Dis. 2014 Dec;131(6):357-9.

 

Necrotizing fasciitis in the cervical region is a rare entity, characterized by a fulminant infection that causes extensive necrosis of the subcutaneous tissue and fascial planes, with high mortality and morbidity rates. The origin is generally odontogenic or pharyngeal, involving ...

Last Updated: 1 Dec 2014

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Necrotizing fasciitis caused by Haemophilus influenzae serotype f.
 

Author(s): Christopher J Arnold, Grant Garrigues, Joseph W St Geme, Daniel J Sexton

Journal: J. Clin. Microbiol.. 2014 Sep;52(9):3471-4.

 

Haemophilus influenzae is a rare cause of soft tissue infection. In this report, we present a case of multifocal necrotizing fasciitis in a healthy adult patient, secondary to Haemophilus influenzae serotype f infection, and we review literature on this rare cause of necrotizing fasciitis.

Last Updated: 21 Aug 2014

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Systems Medicine to Study Necrotizing Soft Tissue Infections (NSTIs).
 

Status: Recruiting

Condition Summary: Soft Tissue Infections; Necrotizing Fasciitis; Necrotizing Soft Tissue Infections

 

Last Updated: 1 Sep 2015

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Phase III Efficacy and Safety Study of AB103 in the Treatment of Patients With Necrotizing Soft Tissue Infections
 

Status: Recruiting

Condition Summary: Necrotizing Soft Tissue Infections; Necrotizing Fasciitis; Fournier's Gangrene

 

Last Updated: 12 Dec 2015

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Immunoglobulin for Necrotizing Soft Tissue Infections: a Randomised Controlled Trial
 

Status: Recruiting

Condition Summary: Necrotizing Soft Tissue Infection; Necrotizing Fasciitis; Gas Gangrene; Fournier Gangrene

 

Last Updated: 8 Apr 2014

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