Necrotizing fasciitis

Common Name(s)

Necrotizing fasciitis

Necrotizing fasciitis is a serious bacterial infection of the skin, subcutaneous tissue (tissue just beneath the skin) and fascia. The infection can be sudden and fast-spreading. The bacteria involved enters the body through an external injury and attacks the surrounding tissues, eventually causing them to die. Early signs include flu-like symptoms and redness or pain around the infection site, followed by very high fever, severe pain, swelling and blistering. If the infection is not treated promptly, it may cause multiple organ failure and death. Treatment typically includes intravenous antibiotics; surgery to remove infected and dead tissue; hyperbaric oxygen therapy; and intravenous immune globulin therapy.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Necrotizing fasciitis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Necrotizing fasciitis" returned 194 free, full-text research articles on human participants. First 3 results:

Efficacy of direct peripheral blood smears in diagnosing necrotizing fasciitis caused by Streptococcus pyogenes.
 

Author(s): Hideharu Hagiya, Chiaki Kobatake, Naoki Morimoto

Journal: Intern. Med.. 2015 ;54(5):543.

 

Last Updated: 11 Mar 2015

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Concurrent emphysematous pyelonephritis and thigh necrotizing fasciitis after intramuscular administration of diclofenac.
 

Author(s): Fateme Shamekhi Amiri, Alireza Foroughi

Journal: Saudi J Kidney Dis Transpl. 2014 Nov;25(6):1263-5.

 

Necrotizing fasciitis (NF) is a rapidly progressive, life-threatening soft tissue infection. NF may result from any injury to the skin or from hematogenous spread. However, con-current emphysematous pyelonephritis and necrotizing fasciitis of the left thigh has not been reported. ...

Last Updated: 14 Nov 2014

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Peristomal necrotizing fasciitis - peculiar evolution of a patient with metachronous colonic tumors.
 

Author(s): It Marin, H Doran, R Zaharia, L Lupu, T Panazan, I Brezean

Journal: Chirurgia (Bucur). ;109(5):693-6.

 

We hereby present a case report of a patient with an unusual neoplasic and surgical history. M.V. is a 54-year-old patient who had been operated, two years ago, for intestinal obstruction caused by a sigmoid tumor; a segmental rectal and sigmoid resection (Hartmann's procedure) was ...

Last Updated: 7 Nov 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Necrotizing fasciitis" returned 16 free, full-text review articles on human participants. First 3 results:

Aeromonas sobria necrotizing fasciitis and sepsis in an immunocompromised patient: a case report and review of the literature.
 

Author(s): Savino Spadaro, Angela Berselli, Elisabetta Marangoni, Anna Romanello, Maria Vittoria Colamussi, Riccardo Ragazzi, Silvia Zardi, Carlo Alberto Volta

Journal:

 

Aeromonas veronii biovar sobria is a rare cause of bacteremia, with several studies indicating that this isolate may be of particular clinical significance since it is enterotoxin producing. A wide spectrum of infections has been associated with Aeromonas species in developing countries ...

Last Updated: 26 Sep 2014

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Necrotizing fasciitis caused by Haemophilus influenzae serotype f.
 

Author(s): Christopher J Arnold, Grant Garrigues, Joseph W St Geme, Daniel J Sexton

Journal: J. Clin. Microbiol.. 2014 Sep;52(9):3471-4.

 

Haemophilus influenzae is a rare cause of soft tissue infection. In this report, we present a case of multifocal necrotizing fasciitis in a healthy adult patient, secondary to Haemophilus influenzae serotype f infection, and we review literature on this rare cause of necrotizing fasciitis.

Last Updated: 21 Aug 2014

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Early diagnosis of necrotizing fasciitis.
 

Author(s): T Goh, L G Goh, C H Ang, C H Wong

Journal: Br J Surg. 2014 Jan;101(1):e119-25.

 

Necrotizing fasciitis is a rapidly progressing skin infection characterized by necrosis of the fascia and subcutaneous tissue, accompanied by severe systemic toxicity. The objective of this systematic review was to identify clinical features and investigations that will aid early diagnosis.

Last Updated: 16 Dec 2013

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Systems Medicine to Study Necrotizing Soft Tissue Infections (NSTIs).
 

Status: Recruiting

Condition Summary: Soft Tissue Infections; Necrotizing Fasciitis; Necrotizing Soft Tissue Infections

 

Last Updated: 1 Sep 2015

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Phase III Efficacy and Safety Study of AB103 in the Treatment of Patients With Necrotizing Soft Tissue Infections
 

Status: Not yet recruiting

Condition Summary: Necrotizing Soft Tissue Infections; Necrotizing Fasciitis; Fournier's Gangrene

 

Last Updated: 6 Aug 2015

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Immunoglobulin for Necrotizing Soft Tissue Infections: a Randomised Controlled Trial
 

Status: Recruiting

Condition Summary: Necrotizing Soft Tissue Infection; Necrotizing Fasciitis; Gas Gangrene; Fournier Gangrene

 

Last Updated: 8 Apr 2014

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