Necrotizing fasciitis

Common Name(s)

Necrotizing fasciitis

Necrotizing fasciitis is a serious bacterial infection of the skin, subcutaneous tissue (tissue just beneath the skin) and fascia. The infection can be sudden and fast-spreading. The bacteria involved enters the body through an external injury and attacks the surrounding tissues, eventually causing them to die. Early signs include flu-like symptoms and redness or pain around the infection site, followed by very high fever, severe pain, swelling and blistering. If the infection is not treated promptly, it may cause multiple organ failure and death. Treatment typically includes intravenous antibiotics; surgery to remove infected and dead tissue; hyperbaric oxygen therapy; and intravenous immune globulin therapy.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Necrotizing fasciitis" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Necrotizing fasciitis" returned 230 free, full-text research articles on human participants. First 3 results:

Successful Treatment of a Case of Necrotizing Fasciitis due to Vibrio vulnificus in a Cold Climate in Japan.
 

Author(s): Chiho Kitamura, Yoichi Yamauchi, Tomoya Yamaguchi, Yoshihisa Aida, Katsunori Ito, Yoshiya Ishizawa, Kyoji Saitoh, Tomonori Kasai, Motoki Ohnishi

Journal: Intern. Med.. 2016 ;55(8):1007-10.

 

Vibrio vulnificus infection often occurs in warm regions, frequently leading to necrotizing fasciitis, sepsis, and death. We herein report a rare case presenting in a cold climate region in northern Japan, Aomori district, of a V. vulnificus infection complicated by necrotizing fasciitis ...

Last Updated: 18 Apr 2016

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Necrotizing fasciitis due to Streptococcus mitis caused by accidental human bite.
 

Author(s): Aliye Bastug, Sumeyye Kislak, Nevzat Mehmet Mutlu, Zeynep Nur Akcaboy, Asude Koksal, Ahmet Sertcelik, Ramazan Erkin Ünlü, Esragul Akinci, Hurrem Bodur

Journal:

 

Human bite wounds are more prone to infection than animal bites, which may cause necrotizing soft tissue infections such as myositis, fasciitis. Both aerobic and anaerobic microorganisms may be responsible, including Streptococcus spp., Staphylococcus aureus, Peptostreptococcus spp. ...

Last Updated: 2 Feb 2016

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Successful Treatment of Necrotizing Fasciitis after Rectal Surgery with the Application of a Negative-pressure Wound Therapy: A Case Study.
 

Author(s): Yoshiaki Mizuguchi, Satoshi Matsumoto, Hayato Kan, Michihiro Koizumi, Shou Kuriyama, Eiji Uchida

Journal: J Nippon Med Sch. 2015 ;82(6):290-4.

 

Necrotizing fasciitis (NF) is an aggressive soft tissue infection that involves the deep fascia and is characterized by the extensive deterioration of the surrounding tissue. Immediate recognition and aggressive treatment, including debridement and systemic antibiotics, are mandatory ...

Last Updated: 29 Jan 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Necrotizing fasciitis" returned 18 free, full-text review articles on human participants. First 3 results:

Aeromonas sobria necrotizing fasciitis and sepsis in an immunocompromised patient: a case report and review of the literature.
 

Author(s): Savino Spadaro, Angela Berselli, Elisabetta Marangoni, Anna Romanello, Maria Vittoria Colamussi, Riccardo Ragazzi, Silvia Zardi, Carlo Alberto Volta

Journal:

 

Aeromonas veronii biovar sobria is a rare cause of bacteremia, with several studies indicating that this isolate may be of particular clinical significance since it is enterotoxin producing. A wide spectrum of infections has been associated with Aeromonas species in developing countries ...

Last Updated: 26 Sep 2014

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Cervical necrotizing fasciitis: report of 6 cases and review of literature.
 

Author(s): P Cruz Toro, À Callejo Castillo, J Tornero Saltó, X González Compta, A Farré, M Maños

Journal: Eur Ann Otorhinolaryngol Head Neck Dis. 2014 Dec;131(6):357-9.

 

Necrotizing fasciitis in the cervical region is a rare entity, characterized by a fulminant infection that causes extensive necrosis of the subcutaneous tissue and fascial planes, with high mortality and morbidity rates. The origin is generally odontogenic or pharyngeal, involving ...

Last Updated: 1 Dec 2014

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Necrotizing fasciitis caused by Haemophilus influenzae serotype f.
 

Author(s): Christopher J Arnold, Grant Garrigues, Joseph W St Geme, Daniel J Sexton

Journal: J. Clin. Microbiol.. 2014 Sep;52(9):3471-4.

 

Haemophilus influenzae is a rare cause of soft tissue infection. In this report, we present a case of multifocal necrotizing fasciitis in a healthy adult patient, secondary to Haemophilus influenzae serotype f infection, and we review literature on this rare cause of necrotizing fasciitis.

Last Updated: 21 Aug 2014

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Factors Associated With Complications of Cervical Necrotizing Fasciitis
 

Status: Recruiting

Condition Summary: Cervical Necrotizing Fasciitis

 

Last Updated: 25 Jul 2016

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Severe Soft Tissue Infections: Perspectives of Patients and Significant Others
 

Status: Recruiting

Condition Summary: Necrotizing Fasciitis

 

Last Updated: 8 Aug 2016

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Systems Medicine to Study Necrotizing Soft Tissue Infections (NSTIs).
 

Status: Recruiting

Condition Summary: Soft Tissue Infections; Necrotizing Fasciitis; Necrotizing Soft Tissue Infections

 

Last Updated: 1 Sep 2015

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