Necrotizing fasciitis

Common Name(s)

Necrotizing fasciitis

Necrotizing fasciitis is a serious bacterial infection of the skin, subcutaneous tissue (tissue just beneath the skin) and fascia. The infection can be sudden and fast-spreading. The bacteria involved enters the body through an external injury and attacks the surrounding tissues, eventually causing them to die. Early signs include flu-like symptoms and redness or pain around the infection site, followed by very high fever, severe pain, swelling and blistering. If the infection is not treated promptly, it may cause multiple organ failure and death. Treatment typically includes intravenous antibiotics; surgery to remove infected and dead tissue; hyperbaric oxygen therapy; and intravenous immune globulin therapy.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Necrotizing fasciitis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Necrotizing fasciitis" returned 182 free, full-text research articles on human participants. First 3 results:

Skin grafting for necrotizing fasciitis in a child with nephrotic syndrome.
 

Author(s): Narendra Bagri, Abhijeet Saha, Nandkishore K Dubey, Ashish Rai, Sameek Bhattacharya

Journal: Iran J Kidney Dis. 2013 Nov;7(6):496-8.

 

Necrotizing fasciitis is a rare complication of nephrotic syndrome in children, with a high mortality rate. We report a case with successful outcome with judicious intravenous antibiotics and skin grafting of the bilateral lower thighs.

Last Updated: 18 Nov 2013

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Fatal necrotizing fasciitis following sclerotherapy for haemorrhoids.
 

Author(s): Buddhike Indrasena, Lakmal Doratiyawa

Journal: Chin. Med. J.. 2013 Mar;126(5):982-3.

 

Last Updated: 15 Mar 2013

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Risk factors, microbiological findings and outcomes of necrotizing fasciitis in New Zealand: a retrospective chart review.
 

Author(s): Dilip Kumar Das, Michael G Baker, Kamalesh Venugopal

Journal:

 

The incidence and mortality from necrotizing fasciitis (NF) are increasing in New Zealand (NZ). Triggered by a media report that traditional Samoan tattooing was causing NF, we conducted a chart review to investigate the role of this and other predisposing and precipitating factors ...

Last Updated: 7 Jan 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Necrotizing fasciitis" returned 11 free, full-text review articles on human participants. First 3 results:

Early diagnosis of necrotizing fasciitis.
 

Author(s): T Goh, L G Goh, C H Ang, C H Wong

Journal: Br J Surg. 2014 Jan;101(1):e119-25.

 

Necrotizing fasciitis is a rapidly progressing skin infection characterized by necrosis of the fascia and subcutaneous tissue, accompanied by severe systemic toxicity. The objective of this systematic review was to identify clinical features and investigations that will aid early diagnosis.

Last Updated: 16 Dec 2013

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Necrotizing fasciitis: eight-year experience and literature review.
 

Author(s): Jinn-Ming Wang, Hwee-Kheng Lim

Journal: Braz J Infect Dis. ;18(2):137-43.

 

To describe clinical, laboratory, microbiological features, and outcomes of necrotizing fasciitis.

Last Updated: 18 Mar 2014

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Necrotizing Fasciitis - report of ten cases and review of recent literature.
 

Author(s): S Al Shukry, J Ommen

Journal: J Med Life. 2013 Jun;6(2):189-94.

 

Necrotizing fasciitis is an uncommon disease that results in gross morbidity and mortality if not diagnosed and treated in its early stages. At onset, however, it is difficult to differentiate from other superficial skin conditions such as cellulitis. Family physicians must have a ...

Last Updated: 1 Aug 2013

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Systems Medicine to Study NSTIs
 

Status: Recruiting

Condition Summary: Soft Tissue Infections; Necrotizing Fasciitis; Necrotizing Soft Tissue Infections

 

Last Updated: 28 Oct 2013

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Biomarkers in Patients With Flesh-eating Bacterial Infections
 

Status: Recruiting

Condition Summary: Necrotizing Soft Tissue Infection; Necrotizing Fasciitis; Gas Gangrene; Fournier Gangrene

 

Last Updated: 1 Jul 2014

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Immunoglobulin for Necrotizing Soft Tissue Infections: a Randomised Controlled Trial
 

Status: Recruiting

Condition Summary: Necrotizing Soft Tissue Infection; Necrotizing Fasciitis; Gas Gangrene; Fournier Gangrene

 

Last Updated: 8 Apr 2014

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