Necrotizing fasciitis

Common Name(s)

Necrotizing fasciitis

Necrotizing fasciitis is a serious bacterial infection of the skin, subcutaneous tissue (tissue just beneath the skin) and fascia. The infection can be sudden and fast-spreading. The bacteria involved enters the body through an external injury and attacks the surrounding tissues, eventually causing them to die. Early signs include flu-like symptoms and redness or pain around the infection site, followed by very high fever, severe pain, swelling and blistering. If the infection is not treated promptly, it may cause multiple organ failure and death. Treatment typically includes intravenous antibiotics; surgery to remove infected and dead tissue; hyperbaric oxygen therapy; and intravenous immune globulin therapy.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Necrotizing fasciitis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Necrotizing fasciitis" returned 189 free, full-text research articles on human participants. First 3 results:

Peristomal necrotizing fasciitis - peculiar evolution of a patient with metachronous colonic tumors.
 

Author(s): It Marin, H Doran, R Zaharia, L Lupu, T Panazan, I Brezean

Journal: Chirurgia (Bucur). ;109(5):693-6.

 

We hereby present a case report of a patient with an unusual neoplasic and surgical history. M.V. is a 54-year-old patient who had been operated, two years ago, for intestinal obstruction caused by a sigmoid tumor; a segmental rectal and sigmoid resection (Hartmann's procedure) was ...

Last Updated: 7 Nov 2014

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Necrotizing fasciitis--a diagnostic dilemma: two case reports.
 

Author(s): Mitrakrishnan Rayno Navinan, Jevon Yudhishdran, Thambyaiah Kandeepan, Aruna Kulatunga

Journal:

 

Necrotizing soft tissue infections can affect various tissue planes. Although predisposing etiologies are many, they mostly center on impaired immunity occurring directly or indirectly and loss of integrity of protective barriers which predispose to infection. The nonspecific presentation ...

Last Updated: 9 Jul 2014

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Life-threatening rupture of an external iliac artery pseudoaneurysm caused by necrotizing fasciitis following laparoscopic radical cystectomy: a case report.
 

Author(s): Shinro Hata, Ryuta Satoh, Toshitaka Shin, Kenichi Mori, Yasuhiro Sumino, Fuminori Satoh, Hiromitsu Mimata

Journal:

 

Pseudoaneurysms are caused by trauma, tumors, infections, vasculitis, atherosclerosis and iatrogenic complications. In this paper, we report about a patient with rupture of an external iliac artery pseudoaneurysm, which lead to hemorrhagic shock, after undergoing laparoscopic radical ...

Last Updated: 4 Jun 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Necrotizing fasciitis" returned 12 free, full-text review articles on human participants. First 3 results:

Early diagnosis of necrotizing fasciitis.
 

Author(s): T Goh, L G Goh, C H Ang, C H Wong

Journal: Br J Surg. 2014 Jan;101(1):e119-25.

 

Necrotizing fasciitis is a rapidly progressing skin infection characterized by necrosis of the fascia and subcutaneous tissue, accompanied by severe systemic toxicity. The objective of this systematic review was to identify clinical features and investigations that will aid early diagnosis.

Last Updated: 16 Dec 2013

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MRI in necrotizing fasciitis of the extremities.
 

Author(s): S Z Ali, S Srinivasan, W C G Peh

Journal: Br J Radiol. 2014 Jan;87(1033):20130560.

 

Necrotizing fasciitis is a life-threatening soft-tissue infection of bacterial origin, which involves mainly the deep fascia. Early recognition of this condition may be hampered by the uncommon nature of the disease and non-specificity of initial clinical signs and symptoms in less ...

Last Updated: 20 Dec 2013

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Necrotizing fasciitis: eight-year experience and literature review.
 

Author(s): Jinn-Ming Wang, Hwee-Kheng Lim

Journal: Braz J Infect Dis. ;18(2):137-43.

 

To describe clinical, laboratory, microbiological features, and outcomes of necrotizing fasciitis.

Last Updated: 18 Mar 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Systems Medicine to Study NSTIs
 

Status: Recruiting

Condition Summary: Soft Tissue Infections; Necrotizing Fasciitis; Necrotizing Soft Tissue Infections

 

Last Updated: 28 Oct 2013

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Biomarkers in Patients With Flesh-eating Bacterial Infections
 

Status: Recruiting

Condition Summary: Necrotizing Soft Tissue Infection; Necrotizing Fasciitis; Gas Gangrene; Fournier Gangrene

 

Last Updated: 10 Oct 2014

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Immunoglobulin for Necrotizing Soft Tissue Infections: a Randomised Controlled Trial
 

Status: Recruiting

Condition Summary: Necrotizing Soft Tissue Infection; Necrotizing Fasciitis; Gas Gangrene; Fournier Gangrene

 

Last Updated: 8 Apr 2014

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