Nasopharyngeal carcinoma

Common Name(s)

Nasopharyngeal carcinoma

Nasopharyngeal carcinoma (NPC, NPCA) is a multifactorial malignancy associated with both genetic and environmental factors. The cancer arises from the epithelium of the nasopharynx. The Epstein-Barr virus has been implicated ({12:Tse et al., 2009}). Genetic Heterogeneity of Susceptibility to Nasopharyngeal Carcinoma NPCA1 maps to chromosome 4p. NPCA2 ({161550}) maps to chromosome 6p21. NPCA3 ({617075}) is associated with variation in the MST1R gene ({600168}) on chromosome 3p21.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Nasopharyngeal carcinoma" for support, advocacy or research.

Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

Last Updated: 29 Jul 2015

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Nasopharyngeal carcinoma" for support, advocacy or research.

Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

http://www.CancerHopeNetwork.org

Last Updated: 29 Jul 2015

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Nasopharyngeal carcinoma" returned 1960 free, full-text research articles on human participants. First 3 results:

Central nervous system leukemia in a patient with concurrent nasopharyngeal carcinoma and acute myeloid leukaemia: A case report.
 

Author(s): Jun-Qing Liu, Wen-Yuan Mai, Si-Ben Wang, Yin-Jun Lou, Sen-Xiang Yan, Jie Jin, Wei-Lai Xu

Journal: Medicine (Baltimore). 2017 Dec;96(52):e9199.

 

Concurrent case of nasopharyngeal carcinoma (NPC) and acute myeloid leukemia (AML) has not been reported. Here, we report a case of NPC, who was concurrently suffered from AML one mother after the NPC diagnosis.

Last Updated: 31 Dec 1969

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Optimal cumulative cisplatin dose in nasopharyngeal carcinoma patients receiving additional induction chemotherapy.
 

Author(s): Jia-Wei Lv, Zhen-Yu Qi, Guan-Qun Zhou, Xiao-Jun He, Yu-Pei Chen, Yan-Ping Mao, Lei Chen, Ling-Long Tang, Wen-Fei Li, Ai-Hua Lin, Jun Ma, Ying Sun

Journal: Cancer Sci.. 2018 Mar;109(3):751-763.

 

To clarify the optimal cumulative cisplatin dose (CCD) in locoregionally-advanced nasopharyngel carcinoma (NPC) patients receiving induction chemotherapy (IC) plus concurrent chemoradiotherapy (CCRT). Using the NPC-specific database from the established big-data intelligence platform ...

Last Updated: 31 Dec 1969

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Nasopharyngeal carcinoma with central nervous system metastases: Two case reports and a review of the literature.
 

Author(s): Chunying Shen, Hongmei Ying, Xueguan Lu, Chaosu Hu

Journal: Medicine (Baltimore). 2017 Dec;96(49):e9175.

 

Central nervous system (CNS) metastases are rarely seen in patients with nasopharyngeal carcinoma (NPC).

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Nasopharyngeal carcinoma" returned 105 free, full-text review articles on human participants. First 3 results:

Functions and Roles of Long-Non-Coding RNAs in Human Nasopharyngeal Carcinoma.
 

Author(s): JingJing Wu, Swei Sunny Hann

Journal: Cell. Physiol. Biochem.. 2018 ;45(3):1191-1204.

 

Nasopharyngeal carcinoma (NPC) is one of the most common cancers originating in the nasopharynx and occurring at high frequency in South-eastern Asia and North Africa. Long non-coding RNAs (lncRNAs) are a class of non-protein-coding RNA molecules and key regulators of developmental, ...

Last Updated: 31 Dec 1969

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Modulation of the tumor microenvironment by Epstein-Barr virus latent membrane protein 1 in nasopharyngeal carcinoma.
 

Author(s): Tomokazu Yoshizaki, Satoru Kondo, Kazuhira Endo, Yosuke Nakanishi, Mitsuharu Aga, Eiji Kobayashi, Nobuyuki Hirai, Hisashi Sugimoto, Miyako Hatano, Takayoshi Ueno, Kazuya Ishikawa, Naohiro Wakisaka

Journal: Cancer Sci.. 2018 Feb;109(2):272-278.

 

Latent membrane protein 1 (LMP1) is a primary oncogene encoded by the Epstein-Barr virus, and various portions of LMP1 are detected in nasopharyngeal carcinoma (NPC) tumor cells. LMP1 has been extensively studied since the discovery of its transforming property in 1985. LMP1 promotes ...

Last Updated: 31 Dec 1969

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Prognostic role of C-reactive protein in patients with nasopharyngeal carcinoma: A meta-analysis and literature review.
 

Author(s): Yi Fang, Chang Xu, Peng Wu, Ling-Hao Zhang, Da-Wei Li, Jie-Hao Sun, Wen-Feng Li, Zhi-Su Liao

Journal: Medicine (Baltimore). 2017 Nov;96(45):e8463.

 

C-reactive protein (CRP) has been shown to be associated with several tumors. However, its association with nasopharyngeal carcinoma (NPC) is not well characterized. We performed a literature review and meta-analysis to assess the prognostic relevance of elevated CRP levels in patients with NPC.

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

TPF+CCRT vs.CCRT+PF in High Risk Nasopharyngeal Carcinoma
 

Status: Recruiting

Condition Summary: Nasopharyngeal Carcinoma

 

Last Updated: 13 Nov 2017

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Phase Ⅲ Trial of Adjuvant Chemotherapy in Patients With N2-3 Nasopharyngeal Carcinoma
 

Status: Recruiting

Condition Summary: Nasopharyngeal Carcinoma

 

Last Updated: 9 Nov 2017

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Donafenib Monotherapy for Previously Treated Metastatic Nasopharyngeal Carcinoma
 

Status: Recruiting

Condition Summary: Nasopharyngeal Carcinoma

 

Last Updated: 15 Oct 2017

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