Nasopharyngeal carcinoma

Common Name(s)

Nasopharyngeal carcinoma

Nasopharyngeal carcinoma (NPC, NPCA) is a multifactorial malignancy associated with both genetic and environmental factors. The cancer arises from the epithelium of the nasopharynx. The Epstein-Barr virus has been implicated ({12:Tse et al., 2009}). A susceptibility locus for nasopharyngeal carcinoma (NPCA1) has been mapped to chromosome 4p. A second locus, NPCA2 ({161550}), has been mapped to chromosome 6p21.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Nasopharyngeal carcinoma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Nasopharyngeal carcinoma" returned 1218 free, full-text research articles on human participants. First 3 results:

Plasma Epstein-Barr virus DNA as a biomarker for nasopharyngeal carcinoma.
 

Author(s): K C Allen Chan

Journal: Chin J Cancer. 2014 Dec;33(12):598-603.

 

Nasopharyngeal carcinoma (NPC) is common in southern China and Southeast Asia. Epstein-Barr virus (EBV) infection is an important etiology for NPC, and EBV genome can be detected in almost all tumor tissues of NPC in this region. Plasma EBV DNA, when quantitatively analyzed using ...

Last Updated: 10 Dec 2014

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Epstein-Barr virus and nasopharyngeal carcinoma.
 

Author(s): Lawrence S Young, Christopher W Dawson

Journal: Chin J Cancer. 2014 Dec;33(12):581-90.

 

Since its discovery 50 years ago, Epstein-Barr virus (EBV) has been linked to the development of cancers originating from both lymphoid and epithelial cells. Approximately 95% of the world's population sustains an asymptomatic, life-long infection with EBV. The virus persists in the ...

Last Updated: 10 Dec 2014

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The Glasgow Prognostic Score predicts poor survival in cisplatin-based treated patients with metastatic nasopharyngeal carcinoma.
 

Author(s): Cui Chen, Peng Sun, Qiang-sheng Dai, Hui-wen Weng, He-ping Li, Sheng Ye

Journal:

 

Several inflammation-based prognostic scoring systems, including Glasgow Prognostic Score (GPS), neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) have been reported to predict survival in many malignancies, whereas their role in metastatic nasopharyngeal ...

Last Updated: 14 Nov 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Nasopharyngeal carcinoma" returned 55 free, full-text review articles on human participants. First 3 results:

The role of microRNAs in nasopharyngeal carcinoma.
 

Author(s): Gongjun Tan, Xiaowei Tang, Faqing Tang

Journal: Tumour Biol.. 2015 Jan;36(1):69-79.

 

Nasopharyngeal carcinoma (NPC), a distinct type of head and neck cancer, is prevalent in Southeast Asia and southern China. Ethnic background and environmental factors contribute to the development of NPC, further complicating its pathogenesis. An increasing body of evidence indicates ...

Last Updated: 3 Feb 2015

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Cancer stem-like cell: a novel target for nasopharyngeal carcinoma therapy.
 

Author(s): Pingpin Wei, Man Niu, Suming Pan, Yanhong Zhou, Cijun Shuai, Jing Wang, Shuping Peng, Guiyuan Li

Journal: Stem Cell Res Ther. 2014 ;5(2):44.

 

Nasopharyngeal carcinoma (NPC) is the most common cancer originating in the nasopharynx, and is extremely common in southern regions of China. Although the standard combination of radiotherapy and chemotherapy has improved the efficiency in patients with NPC, relapse and early metastasis ...

Last Updated: 28 Aug 2014

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Nasopharyngeal adenoid cystic carcinoma: a case report and review of the literature.
 

Author(s): Yan-Fang Liang, Bin Kong, Wen-Yu Xiang, Jian-Bo Ruan, Ling-Mei Wang, Can Chen, Wei-Hua Xu, Qiu-Liang Wu, Jin-Cheng Zeng, Jun-Fa Xu

Journal:

 

ACC derived from nasopharyngeal epithelial cells is rare, usually benign. In this article, we reported a nasopharyngeal adenoid cystic carcinoma (NACC) in a 31-year-old woman with a symptom of hoarseness, headache, epistaxis slightly, diplopia, facial numbness and dysphagia near 3 ...

Last Updated: 14 Aug 2014

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Famitinib in Treating Patients With Recurrent and/or Metastatic Nasopharyngeal Carcinoma (NPC)
 

Status: Recruiting

Condition Summary: Recurrent Nasopharyngeal Carcinoma; Metastatic Nasopharyngeal Carcinoma

 

Last Updated: 8 Feb 2012

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Retrospective Study About Nasopharyngeal Carcinoma at C. S. Parc Tauli
 

Status: Not yet recruiting

Condition Summary: Nasopharyngeal Carcinoma

 

Last Updated: 23 Jul 2014

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Atorvastatin in Preventing Nasopharyngeal Carcinoma Patients Receiving Radiotherapy From Carotid Stenosis
 

Status: Recruiting

Condition Summary: Nasopharyngeal Carcinoma; Radiation Therapy Complication

 

Last Updated: 7 Feb 2014

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