Nasopharyngeal carcinoma

Common Name(s)

Nasopharyngeal carcinoma

Nasopharyngeal carcinoma (NPC, NPCA) is a multifactorial malignancy associated with both genetic and environmental factors. The cancer arises from the epithelium of the nasopharynx. The Epstein-Barr virus has been implicated ({12:Tse et al., 2009}). A susceptibility locus for nasopharyngeal carcinoma (NPCA1) has been mapped to chromosome 4p. A second locus, NPCA2 ({161550}), has been mapped to chromosome 6p21.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Nasopharyngeal carcinoma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Nasopharyngeal carcinoma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Nasopharyngeal carcinoma" returned 1198 free, full-text research articles on human participants. First 3 results:

Nasopharyngeal carcinoma presenting with rapidly progressive severe visual disturbance: a case report.
 

Author(s): Yoshinobu Kamio, Naoto Sakai, Goro Takahashi, Satoshi Baba, Hiroki Namba

Journal:

 

Nasopharyngeal carcinoma is one of the most difficult tumors to diagnose correctly at the initial phase because of the occasional lack of nasal symptoms. The perineural spread of the trigeminal nerve is one of the most common and important routes in the intracranial paracavernous ...

Last Updated: 12 Nov 2014

Go To URL
Evaluation and integration of genetic signature for prediction risk of nasopharyngeal carcinoma in Southern China.
 

Author(s): Xiuchan Guo, Cheryl A Winkler, Ji Li, Li Guan, Minzhong Tang, Jian Liao, Hong Deng, Guy de Thé, Yi Zeng, Stephen J O'Brien

Journal: Biomed Res Int. 2014 ;2014():434072.

 

Genetic factors, as well as environmental factors, play a role in development of nasopharyngeal carcinoma (NPC). A number of single nucleotide polymorphisms (SNPs) have been reported to be associated with NPC. To confirm these genetic associations with NPC, two independent case-control ...

Last Updated: 2 Sep 2014

Go To URL
Safety and efficacy of S-1 chemotherapy in recurrent and metastatic nasopharyngeal carcinoma patients after failure of platinum-based chemotherapy: multi-institutional retrospective analysis.
 

Author(s): Pei-Jian Peng, Hua Cheng, Xue-Qing Ou, Lin-Juan Zeng, Xuan Wu, Yu-Meng Liu, Zhong Lin, Yan-Na Tang, Si-Yang Wang, Hong-Yu Zhang, Zhi-Bin Chen

Journal:

 

This retrospective study evaluates the efficacy and safety of S-1 chemotherapy for recurrent and metastatic nasopharyngeal carcinoma patients after failure of platinum-based chemotherapy.

Last Updated: 25 Aug 2014

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Nasopharyngeal carcinoma" returned 54 free, full-text review articles on human participants. First 3 results:

The role of microRNAs in nasopharyngeal carcinoma.
 

Author(s): Gongjun Tan, Xiaowei Tang, Faqing Tang

Journal: Tumour Biol.. 2015 Jan;36(1):69-79.

 

Nasopharyngeal carcinoma (NPC), a distinct type of head and neck cancer, is prevalent in Southeast Asia and southern China. Ethnic background and environmental factors contribute to the development of NPC, further complicating its pathogenesis. An increasing body of evidence indicates ...

Last Updated: 3 Feb 2015

Go To URL
Nasopharyngeal adenoid cystic carcinoma: a case report and review of the literature.
 

Author(s): Yan-Fang Liang, Bin Kong, Wen-Yu Xiang, Jian-Bo Ruan, Ling-Mei Wang, Can Chen, Wei-Hua Xu, Qiu-Liang Wu, Jin-Cheng Zeng, Jun-Fa Xu

Journal:

 

ACC derived from nasopharyngeal epithelial cells is rare, usually benign. In this article, we reported a nasopharyngeal adenoid cystic carcinoma (NACC) in a 31-year-old woman with a symptom of hoarseness, headache, epistaxis slightly, diplopia, facial numbness and dysphagia near 3 ...

Last Updated: 14 Aug 2014

Go To URL
The Interleukin-18 promoter -607C>A polymorphism contributes to nasopharyngeal carcinoma risk: evidence from a meta-analysis including 1,886 subjects.
 

Author(s): Xu-Guang Guo, Yong Xia

Journal: Asian Pac. J. Cancer Prev.. 2013 ;14(12):7577-81.

 

The interleukin-18 promoter -607C>A gene polymorphism may be related to nasopharyngeal carcinoma (NPC) risk but the results of individual studies remain conflicting. A meta-analysis including 1,886 subjects from five individual studies was therefore performed to provide a more accurate ...

Last Updated: 27 Jan 2014

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Famitinib in Treating Patients With Recurrent and/or Metastatic Nasopharyngeal Carcinoma (NPC)
 

Status: Recruiting

Condition Summary: Recurrent Nasopharyngeal Carcinoma; Metastatic Nasopharyngeal Carcinoma

 

Last Updated: 8 Feb 2012

Go to URL
Retrospective Study About Nasopharyngeal Carcinoma at C. S. Parc Tauli
 

Status: Not yet recruiting

Condition Summary: Nasopharyngeal Carcinoma

 

Last Updated: 23 Jul 2014

Go to URL
Atorvastatin in Preventing Nasopharyngeal Carcinoma Patients Receiving Radiotherapy From Carotid Stenosis
 

Status: Recruiting

Condition Summary: Nasopharyngeal Carcinoma; Radiation Therapy Complication

 

Last Updated: 7 Feb 2014

Go to URL