Nasopharyngeal carcinoma

Common Name(s)

Nasopharyngeal carcinoma

Nasopharyngeal carcinoma (NPC, NPCA) is a multifactorial malignancy associated with both genetic and environmental factors. The cancer arises from the epithelium of the nasopharynx. The Epstein-Barr virus has been implicated ({12:Tse et al., 2009}). A susceptibility locus for nasopharyngeal carcinoma (NPCA1) has been mapped to chromosome 4p. A second locus, NPCA2 ({161550}), has been mapped to chromosome 6p21.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Nasopharyngeal carcinoma" for support, advocacy or research.

Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

Last Updated: 29 Jul 2015

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Nasopharyngeal carcinoma" for support, advocacy or research.

Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

http://www.CancerHopeNetwork.org

Last Updated: 29 Jul 2015

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Nasopharyngeal carcinoma" returned 1671 free, full-text research articles on human participants. First 3 results:

Unidimensional Measurement May Evaluate Target Lymph Nodal Response After Induction Chemotherapy for Nasopharyngeal Carcinoma.
 

Author(s): Chuanben Chen, Mingwei Zhang, Yuanji Xu, Qiuyuan Yue, Penggang Bai, Lin Zhou, Youping Xiao, Dechun Zheng, Kongqi Lin, Sufang Qiu, Yunbin Chen, Jianji Pan

Journal: Medicine (Baltimore). 2016 Mar;95(9):e2667.

 

The aim of the study was to evaluate whether short axis and long axis on axial and coronal magnetic resonance imaging planes would reflect the tumor burden or alteration in size after induction chemotherapy in nasopharyngeal carcinoma. Patients with pathologically confirmed nasopharyngeal ...

Last Updated: 6 Mar 2016

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Pretreatment Dynamic Contrast-Enhanced MRI Improves Prediction of Early Distant Metastases in Patients With Nasopharyngeal Carcinoma.
 

Author(s): Shy-Chyi Chin, Chien-Yu Lin, Bing-Shen Huang, Ngan-Ming Tsang, Kang-Hsing Fan, Yi-Kang Ku, Cheng-Lung Hsu, Sheng-Chieh Chan, Shiang-Fu Huang, Cheng-He Li, Hsiao-Jung Tseng, Chun-Ta Liao, Ho-Ling Liu, Kyunghyun Sung

Journal: Medicine (Baltimore). 2016 Feb;95(6):e2567.

 

The identification of early distant metastases (DM) in patients with newly diagnosed, previously untreated nasopharyngeal carcinoma (NPC) plays an important role in selecting the most appropriate treatment approach. Here, we sought to investigate the predictive value of distinct MRI ...

Last Updated: 13 Feb 2016

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Prognostic Value of Plasma Epstein-Barr Virus DNA for Local and Regionally Advanced Nasopharyngeal Carcinoma Treated With Cisplatin-Based Concurrent Chemoradiotherapy in Intensity-Modulated Radiotherapy Era.
 

Author(s): Wen-Hui Chen, Lin-Quan Tang, Shan-Shan Guo, Qiu-Yan Chen, Lu Zhang, Li-Ting Liu, Chao-Nan Qian, Xiang Guo, Dan Xie, Mu-Sheng Zeng, Hai-Qiang Mai

Journal: Medicine (Baltimore). 2016 Feb;95(5):e2642.

 

This study aimed to evaluate the prognostic value of plasma Epstein-Barr Virus DNA (EBV DNA) for local and regionally advanced nasopharyngeal carcinoma (NPC) patients treated with concurrent chemoradiotherapy in intensity-modulated radiotherapy (IMRT) era.In this observational study, ...

Last Updated: 5 Feb 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Nasopharyngeal carcinoma" returned 78 free, full-text review articles on human participants. First 3 results:

A Review: Proteomics in Nasopharyngeal Carcinoma.
 

Author(s): Ze-Tan Chen, Zhong-Guo Liang, Xiao-Dong Zhu

Journal:

 

Although radiotherapy is generally effective in the treatment of major nasopharyngeal carcinoma (NPC), this treatment still makes approximately 20% of patients radioresistant. Therefore, the identification of blood or biopsy biomarkers that can predict the treatment response to radioresistance ...

Last Updated: 18 Jul 2015

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Progresses and Challenges in Chemotherapy for Loco- Regionally Advanced Nasopharyngeal Carcinoma.
 

Author(s): Zhong-Guo Liang, Ze-Tan Chen, Ling Li, Song Qu, Xiao-Dong Zhu

Journal: Asian Pac. J. Cancer Prev.. 2015 ;16(12):4825-32.

 

Incidence rates of nasopharyngeal carcinoma are high in Indonesia, Singapore and South-Eastern China. Chemoradiotherapy has been the standard regimen for locally advanced nasopharyngeal carcinoma according to guidelines from the National Comprehensive Cancer Network. Recently, advances ...

Last Updated: 12 Jul 2015

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Omics-based identification of biomarkers for nasopharyngeal carcinoma.
 

Author(s): Tavan Janvilisri

Journal: Dis. Markers. 2015 ;2015():762128.

 

Nasopharyngeal carcinoma (NPC) is a head and neck cancer that is highly found in distinct geographic areas, such as Southeast Asia. The management of NPC remains burdensome as the prognosis is poor due to the late presentation of the disease and the complex nature of NPC pathogenesis. ...

Last Updated: 22 May 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Famitinib in Treating Patients With Recurrent and/or Metastatic Nasopharyngeal Carcinoma (NPC)
 

Status: Recruiting

Condition Summary: Recurrent Nasopharyngeal Carcinoma; Metastatic Nasopharyngeal Carcinoma

 

Last Updated: 8 Feb 2012

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Individualized Treatment in Treating Patients With Stage II-IVB Nasopharyngeal Cancer Based on EBV DNA
 

Status: Recruiting

Condition Summary: Epstein-Barr Virus Infection; Stage II Nasopharyngeal Carcinoma; Stage III Nasopharyngeal Carcinoma; Stage IVA Nasopharyngeal Carcinoma; Stage IVB Nasopharyngeal Carcinoma

 

Last Updated: 17 Jun 2016

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Nasopharyngeal Carcinoma Post IMRT
 

Status: Recruiting

Condition Summary: Nasopharyngeal Carcinoma

 

Last Updated: 5 May 2016

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