Nasopharyngeal carcinoma

Common Name(s)

Nasopharyngeal carcinoma

Nasopharyngeal carcinoma (NPC, NPCA) is a multifactorial malignancy associated with both genetic and environmental factors. The cancer arises from the epithelium of the nasopharynx. The Epstein-Barr virus has been implicated ({12:Tse et al., 2009}). A susceptibility locus for nasopharyngeal carcinoma (NPCA1) has been mapped to chromosome 4p. A second locus, NPCA2 ({161550}), has been mapped to chromosome 6p21.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Nasopharyngeal carcinoma" for support, advocacy or research.

Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

Last Updated: 29 Jul 2015

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Nasopharyngeal carcinoma" for support, advocacy or research.

Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

http://www.CancerHopeNetwork.org

Last Updated: 29 Jul 2015

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Nasopharyngeal carcinoma" returned 1229 free, full-text research articles on human participants. First 3 results:

[Clinical significance of plasma miR-24 dysregulation in nasopharyngeal carcinoma].
 

Author(s): Lu Wang, Bolong Yu, Jianhua Cen, Xinyu Peng, Youli Liu, Fangfang Zeng, Xiong Liu

Journal: Nan Fang Yi Ke Da Xue Xue Bao. 2015 May;35(5):743-7.

 

To examine the expression level of miR-24 in the plasma of nasopharyngeal carcinoma (NPC) patients and investigate the clinical significance of miR-24 in NPC development.

Last Updated: 28 May 2015

Go To URL
Expression of interleukin-8, interleukin-10 and Epstein-Barr viral-load as prognostic indicator in nasopharyngeal carcinoma.
 

Author(s): Eka Savitri, Mubarika Sofia Haryana

Journal:

 

Interleukin-8 (IL-8) is angiogeneic chemokine that plays a potential role in both development and progression of many human malignancies including nasopharyngeal carcinoma (NPC). Epstein- Barr virus (EBV) is recognized to be an important etiologic agent of NPC as the viral gene products ...

Last Updated: 7 May 2015

Go To URL
SOX1 down-regulates β-catenin and reverses malignant phenotype in nasopharyngeal carcinoma.
 

Author(s): Zhong Guan, Jialiang Zhang, Jing Wang, Hefei Wang, Feimeng Zheng, Jieren Peng, Yaodong Xu, Min Yan, Bing Liu, Bai Cui, Ying Huang, Quentin Liu

Journal:

 

Aberrant activation of the Wnt/β-catenin signaling pathway is an important factor in the development of nasopharyngeal carcinoma (NPC). Previous studies have demonstrated that the developmental gene sex-determining region Y (SRY)-box 1 (SOX1) inhibits cervical and liver tumorigenesis ...

Last Updated: 2 Feb 2015

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Nasopharyngeal carcinoma" returned 57 free, full-text review articles on human participants. First 3 results:

The role of microRNAs in nasopharyngeal carcinoma.
 

Author(s): Gongjun Tan, Xiaowei Tang, Faqing Tang

Journal: Tumour Biol.. 2015 Jan;36(1):69-79.

 

Nasopharyngeal carcinoma (NPC), a distinct type of head and neck cancer, is prevalent in Southeast Asia and southern China. Ethnic background and environmental factors contribute to the development of NPC, further complicating its pathogenesis. An increasing body of evidence indicates ...

Last Updated: 3 Feb 2015

Go To URL
Partial hepatectomy for liver metastases from nasopharyngeal carcinoma: a comparative study and review of the literature.
 

Author(s): Jun Huang, Qijiong Li, Yun Zheng, Jingxian Shen, Binkui Li, Ruhai Zou, Jianping Wang, Yunfei Yuan

Journal:

 

The management of liver metastases from nasopharyngeal carcinoma (NPC) has not been extensively investigated. This study aimed to compare the long-term outcome of patients with liver metastases from NPC who were treated by a partial hepatectomy or transcatheter hepatic artery chemoembolization ...

Last Updated: 14 Nov 2014

Go To URL
Cancer stem-like cell: a novel target for nasopharyngeal carcinoma therapy.
 

Author(s): Pingpin Wei, Man Niu, Suming Pan, Yanhong Zhou, Cijun Shuai, Jing Wang, Shuping Peng, Guiyuan Li

Journal: Stem Cell Res Ther. 2014 ;5(2):44.

 

Nasopharyngeal carcinoma (NPC) is the most common cancer originating in the nasopharynx, and is extremely common in southern regions of China. Although the standard combination of radiotherapy and chemotherapy has improved the efficiency in patients with NPC, relapse and early metastasis ...

Last Updated: 28 Aug 2014

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Famitinib in Treating Patients With Recurrent and/or Metastatic Nasopharyngeal Carcinoma (NPC)
 

Status: Recruiting

Condition Summary: Recurrent Nasopharyngeal Carcinoma; Metastatic Nasopharyngeal Carcinoma

 

Last Updated: 8 Feb 2012

Go to URL
Atorvastatin in Preventing Nasopharyngeal Carcinoma Patients Receiving Radiotherapy From Carotid Stenosis
 

Status: Recruiting

Condition Summary: Nasopharyngeal Carcinoma; Radiation Therapy Complication

 

Last Updated: 7 Feb 2014

Go to URL
Dietary Nitrate on Plasma Nitrate Levels for Nasopharyngeal Carcinoma Patients
 

Status: Recruiting

Condition Summary: Nasopharyngeal Carcinoma

 

Last Updated: 22 Jan 2014

Go to URL