Nasopharyngeal carcinoma

Common Name(s)

Nasopharyngeal carcinoma

Nasopharyngeal carcinoma (NPC, NPCA) is a multifactorial malignancy associated with both genetic and environmental factors. The cancer arises from the epithelium of the nasopharynx. The Epstein-Barr virus has been implicated ({12:Tse et al., 2009}). Genetic Heterogeneity of Susceptibility to Nasopharyngeal Carcinoma NPCA1 maps to chromosome 4p. NPCA2 ({161550}) maps to chromosome 6p21. NPCA3 ({617075}) is associated with variation in the MST1R gene ({600168}) on chromosome 3p21.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Nasopharyngeal carcinoma" for support, advocacy or research.

Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

Last Updated: 29 Jul 2015

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Nasopharyngeal carcinoma" for support, advocacy or research.

Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

http://www.CancerHopeNetwork.org

Last Updated: 29 Jul 2015

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Nasopharyngeal carcinoma" returned 1787 free, full-text research articles on human participants. First 3 results:

Prognostic Significance of Neutrophil to Lymphocyte Ratio, Lymphocyte to Monocyte Ratio, and Platelet to Lymphocyte Ratio in Patients with Nasopharyngeal Carcinoma.
 

Author(s): Aiying Lu, Haifeng Li, Yuming Zheng, Minzhong Tang, Jun Li, Huihui Wu, Weiming Zhong, Jianquan Gao, Ningjiang Ou, Yonglin Cai

Journal: Biomed Res Int. 2017 ;2017():3047802.

 

The peripheral blood neutrophil to lymphocyte ratio (NLR), lymphocyte to monocyte ratio (LMR), and platelet to lymphocyte ratio (PLR) have been reported to correlate with the prognosis of many malignancies. This study evaluated the prognostic value of pretreatment NLR, LMR, and PLR ...

Last Updated: 21 Mar 2017

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A Study of 358 Cases of Locally Advanced Nasopharyngeal Carcinoma Receiving Intensity-Modulated Radiation Therapy: Improving the Seventh Edition of the American Joint Committee on Cancer T-Staging System.
 

Author(s): Qin Zhou, Yuxiang He, Yajie Zhao, Yin Wang, Weilu Kuang, Liangfang Shen

Journal: Biomed Res Int. 2017 ;2017():1419676.

 

To evaluate the rationality and limitations of the seventh edition of the American Joint Committee on Cancer (the 7th AJCC edition) T-staging system for locally advanced nasopharyngeal carcinoma (NPC). The prognosis of 358 patients with stage T3/T4 NPC treated with intensity-modulated ...

Last Updated: 7 Mar 2017

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Pediatric nasopharyngeal carcinoma: Experience from a tertiary cancer center in India.
 

Author(s): V Radhakrishnan, P Kumar, S Totadri, P Ganesan, G Selvaluxmy, T Ganesan, M Dhanushkodi, T Sagar

Journal: Indian J Cancer. ;53(3):377-380.

 

Pediatric nasopharyngeal carcinomas (NPCs) are rare tumors. There is paucity of data on outcomes in pediatric NPC from developing countries.

Last Updated: 28 Feb 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Nasopharyngeal carcinoma" returned 93 free, full-text review articles on human participants. First 3 results:

Pretreatment hematologic markers as prognostic factors in patients with nasopharyngeal carcinoma: A systematic review and meta-analysis.
 

Author(s): Li Su, Mingwei Zhang, Weijian Zhang, Chuanshu Cai, Jinsheng Hong

Journal: Medicine (Baltimore). 2017 Mar;96(11):e6364.

 

Pretreatment hematologic parameters of the inflammatory response, including lymphocyte, neutrophil, and platelet counts, neutrophil-to-lymphocyte ratio (NLR), lymphocyte-to-monocyte ratio, and platelet-to-lymphocyte ratio, have emerged as prognostic factors for patients with cancer. ...

Last Updated: 15 Mar 2017

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Metastatic nasopharyngeal carcinoma presenting as an isolated breast mass: A diagnostic pitfall and a review of literature.
 

Author(s): Trupti Pai, Nita Nair, Gauri Pantvaidya, Kedar Deodhar, Tanuja Shet

Journal: Indian J Pathol Microbiol. ;60(1):119-121.

 

Metastases to breast are much rarer than primary breast tumors. We now present a case of 45-year-old female, who presented with an isolated breast mass. A positron emission tomography-computed tomography (PET-CT) done revealed hypermetabolic right breast nodules, soft tissue deposits, ...

Last Updated: 14 Feb 2017

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Revisiting induction chemotherapy before radiotherapy for head and neck cancer, part I: carcinoma of non-nasopharyngeal sites.
 

Author(s): Christopher H Chapman, Upendra Parvathaneni, Sue S Yom

Journal: Future Oncol. 2017 Mar;13(6):469-475.

 

Last Updated: 7 Feb 2017

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Donafenib Monotherapy for Previously Treated Metastatic Nasopharyngeal Carcinoma
 

Status: Not yet recruiting

Condition Summary: Nasopharyngeal Carcinoma

 

Last Updated: 12 Oct 2016

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TPC vs PF as Induction Chemotherapy Combined With CCRT for Stage IVa-b Nasopharyngeal Carcinoma
 

Status: Recruiting

Condition Summary: Nasopharyngeal Carcinoma

 

Last Updated: 20 Oct 2016

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Last Updated: 15 Apr 2016

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