Myositis ossificans

Common Name(s)

Myositis ossificans

Myositis ossificans is the development of bone where other muscle or other soft tissue is normally present. This bone formation is often painful and limits the range of motion in the affected area. Myositis ossificans develops due to deep muscle bruises after traumatic injury or as a result of inherited conditions. The inherited form, fibrodysplasia ossificans progressiva (FOP), is extremely rare and is caused by a specific gene mutation.

Symptoms of myositis ossifications caused by trauma include a solid bump, pain, and limited range of motion. Most bone growths develop in the arms or legs within a few weeks of injury and tend to occur in young adults or paraplegics, although anyone who experiences a deep muscle bruise may be affected. Individuals with myositis ossificans from FOP generally show symptoms before the age of 10. The symptoms become worse with age and may cause severe pain. FOP eventually causes the skeleton of the affected individual to fuse into a single bone structure.

Myositis ossificans is diagnosed using medical imaging to reveal abnormal bone growth. Treatments for myositis ossifications depend on the subtype and severity of bone formation. Minor myositis ossificans from trauma will often resolve without treatment. Medications may be used to decrease inflammation and pain. Surgery may be used in severe cases following trauma, but often worsens symptoms for individuals with FOP. There is currently no cure for FOP. If you are suffering from myositis ossificans, talk to your doctor about the most current treatment options.

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Condition Specific Organizations

Following organizations serve the condition "Myositis ossificans" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Myositis ossificans" returned 71 free, full-text research articles on human participants. First 3 results:

Myositis Ossificans of the Hip Due to Pyogenic Arthritis Caused by Campylobacter fetus Subspecies fetus.
 

Author(s): Sho Nishiguchi, Ichiro Sekine, Shun Kuroda, Morihiko Sato, Izumi Kitagawa

Journal: Intern. Med.. 2017 ;56(8):967-972.

 

A 61-year-old woman was admitted with severe hip pain causing immobility and high serum levels of inflammatory markers. The patient had a medical history of diabetes. She had been scheduled to undergo right hip replacement surgery for the treatment of osteoarthritis associated with ...

Last Updated: 19 Apr 2017

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[Circumscribed myositis ossificans of the elbow: about a case].
 

Author(s): Yassine Nhamoucha, Othmane Alaoui, Charifa Alaoui, Hicham Abdellaoui, Mohammed Tazi, Mohammed Oukhoya, Lamyae Chater, Karima Atarraf, Mounir Arroud, Abderahman Afifi

Journal:

 

Circumscribed myositis ossificans (CMO) is a heterotopic ossification of the striated muscles. Its location at the level of the elbow is rare. It occurs in young patients, often following trauma as it can also develop without experiencing any traumatic event. Its predominant location ...

Last Updated: 3 Feb 2017

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Myositis ossificans progressive: case report.
 

Author(s): Sofia Talbi, Nassira Aradoini, Iman El Mezouar, Fatima Ezzahra Abourazzak, Taoufik Harzy

Journal:

 

Myositis ossificans progressiva (MOP) is an autosomal dominant disorder. There is a progressive ectopic ossification and skeletal malformation, mainly in the connective tissue of muscle. The diagnosis is based on the clinical findings and radiological demonstration of the skeletal ...

Last Updated: 1 Nov 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Myositis ossificans" returned 2 free, full-text review articles on human participants. First 3 results:

[Myositis ossificans circumscripta, an unusual location: about a case and review of the literature].
 

Author(s): Ikram Taam, Khouloud Boussouni, Bouchaib Redouane, Touriya Amil, Rachida Saouab

Journal:

 

Myositis ossificans circumscripta (MOC) is a rare condition characterized by nontumoral heterotopic ossification of the soft tissues. This condition affects young subjects, occurring mainly after trauma. It is ubiquitous, predominantly located in girdles and limbs. We report the case ...

Last Updated: 19 Sep 2016

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Bilateral myositis ossificans of the masseter muscle after chemoradiotherapy and critical illness neuropathy--report of a rare entity and review of literature.
 

Author(s): Astrid L Kruse, Christine Dannemann, Klaus W Gr├Ątz

Journal:

 

Myositis ossificans in the head and neck is a rare heterotropic bone formation within a muscle. Besides fibrodysplasia ossificans progressiva, traumatic and neurogenic forms are described in the literature. We are presenting the case of a 35-year-old female patient with a very rare ...

Last Updated: 21 Aug 2009

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Clinical Trial Information This information is provided by ClinicalTrials.gov

The Fibrodysplasia Ossificans Progressiva (FOP) Connection Registry
 

Status: Recruiting

Condition Summary: Fibrodysplasia Ossificans Progressiva (FOP)

 

Last Updated: 15 Apr 2016

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Last Updated: 13 Jun 2017

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