Myositis

Common Name(s)

Myositis

Myositis is an inflammation of muscles. Affected individuals will have difficulty contracting their muscles because of the damage to the muscle fibers from the inflammation. The inflammation may be caused by the body attacking its own tissues (autoimmune), infection, drug side effects, or injury. After traumatic injury, myositis can occur in bruised areas. The inflammation may also be idiopathic, or without a known cause.

Common symptoms include muscle soreness, weakness, difficulty swallowing, and trouble climbing stairs. Individuals affected by myositis may have a decrease in their muscle mass (atrophy) for long periods of time. Individuals affected by the flu or other viral infections often experience myositis during their recovery. This is frequently seen in young children and manifests as severe leg pain and inability to walk properly for a few days.

Doctors can use lab tests, a physical exam, medical imaging, and blood or muscle samples to diagnose myositis. Treatment will depend on the cause of the inflammation. Myositis without a known cause may persist for long periods of time, while inflammation caused by infection or drugs will go away after the infection is cleared or the drug has been stopped. Common treatments for myositis include medication, physical therapy, and dietary supplements. If you are suffering from myositis, talk to your doctor about the most current treatment options.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Myositis" for support, advocacy or research.

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Muscular Dystrophy Association

MDA is the nonprofit health agency dedicated to curing muscular dystrophy, ALS and related diseases by funding worldwide research. The Association also provides comprehensive health care and support services, advocacy and education.

Last Updated: 15 Jul 2015

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Myositis" for support, advocacy or research.

Logo
Muscular Dystrophy Association

MDA is the nonprofit health agency dedicated to curing muscular dystrophy, ALS and related diseases by funding worldwide research. The Association also provides comprehensive health care and support services, advocacy and education.

http://www.mdausa.org

Last Updated: 15 Jul 2015

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Myositis" returned 479 free, full-text research articles on human participants. First 3 results:

Myositis ossificans occupying the thenar region: a case report.
 

Author(s): Tsutomu Akahane, Naoya Mori, Yukio Nakatsuchi

Journal:

 

Myositis ossificans is a benign, self-limiting, tumor-like lesion that usually affects the elbow and thigh; occurrence in the hand is uncommon. We report a rare case of a patient with myositis ossificans in the thenar region.

Last Updated: 12 May 2015

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Anti-PM/Scl antibodies are found in Japanese patients with various systemic autoimmune conditions besides myositis and scleroderma.
 

Author(s): Yoshinao Muro, Yuji Hosono, Kazumitsu Sugiura, Yasushi Ogawa, Tsuneyo Mimori, Masashi Akiyama

Journal:

 

Anti-PM/Scl antibodies are associated with polymyositis (PM)/systemic scleroderma (SSc) overlap syndromes and are also found in other systemic autoimmune diseases. Although anti-PM/Scl reactivity is found in 3-11% of PM or SSc patients and in approximately 25% of PM/SSc overlap patients, ...

Last Updated: 24 Apr 2015

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Significance of myositis autoantibody in patients with idiopathic interstitial lung disease.
 

Author(s): Ju Sun Song, Jiwon Hwang, Hoon-Suk Cha, Byeong-Ho Jeong, Gee Young Suh, Man Pyo Chung, Eun-Suk Kang

Journal: Yonsei Med. J.. 2015 May;56(3):676-83.

 

Some patients with interstitial lung disease (ILD) related to connective tissue disease (CTD) have a delayed diagnosis of the underlying CTD when the ILD is categorized as idiopathic. In this study, we evaluated the frequency of myositis autoantibodies in patients diagnosed with idiopathic ...

Last Updated: 3 Apr 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Myositis" returned 66 free, full-text review articles on human participants. First 3 results:

Amyloid deposits and inflammatory infiltrates in sporadic inclusion body myositis: the inflammatory egg comes before the degenerative chicken.
 

Author(s): Olivier Benveniste, Werner Stenzel, David Hilton-Jones, Marco Sandri, Olivier Boyer, Baziel G M van Engelen

Journal: Acta Neuropathol.. 2015 May;129(5):611-24.

 

Sporadic inclusion body myositis (sIBM) is the most frequently acquired myopathy in patients over 50 years of age. It is imperative that neurologists and rheumatologists recognize this disorder which may, through clinical and pathological similarities, mimic other myopathies, especially ...

Last Updated: 14 Apr 2015

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Radiation recall phenomenon presenting as myositis triggered by carboplatin plus paclitaxel and related literature review.
 

Author(s): Chi Hoon Maeng, Jun Sang Park, Seung Ah Lee, Dong Hwan Kim, Dong Hwan Yun, Seung-Don Yoo, Hee-Sang Kim, Jinmann Chon

Journal: J Cancer Res Ther. ;10(4):1093-7.

 

While most case reports to date are radiation recall dermatitis, radiation recall myositis, which is a distinct form of radiation recall phenomenon caused by carboplatin plus paclitaxel, has not been reported. We treated a 57-year-old female patient who suffered from recurrent cervical ...

Last Updated: 12 Jan 2015

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Ongoing developments in sporadic inclusion body myositis.
 

Author(s): Pedro M Machado, Mhoriam Ahmed, Stefen Brady, Qiang Gang, Estelle Healy, Jasper M Morrow, Amanda C Wallace, Liz Dewar, Gita Ramdharry, Matthew Parton, Janice L Holton, Henry Houlden, Linda Greensmith, Michael G Hanna

Journal: Curr Rheumatol Rep. 2014 Dec;16(12):477.

 

Sporadic inclusion body myositis (IBM) is an acquired muscle disorder associated with ageing, for which there is no effective treatment. Ongoing developments include: genetic studies that may provide insights regarding the pathogenesis of IBM, improved histopathological markers, the ...

Last Updated: 17 Nov 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Environmental Risk Factors for Myositis in Military Personnel
 

Status: Recruiting

Condition Summary: Dermatomyositis; Adult Polymyositis; Inclusion Body Myositis; Myositis

 

Last Updated: 29 Jan 2016

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Diagnostic Accuracy of Whole Body Magnetic Resonance Imaging in Inflammatory Myopathies
 

Status: Recruiting

Condition Summary: Myositis; Polymyositis; Dermatomyositis; Myositis, Inclusion Body

 

Last Updated: 21 Dec 2015

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MYOPROSP - a Prospective Cohort Study in Myositis
 

Status: Not yet recruiting

Condition Summary: Myositis; Idiopathic Inflammatory Myopathy

 

Last Updated: 10 Jun 2015

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