Myositis

Common Name(s)

Myositis

Myositis is an inflammation of muscles. Affected individuals will have difficulty contracting their muscles because of the damage to the muscle fibers from the inflammation. The inflammation may be caused by the body attacking its own tissues (autoimmune), infection, drug side effects, or injury. After traumatic injury, myositis can occur in bruised areas. The inflammation may also be idiopathic, or without a known cause.

Common symptoms include muscle soreness, weakness, difficulty swallowing, and trouble climbing stairs. Individuals affected by myositis may have a decrease in their muscle mass (atrophy) for long periods of time. Individuals affected by the flu or other viral infections often experience myositis during their recovery. This is frequently seen in young children and manifests as severe leg pain and inability to walk properly for a few days.

Doctors can use lab tests, a physical exam, medical imaging, and blood or muscle samples to diagnose myositis. Treatment will depend on the cause of the inflammation. Myositis without a known cause may persist for long periods of time, while inflammation caused by infection or drugs will go away after the infection is cleared or the drug has been stopped. Common treatments for myositis include medication, physical therapy, and dietary supplements. If you are suffering from myositis, talk to your doctor about the most current treatment options.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Myositis" for support, advocacy or research.

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Ben's Friends

Our mission is to ensure that everyone in the world with a rare disease has a safe place to go and connect with others like them.

Last Updated: 11 Jul 2016

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Muscular Dystrophy Association

MDA is the nonprofit health agency dedicated to curing muscular dystrophy, ALS and related diseases by funding worldwide research. The Association also provides comprehensive health care and support services, advocacy and education.

Last Updated: 15 Jul 2015

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Myositis" for support, advocacy or research.

Logo
Ben's Friends

Our mission is to ensure that everyone in the world with a rare disease has a safe place to go and connect with others like them.

http://www.bensfriends.org

Last Updated: 11 Jul 2016

View Details
Logo
Muscular Dystrophy Association

MDA is the nonprofit health agency dedicated to curing muscular dystrophy, ALS and related diseases by funding worldwide research. The Association also provides comprehensive health care and support services, advocacy and education.

http://www.mdausa.org

Last Updated: 15 Jul 2015

View Details

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Myositis" returned 448 free, full-text research articles on human participants. First 3 results:

[Circumscribed myositis ossificans of the elbow: about a case].
 

Author(s): Yassine Nhamoucha, Othmane Alaoui, Charifa Alaoui, Hicham Abdellaoui, Mohammed Tazi, Mohammed Oukhoya, Lamyae Chater, Karima Atarraf, Mounir Arroud, Abderahman Afifi

Journal:

 

Circumscribed myositis ossificans (CMO) is a heterotopic ossification of the striated muscles. Its location at the level of the elbow is rare. It occurs in young patients, often following trauma as it can also develop without experiencing any traumatic event. Its predominant location ...

Last Updated: 3 Feb 2017

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Atorvastatin-induced necrotizing autoimmune myositis: An emerging dominant entity in patients with autoimmune myositis presenting with a pure polymyositis phenotype.
 

Author(s): Yves Troyanov, Océane Landon-Cardinal, Marvin J Fritzler, José Ferreira, Ira N Targoff, Eric Rich, Michelle Goulet, Jean-Richard Goulet, Josiane Bourré-Tessier, Yves Robitaille, Julie Drouin, Alexandra Albert, Jean-Luc Senécal

Journal: Medicine (Baltimore). 2017 Jan;96(3):e5694.

 

The general aim of this study was to evaluate the disease spectrum in patients presenting with a pure polymyositis (pPM) phenotype. Specific objectives were to characterize clinical features, autoantibodies (aAbs), and membrane attack complex (MAC) in muscle biopsies of patients with ...

Last Updated: 18 Jan 2017

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Sporadic Inclusion Body Myositis Manifesting as Isolated Muscle Weakness of the Finger Flexors Three Years after Disease Onset.
 

Author(s): Yuichi Suwa, Naoki Suzuki, Temma Soga, Ryuhei Harada, Aya Shibui, Hiroshi Kuroda, Rumiko Izumi, Maki Tateyama, Ichiro Nakashima, Masahiro Sonoo, Masashi Aoki

Journal: Intern. Med.. ;55(23):3521-3524.

 

Sporadic inclusion body myositis (sIBM) is a chronic progressive myopathy characterized by muscle weakness of both the quadriceps femoris and finger flexors. We herein present the case of a typical male patient with sIBM, which manifested as the isolated weakness of the finger flexors ...

Last Updated: 1 Dec 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Myositis" returned 62 free, full-text review articles on human participants. First 3 results:

Haycocknema perplexum: an emerging cause of parasitic myositis in Australia.
 

Author(s): Luke J Vos, Thomas Robertson, Enzo Binotto

Journal:

 

Haycocknema perplexum is a rare cause of parasitic myositis, with all cases of human infection reported from Australia. This case involved an 80-year-old Queensland wildlife carer, who presented with muscle weakness, mild eosinophilia and creatine kinase elevation. This case supports ...

Last Updated: 3 Jan 2017

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[Myositis ossificans circumscripta, an unusual location: about a case and review of the literature].
 

Author(s): Ikram Taam, Khouloud Boussouni, Bouchaib Redouane, Touriya Amil, Rachida Saouab

Journal:

 

Myositis ossificans circumscripta (MOC) is a rare condition characterized by nontumoral heterotopic ossification of the soft tissues. This condition affects young subjects, occurring mainly after trauma. It is ubiquitous, predominantly located in girdles and limbs. We report the case ...

Last Updated: 19 Sep 2016

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Life-Threatening Hypercalcemia Revealing Diffuse and Isolated Acute Sarcoid-Like Myositis: A New Entity? (A Case-Series).
 

Author(s): Arthur Mageau, Aude Rigolet, Khadija Benali, Maria Chauchard, Salima Ladjeroud, Isabelle Mahe, Thierry Maisonobe, Marie-Paule Chauveheid, Thomas Papo, Karim Sacre

Journal: Medicine (Baltimore). 2016 Mar;95(10):e3089.

 

Up to 50% patients with sarcoidosis display extra-pulmonary disease. However, initial and isolated (ie, without lung disease) acute muscular involvement associated with pseudo-malignant hypercalcemia is very uncommon. We report on 3 cases of life-threatening hypercalcemia revealing ...

Last Updated: 11 Mar 2016

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Belimumab in Myositis
 

Status: Recruiting

Condition Summary: Myositis

 

Last Updated: 3 Aug 2016

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Study of Arimoclomol in Inclusion Body Myositis (IBM)
 

Status: Not yet recruiting

Condition Summary: Inclusion Body Myositis

 

Last Updated: 24 Apr 2017

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MYOPROSP - a Prospective Cohort Study in Myositis
 

Status: Recruiting

Condition Summary: Myositis; Idiopathic Inflammatory Myopathy

 

Last Updated: 31 Jan 2017

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