Myeloperoxidase deficiency

Common Name(s)

Myeloperoxidase deficiency

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Myeloperoxidase deficiency" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Myeloperoxidase deficiency" returned 25 free, full-text research articles on human participants. First 3 results:

Case report of myeloperoxidase deficiency associated with disseminated paracoccidioidomycosis and peritoneal tuberculosis.
 

Author(s): Maurício Domingues-Ferreira, Ariel Levy, Noac Chuffi Barros, Dalton Luis Bertolini, Dewton de Moraes Vasconcelos

Journal: Rev. Soc. Bras. Med. Trop.. ;50(4):568-570.

 

Myeloperoxidase (MOP) is present in monocyte and neutrophil lysosomes, catalyzing hydrogen peroxide and chloride ion conversion to hypochlorous acid. MOP seems to destroy pathogens during phagocytosis by neutrophils and is considered an important defense against innumerous bacteria. ...

Last Updated: 31 Dec 1969

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Homozygous calreticulin mutations in patients with myelofibrosis lead to acquired myeloperoxidase deficiency.
 

Author(s): Alexandre P A Theocharides, Pontus Lundberg, Asvin K K Lakkaraju, Veronika Lysenko, Renier Myburgh, Adriano Aguzzi, Radek C Skoda, Markus G Manz

Journal: Blood. 2016 Jun;127(25):3253-9.

 

The pathogenesis of acquired myeloperoxidase (MPO) deficiency, a rare phenomenon observed in patients with Philadelphia chromosome-negative myeloproliferative neoplasms (MPNs), is unknown. MPO is a glycoprotein (GP) chaperoned by calreticulin (CALR) in the endoplasmic reticulum. Mutations ...

Last Updated: 31 Dec 1969

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Myeloperoxidase deficiency preserves vasomotor function in humans.
 

Author(s): Tanja K Rudolph, Sabine Wipper, Beate Reiter, Volker Rudolph, Anja Coym, Christian Detter, Denise Lau, Anna Klinke, Kai Friedrichs, Thomas Rau, Michaela Pekarova, Detlef Russ, Kay Knöll, Mandy Kolk, Bernd Schroeder, Karl Wegscheider, Hilke Andresen, Edzard Schwedhelm, Rainer Boeger, Heimo Ehmke, Stephan Baldus

Journal: Eur. Heart J.. 2012 Jul;33(13):1625-34.

 

Observational studies have suggested a mechanistic link between the leucocyte-derived enzyme myeloperoxidase (MPO) and vasomotor function. Here, we tested whether MPO is systemically affecting vascular tone in humans.

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Myeloperoxidase deficiency" returned 0 free, full-text review articles on human participants.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.