Mycosis fungoides

Common Name(s)

Mycosis fungoides

Mycosis fungoides is a disease in which T-cell lymphocytes (a type of white blood cell) become malignant (cancerous) and affect the skin. This condition is one of the most common types of T-cell lymphoma. Mycosis fungoides is characterized by a scaly, red rash that develops on the skin, particularly on areas that are not usually exposed to the sun. The rash may last for months or years without causing any symptoms. Over time, a thin, reddened, eczema-like rash may develop, followed by thickened, red patches of skin. Finally, tumors form which may develop into ulcers and become infected. Mycosis fungoides is difficult to cure. Treatment is usually palliative, with the intention of relieving symptoms and improving the quality of life.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Mycosis fungoides" for support, advocacy or research.

Cutaneous Lymphoma Foundation

The Cutaneous Lymphoma Foundation is an independent, nonprofit patient advocacy organization whose mission is supporting every person with cutaneous lymphoma by promoting awareness and education, advancing patient care and facilitating research.

Last Updated: 6 Jan 2013

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Mycosis fungoides" for support, advocacy or research.

Cutaneous Lymphoma Foundation

The Cutaneous Lymphoma Foundation is an independent, nonprofit patient advocacy organization whose mission is supporting every person with cutaneous lymphoma by promoting awareness and education, advancing patient care and facilitating research.

http://www.clfoundation.org

Last Updated: 6 Jan 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Mycosis fungoides" returned 409 free, full-text research articles on human participants. First 3 results:

Expression of SOX18 in Mycosis Fungoides.
 

Author(s): Alina Jankowska-Konsur, Christopher Kobierzycki, Adam Reich, Aleksandra Piotrowska, Agnieszka Gomulkiewicz, Mateusz Olbromski, Marzena Podhorska-Okołów, Piotr Dzięgiel, Jacek C Szepietowski

Journal: Acta Derm. Venereol.. 2017 Jan;96(7):17-23.

 

SOX18 is a transcription factor involved in the development of hair follicle, blood and lymphatic vessels, as well as regenerative processes. In addition, accumulated data indicate the role of SOX18 in tumourigenesis. So far, no studies on the role of SOX18 expression in mycosis fungoides ...

Last Updated: 27 May 2016

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Pancreatic metastasis from mycosis fungoides mimicking primary pancreatic tumor.
 

Author(s): Paola Ceriolo, Valentina Fausti, Elisa Cinotti, Silvia Bonadio, Lizzia Raffaghello, Giovanna Bianchi, Giulio Fraternali Orcioni, Roberto Fiocca, Franco Rongioletti, Vito Pistoia, Giacomo Borgonovo

Journal: World J. Gastroenterol.. 2016 Mar;22(12):3496-501.

 

Mycosis fungoides (MF) is a cutaneous T-cell lymphoma that can undergo local progression with possible systemic dissemination. We report a case of a patient affected by MF with a pancreatic mass that was a diagnostic challenge between primitive tumor and pancreatic metastasis from ...

Last Updated: 29 Mar 2016

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Analysis of differential β variable region of T cell receptor expression and NAV3/TNFRSF1B gene mutation in mycosis fungoides.
 

Author(s): Hongzhou Cui, Jie Liu, Li Li, Jingyu Ren, Shuping Guo, Li Bai

Journal: Oncotarget. 2016 Apr;7(14):17986-90.

 

This study aimed to analyze the predominant expression of the variable region of T cell receptor (TRBV) and determine whether NAV3 or TNFRSF1B gene mutation involved in the pathogenesis of MF.

Last Updated: 14 Jul 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Mycosis fungoides" returned 37 free, full-text review articles on human participants. First 3 results:

Mycosis fungoides patient accompanied actinic keratosis, actinic keratosis with squamous cell carcinoma transformation, and porokeratosis after NBUVB therapy - 1st case report and review of the literature.
 

Author(s): Meng-Jie Zhao, Bilal Abdul-Fattah, Xiao-Ying Qu, Cui-Yan Wang, Xia Wang, Yi Ran, Ting Lai, Si-Yuan Chen, Chang-Zheng Huang

Journal: Medicine (Baltimore). 2016 Oct;95(41):e5043.

 

Mycosis fungoides (MF) is the most common form of primary cutaneous T cell lymphoma. Narrowband ultraviolet B light (NBUVB) is used increasingly in treating MF because of its good toleration and well-established management.

Last Updated: 14 Oct 2016

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Romidepsin for the treatment of relapsed/refractory cutaneous T-cell lymphoma (mycosis fungoides/Sézary syndrome): Use in a community setting.
 

Author(s): Sunil A Reddy

Journal: Crit. Rev. Oncol. Hematol.. 2016 Oct;106():99-107.

 

Cutaneous T-cell lymphoma (CTCL) is a heterogeneous group of rare non-Hodgkin lymphomas that arise in the skin. In advanced stages, CTCL becomes systemic and is associated with poor prognosis. Diagnosis of CTCL and treatment of early-stage disease with topical therapies often occurs ...

Last Updated: 17 Sep 2016

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Hematopoietic Stem Cell Transplant for Mycosis Fungoides and Sézary Syndrome.
 

Author(s): Pooja Virmani, Jasmine Zain, Steven T Rosen, Patricia L Myskowski, Christiane Querfeld

Journal: Dermatol Clin. 2015 Oct;33(4):807-18.

 

Mycosis fungoides (MF) and Sézary syndrome (SS) are common types of primary cutaneous T-cell lymphoma. Early-stage MF has a favorable prognosis and responds well to skin-directed regimens. Patients with advanced-stage MF, transformed MF, and SS are treated with combined systemic ...

Last Updated: 5 Oct 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Safety and Effectiveness of A-dmDT390-bisFv(UCHT1) Fusion Protein in Subjects With Mycosis Fungoides
 

Status: Not yet recruiting

Condition Summary: Mycosis Fungoides

 

Last Updated: 21 Oct 2016

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Stem Cell Transplant Therapy With Campath-1H for Treating Advanced Mycosis Fungoides and Sezary Syndrome
 

Status: Recruiting

Condition Summary: Mycosis Fungoides; Sezary Syndrome

 

Last Updated: 24 Jan 2017

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