Mycosis fungoides

Common Name(s)

Mycosis fungoides

Mycosis fungoides is a disease in which T-cell lymphocytes (a type of white blood cell) become malignant (cancerous) and affect the skin. This condition is one of the most common types of T-cell lymphoma. Mycosis fungoides is characterized by a scaly, red rash that develops on the skin, particularly on areas that are not usually exposed to the sun. The rash may last for months or years without causing any symptoms. Over time, a thin, reddened, eczema-like rash may develop, followed by thickened, red patches of skin. Finally, tumors form which may develop into ulcers and become infected. Mycosis fungoides is difficult to cure. Treatment is usually palliative, with the intention of relieving symptoms and improving the quality of life.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Mycosis fungoides" for support, advocacy or research.

Cutaneous Lymphoma Foundation

The Cutaneous Lymphoma Foundation is an independent, nonprofit patient advocacy organization whose mission is supporting every person with cutaneous lymphoma by promoting awareness and education, advancing patient care and facilitating research.

Last Updated: 6 Jan 2013

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Mycosis fungoides" for support, advocacy or research.

Cutaneous Lymphoma Foundation

The Cutaneous Lymphoma Foundation is an independent, nonprofit patient advocacy organization whose mission is supporting every person with cutaneous lymphoma by promoting awareness and education, advancing patient care and facilitating research.

http://www.clfoundation.org

Last Updated: 6 Jan 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Mycosis fungoides" returned 330 free, full-text research articles on human participants. First 3 results:

T-cell clonality assessment by next-generation sequencing improves detection sensitivity in mycosis fungoides.
 

Author(s): Kari E Sufficool, Christina M Lockwood, Haley J Abel, Ian S Hagemann, Jonathan A Schumacher, Todd W Kelley, Eric J Duncavage

Journal: J. Am. Acad. Dermatol.. 2015 Aug;73(2):228-36.e2.

 

T-cell receptor (TCR) clonality assessment is a principal diagnostic test in the management of mycosis fungoides (MF). However, current polymerase chain reaction-based methods may produce ambiguous results, often because of low abundance of clonal T lymphocytes, resulting in weak ...

Last Updated: 18 Jul 2015

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Evaluation of cardiovascular disease risk factors in patients with mycosis fungoides.
 

Author(s): Fatma Pelin Cengiz, Nazan Emiroglu

Journal: An Bras Dermatol. ;90(1):36-40.

 

Mycosis fungoides, the most common subtype of cutaneous T-cell lymphoma, is more common in patients aged 45-55.

Last Updated: 12 Feb 2015

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Pagetoid reticulosis Woringer-Kolopp type, a particular variant of mycosis fungoides: a case report.
 

Author(s): Silviu Horia Morariu, Maria Rotaru, Mihai Dorin Vartolomei, Mihai Turcu, Andreea Luciana Chiotoroiu, Mircea Suciu, Ovidiu Simion Cotoi

Journal: Rom J Morphol Embryol. 2014 ;55(4):1469-72.

 

According to the definition of WHO, pagetoid reticulosis (PR) is characterized by the presence of unique skin lesion in the shape of patches or plaques caused by the proliferation of atypical T-cells in epidermis. We report the case of a 50-year-old female, presenting a 50×65 mm ...

Last Updated: 23 Jan 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Mycosis fungoides" returned 30 free, full-text review articles on human participants. First 3 results:

Phototherapy for mycosis fungoides.
 

Author(s): Sunil Dogra, Rahul Mahajan

Journal: Indian J Dermatol Venereol Leprol. ;81(2):124-35.

 

Both phototherapy and photochemotherapy have been used in all stages of mycosis fungoides since they improve the symptoms and have a favourable adverse effect profile.

Last Updated: 10 Mar 2015

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New and established treatment options for mycosis fungoides and Sézary syndrome - an update.
 

Author(s): Susanne Dugas-Breit, Hans-Joachim Schulze, Christian Hallermann

Journal: J Dtsch Dermatol Ges. 2014 Jul;12(7):561-9.

 

At the time of diagnosis primary cutaneous lymphomas are limited to the skin. T-cell lymphomas represent at least two thirds of all primary cutaneous lymphomas with mycosis fungoides and Sézary syndrome being the most frequent entities. A precise staging based on clinical, histological, ...

Last Updated: 1 Jul 2014

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A review of survival in mycosis fungoides.
 

Author(s): Robin T Vollmer

Journal: Am. J. Clin. Pathol.. 2014 May;141(5):706-11.

 

The objectives of this study are to review prior publications of survival for patients with mycosis fungoides (MF), to perform some analyses on the consolidated data, and then to consider the implications of the results.

Last Updated: 9 Apr 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Study of Alemtuzumab to Treat Advanced Mycosis Fungoides/Sezary Syndrome
 

Status: Recruiting

Condition Summary: Mycosis Fungoides; Sezary Syndrome

 

Last Updated: 2 Apr 2007

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Stem Cell Transplant Therapy With Campath-1H for Treating Advanced Mycosis Fungoides and Sezary Syndrome
 

Status: Recruiting

Condition Summary: Mycosis Fungoides; Sezary Syndrome

 

Last Updated: 10 Dec 2015

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SGN-35 in CD30-positive Lymphoproliferative Disorders (ALCL), Mycosis Fungoides (MF), and Extensive Lymphomatoid Papulosis (LyP)
 

Status: Recruiting

Condition Summary: CD-30 Positive Anaplastic Large T-cell Cutaneous Lymphoma; Lymphoma, Primary Cutaneous Anaplastic Large Cell; Lymphomatoid Papulosis; Mycosis Fungoides; Skin Lymphoma; Cutaneous Lymphomas; Lymphoma; Hematologic Disorder

 

Last Updated: 28 Dec 2015

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