Mycobacterium Avium Complex

Common Name(s)

Mycobacterium Avium Complex

Mycobacterium avium complex (MAC) is a type of bacteria that can cause disease by infecting humans with weakened immune systems (the system in the body which helps to fight off various infections). HIV/AIDS is a common cause of a weakened immune system that may predispose someone to MAC infection. MAC is found in food, soil, water, and is usually harmless to people with healthy immune systems. Symptoms include fever, abdominal pain, fatigue, diarrhea, and low blood counts (anemia). Since the MAC bacteria are in contact with humans so often, it is hard to prevent exposure; however, there are available preventative medications for people with weakened immune systems.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Mycobacterium Avium Complex" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Mycobacterium Avium Complex" returned 306 free, full-text research articles on human participants. First 3 results:

Development and validation of a prognostic scoring model for Mycobacterium avium complex lung disease: an observational cohort study.
 

Author(s): Shogo Kumagai, Akihiro Ito, Toru Hashimoto, Satoshi Marumo, Hironobu Tokumasu, Aya Kotani, Haruka Yamaki, Masahiro Shirata, Koji Furuuchi, Motonari Fukui, Tadashi Ishida

Journal:

 

Patients with Mycobacterium avium complex (MAC) lung disease (LD) have a heterogeneous prognosis. This study aimed to develop and validate a prognostic scoring model for these patients using independent risk factors for survival.

Last Updated: 20 Jun 2017

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Minimum inhibitory concentration distributions for Mycobacterium avium complex-towards evidence-based susceptibility breakpoints.
 

Author(s): Thomas Schön, Erja Chryssanthou

Journal: Int. J. Infect. Dis.. 2017 Feb;55():122-124.

 

Patients with clinical infections caused by the Mycobacterium avium complex (MAC) are treated for at least 1 year following sputum conversion with a regimen that suffers from a suboptimal cure rate. The correlation between clinical outcome and drug susceptibility testing breakpoints ...

Last Updated: 10 Jan 2017

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Levels of Antibody against Glycopeptidolipid Core as a Marker for Monitoring Treatment Response in Mycobacterium avium Complex Pulmonary Disease: a Prospective Cohort Study.
 

Author(s): Seigo Kitada, Ryoji Maekura, Kenji Yoshimura, Keisuke Miki, Mari Miki, Yohei Oshitani, Kohei Nishida, Nobuhiko Sawa, Masahide Mori, Kazuo Kobayashi

Journal: J. Clin. Microbiol.. 2017 Mar;55(3):884-892.

 

The diagnosis of Mycobacterium avium complex pulmonary disease (MAC-PD) is sometimes complicated and time-consuming. A serodiagnostic kit that measures the serum levels of IgA antibodies against the glycopeptidolipid (GPL) core is commercially available and has good diagnostic accuracy ...

Last Updated: 29 Dec 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Mycobacterium Avium Complex" returned 15 free, full-text review articles on human participants. First 3 results:

Serodiagnosis of Mycobacterium avium complex disease in humans: translational research from basic mycobacteriology to clinical medicine.
 

Author(s): Kazuo Kobayashi

Journal: Jpn. J. Infect. Dis.. 2014 ;67(5):329-32.

 

Rapid and accurate diagnosis of infectious diseases, including mycobacterial disease such as tuberculosis (TB) and diseases due to nontuberculous mycobacteria (NTM), is a very important element of global health. The gold standard in diagnosis of mycobacterial diseases remains clinical ...

Last Updated: 22 Sep 2014

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Trends in overall opportunistic illnesses, Pneumocystis carinii pneumonia, cerebral toxoplasmosis and Mycobacterium avium complex incidence rates over the 30 years of the HIV epidemic: a systematic review.
 

Author(s): Lara Coelho, Valdiléa Gonçalves Veloso, Beatriz Grinsztejn, Paula Mendes Luz

Journal: Braz J Infect Dis. ;18(2):196-210.

 

The natural history of HIV infection has changed dramatically after the introduction of highly active antiretroviral therapy. Currently, opportunistic illnesses still represent a major cause of death and hospitalization in this population. In this study, we review the trends in opportunistic ...

Last Updated: 18 Mar 2014

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Mycobacterium avium complex--the role of potable water in disease transmission.
 

Author(s): H Whiley, A Keegan, S Giglio, R Bentham

Journal: J. Appl. Microbiol.. 2012 Aug;113(2):223-32.

 

Mycobacterium avium complex (MAC) is a group of opportunistic pathogens of major public health concern. It is responsible for a wide spectrum of disease dependent on subspecies, route of infection and patients pre-existing conditions. Presently, there is limited research on the incidence ...

Last Updated: 18 Jul 2012

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Clofazimine in the Treatment of Pulmonary Mycobacterium Avium Complex (MAC)
 

Status: Recruiting

Condition Summary: Mycobacterium Avium Complex

 

Last Updated: 19 Sep 2017

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CLArithromycin Versus AZIthromycin in the Treatment of Mycobacterium Avium Complex (MAC) Lung Infections
 

Status: Not yet recruiting

Condition Summary: Lung Infection; Mycobacterium Avium Complex

 

Last Updated: 1 Aug 2017

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Application of MACS and Time-lapse Technology in Good-prognosis Patients
 

Status: Recruiting

Condition Summary: MACS Technique Efficacy

 

Last Updated: 4 Aug 2016

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