Mycobacterium Avium Complex

Common Name(s)

Mycobacterium Avium Complex

Mycobacterium avium complex (MAC) is a type of bacteria that can cause disease by infecting humans with weakened immune systems (the system in the body which helps to fight off various infections). HIV/AIDS is a common cause of a weakened immune system that may predispose someone to MAC infection. MAC is found in food, soil, water, and is usually harmless to people with healthy immune systems. Symptoms include fever, abdominal pain, fatigue, diarrhea, and low blood counts (anemia). Since the MAC bacteria are in contact with humans so often, it is hard to prevent exposure; however, there are available preventative medications for people with weakened immune systems.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Mycobacterium Avium Complex" for support, advocacy or research.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Mycobacterium Avium Complex" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Mycobacterium Avium Complex" returned 381 free, full-text research articles on human participants. First 3 results:

High recurrence rate supports need for secondary prophylaxis in non-HIV patients with disseminated mycobacterium avium complex infection: a multi-center observational study.
 

Author(s): Siddharth Sridhar, Kitty S C Fung, Jasper F W Chan, Jimmy Y W Lam, Eric K T Yip, Ivan F N Hung, Alan K L Wu, Tak-Lun Que, Susanna K P Lau, Patrick C Y Woo

Journal:

 

Long-term outcomes in non-HIV immunocompromised patients with disseminated Mycobacterium avium complex (dMAC) infections are unknown and the need for post-treatment secondary prophylaxis against MAC is uncertain in this setting. The objective of this study was to determine the need ...

Last Updated: 10 Feb 2016

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Analysis of drug treatment outcome in clarithromycin-resistant Mycobacterium avium complex lung disease.
 

Author(s): Tsukasa Kadota, Hirotoshi Matsui, Takashi Hirose, Junko Suzuki, Minako Saito, Tomohiro Akaba, Kouichi Kobayashi, Shunsuke Akashi, Masahiro Kawashima, Atsuhisa Tamura, Hideaki Nagai, Shinobu Akagawa, Nobuyuki Kobayashi, Ken Ohta

Journal:

 

Although the isolation of clarithromycin (CAM)-resistant Mycobacterium avium complex (MAC) indicates a poor treatment outcome and increased mortality, there have been only a few reports on drug treatment for CAM-resistant MAC lung disease. We aimed to reveal the effectiveness of the ...

Last Updated: 28 Jan 2016

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Health-related quality of life is inversely correlated with C-reactive protein and age in Mycobacterium avium complex lung disease: a cross-sectional analysis of 235 patients.
 

Author(s): Takanori Asakura, Yohei Funatsu, Makoto Ishii, Ho Namkoong, Kazuma Yagi, Shoji Suzuki, Takahiro Asami, Tetsuro Kamo, Hiroshi Fujiwara, Yoshifumi Uwamino, Tomoyasu Nishimura, Sadatomo Tasaka, Tomoko Betsuyaku, Naoki Hasegawa

Journal:

 

Mycobacterium avium complex (MAC) lung diseases generally cause chronic disease in immunocompetent hosts. Although a few studies have examined health-related quality of life (HRQL) in patients with MAC lung disease, there have been no large studies. This study aimed to evaluate HRQL ...

Last Updated: 4 Dec 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Mycobacterium Avium Complex" returned 22 free, full-text review articles on human participants. First 3 results:

Serodiagnosis of Mycobacterium avium complex disease in humans: translational research from basic mycobacteriology to clinical medicine.
 

Author(s): Kazuo Kobayashi

Journal: Jpn. J. Infect. Dis.. 2014 ;67(5):329-32.

 

Rapid and accurate diagnosis of infectious diseases, including mycobacterial disease such as tuberculosis (TB) and diseases due to nontuberculous mycobacteria (NTM), is a very important element of global health. The gold standard in diagnosis of mycobacterial diseases remains clinical ...

Last Updated: 22 Sep 2014

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Trends in overall opportunistic illnesses, Pneumocystis carinii pneumonia, cerebral toxoplasmosis and Mycobacterium avium complex incidence rates over the 30 years of the HIV epidemic: a systematic review.
 

Author(s): Lara Coelho, Valdiléa Gonçalves Veloso, Beatriz Grinsztejn, Paula Mendes Luz

Journal: Braz J Infect Dis. ;18(2):196-210.

 

The natural history of HIV infection has changed dramatically after the introduction of highly active antiretroviral therapy. Currently, opportunistic illnesses still represent a major cause of death and hospitalization in this population. In this study, we review the trends in opportunistic ...

Last Updated: 18 Mar 2014

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Mycobacterium avium complex--the role of potable water in disease transmission.
 

Author(s): H Whiley, A Keegan, S Giglio, R Bentham

Journal: J. Appl. Microbiol.. 2012 Aug;113(2):223-32.

 

Mycobacterium avium complex (MAC) is a group of opportunistic pathogens of major public health concern. It is responsible for a wide spectrum of disease dependent on subspecies, route of infection and patients pre-existing conditions. Presently, there is limited research on the incidence ...

Last Updated: 18 Jul 2012

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Program Cell Death Receptor 1 in Mycobacterium Avium Complex Lung Disease
 

Status: Recruiting

Condition Summary: Mycobacterium Avium

 

Last Updated: 19 May 2016

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Application of MACS and Time-lapse Technology in Good-prognosis Patients
 

Status: Recruiting

Condition Summary: MACS Technique Efficacy

 

Last Updated: 4 Aug 2016

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The Role of Inflammasome in Inflammatory Macrophage in Mycobacterium Avium Complex-lung Disease and Mycobacterium Abscessus-lung Disease
 

Status: Recruiting

Condition Summary: To Investigate the Inflammasome Response of Inflammatory and Resting Macrophage; To Compare the Difference of Inflammasome Response of Inflammatory Macrophage; To Study the Diagnostic Aid From Immunological Markers in Inflammasome Response

 

Last Updated: 27 Jun 2014

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