Mycobacterium Avium Complex

Common Name(s)

Mycobacterium Avium Complex

Mycobacterium avium complex (MAC) is a type of bacteria that can cause disease by infecting humans with weakened immune systems (the system in the body which helps to fight off various infections). HIV/AIDS is a common cause of a weakened immune system that may predispose someone to MAC infection. MAC is found in food, soil, water, and is usually harmless to people with healthy immune systems. Symptoms include fever, abdominal pain, fatigue, diarrhea, and low blood counts (anemia). Since the MAC bacteria are in contact with humans so often, it is hard to prevent exposure; however, there are available preventative medications for people with weakened immune systems.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Mycobacterium Avium Complex" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Mycobacterium Avium Complex" returned 343 free, full-text research articles on human participants. First 3 results:

Proposed definitions for epidemiologic and clinical studies of Mycobacterium avium complex pulmonary disease.
 

Author(s): Rachel N Plotinsky, Elizabeth A Talbot, C Fordham von Reyn

Journal:

 

Epidemiologic and clinical studies of Mycobacterium avium complex (MAC) pulmonary disease typically use strict ATS/IDSA definitions designed for decisions about treatment. Studies based on these criteria may exclude a substantial number of patients with true disease. We reviewed patients ...

Last Updated: 22 Nov 2013

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Sero-diagnosis of Mycobacterium avium complex lung disease using serum immunoglobulin A antibody against glycopeptidolipid antigen in Taiwan.
 

Author(s): Chin-Chung Shu, Manabu Ato, Jann-Tay Wang, Ruwen Jou, Jann-Yuan Wang, Kazuo Kobayashi, Hsin-Chih Lai, Chong-Jen Yu, Li-Na Lee, Kwen-Tay Luh

Journal:

 

Lung disease (LD) due to non-tuberculous mycobacteria is an important clinical concern. Mycobacterium avium complex (MAC) is one of the most common causative agents but the diagnosis of MAC-LD remains challenging. Detection of serum IgA antibody against MAC glycopeptidolipid (GPL) ...

Last Updated: 22 Nov 2013

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Virulence and immune response induced by Mycobacterium avium complex strains in a model of progressive pulmonary tuberculosis and subcutaneous infection in BALB/c mice.
 

Author(s): Mónica González-Pérez, Leonardo Mariño-Ramírez, Carlos Alberto Parra-López, Martha Isabel Murcia, Brenda Marquina, Dulce Mata-Espinoza, Yadira Rodriguez-Míguez, Guillermina J Baay-Guzman, Sara Huerta-Yepez, Rogelio Hernandez-Pando

Journal: Infect. Immun.. 2013 Nov;81(11):4001-12.

 

The genus Mycobacterium comprises more than 150 species, including important pathogens for humans which cause major public health problems. The vast majority of efforts to understand the genus have been addressed in studies with Mycobacterium tuberculosis. The biological differentiation ...

Last Updated: 11 Oct 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Mycobacterium Avium Complex" returned 19 free, full-text review articles on human participants. First 3 results:

Trends in overall opportunistic illnesses, Pneumocystis carinii pneumonia, cerebral toxoplasmosis and Mycobacterium avium complex incidence rates over the 30 years of the HIV epidemic: a systematic review.
 

Author(s): Lara Coelho, Valdiléa Gonçalves Veloso, Beatriz Grinsztejn, Paula Mendes Luz

Journal: Braz J Infect Dis. ;18(2):196-210.

 

The natural history of HIV infection has changed dramatically after the introduction of highly active antiretroviral therapy. Currently, opportunistic illnesses still represent a major cause of death and hospitalization in this population. In this study, we review the trends in opportunistic ...

Last Updated: 18 Mar 2014

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Peritonitis due to Mycobacterium avium complex in patients with AIDS: report of five cases and review of the literature.
 

Author(s): Un-In Wu, Mao-Yuan Chen, Ruey-Heng Hu, Szu-Min Hsieh, Wang-Huei Sheng, Yi-Chun Lo, Chien-Ching Hung, Shan-Chwen Chang

Journal: Int. J. Infect. Dis.. 2009 Mar;13(2):285-90.

 

Mycobacterium avium complex (MAC) often causes disseminated infection in patients at an advanced stage of HIV infection; however, peritonitis associated with disseminated MAC infection is rare.

Last Updated: 3 Mar 2009

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Clinical and immunologic features of an atypical intracranial mycobacterium avium complex (MAC) infection compared with those of pulmonary MAC infections.
 

Author(s): Mouhannad Sadek, Feng Yun Yue, Erika Yue Lee, Gabor Gyenes, R Brad Jones, Victor Hoffstein, David G Munoz, Ignatius Fong, Mario Ostrowski

Journal: Clin. Vaccine Immunol.. 2008 Oct;15(10):1580-9.

 

Members of the Mycobacterium avium complex (MAC) may cause chronic pulmonary infections in otherwise healthy elderly persons but rarely invade parts of the body outside of the lungs in immunocompetent hosts. We present a case of an isolated intracranial MAC infection in an apparently ...

Last Updated: 7 Oct 2008

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Application of MACS and Time-lapse Technology in Good-prognosis Patients
 

Status: Recruiting

Condition Summary: MACS Technique Efficacy

 

Last Updated: 13 Mar 2014

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The Role of Inflammasome in Inflammatory Macrophage in Mycobacterium Avium Complex-lung Disease and Mycobacterium Abscessus-lung Disease
 

Status: Recruiting

Condition Summary: To Investigate the Inflammasome Response of Inflammatory and Resting Macrophage; To Compare the Difference of Inflammasome Response of Inflammatory Macrophage; To Study the Diagnostic Aid From Immunological Markers in Inflammasome Response

 

Last Updated: 27 Jun 2014

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Last Updated: 7 Aug 2007

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