Mutagen sensitivity

Common Name(s)

Mutagen sensitivity

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Mutagen sensitivity" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Mutagen sensitivity" returned 41 free, full-text research articles on human participants. First 3 results:

Gamma-ray-induced mutagen sensitivity and risk of sporadic breast cancer in young women: a case-control study.
 

Author(s): Li-E Wang, Chan H Han, Ping Xiong, Melissa L Bondy, Tse-Kuan Yu, Abenaa M Brewster, Sanjay Shete, Banu K Arun, Thomas A Buchholz, Qingyi Wei

Journal: Breast Cancer Res. Treat.. 2012 Apr;132(3):1147-55.

 

Hypersensitivity to radiation exposure has been suggested to be a risk factor for the development of breast cancer. In this case-control study of 515 young women (≤ 55 years) with newly diagnosed sporadic breast cancer and 402 cancer-free controls, we examined the radiosensitivity ...

Last Updated: 24 Apr 2012

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Mutagen sensitivity, tobacco smoking and breast cancer risk: a case-control study.
 

Author(s): Ourania Kosti, Celia Byrne, Katherine L Meeker, Kenshata M Watkins, Christopher A Loffredo, Peter G Shields, Marc D Schwartz, Shawna C Willey, Costanza Cocilovo, Yun-Ling Zheng

Journal: Carcinogenesis. 2010 Apr;31(4):654-9.

 

Given the high incidence of breast cancer and that more than half of cases remain unexplained, the need to identify risk factors for breast cancer remains. Deficiencies in DNA repair capacity have been associated with cancer risk. The mutagen sensitivity assay (MSA), a phenotypic ...

Last Updated: 31 Mar 2010

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Chromosomal alterations and mutagen sensitivity in human mucosal cells of the oropharynx and lymphocytes caused by BPDE.
 

Author(s): Maximilian Reiter, Philipp Baumeister, Sabina Zieger, Ulrich Harréus

Journal: Cancer Genomics Proteomics. ;6(5):247-54.

 

In addition to exogenous risk factors, the development of head and neck cancer is based on genetic alterations and individual mutagen sensitivity. DNA damage caused by xenobiotics is not uniformly distributed over the DNA, as certain chromosomes and genes are more likely to be damaged ...

Last Updated: 9 Dec 2009

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Mutagen sensitivity" returned 4 free, full-text review articles on human participants. First 3 results:

Evaluating the effects of genetic variants of DNA repair genes using cytogenetic mutagen sensitivity approaches.
 

Author(s): Sherif Z Abdel-Rahman, Randa A El-Zein

Journal: Biomarkers. 2011 Aug;16(5):393-404.

 

Mutagen sensitivity, measured in short-term cultures of peripheral blood lymphocytes by cytogenetic endpoints, is an indirect measure for DNA repair capacity and has been used for many years as a biomarker for intrinsic susceptibility for cancer. In this article, we briefly give an ...

Last Updated: 22 Jul 2011

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Automated scoring of lymphocyte micronuclei by the MetaSystems Metafer image cytometry system and its application in studies of human mutagen sensitivity and biodosimetry of genotoxin exposure.
 

Author(s): Andrea Rossnerova, Milada Spatova, Christian Schunck, Radim J Sram

Journal: Mutagenesis. 2011 Jan;26(1):169-75.

 

Automated image analysis scoring of micronuclei (MN) in cells can facilitate the objective and rapid measurement of genetic damage in mammalian and human cells. This approach was repeatedly developed and tested over the past two decades but none of the systems were sufficiently robust ...

Last Updated: 17 Dec 2010

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Mutagen sensitivity: a genetic predisposition factor for cancer.
 

Author(s): Xifeng Wu, Jian Gu, Margaret R Spitz

Journal: Cancer Res.. 2007 Apr;67(8):3493-5.

 

Mutagen sensitivity, measured by quantifying the chromatid breaks induced by mutagens in short-term cultures of peripheral blood lymphocytes, has been used as an indirect measure of DNA repair capacity. Numerous epidemiologic studies have suggested that mutagen sensitivity is a cancer ...

Last Updated: 18 Apr 2007

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.