MURCS association

Common Name(s)

MURCS association

MURCS association stands for (MU)llerian, (R)enal, (C)ervicothoracic (S)omite abnormalities and is a developmental disorder that primarily affects the reproductive and urinary systems.  Most individuals with MURCS association are female, although males can also have this condition.  Females with MURCS association can have an absent or abnormally shaped uterus. In rare cases, the vagina is also affected. Both males and females with MURCS association can have absent or abnormally formed reproductive tubes (usually the fallopian tubes in females and the vas deferens in males), kidney abnormalities, and short stature (adult height of less than 5 feet). Additional symptoms might include fused spinal bones in the neck and upper back and hearing loss. These symptoms may vary from person to person.  MURCS association is present at birth but may not be noticed until after puberty, especially when an affected female does not receive her first period.  This condition does not alter a personÕs life expectancy.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "MURCS association" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "MURCS association" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "MURCS association" returned 3 free, full-text research articles on human participants. First 3 results:

MURCS association: ultrasonographic findings and pathologic correlation.
 

Author(s): C O Fernandez, R D McFarland, C Timmons, R Ramus, D M Twickler

Journal: J Ultrasound Med. 1996 Dec;15(12):867-70.

 

MURCS association is a rare, lethal and unusual constellation of nonrandom findings that includes mullerian duct aplasia, renal aplasia, and cervicothoracic somite dysplasia.1-3 It has been described in 30 patients by Duncan and coworkers2 in 1979, in which report the authors proposed ...

Last Updated: 26 Feb 1997

Go To URL
MURCS association: case report and review.
 

Author(s): C Braun-Quentin, C Billes, B Böwing, D Kotzot

Journal: J. Med. Genet.. 1996 Jul;33(7):618-20.

 

We report on a 25 year old woman with aplasia of the Müllerian duct, unilateral renal agenesis, and anomalies of the cervicothoracic somites (MURCS association). Growth retardation and facial asymmetry were also present. A review of published reports allows MURCS association to be ...

Last Updated: 3 Dec 1996

Go To URL
Congenital corneal anaesthesia and the MURCS association: a case report.
 

Author(s): L Esakowitz, J R Yates

Journal: Br J Ophthalmol. 1988 Mar;72(3):236-8.

 

Bilateral corneal anaesthesia and reduced sensation in the distribution of the ophthalmic division of the fifth cranial nerve associated with neuroparalytic keratitis and reduced vision is described in a 26-year-old woman with absence of the fallopian tubes, uterus, and upper vagina, ...

Last Updated: 25 May 1988

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "MURCS association" returned 2 free, full-text review articles on human participants. First 3 results:

[Atipical form of Mayer-Rokitansky-Kuster-Hauser syndrome with renal malformation and skeletal abnormalities (MURCS association)].
 

Author(s): Mariana de Almeida Pinto Borges, Maria Lucia Elias Pires, Denise Leite Maia Monteiro, Suely Rodrigues Dos Santos

Journal: Rev Bras Ginecol Obstet. 2012 Mar;34(3):133-8.

 

The atypical and more severe form of Mayer-Rokitansky-Kuster-Hauser syndrome (MRKH) or MRKH type II is also known as MURCS association, an acronym meaning aplasia/hypoplasia of Müllerian ducts (MU), congenital renal dysplasia (R) and cervico-thoracic dysplasia (CS). It affects female ...

Last Updated: 10 Apr 2012

Go To URL
MURCS association--a review of 7 cases.
 

Author(s): P Mahajan, A Kher, A Khungar, M Bhat, M Sanklecha, B A Bharucha

Journal: J Postgrad Med. ;38(3):109-11.

 

MURCS association (Mullerian hypoplasia/aplasia, renal agenesis and cervicothoracic somite dysplasia) is emerging as the second most frequent cause of primary amenorrhoea after Turner syndrome. Seven cases have been described and analysed. All cases had absence of uterus and tubes ...

Last Updated: 24 Jun 1993

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.