Multicentric reticulohistiocytosis

Common Name(s)

Multicentric reticulohistiocytosis

Multicentric reticulohistiocytosis is a disease that is characterized by the presence of papules and nodules and associated with arthritis mutilans.  The disease can involve the skin, the bones, the tendons, the muscles, the joints, and nearly any other organ (e.g., eyes, larynx, thyroid, salivary glands, bone marrow, heart, lung, kidney, liver, gastrointestinal tract). In the majority of cases, the cause of multicentric reticulohistiocytosis is unknown; however, it has been associated with an underlying cancer in about one fourth of cases, suggesting that it may be a paraneoplastic syndrome.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Multicentric reticulohistiocytosis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Multicentric reticulohistiocytosis" returned 26 free, full-text research articles on human participants. First 3 results:

Bilateral Total Hip Arthroplasty in a Rare Case of Multicentric Reticulohistiocytosis.
 

Author(s): Balaji Saibaba, Ramesh Kumar Sen, Ashim Das, Aman Sharma

Journal: Clin Orthop Surg. 2015 Dec;7(4):509-14.

 

Multicentric reticulohistiocytosis (MRH) is a rare systemic disease, which commonly manifests as muco-cutaneous papulonodules and inflammatory erosive polyarthropathy. In this research, we report the clinical manifestations and management of a rare case of MRH with destructive arthropathy ...

Last Updated: 7 Dec 2015

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Successful Treatment of Multicentric Reticulohistiocytosis with Adalimumab, Prednisolone and Methotrexate.
 

Author(s): Sei-Ichiro Motegi, Yukio Yonemoto, Shinya Yanagisawa, Sayaka Toki, Akihiko Uchiyama, Kazuya Yamada, Osamu Ishikawa

Journal: Acta Derm. Venereol.. 2016 Jan;96(1):124-5.

 

Last Updated: 20 Jan 2016

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Erythema, papules, and arthralgia associated with liver cancer: report of a rare case of multicentric reticulohistiocytosis.
 

Author(s): Liang Hu, Jun-Hua Mei, Jin Xia, Quan-Shui Hao, Li-Ping Cheng, Yao-Hua Wu

Journal:

 

We report a rare case of multicentric reticulohistiocytosis (MRH) associated with liver carcinoma. A 36-year-old man who had been diagnosed as having liver carcinoma for 2 years presented with a 2-month history of multiple papulonodules on the face, ears, neck, and upper chest, accompanied ...

Last Updated: 5 Jun 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Multicentric reticulohistiocytosis" returned 3 free, full-text review articles on human participants. First 3 results:

Multicentric reticulohistiocytosis in a Malaysian Chinese lady: a case report and review of literature .
 

Author(s): Felix Boon Bin Yap

Journal:

 

A 36-year-old Malaysian woman with erosive arthritis presented with multiple asymptomatic skin colored papulonodules on the hands, elbows, knees, ears, and feet; many macules, papules, and plaques were photodistributed. Progressive, erosive arthritis began about 18 months after the ...

Last Updated: 13 Mar 2009

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Multicentric reticulohistiocytosis presenting with papulonodular skin eruption and polyarthritis.
 

Author(s): Shahram Baghestani, Farrokh Khosravi, Mohsen Dehghani Zahedani, Abdol-Ali Mahboobi

Journal: Eur J Dermatol. ;15(3):196-200.

 

Multicentric reticulohistiocytosis is a rare multisystem disease, presenting with skin lesions and erosive polyarthritis, which is often associated with malignancy. A 2 year untreated natural course of multicentric reticulohistiocytosis, in which the typical nodular skin manifestation ...

Last Updated: 23 May 2005

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Multicentric reticulohistiocytosis and pregnancy.
 

Author(s): Anna Brackenridge, Thikra Bashir, Trevor Wheatley

Journal: BJOG. 2005 May;112(5):672-3.

 

Last Updated: 21 Apr 2005

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

International Rare Histiocytic Disorders Registry (IRHDR)
 

Status: Recruiting

Condition Summary: Rare Histiocytic Disorders (RHDs); Juvenile Xanthogranuloma (JXG); Reticulohistiocytoma (Epithelioid Histiocytoma); Xanthoma Disseminatum (XD); Multicentric Reticulohistiocytosis (MRH); Systemic Juvenile Xanthogranuloma; Erdheim-Chester Disease (ECD); Multi-system Rosai-Dorfman Disease (RDD)

 

Last Updated: 25 Apr 2016

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