Multicentric reticulohistiocytosis

Common Name(s)

Multicentric reticulohistiocytosis

Multicentric reticulohistiocytosis is a disease that is characterized by the presence of papules and nodules and associated with arthritis mutilans.  The disease can involve the skin, the bones, the tendons, the muscles, the joints, and nearly any other organ (e.g., eyes, larynx, thyroid, salivary glands, bone marrow, heart, lung, kidney, liver, gastrointestinal tract). In the majority of cases, the cause of multicentric reticulohistiocytosis is unknown; however, it has been associated with an underlying cancer in about one fourth of cases, suggesting that it may be a paraneoplastic syndrome.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Multicentric reticulohistiocytosis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Multicentric reticulohistiocytosis" returned 26 free, full-text research articles on human participants. First 3 results:

Multicentric Reticulohistiocytosis with Dermatomyositis-like Eruptions.
 

Author(s): Natsuki Shima, Takamasa Murosaki, Takao Nagashima, Masahiro Iwamoto, Yusuke Amano, Naomi Nakano, Mamitaro Ohtsuki, Seiji Minota

Journal: Intern. Med.. 2017 ;56(15):2063-2066.

 

A 68-year-old man presented with polyarthritis, proximal muscle weakness, and erythema of the face, arms, neck, and anterior chest that resembled the V-neck sign. Initially, dermatomyositis (DM) was considered because of the erythema, polyarthritis, and muscle weakness. He also had ...

Last Updated: 31 Dec 1969

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Efficacy of Vinblastine and Prednisone in Multicentric Reticulohistiocytosis With Onset in Infancy.
 

Author(s): Vijay Kumar Jha, Ravindra Kumar, Abhijeet Kunwar, Ankur Singh, Mahendra Kumar, Mohan Kumar, Rajniti Prasad

Journal: Pediatrics. 2016 Jun;137(6):.

 

Multicentric reticulohistiocytosis (MRH) is a rare histiocytic proliferative disorder of uncertain etiology, characterized by mucocutaneous papulonodular lesions and progressive, symmetric erosive arthritis. MRH can coexist with various autoimmune disorders, tuberculosis, and malignancy. ...

Last Updated: 31 Dec 1969

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Bilateral Total Hip Arthroplasty in a Rare Case of Multicentric Reticulohistiocytosis.
 

Author(s): Balaji Saibaba, Ramesh Kumar Sen, Ashim Das, Aman Sharma

Journal: Clin Orthop Surg. 2015 Dec;7(4):509-14.

 

Multicentric reticulohistiocytosis (MRH) is a rare systemic disease, which commonly manifests as muco-cutaneous papulonodules and inflammatory erosive polyarthropathy. In this research, we report the clinical manifestations and management of a rare case of MRH with destructive arthropathy ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Multicentric reticulohistiocytosis" returned 3 free, full-text review articles on human participants. First 3 results:

Tumor necrosis factor antagonists in the treatment of multicentric reticulohistiocytosis: Current clinical evidence.
 

Author(s): Hongjun Zhao, Chunmei Wu, Mengyun Wu, Yaou Zhou, Honglin Zhu, Yisha Li, Yunhui You, Hui Luo, Lijing Wang, Xiaoxia Zuo

Journal: Mol Med Rep. 2016 Jul;14(1):209-17.

 

Multicentric reticulohistiocytosis (MRH) is a rare and debilitating systemic disorder characterized by cutaneous nodules and destructive polyarthritis. Due to its unknown etiology, the treatment of MRH varies with different rates of success, which causes treatment options to be rather ...

Last Updated: 31 Dec 1969

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Multicentric reticulohistiocytosis in a Malaysian Chinese lady: a case report and review of literature .
 

Author(s): Felix Boon Bin Yap

Journal:

 

A 36-year-old Malaysian woman with erosive arthritis presented with multiple asymptomatic skin colored papulonodules on the hands, elbows, knees, ears, and feet; many macules, papules, and plaques were photodistributed. Progressive, erosive arthritis began about 18 months after the ...

Last Updated: 31 Dec 1969

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Multicentric reticulohistiocytosis and pregnancy.
 

Author(s): Anna Brackenridge, Thikra Bashir, Trevor Wheatley

Journal: BJOG. 2005 May;112(5):672-3.

 

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

International Rare Histiocytic Disorders Registry (IRHDR)
 

Status: Recruiting

Condition Summary: Rare Histiocytic Disorders (RHDs); Juvenile Xanthogranuloma (JXG); Reticulohistiocytoma (Epithelioid Histiocytoma); Xanthoma Disseminatum (XD); Multicentric Reticulohistiocytosis (MRH); Systemic Juvenile Xanthogranuloma; Erdheim-Chester Disease (ECD); Multi-system Rosai-Dorfman Disease (RDD)

 

Last Updated: 18 Apr 2018

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