Mucoepidermoid carcinoma

Common Name(s)

Mucoepidermoid carcinoma

Mucoepidermoid carcinoma is a type of cancer that usually develops in areas of the body where saliva is produced. Mucoepidermoid carcinoma is the most common cancer of the salivary glands. The largest saliva-producing gland and the most common location where this cancer develops is called the parotid gland. The parotid gland is found on either side of the face, just in front of the ears. Mucoepidermoid carcinoma can also develop in the submandibular glands, which are located under the jawbone, the sublingual glands, which are located under the tongue, or in the lungs. Cancers form when a mutation in DNA causes certain cells to grow out of control, sometimes forming a lump or a tumor. Some of these cancerous cells can break off and spread to other parts of the body where they will continue to grow. This process is known as metastasis.

Mucoepidermoid carcinoma is most commonly found in adults between the ages of 40 and 60, although it can appear in all age groups. The most common symptoms of mucoepidermoid carcinoma include weakness of the muscles of the face, facial numbness, and the presence of a swelling or lump near the neck, mouth, or cheeks. Depending on the size of the tumor, individuals may experience difficulty swallowing and opening the mouth. Diagnosis may involve a physical exam, imaging studies, and other laboratory studies.

Treatment for mucoepidermoid carcinoma depends on many factors such as how large the cancer is and if it has spread to other areas of the body. If you or a family member has been diagnosed with mucoepidermoid carcinoma, talk to your doctor about the most current treatment options. Support groups are also available for more resources and information.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Mucoepidermoid carcinoma" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Mucoepidermoid carcinoma" returned 164 free, full-text research articles on human participants. First 3 results:

Nuclear Multidrug Resistance-Related Protein 1 Is Highly Associated with Better Prognosis of Human Mucoepidermoid Carcinoma through the Suppression of Cell Proliferation, Migration and Invasion.
 

Author(s): Bo-Lei Cai, Yan Li, Liang-Liang Shen, Jin-Long Zhao, Yuan Liu, Jun-Zheng Wu, Yan-Pu Liu, Bo Yu

Journal:

 

Multidrug resistance-related protein 1 (MRP1) overexpression is a well acknowledged predictor of poor response to chemotherapy, but MRP1 also correlated to better prognosis in some reports, especially for patients not pretreated with chemotherapy. In our previous study, we found nuclear ...

Last Updated: 2 Feb 2016

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About a rare tumor of the upper lip: the mucoepidermoid carcinoma.
 

Author(s): Mohamed Mliha Touati, Mohammed Lakouichmi

Journal:

 

Last Updated: 15 Dec 2015

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Mucoepidermoid Carcinoma of the Tracheobronchial Tree.
 

Author(s): Walid K Abu Saleh, Odeaa Aljabbari, Mahesh Ramchandani

Journal: Methodist Debakey Cardiovasc J. ;11(3):192-4.

 

Primary salivary type lung cancers are extremely rare intrathoracic malignancies. Mucoepidermoid tumor is one of the salivary gland tumors that originates from submucosal glands of the tracheobronchial tree. These are very slow-growing low-grade malignant tumors. Surgery is the mainstay ...

Last Updated: 4 Dec 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Mucoepidermoid carcinoma" returned 13 free, full-text review articles on human participants. First 3 results:

Mucoepidermoid carcinoma of esophagus combined with squamous carcinoma of lung: A case report and literature review.
 

Author(s): Chaoxing Liu, Yahong Zhao, Weiwei Chu, Futong Zhang, Zhenping Zhang

Journal: J Cancer Res Ther. ;11(3):658.

 

Mucoepidermoid carcinoma (MEC) is typically located in the salivary, lacrimal, and tracheobronchial glands and rarely presents in the esophagus. MEC is commonly characterized by squamous cells, mucus-secreting cells, and intermediate cells. This report presents the case of a 57-years-old ...

Last Updated: 13 Oct 2015

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Primary Intraosseous Mucoepidermoid Carcinoma of the Maxilla.
 

Author(s): S M Nallamilli, R Tatapudi, R S Reddy, M Ravikanth, N Rajesh

Journal: Ghana Med J. 2015 Jun;49(2):120-3.

 

Primary intraosseous mucoepidermoid carcinoma (PIOC) is an infrequent malignancy of the head and neck that exhibits diverse biological behavior. The rareness of the location for a salivary gland tumor and the clinical and radiographic manifestations, suggestive of an odontogenic lesion ...

Last Updated: 4 Sep 2015

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Sclerosing mucoepidermoid carcinoma with eosinophilia of thyroid gland in a male patient: a case report and literature review.
 

Author(s): Chi-Yun Lai, Tzu-Chieh Chao, Jen-Der Lin, Chuen Hsueh

Journal:

 

Sclerosing mucoepidermoid carcinoma with eosinophilia (SMECE) was first described by Chan et al in 1991. It is characterized by nest or strands of epidermoid tumor cells with squamous differentiation, rare mucous cells, prominent sclerotic stroma, eosinophilic and lymphoplasmacytic ...

Last Updated: 20 Jul 2015

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Transoral Robotic Surgery in Treating Patients With Benign or Malignant Tumors of the Head and Neck
 

Status: Recruiting

Condition Summary: Recurrent Adenoid Cystic Carcinoma of the Oral Cavity; Recurrent Mucoepidermoid Carcinoma of the Oral Cavity; Recurrent Squamous Cell Carcinoma of the Hypopharynx; Recurrent Squamous Cell Carcinoma of the Larynx; Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity; Recurrent Verrucous Carcinoma of the Larynx; Recurrent Verrucous Carcinoma of the Oral Cavity; Stage 0 Hypopharyngeal Cancer; Stage 0 Laryngeal Cancer; Stage 0 Lip and Oral Cavity Cancer; Stage I Adenoid Cystic Carcinoma of the Oral Cavity; Stage I Mucoepidermoid Carcinoma of the Oral Cavity; Stage I Squamous Cell Carcinoma of the Hypopharynx; Stage I Squamous Cell Carcinoma of the Larynx; Stage I Squamous Cell Carcinoma of the Lip and Oral Cavity; Stage I Verrucous Carcinoma of the Larynx; Stage I Verrucous Carcinoma of the Oral Cavity; Stage II Adenoid Cystic Carcinoma of the Oral Cavity; Stage II Mucoepidermoid Carcinoma of the Oral Cavity; Stage II Squamous Cell Carcinoma of the Hypopharynx; Stage II Squamous Cell Carcinoma of the Larynx; Stage II Squamous Cell Carcinoma of the Lip and Oral Cavity; Stage II Verrucous Carcinoma of the Larynx; Stage II Verrucous Carcinoma of the Oral Cavity; Stage III Adenoid Cystic Carcinoma of the Oral Cavity; Stage III Mucoepidermoid Carcinoma of the Oral Cavity; Stage III Squamous Cell Carcinoma of the Hypopharynx; Stage III Squamous Cell Carcinoma of the Larynx; Stage III Squamous Cell Carcinoma of the Lip and Oral Cavity; Stage III Verrucous Carcinoma of the Larynx; Stage III Verrucous Carcinoma of the Oral Cavity; Stage IV Squamous Cell Carcinoma of the Hypopharynx; Stage IVA Adenoid Cystic Carcinoma of the Oral Cavity; Stage IVA Mucoepidermoid Carcinoma of the Oral Cavity; Stage IVA Squamous Cell Carcinoma of the Larynx; Stage IVA Squamous Cell Carcinoma of the Lip and Oral Cavity; Stage IVA Verrucous Carcinoma of the Larynx; Stage IVA Verrucous Carcinoma of the Oral Cavity; Stage IVB Adenoid Cystic Carcinoma of the Oral Cavity; Stage IVB Mucoepidermoid Carcinoma of the Oral Cavity; Stage IVB Squamous Cell Carcinoma of the Larynx; Stage IVB Squamous Cell Carcinoma of the Lip and Oral Cavity; Stage IVB Verrucous Carcinoma of the Larynx; Stage IVB Verrucous Carcinoma of the Oral Cavity; Stage IVC Adenoid Cystic Carcinoma of the Oral Cavity; Stage IVC Mucoepidermoid Carcinoma of the Oral Cavity; Stage IVC Squamous Cell Carcinoma of the Larynx; Stage IVC Squamous Cell Carcinoma of the Lip and Oral Cavity; Stage IVC Verrucous Carcinoma of the Larynx; Stage IVC Verrucous Carcinoma of the Oral Cavity; Tongue Cancer

 

Last Updated: 26 Mar 2015

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Intensity-Modulated or Proton Radiation Therapy for Sinonasal Malignancy
 

Status: Recruiting

Condition Summary: Adenoid Cystic Carcinoma; Squamous Cell Carcinoma; Sinonasal Carcinoma; Sinonasal Undifferentiated Carcinoma; Mucoepidermoid Carcinoma; Schneiderian Carcinoma; Myoepithelial Carcinoma; Esthesioneuroblastoma; Melanoma

 

Last Updated: 10 Feb 2016

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18F FPPRGD2 PET/CT or PET/MRI in Predicting Early Response in Patients With Cancer Receiving Anti-Angiogenesis Therapy
 

Status: Recruiting

Condition Summary: Adult Giant Cell Glioblastoma; Adult Glioblastoma; Adult Gliosarcoma; Male Breast Cancer; Metastatic Squamous Neck Cancer With Occult Primary Squamous Cell Carcinoma; Recurrent Adenoid Cystic Carcinoma of the Oral Cavity; Recurrent Adult Brain Tumor; Recurrent Basal Cell Carcinoma of the Lip; Recurrent Breast Cancer; Recurrent Colon Cancer; Recurrent Esthesioneuroblastoma of the Paranasal Sinus and Nasal Cavity; Recurrent Hypopharyngeal Cancer; Recurrent Inverted Papilloma of the Paranasal Sinus and Nasal Cavity; Recurrent Laryngeal Cancer; Recurrent Lip and Oral Cavity Cancer; Recurrent Lymphoepithelioma of the Nasopharynx; Recurrent Lymphoepithelioma of the Oropharynx; Recurrent Metastatic Squamous Neck Cancer With Occult Primary; Recurrent Midline Lethal Granuloma of the Paranasal Sinus and Nasal Cavity; Recurrent Mucoepidermoid Carcinoma of the Oral Cavity; Recurrent Nasopharyngeal Cancer; Recurrent Non-small Cell Lung Cancer; Recurrent Oropharyngeal Cancer; Recurrent Pancreatic Cancer; Recurrent Paranasal Sinus and Nasal Cavity Cancer; Recurrent Rectal Cancer; Recurrent Renal Cell Cancer; Recurrent Salivary Gland Cancer; Stage IIIA Breast Cancer; Stage IIIA Non-small Cell Lung Cancer; Stage IIIB Breast Cancer; Stage IIIB Non-small Cell Lung Cancer; Stage IIIC Breast Cancer; Stage IV Breast Cancer; Stage IV Non-small Cell Lung Cancer; Stage IV Pancreatic Cancer; Stage IV Renal Cell Cancer; Stage IVA Colon Cancer; Stage IVA Rectal Cancer; Stage IVA Salivary Gland Cancer; Stage IVB Colon Cancer; Stage IVB Salivary Gland Cancer; Stage IVC Salivary Gland Cancer; Tongue Cancer; Unspecified Adult Solid Tumor, Protocol Specific

 

Last Updated: 16 Nov 2015

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