Motor neuropathy

Common Name(s)

Motor neuropathy

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Motor neuropathy" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Motor neuropathy" returned 143 free, full-text research articles on human participants. First 3 results:

Synaptotagmin 2 mutations cause an autosomal-dominant form of lambert-eaton myasthenic syndrome and nonprogressive motor neuropathy.
 

Author(s): David N Herrmann, Rita Horvath, Janet E Sowden, Michael Gonzalez, Michael Gonzales, Avencia Sanchez-Mejias, Zhuo Guan, Roger G Whittaker, Jorge L Almodovar, Maria Lane, Boglarka Bansagi, Angela Pyle, Veronika Boczonadi, Hanns Lochm├╝ller, Helen Griffin, Patrick F Chinnery, Thomas E Lloyd, J Troy Littleton, Stephan Zuchner

Journal: Am. J. Hum. Genet.. 2014 Sep;95(3):332-9.

 

Synaptotagmin 2 is a synaptic vesicle protein that functions as a calcium sensor for neurotransmission but has not been previously associated with human disease. Via whole-exome sequencing, we identified heterozygous missense mutations in the C2B calcium-binding domain of the gene ...

Last Updated: 6 Sep 2014

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A family with distal hereditary motor neuropathy and a K141Q mutation of small heat shock protein HSPB1.
 

Author(s): Kengo Maeda, Ryo Idehara, Akihiro Hashiguchi, Hiroshi Takashima

Journal: Intern. Med.. 2014 ;53(15):1655-8.

 

We herein describe a Japanese family with distal hereditary motor neuropathy carrying a K141Q mutation of small heat shock protein HSPB1. Two patients among them had late onset disease (older than 50 years). The muscles of the distal legs were weak and atrophic. Sensory and autonomic ...

Last Updated: 4 Aug 2014

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ATP7A trafficking and mechanisms underlying the distal motor neuropathy induced by mutations in ATP7A.
 

Author(s): Ling Yi, Stephen Kaler

Journal: Ann. N. Y. Acad. Sci.. 2014 May;1314():49-54.

 

Diverse mutations in the gene encoding the copper transporter ATP7A lead to X-linked recessive Menkes disease or occipital horn syndrome. Recently, two unique ATP7A missense mutations, T994I and P1386S, were shown to cause isolated adult-onset distal motor neuropathy. These mutations ...

Last Updated: 13 May 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Motor neuropathy" returned 6 free, full-text review articles on human participants. First 3 results:

Multifocal motor neuropathy, multifocal acquired demyelinating sensory and motor neuropathy, and other chronic acquired demyelinating polyneuropathy variants.
 

Author(s): Mazen M Dimachkie, Richard J Barohn, Jonathan Katz

Journal: Neurol Clin. 2013 May;31(2):533-55.

 

Chronic acquired demyelinating neuropathies (CADP) constitute an important group of immune neuromuscular disorders affecting myelin. This article discusses CADP with emphasis on multifocal motor neuropathy, multifocal acquired demyelinating sensory and motor neuropathy, distal acquired ...

Last Updated: 6 May 2013

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Multifocal motor neuropathy.
 

Author(s): Thy P Nguyen, Vinay Chaudhry

Journal: Neurol India. ;59(5):700-6.

 

Multifocal motor neuropathy (MMN) is a unique disorder characterized by slowly progressive, asymmetric, distal and upper limb predominant weakness without significant sensory abnormalities. Electrophysiology is crucial to the diagnosis, revealing the hallmark partial conduction block. ...

Last Updated: 24 Oct 2011

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Intravenous immunoglobulin treatment in multifocal motor neuropathy.
 

Author(s): W-Ludo van der Pol, Elisabeth A Cats, Leonard H van den Berg

Journal: J. Clin. Immunol.. 2010 May;30 Suppl 1():S79-83.

 

Multifocal motor neuropathy (MMN) is characterized by asymmetric weakness of limbs and the electrophysiological finding of conduction block in motor nerves. Conduction block is the inability of nerves to propagate action potentials and is probably caused by immune-mediated dysfunction ...

Last Updated: 10 Jun 2010

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

LIME Study (LFB IVIg MMN Efficacy Study)
 

Status: Recruiting

Condition Summary: Motor Neuron Disease

 

Last Updated: 6 Jul 2015

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Disability Severity Scale (DSI) and Hereditary Motor and Sensory Neuropathy Overall Disability Scale (HMSN-R-ODS)
 

Status: Recruiting

Condition Summary: Charcot Marie Tooth Disease; Inherited Peripheral Neuropathy

 

Last Updated: 15 May 2015

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Acetyl-l-carnitine to Enhance Nerve Regeneration in Carpal Tunnel Syndrome
 

Status: Not yet recruiting

Condition Summary: Carpal Tunnel Syndrome; Compression Neuropathy

 

Last Updated: 20 Apr 2015

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