Motor neuron disease

Common Name(s)

Motor neuron disease

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Motor neuron disease" for support, advocacy or research.

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The ALS Association - Evergreen Chapter

Leading the fight to treat and cure ALS through global research and nationwide advocacy while also empowering people with Lou Gehrig's Disease and their families to live fuller lives by providing them with compassionate care and support.

Last Updated: 12 Jun 2013

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Motor neuron disease" for support, advocacy or research.

Logo
The ALS Association - Evergreen Chapter

Leading the fight to treat and cure ALS through global research and nationwide advocacy while also empowering people with Lou Gehrig's Disease and their families to live fuller lives by providing them with compassionate care and support.

http://www.alsa-ec.org

Last Updated: 12 Jun 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Motor neuron disease" returned 224 free, full-text research articles on human participants. First 3 results:

Development of patient decision support tools for motor neuron disease using stakeholder consultation: a study protocol.
 

Author(s): Anne Hogden, David Greenfield, Jashelle Caga, Xiongcai Cai

Journal:

 

Motor neuron disease (MND) is a terminal, progressive, multisystem disorder. Well-timed decisions are key to effective symptom management. To date, there are few published decision support tools, also known as decision aids, to guide patients in making ongoing choices for symptom ...

Last Updated: 7 Apr 2016

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Neuromuscular Ultrasound in the Assessment of Polyneuropathies and Motor Neuron Disease.
 

Author(s): Jack Shen, Michael S Cartwright

Journal: J Clin Neurophysiol. 2016 Apr;33(2):86-93.

 

Neuromuscular ultrasound is an emerging technology for the evaluation of conditions affecting nerve and muscle, with most of the research focusing on focal neuropathies. Despite this focus, researchers have also investigated the ultrasonographic changes that occur in the nerves and ...

Last Updated: 2 Apr 2016

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Primary Lateral Sclerosis and Early Upper Motor Neuron Disease: Characteristics of a Cross-Sectional Population.
 

Author(s): Christina N Fournier, Alyssa Murphy, Lorena Loci, Hiroshi Mitsumoto, Catherine Lomen-Hoerth, Yasushi Kisanuki, Zachary Simmons, Nicholas J Maragakis, April L McVey, Tawfiq Al-Lahham, Terry D Heiman-Patterson, Jinsy Andrews, Erin McDonnell, Merit Cudkowicz, Nazem Atassi

Journal: J Clin Neuromuscul Dis. 2016 Mar;17(3):99-105.

 

The goals of this study were to characterize clinical and electrophysiologic findings of subjects with upper motor neuron disease and to explore feasibility of clinical trials in this population.

Last Updated: 24 Feb 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Motor neuron disease" returned 22 free, full-text review articles on human participants. First 3 results:

Patterns of Weakness, Classification of Motor Neuron Disease, and Clinical Diagnosis of Sporadic Amyotrophic Lateral Sclerosis.
 

Author(s): Jeffrey M Statland, Richard J Barohn, April L McVey, Jonathan S Katz, Mazen M Dimachkie

Journal: Neurol Clin. 2015 Nov;33(4):735-48.

 

When approaching a patient with suspected motor neuron disease (MND), the pattern of weakness on examination helps distinguish MND from other diseases of peripheral nerves, the neuromuscular junction, or muscle. MND is a clinical diagnosis supported by findings on electrodiagnostic ...

Last Updated: 30 Oct 2015

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Challenges in the Understanding and Treatment of Amyotrophic Lateral Sclerosis/Motor Neuron Disease.
 

Author(s): Jeffrey Rosenfeld, Michael J Strong

Journal: Neurotherapeutics. 2015 Apr;12(2):317-25.

 

With the acceleration in our understanding of ALS and the related motor neuron disease has come even greater challenges in reconciling all of the proposed pathogenic mechanisms and how this will translate into impactful treatments. Fundamental issues such as diagnostic definition(s) ...

Last Updated: 21 Apr 2015

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Motor neuron disease in 2014. Biomarkers for ALS--in search of the Promised Land.
 

Author(s): Adriano ChiĆ², Bryan J Traynor

Journal: Nat Rev Neurol. 2015 Feb;11(2):72-4.

 

The past year has seen some extraordinary activity in clinical amyotrophic lateral sclerosis (ALS) research. Two trials were completed, with negative results, but the discovery of novel ALS-associated genes, and body fluid and imaging biomarkers warrants cautious optimism. Here, we ...

Last Updated: 6 Feb 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Phase 1 Dose Escalation and PK Study of Cu(II)ATSM in ALS/MND
 

Status: Recruiting

Condition Summary: Amyotrophic Lateral Sclerosis; Motor Neuron Disease

 

Last Updated: 6 Mar 2017

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Use of Dalfampridin in Primary Lateral Sclerosis
 

Status: Recruiting

Condition Summary: Motor Neuron Disease, Upper

 

Last Updated: 4 Nov 2016

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Deep Phenotyping in Patients With ALS
 

Status: Recruiting

Condition Summary: ALS; Motor Neuron Disease

 

Last Updated: 9 Feb 2017

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