Motor neuron disease

Common Name(s)

Motor neuron disease

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Motor neuron disease" for support, advocacy or research.

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The ALS Association - Evergreen Chapter

Leading the fight to treat and cure ALS through global research and nationwide advocacy while also empowering people with Lou Gehrig's Disease and their families to live fuller lives by providing them with compassionate care and support.

Last Updated: 12 Jun 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Motor neuron disease" for support, advocacy or research.

Logo
The ALS Association - Evergreen Chapter

Leading the fight to treat and cure ALS through global research and nationwide advocacy while also empowering people with Lou Gehrig's Disease and their families to live fuller lives by providing them with compassionate care and support.

http://www.alsa-ec.org

Last Updated: 12 Jun 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Motor neuron disease" returned 197 free, full-text research articles on human participants. First 3 results:

A zebrafish model exemplifies the long preclinical period of motor neuron disease.
 

Author(s): Tennore M Ramesh, Pamela J Shaw, Jonathan McDearmid

Journal: J. Neurol. Neurosurg. Psychiatr.. 2014 Nov;85(11):1288-9.

 

Last Updated: 18 Oct 2014

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Plastic changes in the spinal cord in motor neuron disease.
 

Author(s): Francesco Fornai, Michela Ferrucci, Paola Lenzi, Alessandra Falleni, Francesca Biagioni, Marina Flaibani, Gabriele Siciliano, Francesco Giannessi, Antonio Paparelli

Journal: Biomed Res Int. 2014 ;2014():670756.

 

In the present paper, we analyze the cell number within lamina X at the end stage of disease in a G93A mouse model of ALS; the effects induced by lithium; the stem-cell like phenotype of lamina X cells during ALS; the differentiation of these cells towards either a glial or neuronal ...

Last Updated: 15 May 2014

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Muscle expression of mutant androgen receptor accounts for systemic and motor neuron disease phenotypes in spinal and bulbar muscular atrophy.
 

Author(s): Constanza J Cortes, Shuo-Chien Ling, Ling T Guo, Gene Hung, Taiji Tsunemi, Linda Ly, Seiya Tokunaga, Edith Lopez, Bryce L Sopher, C Frank Bennett, G Diane Shelton, Don W Cleveland, Albert R La Spada

Journal: Neuron. 2014 Apr;82(2):295-307.

 

X-linked spinal and bulbar muscular atrophy (SBMA) is characterized by adult-onset muscle weakness and lower motor neuron degeneration. SBMA is caused by CAG-polyglutamine (polyQ) repeat expansions in the androgen receptor (AR) gene. Pathological findings include motor neuron loss, ...

Last Updated: 18 Apr 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Motor neuron disease" returned 18 free, full-text review articles on human participants. First 3 results:

Neurogenic and myogenic contributions to hereditary motor neuron disease.
 

Author(s): Katherine V Bricceno, Kenneth H Fischbeck, Barrington G Burnett

Journal: Neurodegener Dis. 2012 ;9(4):199-209.

 

Spinal muscular atrophy and spinal and bulbar muscular atrophy are characterized by lower motor neuron loss and muscle atrophy. Although it is accepted that motor neuron loss is a primary event in disease pathogenesis, inherent defects in muscle may also contribute to the disease ...

Last Updated: 15 May 2012

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Reviewing evidences on the management of patients with motor neuron disease.
 

Author(s): C N Lee

Journal: Hong Kong Med J. 2012 Feb;18(1):48-55.

 

To review evidences on the management of patients with motor neuron disease.

Last Updated: 3 Feb 2012

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Frontotemporal dementia and motor neuron disease: report of 3 cases in Taiwan and literature review.
 

Author(s): Kai-Hsiang Chen, Ming-Jang Chiu, Ting-Wen Cheng, Jen-Jen Su

Journal: Acta Neurol Taiwan. 2011 Sep;20(3):202-8.

 

Case reports and a review of literature of the coexistence of motor neuron disease (MND) and frontotemporal dementia (FTD).

Last Updated: 19 Oct 2011

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Safety and Efficacy on Spasticity Symptoms of a Cannabis Sativa Extract in Motor Neuron Disease
 

Status: Recruiting

Condition Summary: Motor Neuron Disease; Amyotrophic Lateral Sclerosis (ALS)

 

Last Updated: 24 Jan 2013

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Cell Therapy for Motor Neuron Disease/Amyotrophic Lateral Sclerosis
 

Status: Recruiting

Condition Summary: Motor Neuron Disease/Amyotrophic Lateral Sclerosis

 

Last Updated: 13 Sep 2014

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Genetic Study of Familial and Sporadic ALS/Motor Neuron Disease, Miyoshi Myopathy and Other Neuromuscular Disorders
 

Status: Recruiting

Condition Summary: Amyotrophic Lateral Sclerosis; Frontotemporal Dementia; PLS; Motor Neuron Disease; Lou Gehrigs Disease; Familial Disease; Amyotrophic Lateral Sclerosis, Sporadic; Muscular Dystrophy; Miyoshi Myopathy

 

Last Updated: 27 Jan 2015

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