Monkeypox

Common Name(s)

Monkeypox

Monkeypox is a virus that is very dangerous to humans. It is similar in symptoms to smallpox, and occurs sporadically in parts of Africa. Human monkepox first appeared in 1970 in the Democratic Republic of Congo, and since then has been reported in rural areas of the Congo Basin and western African. The disease can be spread through direct contact with the blood, bodily fluids, or rashes of infected animals, and also through transmission from human-to-human, through close contact. Signs and symptoms of monkeypox include fever, intense headache, swelling of the lymph node, muscle ache, and an intense lack of energy. Symptoms can then progress to skin eruptions on the palms of the hands and soles of the feet. Symptoms of monkeypox typically last 14 to 21 days, and the disease can be fatal.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Monkeypox" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Monkeypox" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Monkeypox" returned 96 free, full-text research articles on human participants. First 3 results:

A highly specific monoclonal antibody against monkeypox virus detects the heparin binding domain of A27.
 

Author(s): Laura J Hughes, Jason Goldstein, Jan Pohl, Jay W Hooper, R Lee Pitts, Michael B Townsend, Dennis Bagarozzi, Inger K Damon, Kevin L Karem

Journal: Virology. 2014 Sep;464-465():264-73.

 

The eradication of smallpox and the cessation of global vaccination led to the increased prevalence of human infections in Central Africa. Serologic and protein-based diagnostic assay for MPXV detection is difficult due to cross-reactive antibodies that do not differentiate between ...

Last Updated: 6 Sep 2014

Go To URL
Genomic variability of monkeypox virus among humans, Democratic Republic of the Congo.
 

Author(s): Jeffrey R Kugelman, Sara C Johnston, Prime M Mulembakani, Neville Kisalu, Michael S Lee, Galina Koroleva, Sarah E McCarthy, Marie C Gestole, Nathan D Wolfe, Joseph N Fair, Bradley S Schneider, Linda L Wright, John Huggins, Chris A Whitehouse, Emile Okitolonda Wemakoy, Jean Jacques Muyembe-Tamfum, Lisa E Hensley, Gustavo F Palacios, Anne W Rimoin

Journal: Emerging Infect. Dis.. 2014 Feb;20(2):232-9.

 

Monkeypox virus is a zoonotic virus endemic to Central Africa. Although active disease surveillance has assessed monkeypox disease prevalence and geographic range, information about virus diversity is lacking. We therefore assessed genome diversity of viruses in 60 samples obtained ...

Last Updated: 24 Jan 2014

Go To URL
Mapping monkeypox transmission risk through time and space in the Congo Basin.
 

Author(s): Yoshinori Nakazawa, R Ryan Lash, Darin S Carroll, Inger K Damon, Kevin L Karem, Mary G Reynolds, Jorge E Osorio, Tonie E Rocke, Jean M Malekani, Jean-Jacques Muyembe, Pierre Formenty, A Townsend Peterson

Journal:

 

Monkeypox is a major public health concern in the Congo Basin area, with changing patterns of human case occurrences reported in recent years. Whether this trend results from better surveillance and detection methods, reduced proportions of vaccinated vs. non-vaccinated human populations, ...

Last Updated: 16 Sep 2013

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Monkeypox" returned 9 free, full-text review articles on human participants. First 3 results:

Human monkeypox.
 

Author(s): Andrea M McCollum, Inger K Damon

Journal: Clin. Infect. Dis.. 2014 Jan;58(2):260-7.

 

Human monkeypox is a zoonotic Orthopoxvirus with a presentation similar to smallpox. Clinical differentiation of the disease from smallpox and varicella is difficult. Laboratory diagnostics are principal components to identification and surveillance of disease, and new tests are needed ...

Last Updated: 25 Dec 2013

Go To URL
Comparative pathology of smallpox and monkeypox in man and macaques.
 

Author(s): J A Cann, P B Jahrling, L E Hensley, V Wahl-Jensen

Journal: J. Comp. Pathol.. 2013 Jan;148(1):6-21.

 

In the three decades since the eradication of smallpox and cessation of routine vaccination, the collective memory of the devastating epidemics caused by this orthopoxvirus has waned, and the human population has become increasingly susceptible to a disease that remains high on the ...

Last Updated: 29 Jan 2013

Go To URL
Whither monkeypox vaccination.
 

Author(s): Anne W Rimoin, Barney S Graham

Journal: Vaccine. 2011 Dec;29 Suppl 4():D60-4.

 

Monkeypox (MPX) is a virulent orthopoxvirus that is endemic in some regions of Central Africa. MPX incidence has been rising since the cessation of routine smallpox immunization. While it causes significant disease, there is limited person-to-person spread, the incidence is still ...

Last Updated: 10 Apr 2012

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Tecovirimat (ST-246) Treatment for Orthopox Virus Exposure
 

Status: Available

Condition Summary: Smallpox; Monkeypox

 

Last Updated: 16 Apr 2015

Go to URL