Monkeypox

Common Name(s)

Monkeypox

Monkeypox is a virus that is very dangerous to humans. It is similar in symptoms to smallpox, and occurs sporadically in parts of Africa. Human monkepox first appeared in 1970 in the Democratic Republic of Congo, and since then has been reported in rural areas of the Congo Basin and western African. The disease can be spread through direct contact with the blood, bodily fluids, or rashes of infected animals, and also through transmission from human-to-human, through close contact. Signs and symptoms of monkeypox include fever, intense headache, swelling of the lymph node, muscle ache, and an intense lack of energy. Symptoms can then progress to skin eruptions on the palms of the hands and soles of the feet. Symptoms of monkeypox typically last 14 to 21 days, and the disease can be fatal.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Monkeypox" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Monkeypox" returned 99 free, full-text research articles on human participants. First 3 results:

Enhancing case definitions for surveillance of human monkeypox in the Democratic Republic of Congo.
 

Author(s): Lynda Osadebe, Christine M Hughes, Robert Shongo Lushima, Joelle Kabamba, Beatrice Nguete, Jean Malekani, Elisabeth Pukuta, Stomy Karhemere, Jean-Jacques Muyembe Tamfum, Emile Wemakoy Okitolonda, Mary G Reynolds, Andrea M McCollum

Journal:

 

Human monkeypox (MPX) occurs at appreciable rates in the Democratic Republic of Congo (DRC). Infection with varicella zoster virus (VZV) has a similar presentation to that of MPX, and in areas where MPX is endemic these two illnesses are commonly mistaken. This study evaluated the ...

Last Updated: 11 Sep 2017

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Characterization of Monkeypox virus infection in African rope squirrels (Funisciurus sp.).
 

Author(s): Elizabeth A Falendysz, Juan G Lopera, Jeffrey B Doty, Yoshinori Nakazawa, Colleen Crill, Faye Lorenzsonn, Lem's N Kalemba, Monica D Ronderos, Andres Mejia, Jean M Malekani, Kevin Karem, Darin S Carroll, Jorge E Osorio, Tonie E Rocke

Journal:

 

Monkeypox (MPX) is a zoonotic disease endemic in Central and West Africa and is caused by Monkeypox virus (MPXV), the most virulent Orthopoxvirus affecting humans since the eradication of Variola virus (VARV). Many aspects of the MPXV transmission cycle, including the natural host ...

Last Updated: 22 Aug 2017

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Presumptive risk factors for monkeypox in rural communities in the Democratic Republic of the Congo.
 

Author(s): Claire A Quiner, Cynthia Moses, Benjamin P Monroe, Yoshinori Nakazawa, Jeffrey B Doty, Christine M Hughes, Andrea M McCollum, Saturnin Ibata, Jean Malekani, Emile Okitolonda, Darin S Carroll, Mary G Reynolds

Journal:

 

Monkeypox virus (MPXV), a close relative of Variola virus, is a zoonotic virus with an unknown reservoir. Interaction with infected wildlife, bites from peri-domestic animals, and bushmeat hunting are hypothesized routes of infection from wildlife to humans. Using a Risk Questionnaire, ...

Last Updated: 13 Feb 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Monkeypox" returned 6 free, full-text review articles on human participants. First 3 results:

Comparative pathology of smallpox and monkeypox in man and macaques.
 

Author(s): J A Cann, P B Jahrling, L E Hensley, V Wahl-Jensen

Journal: J. Comp. Pathol.. 2013 Jan;148(1):6-21.

 

In the three decades since the eradication of smallpox and cessation of routine vaccination, the collective memory of the devastating epidemics caused by this orthopoxvirus has waned, and the human population has become increasingly susceptible to a disease that remains high on the ...

Last Updated: 29 Jan 2013

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Whither monkeypox vaccination.
 

Author(s): Anne W Rimoin, Barney S Graham

Journal: Vaccine. 2011 Dec;29 Suppl 4():D60-4.

 

Monkeypox (MPX) is a virulent orthopoxvirus that is endemic in some regions of Central Africa. MPX incidence has been rising since the cessation of routine smallpox immunization. While it causes significant disease, there is limited person-to-person spread, the incidence is still ...

Last Updated: 10 Apr 2012

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Monkeypox virus and insights into its immunomodulatory proteins.
 

Author(s): Jessica R Weaver, Stuart N Isaacs

Journal: Immunol. Rev.. 2008 Oct;225():96-113.

 

Monkeypox is a disease that is endemic in Central and Western Africa. However, in 2003, there was an outbreak in the United States, representing the first documented monkeypox cases in the Western hemisphere. Although monkeypox virus is less fatal and not as transmissible as variola ...

Last Updated: 7 Oct 2008

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 27 Feb 2017

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Tecovirimat (ST-246) Treatment for Orthopox Virus Exposure
 

Status: Available

Condition Summary: Smallpox; Monkeypox

 

Last Updated: 10 Nov 2016

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