Monkeypox

Common Name(s)

Monkeypox

Monkeypox is a virus that is very dangerous to humans. It is similar in symptoms to smallpox, and occurs sporadically in parts of Africa. Human monkepox first appeared in 1970 in the Democratic Republic of Congo, and since then has been reported in rural areas of the Congo Basin and western African. The disease can be spread through direct contact with the blood, bodily fluids, or rashes of infected animals, and also through transmission from human-to-human, through close contact. Signs and symptoms of monkeypox include fever, intense headache, swelling of the lymph node, muscle ache, and an intense lack of energy. Symptoms can then progress to skin eruptions on the palms of the hands and soles of the feet. Symptoms of monkeypox typically last 14 to 21 days, and the disease can be fatal.

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Condition Specific Organizations

Following organizations serve the condition "Monkeypox" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Monkeypox" returned 105 free, full-text research articles on human participants. First 3 results:

Last Updated: 31 Dec 1969

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Emergence of Monkeypox - West and Central Africa, 1970-2017.
 

Author(s): Kara N Durski, Andrea M McCollum, Yoshinori Nakazawa, Brett W Petersen, Mary G Reynolds, Sylvie Briand, Mamoudou Harouna Djingarey, Victoria Olson, Inger K Damon, Asheena Khalakdina

Journal:

 

The recent apparent increase in human monkeypox cases across a wide geographic area, the potential for further spread, and the lack of reliable surveillance have raised the level of concern for this emerging zoonosis. In November 2017, the World Health Organization (WHO), in collaboration ...

Last Updated: 31 Dec 1969

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Enhancing case definitions for surveillance of human monkeypox in the Democratic Republic of Congo.
 

Author(s): Lynda Osadebe, Christine M Hughes, Robert Shongo Lushima, Joelle Kabamba, Beatrice Nguete, Jean Malekani, Elisabeth Pukuta, Stomy Karhemere, Jean-Jacques Muyembe Tamfum, Emile Wemakoy Okitolonda, Mary G Reynolds, Andrea M McCollum

Journal:

 

Human monkeypox (MPX) occurs at appreciable rates in the Democratic Republic of Congo (DRC). Infection with varicella zoster virus (VZV) has a similar presentation to that of MPX, and in areas where MPX is endemic these two illnesses are commonly mistaken. This study evaluated the ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Monkeypox" returned 7 free, full-text review articles on human participants. First 3 results:

Review of poxvirus: emergence of monkeypox.
 

Author(s): A Morand, S Delaigue, J J Morand

Journal: Med Sante Trop. 2017 Feb;27(1):29-39.

 

This article reviews the different types of poxvirus infections. Smallpox, although eradicated, must continue to be monitored because of the potential risk of accidental or voluntary (by bioterrorism) reintroduction. Monkeypox and cowpox viruses are considered to be emergent today ; ...

Last Updated: 31 Dec 1969

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Comparative pathology of smallpox and monkeypox in man and macaques.
 

Author(s): J A Cann, P B Jahrling, L E Hensley, V Wahl-Jensen

Journal: J. Comp. Pathol.. 2013 Jan;148(1):6-21.

 

In the three decades since the eradication of smallpox and cessation of routine vaccination, the collective memory of the devastating epidemics caused by this orthopoxvirus has waned, and the human population has become increasingly susceptible to a disease that remains high on the ...

Last Updated: 31 Dec 1969

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Whither monkeypox vaccination.
 

Author(s): Anne W Rimoin, Barney S Graham

Journal: Vaccine. 2011 Dec;29 Suppl 4():D60-4.

 

Monkeypox (MPX) is a virulent orthopoxvirus that is endemic in some regions of Central Africa. MPX incidence has been rising since the cessation of routine smallpox immunization. While it causes significant disease, there is limited person-to-person spread, the incidence is still ...

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 27 Feb 2017

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Tecovirimat (ST-246) Treatment for Orthopox Virus Exposure
 

Status: Available

Condition Summary: Smallpox; Monkeypox

 

Last Updated: 1 Dec 2017

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